THE EFFECTIVENESS OF CORRECTION OF ACUTE PAIN SYNDROME IN PATIENTS WITH OSTEOARTHRITIS WITH COMORBID PATHOLOGY IN THE CLINIC OF INTERNAL DISEASES

Author(s):  
Людмила Константиновна Пешехонова ◽  
Дмитрий Владимирович Пешехонов

Статья посвящена болевому суставному синдрому у больных остеоартритом в клинике внутренних болезней. Проблема лечения остеоартрита обусловлена болевым суставным синдромом, снижением качества жизни, ограничением социальной активности и нетрудоспособностью, что является актуальным в клинике внутренних болезней. Наибольшее влияние на качество жизни пациентов с остеоартритом оказывает частота, тяжесть и длительность обострений суставного синдрома. Особую сложность представляют коморбидные или полиморбидные пациенты, проведение которым традиционного лечения нередко становится невозможным из-за осложнений. Целью проведенного исследования стала сравнительная оценка купирования острого болевого суставного синдрома. Было доказано преимущество препарата амбениум парентерал, действующим веществом которого является фенилбутазон натрия в дозе 400 мг при однократном введении. Для решения данной проблемы был предложен оригинальный подход: на фоне традиционной терапии купирования болевого синдрома при остеоартрите, в группе наблюдения вводился амбениум парентерал после отмены назначаемых ранее НПВП в день введения. Инструментальная диагностика осуществлялась рентгенологическим, магнитно-резонансным и методом компьютерной томографии. Согласно шкале Лекена отмечалась эффективность назначения амбениум парентерал для уменьшения боли и дискомфорта, оптимизации дистанций ходьбы, а при использовании индекса WOMAC доказана достоверность повышения повседневной активности. Актуальным при проведении исследования было изучение качества жизни по шкале EQ-5D с выраженной оптимизацией субшкал при включении в схему лечения остеоартрита амбениум парентерал. Многоаспектный опросник KOOS доказал приоритет амбениум парентерал по коррекции сложности выполнения бытовых повседневных движений и спортивной активности на отдыхе. Нежелательные побочные эффекты у больных коморбидными заболеваниями были редкими. амбениум парентерал был не только высоко эффективен для лечения острого болевого суставного синдрома, но и хорошо переносился. Проведенное исследование позволяет рекомендовать АМБЕНИУМ парентерал для лечения остеоартрита у больных с коморбидными состояниями The article is devoted to the pain joint syndrome in patients with ostearthritis in the clinic of internal diseases. The problem of treating osteoarthritis is caused by a painful joint syndrome, a decrease in the quality of life, limited social activity and disability, which is relevant in the clinic of internal diseases. The frequency, severity and duration of exacerbations of the articular syndrome have the greatest impact on the quality of life of patients with osteoarthritis. Comorbid or polymorbid patients are particularly difficult, for whom traditional treatment often becomes impossible due to complications. The purpose of the study was a comparative assessment of the relief of acute joint pain syndrome. The advantage of the drug AMBENIUM parenteral, the active ingredient of which is sodium phenylbutazone at a dose of 400 mg with a single administration, has been proven. To solve this problem, an original approach was proposed: against the background of traditional therapy for pain relief in osteoarthritis, AMBENIUM parenteral was administered in the observation group after the withdrawal of previously prescribed NSAIDs on the day of administration. Instrumental diagnostics was carried out by X-ray, magnetic resonance and computed tomography. According to the Leken scale, the effectiveness of AMBENIUM parenteral was noted for reducing pain and discomfort, optimizing walking distances, and when using the WOMAC index, the reliability of increasing daily activity was proven. The study of the quality of life on the EQ-5D scale with a pronounced optimization of subscales when including AMBENIUM parenteral in the treatment regimen for osteoarthritis was relevant during the study. The multidimensional KOOS questionnaire proved the priority of AMBENIUM parenteral in correcting the complexity of performing everyday everyday movements and sports activity on vacation. Undesirable side effects in patients with comorbid diseases were rare. AMBENIUM parenteral was not only highly effective for the treatment of acute joint pain syndrome, but also well tolerated. The study allows us to recommend AMBENIUM parenteral for the treatment of osteoarthritis in patients with comorbid conditions

