scholarly journals Antimicrobial Drugs Susceptibility Pattern of Bacterial Pathogens Isolated from Cases of Tubotympanic Type of Chronic Suppurative Otitis Media (CSOM) in Tripoli-Libya

Author(s):  
 Khalled M Saeed ◽  
Nagat M Saeed ◽  
Fatma M Ben Rabha ◽  
Lamees Ben Saad ◽  
Samia A Hassan
2006 ◽  
Vol 21 (1-2) ◽  
pp. 20-23 ◽  
Author(s):  
Patricia N. Ayson ◽  
Jan Eero G. Lopez ◽  
Erasmo Gonzalo DV. Llanes

Objectives: To identify the bacterial pathogens associated with chronic suppurative otitis media and their antimicrobial sensitivity and resistance   Study Design: Cross-sectional survey   Setting: The study was carried out from July 2004-July 2005 at the outpatient clinic of a government tertiary hospital.   Number of subjects: A total of 32 patients (54 ears) with unilateral or bilateral active chronic suppurative otitis media.   Results: Bacterial pathogens of 54 ear discharge samples from CSOM were studied. Among them, 42 (78%) were pure cultures and 9 (16.7%) were mixed, only 3 (5.6%) of the submitted samples had no growth. There were 42 pure isolates, the most common of which was Staphylococcus aureus 21 (50%), followed by Pseudomonas aeruginosa 14 (33.3%). Drug sensitivity pattern of Staphylococcus aureus showed that 61.9% were resistant to Penicillin while more than 90% were sensitive to Aminoglycosides and Clindamycin. Pseudomonas aeruginosa was resistant to penicillin in 64.3% of cases and Ciprofloxacin was active against pseudomonas in 85.7%.   Conclusion: The most common bacterial pathogens from CSOM include Staphylococcus aureus and Pseudomonas aeruginosa. Majority of the isolates of Staphylococcus aureus were resistant to penicillin. Aminoglycosides, macrolides and quinolones were effective against most of the isolates of Staphylococcus aureus.   Keywords: chronic otitis media, perforated tympanic membrane, chronic aural discharge    


Author(s):  
Kiran Yadav ◽  
Sandeep Kaushik ◽  
Kumkum Rani ◽  
Anuj Kumar Tyagi

Introduction: Chronic Suppurative Otitis Media (CSOM) is a chronic and persistent inflammation of the mucosal lining of middle ear cleft which presents with recurrent ear discharge through a tympanic membrane perforation. CSOM is a worldwide disease and has higher prevalence in developing countries causing serious local damage and threatening complications. Aim: To determine the profile of CSOM, its causative agents and their antibiotic susceptibility pattern. Materials and Methods: The present study was a retrospective study in which data for culture and antimicrobial susceptibility profile of CSOM cases was retrieved from Microbiology department of Government Medical College, Kannauj, Uttar Pradesh, India, from January 2019 to October 2019 the analysis of data was done in February 2020. Two hundred pus swabs from discharging ears were processed during the study period for aerobic bacterial culture and antimicrobial susceptibility pattern in Microbiology department using standard microbiological techniques. The result analysis of the study was expressed as percentage and proportion for distribution of CSOM cases. Results: Out of 200 patients, 114 (57%) were males and 86 (43%) females. Among the 200 cases, 147 (73.5%) cases showed growth and 53 (26.5%) showed no growth. The most common organism isolated in this study was Pseudomonas aeruginosa, 67 (42.40%) followed by Staphylococcus aureus.48 (30.37%) and Klebsiella spp. 23 (14.55%). Gentamicin (85%) and amikacin (83%) had high level of antibacterial activity on all the isolates. Meropenem was found to be most effective drug for gram negative isolates. All Staphylococcus spp isolates were sensitive to vancomycin (100%). Conclusion:Pseudomonas aeruginosa was the most predominant organism isolated in otitis media patients. Most of the isolates were sensitive to meropenem.


2015 ◽  
Vol 16 (2) ◽  
pp. 79-82
Author(s):  
Metri C Basavaraj ◽  
P Jyothi

Introduction: Chronic suppurative otitis media (CSOM) remains one of the most common childhood chronic infectious diseases worldwide. It is recognized as an important cause of preventable hearing loss in the developing world. The present study was carried out to determine the etiological agent of CSOM and their antibiotic susceptibility pattern at the teaching hospital in North Karnataka.Methods: Samples were collected from patients in accordance with standard protocols. Organisms were identified by conventional microbiological techniques. Antibiotic susceptibility of the isolates was done by disc diffusion method according Clinical Laboratory Standards Institute (CLSI) guidelines.Results: A total of 159 patients were included in the study, out of which 53.5 % were males. Majority of the patients (85/159) were in the age group of 1-20 years. Pseudomonas was the most common organism causing CSOM, closely followed by Staphylococcus aureus. Pseudomonas were more sensitive to piperacilln-tazobactam (91%), followed by amikacin (80%). Among Staphylococcal isolates sensitivity was more to linezolid (93%), closely followed by piperacilln -tazobactam (88%). 73% of the Gram negative bacilli were sensitive to amikacin and 67% to gentamicinConclusion: Due to the easy availability and widespread use of antibiotics the susceptibility pattern of the pathogenic microorganisms are changing, therefore it is imperative to know the local susceptibility pattern of the causative agents, to treat the infection effectively.J MEDICINE July 2015; 16 (2) : 79-82


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