scholarly journals INTERMITTENT TINNITUS IN ADULTS: AN INSIGHT INTO COVERT HEARING LOSS

2021 ◽  
pp. 133-135
Author(s):  
Badariya M. ◽  
Madhavan B. ◽  
Afreen Najeeb C.H. ◽  
Pooja Surendran
Keyword(s):  
Hearing Loss ◽  
Auditory System ◽  
High Frequency ◽  
Outer Hair Cell ◽  
Rank Test ◽  
Basal Region ◽  
High Frequency Region ◽  
Hearing Sensitivity ◽  
Signed Rank Test ◽  
Peripheral Auditory System

Objectives: Association of high frequency hearing loss/minor damage in peripheral auditory system in continuous chronic tinnitus with normal PTA is well established.The purpose of the study was to verify whether this finding is true for intermittent unilateral or bilateral tinnitus patients with normal PTA using EHF audiometry and conventional DPOAEs. Materials and method:This study was conducted on 45 normal hearing adults between the age ranges of 18-30 years. Among them 30 adults comprised of study group with intermittent tinnitus which varies in laterality.Tinnitus evaluation was done on these population followed by THI administration. DPOAE and EHF audiometry was completed on all subjects after conventional hearing assessment program. Result and Discussion:Kruskal Wallis H test & Wilcoxon signed rank test was used to compare OAE amplitude & EHF thresholds.Spearman's correlation was used to evaluate the correlation between DPOAE amplitude with EHF threshold. Reduced hearing sensitivity in the extended high frequency region may be early predictor of outer hair cell dysfunction in the most basal area.Findings of this study suggest that intermittent tinnitus may also lead to subtle lesion at the basal region of cochlea which would result in a significant hearing loss with continuous tinnitus in future. Conclusion:Intermittent tinnitus may increase the fragility of peripheral auditory system which may lead to permanent lesions and would be evident as elevated thresholds in conventional PTA.

Long-term outcome of children undergoing surgery for suspected perilymph fistula

2008 ◽  
Vol 123 (3) ◽  
pp. 298-302 ◽  
Author(s):  
R J Sim ◽  
A H Jardine ◽  
E J Beckenham
Keyword(s):  
Hearing Loss ◽  
Case Series ◽  
Outcome Data ◽  
Rank Test ◽  
Short Term ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Signed Rank ◽  
Signed Rank Test

AbstractA number of authors have suggested that surgery for suspected perilymph fistula is effective in preventing deterioration of hearing and in improving hearing in some cases in the short term. We present long-term hearing outcome data from 35 children who underwent exploration for presumed perilymph fistula at The Children's Hospital, Sydney, Australia, between 1985 and 1992.Methods:The pre-operative audiological data (mean of 500, 1000, 2000 and 4000 Hz results) were compared with the most recently available data (range two to 15 years) and the six-month post-operative data.Results:The short-term results showed no significant change in hearing at six months, with a subsequent, statistically significant progression of hearing loss in both operated and non-operated ears (Wilcoxon signed rank test: operated ear, p < 0.017; non-operated ear, p < 0.009).Conclusion:In this case series, exploratory surgery for correction of suspected perilymph fistula did not prevent progression of long-term hearing loss.

Caudal Pontine Reticular Formation of C57BL/6J Mice: Responses to Startle Stimuli, Inhibition by Tones, and Plasticity

1998 ◽  
Vol 79 (5) ◽  
pp. 2603-2614 ◽  
Author(s):  
Stephanie Carlson ◽  
James F. Willott
Keyword(s):  
Hearing Loss ◽  
Reticular Formation ◽  
Auditory System ◽  
Neural Plasticity ◽  
High Frequency ◽  
Acoustic Startle ◽  
Acoustic Startle Response ◽  
Pontine Reticular Formation ◽  
High Frequency Hearing Loss ◽  
Old Mice

