Dry eye disease and pterygium

Pterygium is a common external eye disease in general population which progresses slow but has a little effect on vision. Purpose: To know the tear film and ocular surface changes with pterygium. Study Design:A descriptive cross sectional study Place and duration of study: Federal Government Services Hospital Islamabad during Jun.2013 to Dec. Material and methods:Dry eye questionnaire (DEQ-6) was administered by a trained researcher and DE tests were performed in all 256 willing subjects (136 with pterygium+120control) age 30-76years,by a single surgeon under same physical conditions after taking the consent and approval from Hospital Ethical committee. Diagnosis was made on presence of both symptoms and tear film parameters. Statistical analysis was by simple percentages. Results:DE was found in 73(53.7%) of the pterygium cases and 28(23.5%) of the normal patients. In this study, 55(40.5%) were symptomatic, defined as reporting 1 or more DE symptoms often or all of the time. 53(39%) showed corneal fluorescein staining CFS and 69(51%) showed lid plugging/mucous threads in both groups Of 136 eyes with pterygium, [male 91 (67%) female 45(33%)], 50(37.5%) showed normal tear film and 86(62.5%) showed deranged functions whereas among 120 control eyes,[Male 73(61%) female 47(39%)],86(72.3%) were normal and 34(27.7%)had abnormal functions.These values were reduced indicating changed tear film in these patients. Conclusion:Pterygium disturbs tear functions causing dry eye like symptoms. Key-words: Dry eye, pterygium, tear film instability, ocular surface

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Dry Eye Disease and Pterygium

Pakistan Journal of Ophthalmology ◽

10.36351/pjo.v35i3.969 ◽

2019 ◽

Vol 35 (3) ◽

Author(s):

Munir Baig Rabeeya Munir

Keyword(s):

Dry Eye ◽

Ocular Surface ◽

Tear Film ◽

Cross Sectional Study ◽

Eye Disease ◽

Sectional Study ◽

Cross Sectional ◽

Dry Eyes ◽

Physical Conditions ◽

Film Instability

Purpose: To find the changes in tear film and ocular surface in patients with pterygium. Study Design: A descriptive cross sectional study. Place and Duration of Study: Federal Government Services Hospital Islamabad during June 2013 to December 2014. Material and Methods: Dry eye questionnaire (DEQ-6) was administered by a trained researcher and DE tests were performed in all 256 willing subjects (136 with pterygium+120 control) age 30-76 years, by a single surgeon under same physical conditions after taking the consent and approval from Hospital Ethical committee. Diagnosis was made on presence of both symptoms and tear film parameters. Statistical analysis by simple percentages. Results: Dry eyes (DE) were found in 73 (53.7%) of the pterygium cases and 28 (23.5%) of the normal patients. In this study, 55 (40.5%) patients were symptomatic, defined as reporting 1 or more DE symptoms often or all the time. There were 53 (39%) patients that showed corneal fluorescein staining (CFS) and 69 (51%) showed plugging/mucous threads in both groups. Of 136 eyes with pterygium there were 91 (67%) males and 45 (33%) females. Out of these 50 (36.7%) patients showed normal tear film and 86 (63.2%) showed deranged functions. Moreover, among the 120 control eyes there were 73 (61%) males and 47 (39%)] females. Out of these 86 (72.3%) patients were normal and 34 (27.7%) had abnormal functions. These values were reduced indicating altered tear film in these patients. Conclusion: Pterygium disturbs tear functions causing dry eye like symptoms. Key Words: Dry eye, pterygium, tear film instability, ocular surface.

