KNOWLEDGE, ATTITUDE AND PRACTICE OF DIET CONTROLAND EXERCISE IN PATIENTS WITH DIABETES MELLITUS TYPE-2 IN BISHA, KINGDOM OF SAUDI ARABIA.

2021 ◽  
pp. 61-64
Author(s):  
Saad Salem Mohammed Alqarni ◽  
Ibrahim Awad Eljack ◽  
Vijaya Marakala ◽  
Mohammad Muzaffar Mir

Background: Diabetes mellitus type-2 (DM-T2) constitutes a major public health concern and is one of the fastest growing diseases worldwide, projected to affect 693 million adults by 2045. Devastating macrovascular complications (cardiovascular disease) and microvascular complications (diabetic kidney disease, diabetic retinopathy and neuropathy) lead to increased mortality, blindness, kidney failure and an overall decreased quality of life in individuals with diabetes. An optimum glycemic control is a key to reduce the associated complications of DM-T2 and can be achieved by assessing the knowledge and attitude of patients in the management of the diseases followed by proper counseling. Methodology: This is a descriptive cross-sectional study and was carried out on 400 diabetic patients (DM-T2) who attended diabetic center in King Abdullah Hospital, Bisha. A questionnaire was used for data collection from patients in the outpatient department after taking their prior permission. SPSS v.20 was used to analyses the data. Chi-square test was used to test the relationship between the categorical variables in the attitude and practice of diet control in patients with DM-T2 Results: Our results indicated a better understanding of the role of diet (73%) while as only about 42.5% of patients had a good knowledge about the role of exercise in the control of DM-T22. Majority of patients (61.5%) regularly visited their treating physicians and 47.5 % of patients reported doing regular exercise, 54.75% patients conrmed the regular consumption of vegetables and fruits. Amajority of patients (68.25 %) reported that they enquire from their treating physicians about the role of diet and exercise in the prevention of complication associated with DM-T2. Conclusions: Our study revealed a good level of knowledge, attitude and practices of diet control and exercise among the diabetes patients attending one diabetic center in Bisha city of Aseer region of KSA. There is a need for more such studies involving a bigger sample size of the diabetic patients from the region.

2021 ◽  
Vol 16 (8) ◽  
pp. 98-102
Author(s):  
Hashim Abdul Razzaq Iman ◽  
Hussein Murtadha Jinan

Diabetes mellitus type 2 (T2DM) results from beta cell dysfunction or reduced action of insulin responsive. The objective of this study was to examine the relevance between blood sugar, the activity of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in fasting women diabetic patients in different durations. A total of sixty-eight women were divided into three groups: first a healthy group – non-diabetic (twenty-six women), second and third groups (twenty-one) were diabetic patients of age 35 – 50 and 51 – 69 years respectively. Serum fasting blood sugar was significantly (P < 0.05) elevated to 181.60 mg/dl in female patients with 35 – 50 years. The same effect happened in activity of AST to 32.91 u/L in 51 – 69 years and ALT was 28.43 u/L in 35 – 50 years. No significant differences were found between the aged and fasting blood sugar, AST and ALT in diabetic patients. The correlation factor (r) between fasting blood sugar and the activity of ALT was highly significant.


2016 ◽  
Vol 28 (03) ◽  
pp. 1650016
Author(s):  
Yu Chu-Su ◽  
Chien-Sheng Liu ◽  
Ruey-Shin Chen ◽  
Chii-Wann Lin

Background: The result of a standard urinary dipstick from a patient with diabetes mellitus type 2 can be used to predict the estimated glomerular filtration rate (eGFR). We designed a multilayer perceptron (MLP) to investigate the possibility and optimal number of variables for the prediction. Methods: A total of 299 volunteers with diabetes mellitus type 2 were included. The blood and urine samples from volunteers were analyzed for blood sugar, glycated hemoglobin, serum creatinine, and urine chemistry. The urine chemistry was examined by a standard urinary dipstick. Volunteer age and gender and six test items of the dipstick were set as eight variables for this study. The eight variables were grouped and examined for the optimal combination. The eight variables from 232 of 299 volunteers were used to train an MLP for the optimal variables. The performance of trained MLP was validated by the data from 69 of 232 volunteers. Results: The optimal combination for variables was the six test items of the dipstick and volunteer age. The area under the curve (0.928), accuracy (0.879), sensitivity (0.83), and specificity (0.88) of the trained MLP were examined. Conclusions: The results demonstrate the eGFR prediction potential of the results of a urinary dipstick using this method.