Carlson, Stephanie and James F. Willott. Caudal pontine reticular formation of C57BL/6J mice: responses to startle stimuli, inhibition by tones, and plasticity. J. Neurophysiol. 79: 2603–2614, 1998. C57BL/6J (C57) mice were used to examine relationships between the behavioral acoustic startle response (ASR) and the responses of neurons in the caudal pontine reticular formation (PnC) in three contexts: 1) responses evoked by basic startle stimuli; 2) the prepulse inhibition (PPI) paradigm; and 3) the effects of high-frequency hearing loss and concomitant neural plasticity that occurs in middle-aged C57 mice. 1) Responses (evoked action potentials) of PnC neurons closely paralleled the ASR with respect to latency, threshold, and responses to rapidly presented stimuli. 2) “Neural PPI” (inhibition of responses evoked by a startle stimulus when preceded by a tone prepulse) was observed in all PnC neurons studied. 3) In PnC neurons of 6-mo-old mice with high-frequency (>20 kHz) hearing loss, neural PPI was enhanced with 12- and 4-kHz prepulses, as it is behaviorally. These are frequencies that have become “overrepresented” in the central auditory system of 6-mo-old C57 mice. Thus neural plasticity in the auditory system, induced by high-frequency hearing loss, is correlated with increased salience of the inhibiting tones in both behavioral and neural PPI paradigms.

Rate versus time representation of high-frequency spectral notches in the peripheral auditory system: A computational modeling study

2008 ◽  
Vol 71 (4-6) ◽  
pp. 693-703 ◽  
Author(s):  
Enrique A. Lopez-Poveda ◽  
Ana Alves-Pinto ◽  
Alan R. Palmer ◽  
Almudena Eustaquio-Martín
Keyword(s):  
Computational Modeling ◽  
Auditory System ◽  
High Frequency ◽  
Time Representation ◽  
System A ◽  
Rate Versus ◽  
Peripheral Auditory System ◽  
Modeling Study

Subclinical Congenital Cytomegalovirus Infection and Hearing Impairment

1974 ◽  
Vol 39 (3) ◽  
pp. 320-329 ◽  
Author(s):  
Arthur J. Dahle ◽  
Faye P. McCollister ◽  
Barbara A. Hamner ◽  
David W. Reynolds ◽  
Sergio Stagno
Keyword(s):  
Hearing Loss ◽  
Hearing Impairment ◽  
High Frequency ◽  
Cytomegalovirus Infection ◽  
Matched Control ◽  
Etiological Factor ◽  
Congenital Cytomegalovirus Infection ◽  
Congenital Cytomegalovirus ◽  
Hearing Sensitivity ◽  
Sensorineural Hearing Impairment

The hearing sensitivity of children with subclinical congenital cytomegalovirus infection was evaluated and compared with that of a group of matched control subjects. Nine of the 18 infected subjects had some hearing loss, ranging from slight high-frequency impairments to a severe-to-profound unilateral loss. The findings indicate that subclinical congenital cytomegalovirus must be considered a potential etiological factor in sensorineural hearing impairment.

scholarly journals Navigating Hereditary Hearing Loss: Pathology of the Inner Ear

2021 ◽  
Vol 15 ◽  
Author(s):  
Teresa Nicolson
Keyword(s):  
Hearing Loss ◽  
Animal Models ◽  
Inner Ear ◽  
Auditory System ◽  
Cranial Nerve ◽  
Hereditary Hearing Loss ◽  
Hearing Organ ◽  
Peripheral Auditory System ◽  
The Brain

Inherited forms of deafness account for a sizable portion of hearing loss among children and adult populations. Many patients with sensorineural deficits have pathological manifestations in the peripheral auditory system, the inner ear. Within the hearing organ, the cochlea, most of the genetic forms of hearing loss involve defects in sensory detection and to some extent, signaling to the brain via the auditory cranial nerve. This review focuses on peripheral forms of hereditary hearing loss and how these impairments can be studied in diverse animal models or patient-derived cells with the ultimate goal of using the knowledge gained to understand the underlying biology and treat hearing loss.