Author(s):  
Uma Phalswal ◽  
Vandna Pandey ◽  
Ashok Kumar ◽  
Abhay Elhence

<p class="abstract"><strong>Background:</strong> Knee osteoarthritis (OA) is a most common rheumatological disorder that causes functional limitation and disability. The most common problem in knee OA are joint pain and stiffness. It will lead to decreased quality of life and it have a serious economic burden on any country due to effect of disability and treatment.</p><p class="abstract"><strong>Methods:</strong> A correlational study was conducted to find out correlation between Ahlback grading and knee society score (KSS) on a sample of 100 moderate to severe knee OA patients and 142 OA knees. Data was collected at orthopedics OPD, for a period of 3 months by purposive sampling.</p><p class="abstract"><strong>Results:</strong> On evaluation, mean age of the participants was 60.19±1.01. Out of 100 patients, 42 patients had bilateral knee OA, therefore total 142 knees included in the analysis. More than half (51%) participants were overweight. Only 34% subjects had compliament to physiotherapy. Around 76% subjects taking analgesics and massage therapy to reduce knee pain. Maximum 82.4% subjects had a poor knee condition in KSS and mean score is 49.07±1.06. Ahlback grading in X-ray had negative correlation -0.610 with KSS. Hence it is evaluated, both the scales have approximately same result as it is analyzed that both scales are moderately correlated. There is significant association of age, occupation and physiotherapy with Ahlback grading followed with KSS significant associated with BMI, occupation and physiotherapy.</p><p class="abstract"><strong>Conclusions:</strong> The study concluded that there is a moderate correlation found between Ahlback X-ray grading and knee society scoring. X-ray and knee society scoring (clinical evaluation) both are essential for effective treatment of OA.</p>


2020 ◽  
Vol 22 (12) ◽  
pp. 84-88
Author(s):  
Svetlana E. Dymnova ◽  
◽  
Svetlana E. Dymnova ◽  
Vera V. Sergeeva ◽  
◽  
...  

Osteoporosis is one of the most common metabolic diseases of the skeleton that develops with age. Close attention to osteoporosis is explained by its high pre-valence, as well as often severe medical, social and economic consequences, in the form of fractures of the vertebrae and peripheral bones, which lead not only to disability, but also high mortality, especially among elderly patients. To date, there is no unified and clear method of treatment and rehabilitation of patients of older age groups, taking into account their clinical and functional characteristics against the background of concomitant diseases. As a result, many patients do not receive the treatment they need, or the effect of treatment is often lower than expected. Aim. To analyse of clinical and functional characteristics, quality of life and the main directions of rehabilitation of elderly patients with osteoporosis in combination with concomitant pathology in the form of impaired carbohydrate metabolism. Materials and methods. The study included 188 elderly patients diagnosed with osteoporosis. The control methods were general clinical examination, ECG and 24-hour ECG monitoring, ECHO CG, analysis of BMD using dual-energy X-ray absorptiometry – densitometry (dualenergy X-ray absorbtiometry – DXA). Assessment of the degree of development of the atherosclerotic process by ultrasonic duplex scanning (USDS). In order to determine the structural and functional state of the abdominal organs, all patients underwent ultrasound examination. All patients were examined by related specialists: an ophthalmologist, neurologist, cardiologist. To diagnose diabetic neuropathy, the following diagnostic scales were used: the Neuropathy Symptom Score (NSS). The quality of life (QOL) of pa-tients was assessed using the MOS SF-36 questionnaire (modified version for Russia). Results. The features of the clinical picture of osteoporosis, complicated and not complicated by pathological fractures of various localization, are highlighted, taking into account the age characteristics of patients and the influence of concomitant pathology. Difficulties in the treatment and rehabilitation of patients with osteoprosis and its consequences, accompanied by limitation of physical activity, pain syndrome, psychoemotional disorders, resulting in a decrease in the quality of life, are described. Conclusion. Modern methods of treatment and rehabilitation provide great opportunities for restoring working capacity and significantly improving the quality of life in patients with osteoporosis and its consequences. However, existing programs of treatment and rehabilitation should be developed individually, taking into account age, severity of structural and functional disorders, as well as the presence and severity of concomitant diseases.


2020 ◽  
Vol 96 (2) ◽  
pp. 24-28
Author(s):  
T.V. Buylova ◽  
V.A. Balchugov ◽  
E.A. Severova

