scholarly journals Antimicrobial chemotherapy of patients with lymphadenitis and adenophlegmon of the maxillofacial region

2021 ◽  
Vol 19 (3) ◽  
pp. 200-206
Author(s):  
R. V. Ushakov ◽  
V. N. Tsarev ◽  
A. R. Ushakov ◽  
A. A. Labazanov
Keyword(s):  
Antimicrobial Chemotherapy ◽  
Maxillofacial Surgery ◽  
Anaerobic Bacteria ◽  
Beta Lactam ◽  
Maxillofacial Region ◽  
Treatment Regimens ◽  
Number Of Patients ◽  
Inflammatory Processes ◽  
Biochemical Identification

Relevance. Patients with maxillofacial lymphadenitis account for 3.09 % of the total number of hospitalized in specialized departments of maxillofacial surgery, and 5.7% of the number of patients with various inflammatory processes of the maxillofacial region.Aim. Microbiological substantiation of the algorithm of antimicrobial chemotherapy for lymphadenitis and adenophlegmon of the maxillofacial region.Materials and methods. The analysis of the results of microbiological studies and determination of the sensitivity of isolated microorganisms to antibiotics of the material from inflammatory foci in lymphadenitis and adenophlegmon of the maxillofacial region was carried out using a standard protocol of laboratory microbiological studies. Anaerobic bacteria were cultured in the HiAnaerobic System Mark III anaerostat, identification was carried out using Biochemical Identification Test Kits (Himedia Labs).Results. The results of determining the sensitivity of the main pathogens of limphadenitis and adenophlegmon to the most commonly used antibiotics: groups of beta- lactam drugs, macrolides, lincosamides, imidazoles, teracyclines and fluoroquinolones are presented. The priorities of prescribing different treatment regimens are determined, taking into account the international classification of antibiotics AWaRe, adopted by WHO in 2018.Conclusions. Recommended drugs of choice for various forms of lymphadenitis and adenoflegmon include combinations of amoxicillin with clavulanic acid, lincosamides (preferably clindamycin) and fluoroquinolones (ciprofloxacin), which should be combined with imidazoles in odontogenic limphadenitis and adenophlegmon (for example, tinidazole as part of the complex drug Tsifran ST).

scholarly journals Feature PSI in Patients with Pathology of the Maximum-Face Region

2020 ◽  
Vol 4 (6) ◽  
pp. 83-86
Keyword(s):  
Oral Surgery ◽  
Maxillofacial Surgery ◽  
Antibiotic Sensitivity ◽  
Underlying Disease ◽  
Oral And Maxillofacial Surgery ◽  
Maxillofacial Region ◽  
Women Studies ◽  
Face Region ◽  
Etiological Agents

Currently, there is an acute problem of nosocomial purulent-septic infection (PSI), aggravating the course of the underlying disease, increasing the length of stay in the surgical hospital.An analysis of 104 case histories of patients of the Department of Oral and Maxillofacial Surgery for 2016 was performed, among them 55.77% of men and 44.23% of women. Studies included bacteriological analysis of isolates and determination of the antibiotic sensitivity spectrum of the selected cultures.PSI are the most common complications in patients with pathologies of the maxillofacial region. The etiological agents of PSI in patients with pathologies of the maxillofacial region are mainly gram-positive microorganisms represented by genera. Staphylococcus and Streptococcus. For antibacterial therapy in the department of oral surgery for patients, it is rational to use preparations of the group cephalosporins, aminoglycosides and tetracyclines.

scholarly journals STATUS, PROBLEMS AND PROSPECTS OF DEVELOPMENT OF SPECIALIZED SURGICAL CARE FOR PATIENTS WITH MAXILLOFACIAL PATHOLOGY IN KAZAN AND WAYS OF THEIRSOLUTION

2019 ◽  
Vol 15 (3) ◽  
pp. 90-95 ◽  
Author(s):  
Саид Ксембаев ◽  
Said Ksembaev ◽  
Олег Иванов ◽  
Oleg Ivanov ◽  
Ольга Торгашова ◽  
...  
Keyword(s):  
Maxillofacial Surgery ◽  
Surgical Care ◽  
Medical Work ◽  
Maxillofacial Region ◽  
Clinical Hospital ◽  
Dental Clinics ◽  
Number Of Patients ◽  
Low Efficiency ◽  
Hospital Morbidity