The Effects of High-Frequency Hearing Loss on Low-Frequency Components of the Click-Evoked Otoacoustic Emission

2003 ◽  
Vol 14 (09) ◽  
pp. 525-533 ◽  
Author(s):  
Owen D. Murnane ◽  
John K. Kelly
Keyword(s):  
Hearing Loss ◽  
High Frequency ◽  
Low Frequency ◽  
Otoacoustic Emission ◽  
Normal Hearing ◽  
Group Differences ◽  
Basal Region ◽  
Significant Group ◽  
High Frequency Hearing Loss ◽  
Frequency Components

Click-evoked otoacoustic emission (CEOAE) input/output (I/O) functions were measured in ears with normal hearing and in ears with sensorineural hearing loss above 2000 Hz. The low- to midfrequency CEOAEs obtained from the ears with high-frequency hearing loss were significantly reduced in level compared to the CEOAEs obtained from the ears with normal hearing even though there were no significant group differences in the 250–2000 Hz pure-tone thresholds. The findings are discussed within the context of two hypotheses that explain the low- to midfrequency reduction in transient-evoked otoacoustic emission (TEOAE) magnitude: (1) subclinical damage to the more apical regions of the cochlea not detected by behavioral audiometry, or (2) trauma to the basal region of the cochlea that affects the generation of low-frequency emissions. It is proposed that localized damage at basal cochlear sites affects the generation of low- to midfrequency CEOAE energy.

The Effect of Continuous Monaural Noise on Loudness Matches to Tinnitus

1988 ◽  
Vol 31 (1) ◽  
pp. 98-102 ◽  
Author(s):  
M. J. Penner
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Auditory System ◽  
Noise Level ◽  
Sensorineural Hearing ◽  
Peripheral Auditory System

Data from two psychophysical tasks are presented. In the first, 8 subjects with sensorineural hearing loss and tinnitus adjusted the intensity of a continuous monaural noise to mask the tinnitus. In the second, in the presence of continuous monaural noise, the same subjects adjusted the intensity of a pulsed monaural tone to match the loudness of the tinnitus. The tone was either ipsilateral or contralateral to the noise. Although the noise level required to mask the tinnitus increased substantially, as did the level of the ipsilateral matching tone, the change in the level of the contralateral matching tone was minimal. One possible explanation of these findings is related to the functioning of the peripheral auditory system.

scholarly journals Gender-Specific Associations of Speech-Frequency Hearing Loss, High-Frequency Hearing Loss, and Cognitive Impairment Among Older Community Dwellers in China

2021 ◽  
Author(s):  
Jingru Wang ◽  
Feng Wang ◽  
Peipei Han ◽  
Yuewen Liu ◽  
Weibo Ma ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Cognitive Impairment ◽  
Confidence Interval ◽  
High Frequency ◽  
Pure Tone ◽  
Community Dwelling ◽  
World Health ◽  
High Frequency Hearing Loss ◽  
Hearing Sensitivity ◽  
Community Dwellers

Abstract Objectives The purpose of this study was to investigate the relationship between speech-frequency hearing loss (SFHL), high-frequency hearing loss (HFHL), and cognitive impairment (CI). Then to determine whether there are any differences in gender among older community dwellers in China. Methods This study involved 1,012 adults aged ≥ 60 years (428 male; average age, 72.61 ± 5.51 years). The participants had their hearing and cognition measured using pure tone audiometry and Mini Mental State Examination (MMSE), respectively. We used the audiometric definition of hearing loss (HL) adopted by the World Health Organization (WHO). Speech-frequencies were measured as 0.5 kHz, 1 kHz, 2 kHz, and 4 kHz; high-frequencies were measured as 4 kHz and 8 kHz. Pure tone average (PTA) was measured as hearing sensitivity. Results Our studies demonstrated a 37.6% prevalence of HL in males and a 36.0% prevalence of HL in females. Adjusted for confounding variables, the results from a multivariate analysis showed that SFHL was associated with CI in females (OR = 2.400, 95% Confidence Interval = 1.313–4.385) and males (OR = 2.189, 95% Confidence Interval = 0.599–2.944). However, HFHL was associated with CI only in females (OR = 2.943, 95% Confidence Interval = 1.505–5.754). HL was associated with poorer cognitive scores (P < 0.05). “Registration” (P < 0.05) in MMSE was associated with speech- and high-frequency hearing sensitivity. Conclusion The associations between HL and CI varied according to gender in older community-dwellers, suggesting that different mechanisms are involved in the etiology of HL. Moreover, hearing sensitivity was negatively associated with cognition scores; therefore, early screening for HL and CI among older community-dwelling adults is advised.

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