scholarly journals DRY-EYE DISEASE AMONG MEDICAL PROFESSIONALS IN A TERTIARY CARE HOSPITAL IN WESTERN UP DURING THE LOCKDOWN PERIOD 2020 – A CROSSSECTIONAL STUDY.

2020 ◽  
pp. 1-4
Author(s):  
Neelima Mehrotra ◽  
Amrita Bajpai Mishra ◽  
Alia Yamin ◽  
Ruchi Saxena ◽  
Ashwani Srivastava
Keyword(s):  
Dry Eye ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Medical Professionals ◽  
Care Hospital ◽  
Human Beings ◽  
Ocular Surface Disease Index ◽  
Cross Sectional

Objective : To estimate the prevalence of dry-eye disease (DED) among medical professionals in a tertiary care hospital in Western UP during the lockdown period 2020. Materials & Methods : This was a cross-sectional hospital-based, observational study from 7th May 2020 till 14th May 2020, that included 50 medical professionals as subjects. The study compares the increase in the number of hours spent on Visual Display Terminals (VDTs) before and during the lockdown period 2020. This in-turn led to numerous ill-effects on human beings, out of which ocular manifestations like dry-eye disease has been on the rise. The study has been carried out in the form of questionnaire survey data – Ocular Surface Disease Index (OSDI) asking about the symptoms and various other parameters, related to dry eye. Results : The mean number of hours spent on VDTs before lockdown was 2.82±1.32 hours and during lockdown was 6.26±4.76 hours. In accordance with the OSDI scoring, 23/50 subjects developed DED. Out of these, 28% (14/50) had mild DED, 16% (8/50) had moderate DED, and only 2% (1/50) had severe DED. Prevalence of dry eye was directly proportionate to exposure time to VDT during the lockdown. Conclusion : The prevalence of dry-eye disease (DED) among medical professionals during the lockdown period 2020 was 46%. This was attributed to the increased dependence on VDTs for various purposes.

Frequency and impact of individual symptoms on quality of life in dry eye disease in patients presenting to a tertiary care hospital

2021 ◽  
pp. 1-16
Author(s):  
Saba Ali Arif ◽  
Muhammad Ifraheem Khan ◽  
Muhammad Salman Abid ◽  
Ayla Babar ◽  
Mohammad Ali Arif ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Dry Eye ◽  
Tertiary Care ◽  
Tear Film ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Care Hospital ◽  
Cross Sectional ◽  
Department Of Ophthalmology

Abstract Objective: To assess the frequency of symptoms and impact on quality of life in individuals with dry eye disease. Methods: The cross-sectional, study was conducted from December 2018 to June 2019 at the outpatient clinic of the Department of Ophthalmology, Pakistan Institute of Medical Sciences, Islamabad, Pakistan, and comprised dry eye disease patients aged at least 13 years with ocular burning sensation, lacrimation, grittiness, photophobia, redness or itching. Tear Film Breakup time <10 sec and / or positive ocular surface staining >5 corneal spots, >9 conjunctival spots, lid margin staining ?2mm in length were used to diagnose the disease. Data was collected using the Dry Eye Quality of Life Score questionnaire. Data was analysed using SPSS 25. Results: of the 191 patients, 135(71%) were females and 56(29%) were males. The overall mean age was 39.8±16.6 years. Itching 155(81.2%), watering 151(79.1%) and burning 124(64.9%) were the most frequent symptoms, with watering (p<0.001) and photophobia (p=0.012) significantly impacting quality of life. Conclusions: The most common symptoms among patients of dry eye disease affecting their quality of life were itching, watering, burning, photophobia and low mood. Key Words: Quality of life in dry eye disease, Dry eye disease, Lacrimation, Photophobia, Continuous...

scholarly journals Comparative analysis of efficacy and adverse effects of tacrolimus vs cyclosporine in chronic dry eye disease: a tertiary care hospital based study

2018 ◽  
Vol 7 (11) ◽  
pp. 2216
Author(s):  
Zeenat Fatima ◽  
Rakesh Chandra Chaurasia ◽  
Satya Prakash Singh
Keyword(s):  
Dry Eye ◽  
Tertiary Care ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Eye Drops ◽  
Care Hospital ◽  
Ocular Surface Disease Index ◽  
Presenting Symptoms ◽  
Group 2 ◽  
Group 1

