CASE REPORT: ISOLATED SEVERE THROMBOCYTOPENIA IN A PATIENT WITH SUSPECTED SARS COV 2 INFECTION

2021 ◽  
pp. 18-19
Author(s):  
Rohit S B ◽  
Lokesh S
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Immune System ◽  
Respiratory Symptoms ◽  
Blood Count ◽  
Complete Blood Count ◽  
Nasopharyngeal Swab ◽  
Severe Thrombocytopenia ◽  
Rt Pcr ◽  
High Resolution Computed Tomography

COVID 19 is an ongoing pandemic which can cause severe respiratory symptoms, with the involvement of renal, liver, haematopoietic, neurological and immune system. This case report describes a case of COVID 19 patient who presented with anosmia, loss of taste, without any other respiratory symptoms. Radiological examination of chest through High Resolution Computed Tomography (HRCT) revealed CORADS 5 with a CT severity score of 4/25, but blood investigations revealed thrombocytopenia with leukopenia. RT PCR nasopharyngeal swab was negative. Complete blood count revealed severe thrombocytopenia after other causes of fever with thrombocytopenia were ruled out. It is important to monitor and evaluate all atypical and rare presentations of COVID 19, such as isolated thrombocytopenia.

scholarly journals Covid-19 infection without respiratory symptoms: case report of diagnosing a 14 year-old patient with acute abdomen 

2020 ◽  
Author(s):  
Ladan Goshayeshi ◽  
Nasrin Milani ◽  
Robert Bergqueist ◽  
Sayyed Majid Sadrzadeh ◽  
Farnood Rajabzadeh ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Case Report ◽  
Respiratory Rate ◽  
Respiratory Symptoms ◽  
Free Fluid ◽  
Nasopharyngeal Swab ◽  
High Resolution Computed Tomography ◽  
Respiratory Involvement ◽  
Chest X Ray ◽  
Gastrointestinal Manifestation

Abstract Background. Coronavirus Disease 2019 (Covid-19) is expanding worldwide. Although it seems to be a purely respiratory disease, occasional reports of lesions in other organs have been published. We report here an asymptomatic child Covid-19 patient with the main symptom of abdominal pain distension and without any respiratory symptoms.Case presentation. A 14 year-old male patient without respiratory involvement but with main complaints of fever, malaise, anorexia, and severe abdominal pain was admitted to a hospital in Mashhad, Iran. Following general anaesthesia, laparotomy revealed distension of the small intestine and an adhesive ileo-caecal band that had produced ileum herniation without free fluid in the abdomen. The band was surgically severed and the patient referred to the recovery room. Because of pulse rate of 36-40 per min and respiratory rate of 140 and a saturated O2 of 86%, the patient was referred to the intensive care unit. Chest X-ray and high-resolution computed tomography of the lungs showed bilateral, diffuse, peripheral dense areas of ground-glass appearance. A nasopharyngeal swab for Covid-19 diagnosis, ordered due to lymphopenia together with these diffuse lung infiltrations, showed a positive result. This led to drug treatment with lopinavir/ritonavir, hydroxychloroquine, ribavirin/oseltamivir and meropenem. The patient was febrile and developed tachycardia on the third day accompanied with a respiratory rate of 44/min. At this point, tracheal intubation was done but the patient died after 3 hours due to cardiac arrest.Conclusions. The case report brings forth the hypothesis that the gastrointestinal manifestation may be untypical symptoms of Covid-19 infection, and highlights the importance for the diagnosis to be based on combined laboratory-based data and scanning imagery.

scholarly journals An Unusual Case of Dengue Fever with Necrotising Pneumonia

2020 ◽  
Author(s):  
Nazeem Fathima ◽  
Balamma Sujatha ◽  
Shami RP Kumar ◽  
S Rajesh
Keyword(s):  
Computed Tomography ◽  
Pleural Effusion ◽  
High Resolution ◽  
Dengue Fever ◽  
Respiratory Symptoms ◽  
Unusual Case ◽  
Left Lung ◽  
Female Child ◽  
High Resolution Computed Tomography ◽  
Thin Walled