Subject of the study: current state of the organization and provision of specialized care to patients with pathology of the maxillofacial region in Kazan, the problems of improving the quality of this type of medical care and their solutions. The purpose — is to study organization and provision of specialized surgical care to patients with pathology of the maxillofacial region based on the results of work the Department of maxillofacial surgery of the city clinical hospital No. 7 of Kazan. The volume and nature of the care provided in the conditions of the round-the-clock dental hospital are defined. To determine the factors that reduce the quality of specialized surgical care for patients by analyzing data from the medical records of hospitalized and outpatient patients over the past 3 years. Material and methods. Uses analytical and quantitative-qualitative methods of retrospective study of the main indicators of medical work of the Department of maxillofacial surgery of the Kazan city clinical hospital No. 7 and patient records for 2016-2018. Results. Based on the analysis of the results of specialized Department of maxillofacial surgery determined the evolution of the number of patients according to nosological groups for 3 years, assess the volume of aid, to change its structure in favor of increasing the volume of outpatient surgical care while maintaining the number and structure of hospital morbidity. The evaluation of low efficiency of interaction between dental clinics and hospital, organizational and methodological approaches to the provision of this type of care. Conclusion. Analysis of the data obtained in the course of the study revealed a number of problems in routing patients for urgent and planned indications, in providing assistance at the prehospital stage in dental clinics, in posthospital rehabilitation of patients.

scholarly journals ANALYSIS OF THE STRUCTURE OF SURGICAL DISEASES OF MAXILLOFACIAL REGION IN THE HOSPITALISATION OF CHILDREN AND ADULTS IN SOUTH URAL

2021 ◽  
Vol 17 (2) ◽  
pp. 89-95
Author(s):  
Larisa Latyushina ◽  
Aleksandr Alabygin ◽  
Aleksandr Nasonov ◽  
Natalia Mindely ◽  
Aleksandra Bobrysheva
Keyword(s):  
Health Care ◽  
Inflammatory Diseases ◽  
Maxillofacial Surgery ◽  
Age Groups ◽  
Analysis Data ◽  
Dental Service ◽  
Surgical Pathology ◽  
Maxillofacial Region ◽  
Number Of Patients ◽  
Chelyabinsk Region

The reforms carried out in the country in health care redefine the tasks and functions of health care management, including the dental service. In recent decades, there has been a clear tendency towards an increase in dental morbidity in Russia against the background of a decrease in its availability and the level of preventive work, primarily due to an increase in the volume of medical care. In connection with the increase in the segment of non-state dental clinics, a change in the structure of the network of medical and prophylactic institutions of a dental profile is registered, while an increase in the number of patients seeking dental care for the first time at the stage of the disease requiring treatment in inpatient conditions is revealed. The aim of the study was to study the structure of surgical pathology of the maxillofacial region in children and adults in the Chelyabinsk region. To solve this goal, a retrospective study of the incidence and structure of surgical diseases of the maxillofacial region was carried out in patients of all age groups who received inpatient treatment in specialized departments for the period from 2016 to 2020. In the course of the study, it was revealed that in the Chelyabinsk region there is a consistently high need to provide assistance to patients of different ages with surgical pathology of the maxillofacial region in hospitalization — both among adults (18883 people were treated for the 5-year period under study), and during the analysis. data of pediatric patients (from 873 to 1070 children were treated per year). The majority of adult patients undergoing treatment in the conditions of the departments of maxillofacial surgery were admitted on an emergency basis with inflammatory processes (most often diagnosed with odontogenic phlegmon (L03.2)) and traumatic lesions of the face and neck (the vast majority — patients with fractures of the lower jaw (S02.6)), then in descending order — neoplasms, deformities and congenital pathology of the maxillofacial region followed; in children, after inflammatory diseases, neoplasms of the orofacial zone were recorded, followed by congenital pathology and facial injuries.

scholarly journals Substantiation of Targeted Research on the Development of Diagnostic and Differential-Diagnostic Tests Used in Chronic Sialoadenitis. Literature review