Background: Dry eye disease (DED) is the very common and underdiagnosed ocular condition affecting vision, quality of life, and the outcomes of cataract or refractive surgery. Dry eye disease (DED), either alone or in combination with other conditions, is a frequent cause of ocular irritation that leads the patients to seek ophthalmic care. Due to a wide variety of presenting symptoms, it is often unrecognized and this causes great frustration of the patient and treating physician. While these symptoms often improve with appropriate treatment, usually in majority of the cases the disease may not be curable. Aim of the study was to compare the efficacy of tacrolimus and cyclosporine in dry eye disease.Methods: This was a single centred, 3 months prospective study. Patients with unilateral or bilateral dry eye disease and an ocular surface disease index score >12, atleast one eye with schirmer score <5mm and TBUT <10 s were enrolled in the study. The enrolled patients were randomly divided into two groups, twenty-five patients in Group 1 and twenty three patients in Group 2 completed the follow up. Group 1(n =25) who received 0.03% tacrolimus eye ointment twice daily for consecutive 3 months and Group 2 (n= 23) received 0.05% cyclosporine eye drops twice daily for consecutive 3 months the primary efficacy outcome was Schirmer score after 3 months. The secondary outcomes were TBUT and adverse effects.Results: After 3 months, both the treatment groups showed significant improvement in mean Schirmer score (p<0.001) and mean TBUT (p <0.0001). However, on comparing both the groups, mean Schirmer score and mean TBUT, results were comparable. No patient discontinued treatment because of minor ocular adverse effects.Conclusions: Dry eye patients demonstrated improvement in Schirmer score and TBUT after 3 months of treatment with tacrolimus 0.03% ointment and cyclosporine 0.05% eye drops.

scholarly journals Dry eye disease among Glaucoma patients on topical hypotensive medications, in a tertiary hospital, Ethiopia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Miraf Sahlu ◽  
Abeba T. Giorgis
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Signs And Symptoms ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Eye Drops ◽  
Schirmer Test ◽  
Ocular Surface Disease Index ◽  
Cross Sectional ◽  
Corneal Staining

Abstract Background Dry eye disease is a multifactorial disease; causing various ocular symptoms with potential damage to the ocular surface. Applying hypotensive eye drops are presumed to initiate or exacerbate existing dry eye disease. The purpose of this study was to determine the frequency of signs and symptoms and severity of dry eye disease among glaucoma patients on topical hypotensive medications and controls. Methods A cross-sectional comparative study, involving 320 glaucoma patients and controls. Ocular Surface Disease Index (OSDI) symptoms score and Schirmer, tear breakup time and corneal staining tests were used to assess dry eye disease. Data was analyzed using SPSS version 24 software; p-value less than 0.05 was considered as statistically significant. Results Among the 160 study glaucoma patients, the mean duration of topical hypotensive medication use was 5.2 ± 5.21 years (range, 4 months - 32 years). Mild to severe level of OSDI score was found in 122 (76%) glaucoma patients and in 137 (86%) controls (p = 0.033). Mild to sever abnormal clinical tests in the glaucoma patients and control, respectively, were 106 (66%) vs 80 (50%) corneal staining (p = 0.045), 79 (49%) vs 72 (45%) TBUT (p = 0.021), and 91 (57%) vs 83 (52%) Schirmer test (p = 0.242). Test results at the level of sever: 2 (1%) vs 0 (0%) corneal staining, 50 (31%) vs 39 (24%) TBUT and 65 (41%) vs 60 (38%) Schirmer test in the glaucoma patents and controls, respectively. Corneal staining and TBUT had correlation with the number of drugs (p = 0.004 and 0.031, respectively), and more relationship of the two tests with total number of drops applied per day (p = 0.01 and p <  0.001, respectively). Patients on pilocarpine and timolol had more corneal staining and lower TBUT [(p = 0.011 and p <  0.001) and (p = 0.04 and 0.012), respectively]. Conclusions The study has identified glaucoma patients to be more affected by dry eye disease than non-glaucoma patients, and presence of significantly lower TBUT and higher corneal staining in the glaucoma patients on multidrops and multidose per day. We recommend consideration of evaluation and management of DED for glaucoma patients on multidrops and multidose hypotensive medications.

scholarly journals A comparative assessment of dry eye disease among outdoor street sweepers and indoor office cleaners

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Chigozie I. Echieh ◽  
Bassey A. Etim ◽  
Chidiebere Peter Echieh ◽  
Taiwo Oyeniyi ◽  
Jeff Ajewole
Keyword(s):  
Dry Eye ◽  
Cross Sectional Study ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Ocular Surface Disease Index ◽  
Simultaneous Exposure ◽  
Cross Sectional ◽  
Systematic Random Sampling ◽  
Schirmer’S Test ◽  
Multi Stage