2004 ◽  
Vol 89 (1) ◽  
pp. 61-70 ◽  
Author(s):  
Laura Maffei ◽  
Yoko Murata ◽  
Vincenzo Rochira ◽  
Gloria Tubert ◽  
Claudio Aranda ◽  
...  

We present the fourth case of an adult man (29 yr old) affected by aromatase deficiency resulting from a novel homozygous inactivating mutation of the CYP19 (P450arom) gene. At first observation, continuing linear growth, eunuchoid body proportions, diffuse bone pain, and bilateral cryptorchidism were observed. The patient presented also a complex dysmetabolic syndrome characterized by insulin resistance, diabetes mellitus type 2, acanthosis nigricans, liver steatohepatitis, and signs of precocious atherogenesis. The analysis of the effects induced by the successive treatment with high doses of testosterone, alendronate, and estradiol allows further insight into the roles of androgens and estrogens on several metabolic functions. High doses of testosterone treatment resulted in a severe imbalance in the estradiol to testosterone ratio together with the occurrence of insulin resistance and diabetes mellitus type 2. Estrogen treatment resulted in an improvement of acanthosis nigricans, insulin resistance, and liver steatohepatitis, coupled with a better glycemic control and the disappearance of two carotid plaques. Furthermore, the study confirms previous data concerning the key role of estrogens on male bone maturation, at least in part, and regulation of gonadotropin secretion. The biopsy of the testis showed a pattern of total germ cell depletion that might be due to the concomitant presence of bilateral cryptorchidism. Thus, a possible role of estrogen in male reproductive function is suggested but without revealing a direct cause-effect relationship. Data from this case provide new insights into the role of estrogens in glucose, lipid, and liver metabolism in men. This new case of aromatase deficiency confirms previous data on bone maturation and mineralization, and it reveals a high risk for the precocious development of cardiovascular disease in young aromatase-deficient men.


2015 ◽  
Vol 14 (4) ◽  
pp. 19110-19116 ◽  
Author(s):  
L.M. Wollinger ◽  
S.M. Dal Bosco ◽  
C. Rempel ◽  
S.E.M. Almeida ◽  
D.B. Berlese ◽  
...  

Author(s):  
Asmaa M. Salih Almohaidi ◽  
Kebaa Ahmed Saeed

Diabetes mellitus type 2 [DMT2] is a disturbance of metabolism and complex diseases influenced by environmental, genetic agents, and linked with inflammation, happens when the pancreas either does not use the insulin as it should or the body does not make enough insulin, lead to insulin resistance [IR] alongside with gradual loss of ß-cell secretory ability. The aim of this study was to investigate the role of soluble L-selectin (sL-selectin) in diabetes mellitus type 2 patients in Iraqi Arabs patient. Study includes seventy six Iraqi Arabs patients (male and female) having newly diagnosed type 2 diabetes mellitus (T2DM), with Fifty three Iraqi Arabs healthy subjects matched in age, sex and ethnic group. Patients and healthy subjects were genotyped, by PCR-RFLP analysis, and mesure serum level of L-selectin by enzyme-linked immunosorbent assay (sandwich ELISA) test include 65 patients and 23 controls. The statistical analysis of serum level of sL-selectin in study groups showed that the mean of sL-selectin level high significantly increased in patients group (10.708±1.1007) compared to control group (7.055±0.767) respectively. Thus, our results suggest soluble L-selectin play a role in the development of DMT2 in Iraqi Arabs patients. Present results showed that genotype PS associated with increase the susceptibility of DMT2.


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