Concurrent bacteremia in patients with dengue fever is rarely reported. Two and a half-year-old female child with fever, cough and cold for six days presented to Emergency Room (ER) with tachypnea, tachycardia and hepatomegaly. Investigations revealed dengue fever. Respiratory symptoms probed us to investigate the case further. High-Resolution Computed Tomography (HRCT) thorax showed moderate pleural effusion with collapse consolidation of left lung and a thin walled cavity with septations and fluid in left upper lobe. Child was treated with injection meropenem and vancomycin successfully.

scholarly journals Texidor’s twinge a rare cause of benign paroxysmal chest pain

2020 ◽  
Vol 0 (Ahead of Print) ◽  
Author(s):  
Narendra Kumar ◽  
Rachna Pasi ◽  
Swathi Chacham ◽  
Prashant Kumar Verma
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Chest Pain ◽  
Deep Inspiration ◽  
High Resolution Computed Tomography ◽  
Cardiac Enzymes ◽  
Case Summary ◽  
Long Duration ◽  
Case Characteristics ◽  
Lying Down

Objective: Precordial catch syndrome was described by Miller and Texidor in 1955. It deserves wider recognition because it is rarely discussed in the differential diagnosis of precordial pain. Case summary: Case characteristics include a young 8-year-old female that presented with 4th episode of chest pain to the hospital. On attempting maneuver like deep breaths slowly in lying down position, pain subsided within 5 minutes although all other modalities of chest pain investigation as electrocardiography, echocardiography, chest high-resolution computed tomography, cardiac enzymes were normal. Discussion and conclusion: Various maneuvers like lying down or sitting upright and attempting deep inspiration tends to help in such conditions. This case report is reporting an unusual presentation of this syndrome due to its long duration of episode than the duration described in the previous reports. Prognosis is good. Key words: precordial catch syndrome, sharp chest pain, sagged posture, Texidor’s twinge, case report

scholarly journals Rapid identification of SARS-CoV-2-infected patients at the emergency department using routine testing

2020 ◽  
Author(s):  
Steef Kurstjens ◽  
Armando van der Horst ◽  
Robert Herpers ◽  
Mick W.L. Geerits ◽  
Yvette C.M. Kluiters-de Hingh ◽  
...  
Keyword(s):  
Respiratory Symptoms ◽  
Demographic Data ◽  
Characteristic Curve ◽  
Rapid Identification ◽  
Nasopharyngeal Swab ◽  
Rt Pcr ◽  
Validation Population ◽  
Score Model ◽  
Using Data ◽  
Novel Coronavirus

ABSTRACTBackgroundThe novel coronavirus disease 19 (COVID-19), caused by SARS-CoV-2, spreads rapidly across the world. The exponential increase in the number of cases has resulted in overcrowding of emergency departments (ED). Detection of SARS-CoV-2 is based on an RT-PCR of nasopharyngeal swab material. However, RT-PCR testing is time-consuming and many hospitals deal with a shortage of testing materials. Therefore, we aimed to develop an algorithm to rapidly evaluate an individual’s risk of SARS-CoV-2 infection at the ED.MethodsIn this multicenter retrospective study, routine laboratory parameters (C-reactive protein, lactate dehydrogenase, ferritin, absolute neutrophil and lymphocyte counts), demographic data and the chest X-ray/CT result from 967 patients entering the ED with respiratory symptoms were collected. Using these parameters, an easy-to-use point-based algorithm, called the corona-score, was developed to discriminate between patients that tested positive for SARS-CoV-2 by RT-PCR and those testing negative. Computational sampling was used to optimize the corona-score. Validation of the model was performed using data from 592 patients.ResultsThe corona-score model yielded an area under the receiver operating characteristic curve of 0.91 in the validation population. Patients testing negative for SARS-CoV-2 showed a median corona-score of 3 versus 11 (scale 0-14) in patients testing positive for SARS-CoV-2 (p<0.001). Using cut-off values of 4 and 11 the model has a sensitivity and specificity of 96% and 95%, respectively.ConclusionThe corona-score effectively predicts SARS-CoV-2 RT-PCR outcome based on routine parameters. This algorithm provides the means for medical professionals to rapidly evaluate SARS-CoV-2 infection status of patients presenting at the ED with respiratory symptoms.