Abstract Background Occupational predisposition to dry eye disease is known. Simultaneous exposure to multiple factors may pose more risk. Street sweepers are exposed to sunlight in addition to dust which all sweepers are exposed to. Tropical climate predisposes to significant exposure to sunlight. Combined exposure to dust and sunlight may lead to a synergy of factors. This study aims to assess the prevalence of dry eye disease (DED) amongst Street sweepers and Office cleaners in Calabar metropolis. Methods A cross-sectional study was conducted among street sweepers and office cleaners. A systematic random sampling and multi-stage sampling method were used to select street sweepers (n = 115) and office cleaners (n = 115) respectively for the study. A pretested semi-structured interviewer-administered questionnaire was used to obtain information after which the respondents had an ophthalmic examination. An assessment of DED was done with Ocular Surface Disease Index (OSDI) questionnaire, Schirmer’s test, and tear break up time (TBUT). OSDI scores of 33 and above; Schirmer’s test readings of < 10 mm wetting in 5 min and a TBUT of less than 10s in either eye were considered as positive dry eye disease. Results The majority of respondents were females 215(93.5%) compared to males 15 (6.5%). The overall mean age of respondents was 40.96 ± 9.8 years. The average OSDI score, Schirmer’s test as well as TBUT among participants was 26.4 ± 16.0, 16.44 ± 9.52 mm, and 12.38 ± 4.53 s respectively. The prevalence of DED among Street sweepers was 35.7% compared to 20% among office cleaners using the OSDI questionnaire (p = 0.352). The prevalence of DED among street sweepers was 32.2% compared to 30.4% among Office cleaners using the Schirmer’s test. (p = 0.73) The TBUT reported a prevalence of 38.3% of DED among Street sweepers compared to 32.2% in office cleaners. (p = 0.48) Overall; the prevalence of dry eye disease among Street sweepers and office cleaners using OSDI score, Schirmers test, as well as TBUT were not statistically significant (> 0.05) Street Sweepers had higher odds of developing dry eye disease compared to office cleaners (OR = 2.085; C.I. =1.106–3.929; p = 0.02). Negative correlation coefficient was observed between TBUT and OSDI (rs = − 0.102; p = 0.125). This was not statistically significant. Conclusion Street sweepers had a higher prevalence of dry eye disease compared to office cleaners due to a higher risk of increased exposure to environmental factors such as dust, smoke, and sunlight. This effect is possibly due to a synergy of factors. Studies on dose-response are warranted.

scholarly journals Dry Eye Disease among Pregnant Women at a Tertiary Care Hospital in Kathmandu

2020 ◽  
Vol 22 (3) ◽  
pp. 146-152
Author(s):  
Aparna Rizyal ◽  
B Shrestha ◽  
A Khadka
Keyword(s):  
Pregnant Women ◽  
Dry Eye ◽  
Tertiary Care ◽  
College Teaching ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Care Hospital ◽  
Dry Eyes ◽  
Schirmer’S Test ◽  
Woman's Body

Pregnancy is characterized by many significant changes in a woman’s body which helps develop the fetus optimally. During pregnancy, there is marked maternal endocrine upregulation, hormonal profile modifications and interactions leading to dry eyes. Pregnancy causes most parts of a woman’s body to change, and the eyes are no exception. Dry eye disease is a common pregnancy problem that usually begins towards the end of the first trimester. Since, there is a dearth of literature on dry eye disease during pregnancy in Nepal, a study was conducted to estimate the prevalence of dry eyes disease among pregnant women and to find its association with socio-demographic characteristics and their gestation period, at Nepal Medical College Teaching Hospital. A total of 84 pregnant women in different trimesters volunteered for this study. The upper and lower limits for estimated mean age were 26.67 years to 25.03 years at 95% confidence level. The prevalence of dry eyes was 89.3% by tear break up time test and 27.4% by Schirmer’s test respectively. The association between gestational age and dry eyes by Schirmer’s test was statistically significant.

scholarly journals A Comparative Assessment of Dry Eye Disease Among Outdoor Street Sweepers and Indoor Office Cleaners

2020 ◽  
Author(s):  
Chigozie Ifeoma Echieh ◽  
Bassey A Etim ◽  
Chidiebere Peter Echieh ◽  
Jeff Ajewole
Keyword(s):  
Dry Eye ◽  
Cross Sectional Study ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Ocular Surface Disease Index ◽  
Simultaneous Exposure ◽  
Cross Sectional ◽  
Multiple Risk Factors ◽  
Schirmer’S Test ◽  
Multi Stage

Abstract Background:Occupational predisposition to dry eye disease is known. Simultaneous exposure to multiple factors may pose more risk. Street sweepers are exposed to sunlight in addition to dust which all sweepers are exposed to. This study aims to assess the prevalence of dry eye disease (DED) amongst Street sweepers and Office cleaners in Calabar metropolis.Methods:A cross sectional study was conducted among street sweepers and office cleaners. A systematic random sampling and multi-stage sampling method was used to select street sweepers (n=115) and office cleaners (n=115) respectively for the study. A pretested semi-structured interviewer administered questionnaire was used to obtain information after which the respondents had an ophthalmic examination. An assessment of DED was done with Ocular Surface Disease Index (OSDI) questionnaire, Schirmer’s test and tear break up time (TBUT).Results:Majority of respondents were females 215(93.5%) compared to males 15 (6.5%). The overall mean age of respondents was 40.96 ± 9.8 years. The prevalence of DED among Street sweepers was 35.7% compared to 20% among office cleaners using the OSDI questionnaire. The prevalence of DED among street sweepers was 32.2% compared to 30.4% among Office cleaners using the Schirmer’s test. The TBUT reported a prevalence of 38.3% of DED among Street sweepers compared to 32.2% in Office cleaners.Conclusion:This study concluded that street sweepers had higher odds of developing dry eye disease compared to office cleaners. This effect is possibly due to synergy of factors. Studies on dose response are warranted. Strict use of protective gears that protect from multiple risk factors are recommended.

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