2021 ◽  
Vol 6 (4) ◽  
pp. 22-27
Author(s):  
I. O. Pohodenko-Chudakova ◽  
◽  
Keyword(s):  
Differential Diagnosis ◽  
Salivary Glands ◽  
Diagnostic Tests ◽  
Maxillofacial Surgery ◽  
Diagnostic Errors ◽  
Infectious Agent ◽  
Stone Disease ◽  
Malignant Neoplasms ◽  
Number Of Patients ◽  
Inflammatory Processes

The last decades in maxillofacial surgery and surgical dentistry are marked by the fact that one of the most popular and frequently encountered research topics is the pathology of the salivary glands. Patients with this pathology make up 2.3-5.2% of the total number of persons hospitalized during the year in specialized inpatient departments. The spectrum of these diseases is wide and includes: malformations, traumatic injuries, inflammatory processes of both viral and bacterial nature, reactive dystrophic lesions, salivary stone disease, benign and malignant neoplasms. Sialoadenitis can occur in both acute and chronic forms. At the same time, the ways of penetration of the infectious agent were determined: hematogenic, lymphogenic, contact, intraductal. The most frequently diagnosed inflammatory pathology of the salivary glands is chronic sialoadenitis. The purpose of the study is to identify unsolved problems and determine the directions of further research based on the analysis of available domestic and foreign specialized literature on epidemiology, diagnosis and differential diagnosis of chronic sialoadenitis. Materials and methods. The analysis of specialized literature containing information on the epidemiology, diagnosis and differential diagnosis of chronic sialoadenitis was carried out. The article analyzes periodicals for the last 10 years, as well as basic manuals, monographs, and textbooks without a statute of limitations. The descriptive method is used for the analysis. Results and discussion. Chronic sialoadenitis and sialosis account for 42.0-54.4% of the total pathology of the salivary glands. This is due to: an increase in the number of neoplasms, including malignant ones both in the maxillofacial region and in the salivary glands; an increase in the number of patients with thyroid diseases who use radioactive iodine for therapeutic purposes, which also accumulates in the salivary glands, which causes the appearance of symptoms of xerostomia and sialoadenitis; a significant share of publications indicating the complexity of the differential diagnosis of chronic sialoadenitis and a large number of diagnostic errors. Conclusion. The presented material proves that the task of developing diagnostic and differential-diagnostic tests used in chronic sialoadenitis is socially significant and belongs to the category of priority and determines the need for its early effective solution. The development and implementation of new diagnostic and differential-diagnostic tests developed and scientifically based on the principles of evidence-based medicine, used in patients with chronic sialoadenitis, will reduce the number of complications, improve the quality of life of patients, and increase the level of specialized medical care to the population

scholarly journals Revisiting Electrochemical Biosensing in the 21st Century Society for Inflammatory Cytokines Involved in Autoimmune, Neurodegenerative, Cardiac, Viral and Cancer Diseases

Sensors ◽  
2020 ◽  
Vol 21 (1) ◽  
pp. 189
Author(s):  
Susana Campuzano ◽  
Paloma Yáñez-Sedeño ◽  
José Manuel Pingarrón
Keyword(s):  
Point Of Care ◽  
Low Cost ◽  
Accurate Determination ◽  
Test Time ◽  
Electrochemical Biosensing ◽  
Recent Developments ◽  
Inflammatory Processes ◽  
Human Skills ◽  
Cancer Diseases

The multifaceted key roles of cytokines in immunity and inflammatory processes have led to a high clinical interest for the determination of these biomolecules to be used as a tool in the diagnosis, prognosis, monitoring and treatment of several diseases of great current relevance (autoimmune, neurodegenerative, cardiac, viral and cancer diseases, hypercholesterolemia and diabetes). Therefore, the rapid and accurate determination of cytokine biomarkers in body fluids, cells and tissues has attracted considerable attention. However, many currently available techniques used for this purpose, although sensitive and selective, require expensive equipment and advanced human skills and do not meet the demands of today’s clinic in terms of test time, simplicity and point-of-care applicability. In the course of ongoing pursuit of new analytical methodologies, electrochemical biosensing is steadily gaining ground as a strategy suitable to develop simple, low-cost methods, with the ability for multiplexed and multiomics determinations in a short time and requiring a small amount of sample. This review article puts forward electrochemical biosensing methods reported in the last five years for the determination of cytokines, summarizes recent developments and trends through a comprehensive discussion of selected strategies, and highlights the challenges to solve in this field. Considering the key role demonstrated in the last years by different materials (with nano or micrometric size and with or without magnetic properties), in the design of analytical performance-enhanced electrochemical biosensing strategies, special attention is paid to the methods exploiting these approaches.