The aim of the study was to estimate rehabilitation efficiency in the sportsmen and physical culture professionals with a shoulder pain syndrome. Materials and methods: 980 patients with a shoulder pain syndrome undergo rehabilitation treatment. The reasons of acute or chronic shoulder pain syndrome were: acute trauma (7% of cases) or chronic microtraumatization (93% of cases) of shoulder tissues during the physical culture activities and sport. Rotary cuff pathology was diagnosed in 88% of patients, long head of biceps pathology - in 5%, acromioclavicular joint pathology - in 4%, the subacromial bursitis in 2% of cases, damage of the glenoid labrum (Bankarta) in 1%. Clinical methods (including the quality of life questionnaire -DASH) and instrumental methods (USD and MRI) were used. The differentiated rehabilitation programs (with the use of modern physical therapy methods) were recommended considering features of shoulder pathology, a patients clinical condition and their physical (including sports) activity. Results: Excellent and good results were stated in 98% of patients with a shoulder pain syndrome. 2% of patients were directed for the surgical intervention (rotary cuff and glenoid labrum restoration). Compensation of a shoulder pain syndrome was stated in 82% of patients; in 16% of patients the pain syndrome had significantly decreased. In 87% of patients function of the injured shoulder joint was restored, in 11% of patients - it significantly improved. Strength of shoulder muscles and a humeroscapular rhythm were restored and the quality of life (according to the DASH questionnaire) improved in 98% of patients. Conclusion. Use of the differentiated programs of rehabilitation using modern physical techniques allows to receive excellent and good results in all patients with a shoulder pain syndrome involved physical culture and sport.


2017 ◽  
Vol 17 (1) ◽  
pp. 22-29 ◽  
Author(s):  
Bo Nyström ◽  
Birgitta Gregebo ◽  
Adam Taube ◽  
Stig-Olof Almgren ◽  
Birgitta Schillberg ◽  
...  

AbstractBackgroundIt has been reported that in 13-32% of patients with chronic low back pain, the pain may originate in the sacroiliac (SI) joints. When treatment of these patients with analgesics and physiotherapy has failed, a surgical solution may be discussed. Results of such surgery are often based on small series, retrospective analyses or studies using a minimal invasive technique, frequently sponsored by manufacturers.PurposeTo report the clinical outcome concerning pain, function and quality of life following anterior arthrodesis in patients presumed to have SI joint pain using validated questionnaires pre- and post-operatively. An additional aim was to describe the symptoms of the patients included and the preoperative investigations performed.Material and methodsOver a 6 year period we treated 55 patients, all women, with a mean age of 45 years (range 28-65) and a mean pelvic pain duration of 9.1 years (range 2-30). The pain started in connection with minor trauma in seven patients, pregnancy in 20 and unspecified in 28. All patients had undergone long periods of treatment including physiotherapy, manipulation, needling, pelvic belt, massage and chiropractic without success, and 15 had been operated for various spinal diagnoses without improvement. The patients underwent thorough neurological investigation, plain X-ray and MRI of the spine and plain X-ray of the pelvis. They were investigated by seven clinical tests aimed at indicating pain from the SI joints. In addition, all patients underwent a percutaneous mechanical provocation test and extra-articular local anaesthetic blocks against the posterior part of the SI joints. Before surgery all patients answered the generic Short-Form-36 (SF-36) questionnaire, the disease specific Balanced Inventory for Spinal Disorders (BIS) questionnaire and rated their level of pelvic and leg pain (VAS, 0-100). At follow-up at a mean of 2 years 49 patients completed the same questionnaires (89%).ResultsAt follow-up 26 patients reported a lower level of pelvic pain than before surgery, 16 the same level and six a higher level. Applying Svensson’s method RPpelvic pain = 0.3976, with 95% CI (0.2211, 0.5740) revealed a statistically significant systematic improvement in pelvic pain. At follow-up 28 patients reported a higher quality of life and 26 reported sleeping better than pre-operatively. In most patients the character of the pelvic pain was dull and aching, often accompanied by a stabbing component in connection with sudden movements. Referred pain down the leg/s even to the feet and toes was noted by half of the patients and 29 experienced frequency of micturition.ConclusionsIt is apparent that in some patients the SI joints may cause long-term pain that can be treated by arthrodesis. We speculate that continued pain despite a healed arthrodesis may be due to persistent pain from adjacent ligaments. The next step should be a prospective randomized study comparing posterior fusion and ligament resection with non-surgical treatment.ImplicationsAnterior arthrodesis can apparently relieve pain in some patients with presumed SI joint pain. The problem is how to identify these patients within the low back pain group.