scholarly journals COVID-19 related complete blood count changes among asymptomatic pregnant women

2021 ◽  
Vol 10 (2) ◽  
Author(s):  
Waleed F Gharib ◽  
Hesham Nasser ◽  
Ahmed M.A. Sobh ◽  
Rasha E Khamees
Keyword(s):  
Antenatal Care ◽  
Pregnant Women ◽  
Eosinophil Count ◽  
Blood Count ◽  
Complete Blood Count ◽  
Confirmatory Test ◽  
Nasopharyngeal Swab ◽  
Care Clinic ◽  
Entire Study ◽  
Study Population

Objective: To evaluate complete blood count (CBC) changes that suggest coronavirus disease-2019 (COVID-19) among asymptomatic pregnant women attending routine antenatal care Methods: A cross-sectional study included 187 healthy pregnant women who were attending the antenatal care clinic of a tertiary University hospital between March and June 2020. After a thorough history and examinations, a venous blood sample was taken from each participant for complete and differential blood counts. Those who showed CBC findings suggestive of COVID-19 were further scheduled for a nasopharyngeal swab for detection of SARS-CoV-2 specific antigens through polymerase chain reaction (PCR). Results: We found 5.3% (n=10) of the study population showed CBC changes that are suggestive of COVID-19. When they were scheduled for nasopharyngeal swab for a PCR confirmatory test, 30% (n=3) of them were PCR positive (which represented 1.6% of the entire study population). The most frequently encountered COVID-19-suggestive change in peripheral blood leukocyte differential counts was leucopenia (100%), followed by decreased eosinophil count (50%), then neutropenia and lymphocytopenia (30%). Conclusions: Certain differential leucocyte count changes (leucopenia, neutropenia, lymphocytopenia and decreased eosinophil count) among asymptomatic pregnant women might be related to COVID-19 infection and may indicate a need for further testing.

scholarly journals Covid-19 only with gastrointestinal (GI) symptoms: case report of a 14-year-old patient 

2020 ◽  
Author(s):  
Ladan Goshayeshi ◽  
Nasrin Milani ◽  
Robert Bergqueist ◽  
Sayyed Majid Sadrzadeh ◽  
Farnood Rajabzadeh ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Case Report ◽  
Free Fluid ◽  
Nasopharyngeal Swab ◽  
Asymptomatic Child ◽  
High Resolution Computed Tomography ◽  
Gi Symptoms ◽  
Chest X Ray ◽  
Gastrointestinal Manifestation ◽  
Diffuse Lung

Abstract Coronavirus Disease 2019 (Covid-19) is expanding worldwide. Although it seems to be a purely respiratory disease, occasional reports of lesions in other organs have been published. We report here an asymptomatic child Covid-19 patient with the main symptom of abdominal pain distension and without any respiratory symptoms. A 14-year-old male patient with main complaints of fever, malaise, anorexia, and severe abdominal pain was admitted to a hospital in Mashhad, Iran. Laparotomy revealed distension of the small intestine and an adhesive ileo-caecal band that had produced ileum herniation without free fluid in the abdomen. Chest X-ray and high-resolution computed tomography of the lungs showed bilateral, diffuse, peripheral dense areas of ground-glass appearance. A nasopharyngeal swab for Covid-19 diagnosis, ordered due to lymphopenia together with these diffuse lung infiltrations, showed a positive result. This led to drug treatment with lopinavir/ritonavir, hydroxychloroquine, ribavirin/oseltamivir and meropenem. The patient was febrile and developed tachycardia on the third day accompanied with a respiratory rate of 44/min. At this point, tracheal intubation was done but the patient died after 3 hours due to cardiac arrest. The case report brings forth the hypothesis that the gastrointestinal manifestation may be untypical symptoms of Covid-19 infection, and highlights the importance for the diagnosis to be based on combined laboratory-based data and scanning imagery.

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