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“ASSESSMENT OF VISUAL DISPLAY TERMINAL USE AS A RISK FACTOR FOR PAEDIATRIC DRY EYE DISEASE” : A CROSS SECTIONAL STUDY

10.36106/ijsr/1016246 ◽

2021 ◽

pp. 55-58

Author(s):

Souvik Ganguly ◽

Sheuli Kumar ◽

Sambuddha Ghosh ◽

Debarshi Jana

Keyword(s):

Risk Factor ◽

Dry Eye ◽

Ocular Surface ◽

Visual Display ◽

Cross Sectional Study ◽

Eye Disease ◽

Sectional Study ◽

Outdoor Activity ◽

Cross Sectional ◽

Visual Display Terminal

Purpose: To assess Visual Display Terminal(VDT) exposure as a risk factor for paediatric Dry Eye Disease(DED). Methodology: In this cross sectional study, children(5-15 years) from both urban and rural regions with VDT(computer,smartphone,television) exposure(1-2,3-4,>=5hours) were enrolled. Dry eye evaluation was done using Ocular Surface Disease Index (OSDI) Questionnaire, Schirmer's without anesthesia, Fluorescein-Tear lm Break-up Time(F-TBUT) and corneal , conjunctival uorescein staining as per Tear Film and Ocular Surface Society(TFOS) Dry Eye Workshop II Guidelines 2017(DEWS II). DED diagnosis was based on OSDI grading(>=13) and objective tests(>=1 positive test). Results: 315 children exposed to VDTwere selected for the study. Burning sensation and redness were the most common symptoms. Prevalence of DED was observed to be 6.03%(19 children-38 eyes). Mean age and hours of VDT exposure was signicantly higher and hours of outdoor activity and sleep signicantly lower in DED children compared to NON DED children(p<.05). Urban elder children had highest DED prevalence rate of 13.19% .Prevalence of DED in children using VDTfor 1-2 hours was .74%,3-4 hours was 28.57%, and >=5 hours was 47.83% (p=<.001). Children with short hours of outdoor activity(<3hours) had DED prevalence of 24.62 % whereas children with longer outdoor activity(>=3 hours) showed 1.20% prevalence(p<.001). Children with less hours of sleep(<8hours) showed DED prevalence of 22.58% and those with longer hours(>=8 hours) of sleep had only 1.98% DED prevalence (p<.001). Conclusion: DED was found to be associated with elder age, longer hours of VDT exposure , short hours of outdoor activity and sleep in VDTexposed children.

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A Survey on How Ocular Surface Demodex Infestation Interactively Associates with Diabetes Mellitus and Dry Eye Disease

Acta Parasitologica ◽

10.1007/s11686-021-00382-8 ◽

2021 ◽

Author(s):

Chang Huang ◽

Shuze Chen ◽

Sheng Fu ◽

Yingli Li ◽

Zhenhao Li ◽

...

Keyword(s):

Diabetes Mellitus ◽

Dry Eye ◽

Ocular Surface ◽

Cross Sectional Study ◽

General Information ◽

Potential Interaction ◽

Dry Eye Disease ◽

Eye Disease ◽

Cross Sectional ◽

Demodex Infestation

Abstract Purpose Prevention of ocular surface (OS) Demodex infestation plays an important role in OS hygiene and variety of factors may be associated with it, in which diabetes mellitus (DM) or dry eye disease (DED) has caught the attention of most scholars. However, there has been no research on whether there was a potential interaction between DM and DED in the process of OS Demodex infestation. This cross-sectional study was implemented in Zhujiang Hospital of Southern Medical University. Methods Ophthalmologic interviews, questionnaires, and examinations were conducted. Factors including general information, DM status, dry eye condition, etc. were collected to study the correlation of DM and DED on OS Demodex infestation. Results After statistical analysis, we found that both DM (P < 0.001) and DED (P = 0.013 < 0.05) are closely associated with OS Demodex infestation. Compared with DED, DM has higher priority association with OS Demodex infestation, and patients with both diseases have a significant higher risk of OS Demodex infestation (R = 0.197, P < 0.001). Meanwhile, age (R = 0.299, P < 0.001) and hypertension (P < 0.05) were also correlated with OS Demodex infestation. Conclusion This study provides a new evidence-based basis for clinical prevention and management of OS Demodex infestation.