scholarly journals A Diagnosis of Maxillary Sinus Fracture with Cone-Beam CT: Case Report and Literature Review

2014 ◽  
Vol 7 (2) ◽  
pp. 85-91 ◽  
Author(s):  
Selmi Yardimci Yilmaz ◽  
Melda Misirlioglu ◽  
Mehmet Zahit Adisen
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Maxillary Sinus ◽  
Cone Beam Ct ◽  
Maxillofacial Surgery ◽  
Maxillofacial Trauma ◽  
Cone Beam ◽  
Maxillofacial Region ◽  
Emergency Center ◽  
Frontal Wall

The purpose of this article is to present the case of maxillofacial trauma patient with maxillary sinus fracture diagnosed with cone-beam computed tomography (CBCT) and to explore the applications of this technique in evaluating the maxillofacial region. A 23-year-old male patient attempted to our clinic who had an injury at midface with complaints of swelling, numbness. The patient was examined before in emergency center but any diagnosis was made about the maxillofacial trauma. The patient re-examined clinically and radiographically. A fracture on the frontal wall of maxillary sinus is determined with the aid of CBCT. The patient consulted with the department of maxillofacial surgery and it is decided that any surgical treatment was not necessary. The emerging technique CBCT would not be the primary choice of imaging maxillofacial trauma. Nevertheless, when advantages considered this imaging procedure could be the modality of choice according to the case.

IRRATIONAL USE OF MEDICINES IN MEDICAL ORGANIZATIONS OF THE VOLGA FEDERAL DISTRICT. (ON THE EXAMPLE OF THE PENZA REGIONAL CLINICAL HOSPITAL NAMED AFTER N. N. BURDENKO, WHEN PROVIDING SPECIALIZED CARE TO CHILDREN IN THE CONDITIONS OF THE ADULT DEPARTMENT OF ORAL AND MAXILLOFACIAL SURGERY)

2021 ◽  
pp. 168-175
Author(s):  
Lebedev M.V. ◽  
Abdullina Y.A. ◽  
Zakharova I.Y.
Keyword(s):  
Medical Care ◽  
Maxillofacial Surgery ◽  
Federal District ◽  
Oral And Maxillofacial Surgery ◽  
Medical Organization ◽  
Maxillofacial Region ◽  
Clinical Hospital ◽  
Specialized Care ◽  
Rational Therapy ◽  
Medical Histories

The issues of financing in a medical organization are one of the most relevant areas of healthcare in the Russian Federation. Providing departments with the necessary financial resources to provide effective and accessible medical care to the population is important for both the administration and doctors and nurses. In some regions of the Volga Federal District, the departments are combined (Penza, Saransk), that is, all types of medical care are provided to both adults and children in one place, which leads to a number of problems associated with the irrational use of medicines. One of these is the department of Maxillofacial Surgery of the N.N. Burdenko National Clinical Hospital, on the basis of which the disadvantages of using drugs for parenteral use are considered. The purpose of this work is an economic analysis of the effectiveness of the use of solutions for parenteral use in children on the basis of an adult medical organization. The materials of the study were data from patients ' medical histories, prescribing lists, invoices from the pharmacy organization, and data on the cost of medicines. The results of the work are an analysis of the existing problems of combined type departments related to drug provision, a number of medicines for parenteral use that are not available to order, but are included in the standards of treatment of children with injuries of the maxillofacial region. The ABC - analysis of expenses under the item "medicines" is calculated, the data of the VEN – analysis is presented, which includes vital, necessary and secondary medicines for the treatment of children with injuries of the maxillofacial region. An algorithm for the selection of effective and rational therapy has been developed, using the example of antibacterial agents for parenteral administration.

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