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PENGARUH EMISI DEBU SEMEN TERHADAP STATUS TEAR FILM MASYARAKAT DI SEKITAR PABRIK PT. SEMEN PADANG

Jurnal Kesehatan Andalas ◽

10.25077/jka.v6i3.753 ◽

2018 ◽

Vol 6 (3) ◽

pp. 654

Author(s):

Muhammad Syauqie ◽

Ardizal Rahman ◽

Getry Sukmawati

Keyword(s):

Dry Eye ◽

Tear Film ◽

Cross Sectional Study ◽

Dry Eye Syndrome ◽

Sectional Study ◽

Cross Sectional ◽

Break Up

Permukaan okular rentan terhadap efek iritatif dari debu semen tersebut karena epitel konyungtiva dan kornea hanya dilapisi oleh lapisan tipis tear film. Paparan debu semen jangka panjang menyebabkan terjadinya inflamasi subklinis kronik yang dapat mempengaruhi transdiferensiasi epitel konyungtiva dan densitas sel goblet yang kemudian dapat menyebabkan timbulnya gejala dry eye syndrome. Tujuan penelitian ini adalah menilai status tear film pada masyarakat yang terpapar emisi debu semen dibandingkan dengan masyarakat yang tidak terpapar. Penelitian ini berupa analytic cross sectional study pada dua populasi yaitu kelompok terpapar dan tidak terpapar emisi debu pabrik semen. Semua sampel penelitian dari dua populasi menjalani pemeriksaan pH tear film, Schirmer, Ferning dan Tear Break Up Time (TBUT). Hasil studi mendapatkan peningkatan nilai pH tear film yang bermakna pada penduduk di kelompok terpapar dengan p=0.001. Terdapat juga penurunan kualitas Ferning yang bermakna pada penduduk di kelompok terpapar yang didominasi tipe III dengan p=0.005 dan 0.029. Sedangkan hasil pemeriksaan Schirmer dan TBUT masih dalam batas normal dan tidak terdapat perbedaan yang bermakna antara kedua kelompok. Simpulan studi ini ialah erdapat peningkatan rerata nilai pH tear film dan penurunan kualitas lapisan musin tear film yang bermakna pada masyarakat yang terpapar emisi debu semen namun tidak didapatkan peningkatan kejadian dry eye yang bermakna.

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Dry eye, its clinical subtypes and associated factors in healthy pregnancy: A cross-sectional study

PLoS ONE ◽

10.1371/journal.pone.0258233 ◽

2021 ◽

Vol 16 (10) ◽

pp. e0258233

Author(s):

Kofi Asiedu ◽

Samuel Kyei ◽

Madison Adanusa ◽

Richard Kobina Dadzie Ephraim ◽

Stephen Animful ◽

...

Keyword(s):

Logistic Regression ◽

Pregnant Women ◽

Dry Eye ◽

Associated Factors ◽

Cross Sectional Study ◽

Dry Eye Disease ◽

Eye Disease ◽

Sectional Study ◽

Cross Sectional ◽

Evaporative Dry Eye

The study determined the frequency of dry eye, its clinical subtypes and risk factors among pregnant women. This study was a hospital-based cross-sectional study of pregnant women visiting the antenatal clinic of the University of Cape Coast hospital. Clinical dry eye tests were performed along with the administration of a symptom questionnaire. Frequencies, chi-square analysis and logistic regression analyses were conducted to determine the frequency of dry eye disease, its clinical subtypes and associated factors. The prevalence of dry eye disease among the cohort of pregnant women was 82/201 (40.8% 95% confidence interval 34.3%-47.3%). Among the 82 pregnant women with dry eye disease, the frequencies of the clinical subtypes of dry eye were: evaporative dry eye [15/82(18.3%; 95% CI, 12.2%–25.2%)], aqueous deficient dry eye [10/82(12.2.%; 95% CI, 7.3%–18.3)], mixed dry eye [6/82(7.3%; 95% CI, 3.7%–11.0%)], and unclassified dry eye [51/82(62.2%; 95% CI, 52.4%–72.0%)]. Binary logistic regression analysis showed that the following factors were not significantly associated with dry eye: age, BMI, lipid profile, prolactin level, testosterone level, ocular protection index and blink rate. Only gestational age was significantly associated with dry eye disease in pregnancy. In conclusion, the current study showed that dry eye disease occurs frequently in pregnant women ranging from the first to the third trimester and it is associated with increasing gestational age. The evaporative dry eye was more common compared to the aqueous deficient dry eye, but most dry eye could not be classified.

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The Value of Aqueous Assessment in Diagnosing Dry Eye

IIUM Medical Journal Malaysia ◽

10.31436/imjm.v16i1.1188 ◽

2017 ◽

Vol 16 (1) ◽

Author(s):

Mohd Hafidz Ithnin ◽

Azrin Esmady Ariffin ◽

Khairidzan Mohd Kama

Keyword(s):

Dry Eye ◽

Clinical Signs ◽

Tear Film ◽

Cross Sectional Study ◽

Sectional Study ◽

Schirmer Test ◽

Cross Sectional ◽

Tear Meniscus ◽

Tear Meniscus Height ◽

Definition Of

Introduction: The clinical evaluation of the three layers of tear film is still poorly described. The purpose of this study is to evaluate the value of aqueous assessment in diagnosing dry eye. Materials and method: Schirmer test with anaesthesia (STA) and tear meniscus height (TMH) measurement were conducted on non-dry eye (NDE) and dry eye (DE) subjects in this cross-sectional study. The NDE and DE subjects were classified using two types of classification; classification 1 and classification 2. Results: 321 subjects with 642 eyes were recruited in the study. STA was significantly correlated with TMH (r = 0.24, p < 0.001) in all 642 eyes. The comparison between nondry and dry eye subjects in STA and TMH were not significantly different (p > 0.05) if the Classification 1 was used to define dry eye. In Classification 2, there were significantly different between NDE (12.5 ± 8.2 mm) and DE (3.4 ± 0.8 mm) subjects in STA (p < 0.001). Similar trend was also depicted in TMH based on the definition of dry eye stated in Classification 2 (NDE = 0.45 ± 0.20 mm, DE = 0.39 ± 0.14 mm; p < 0.05). Conclusion: The value of STA and TMH were lower significantly in dry eye subjects. However, the significant outcomes were only demonstrated if the clinical signs of dryness were used in the definition of dry eye.

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PENGARUH EMISI DEBU SEMEN TERHADAP PERMUKAAN OKULAR PADA MASYARAKAT DI SEKITAR PABRIK PT. SEMEN PADANG

Majalah Kedokteran Andalas ◽

10.25077/mka.v43.i2.p112-123.2020 ◽

2020 ◽

Vol 43 (2) ◽

pp. 112

Author(s):

Muhammad Syauqie

Keyword(s):

Dry Eye ◽

Tear Film ◽

Cross Sectional Study ◽

Dry Eye Syndrome ◽

Sectional Study ◽

Cross Sectional ◽

Break Up

Industri semen diketahui menghasilkan polutan udara yang berbahaya bagi kesehatan yang dapat berupa debu dan memiliki tingkat toksisitas yang paling tinggi dibanding polutan udara lainnya. Paparan debu semen jangka panjang menyebabkan terjadinya inflamasi subklinis kronik yang dapat mempengaruhi transdiferensiasi epitel konyungtiva dan densitas sel goblet yang kemudian dapat menyebabkan timbulnya gejala dry eye syndrome. Penelitian ini berupa analytic cross sectional study pada dua populasi yaitu kelompok terpapar dan tidak terpapar emisi debu pabrik semen. Semua sampel penelitian dari dua populasi menjalani pemeriksaan pH tear film, Schirmer, Ferning dan tear break up time.Terdapat peningkatan nilai pH tear film yang bermakna pada penduduk di kelompok terpapar Terdapat juga penurunan kualitas Ferning yang bermakna pada penduduk di kelompok terpapar yang didominasi tipe III. Sedangkan hasil pemeriksaan Schirmer dan TBUT masih dalam batas normal dan tidak terdapat perbedaan yang bermakna antara kedua kelompok. Pada pemeriksaan sitologi impresi pada kelompok terpapar didapatkan densitas sel goblet yang masih dalam batas normal dan juga tidak didapatkan metaplasia pada sel epitel konjungtiva. Terdapat peningkatan rerata nilai pH tear film dan penurunan kualitas lapisan musin tear film yang bermakna pada masyarakat yang terpapar emisi debu semen namun tidak disertai kerusakan permukaan okular dan peningkatan kejadian dry eye yang bermakna.

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