2007 ◽  
Vol 177 (4S) ◽  
pp. 31-31
Author(s):  
J. Curtis Nickel ◽  
Dean Tripp ◽  
Shannon Chuai ◽  
Mark S. Litwin ◽  
Mary McNaughton-Collins

Author(s):  
Yu. V. Antonova ◽  
A. M. Iskandarov ◽  
I. B. Mizonova

Introduction.Coccygodynia is a multidisciplinary disease which is diffi cult to treat. It seriously limits the ability to work and signifi cantly affects the quality of life of patients. The study of somatic dysfunctions in patients with coccygodynia and the analysis of the results of osteopathic treatment of such patients makes it possible to justify the necessity of osteopathic correction of coccygodynia.Goal of the study— to determine the structure of the leading somatic dysfunctions in patients with coccygodynia and to study the effectiveness of osteopathic treatment of this pathology.Materials and methods.The study involved 44 patients from 25 to 65 years old, randomly divided into two groups. The main group of 24 people (20 women and 4 men) received osteopathic treatment, in accordance with the identifi ed leading somatic dysfunctions. Patients of the control group (16 women and 4 men) were treated locally with soft manual techniques (the treatment area was limited by the pelvic region). In order to assess the results of the treatment, we examined the intensity of the pain syndrome and the psycho-emotional state of patients. The severity of the pain syndrome was assessed in accordance with the visual analogue scale (VAS). The psycho-emotional state (with physical and mental components) was assessed with the help of the SF-36 quality of life questionnaire.Results.Somatic dysfunctions typical for patients with coccygodynia have been identifi ed. Osteopathic treatment has proven to be more effective in comparison with local manual therapy of coccygodynia both in early periods and in 3 months after the end of the treatment course.Conclusion.Osteopathic treatment of post-traumatic coccygodynia is effective, and can be recommended for treatment of such patients.


Author(s):  
М.Р. Оразов ◽  
В.Е. Радзинский ◽  
М.Б. Хамошина ◽  
Е.Н. Носенко ◽  
Э.С. Токаева ◽  
...  

Цель исследования - изучение особенностей обмена гистамина при хронической тазовой боли у пациенток с наружным генитальным эндометриозом. Методика. В сыворотке крови 100 пациенток методом высокоточного (в нг/мл) иммуноферментного твердофазного анализа определяли концентрацию гистамина. Использованы реактивы «Histamine ЕLISA», аппарат BAE-1000 Гистамин (Labor Diagnostika Nord - LDN, Германия). Оценка выраженности болевого синдрома осуществлялась по шкале ВАШ, оценка качества жизни - на основании опросника для оценки качества жизни при эндометриозе (EHR-30), оценка тревожности - опросника Спилбергера-Ханина. Результаты. Показано статистически значимое повышение уровня гистамина у пациенток с высокой интенсивностью болевого синдрома. Женщины с наружным генитальным эндометриозом, сопровождающимся интенсивным болевым синдромом в 100% случаев обнаруживали высокие уровни ситуативной и личностной тревожности, тогда как, лишь у 40% женщин (n = 16) контрольной группы выявлен умеренный уровень тревожности. Депрессивные расстройства выявлены у 58,3% женщин с хронической тазовой болью (n = 35), из них основную часть (n = 20) составили женщины с выраженной степенью болевого синдрома по ВАШ. Заключение. Психоэмоциональное состояние женщин с тазовой болью, ассоциированной с наружным генитальным эндометриозом, характеризуется высокими уровнями депрессивных и тревожных расстройств, значительным снижением уровня качества жизни. Выявлена прямая связь между интенсивностью болевого синдрома и уровнем гистамина в периферической крови пациенток с наружным генитальным эндометриозом. Objective. To study features of histamine metabolism in patients with chronic pelvic pain associated with external genital endometriosis. Methods. For quantitative assessment of histamine level in peripheral blood was taken from 100 patients which than was centrifuged. In blood serum histamine concentration was determined by enzyme-linked immunosorbent assay method with reagents «Histamine ЕLISA» on the machine BAE-1000 Histamine (Labor Diagnostika Nord - LDN, Hermany). A pain syndrome was assessed by Visual Analog Scale (VAS), quality of life assessment - by Endometriosis Health Profile Questionnaire (EHR-30), level of anxiety was determined by Spielberger-Khanin questionnaire. The results. Showed statistically higher histamine level in patients with severe pain according to VAS. After assessment of results obtained from Spielberger-Khanin questionnaire 100% experimental group’s women with external genital endometriosis (n = 60) were noted to be have high level of state and trait anxiety, then 40% women of control group (n = 16) have moderate level of anxiety. The incidence of depression in women with chronic pelvic pain was 58.3% (n = 35) and the main part (n = 20) were women with severe stage of pelvic pain according to VAS. Conclusions. Psycho emotional condition of women with external genital endometriosis associated pelvic pain characterized by higher depression and anxiety levels, with significant decrease quality of life. Direct relationship also was found between pain syndrome intensity and histamine level in peripheral blood in patients with external genital endometriosis.


2015 ◽  
pp. 50-58
Author(s):  
Thi Dung Nguyen ◽  
Tam Vo

Background: The patients on hemodialysis have a significantly decreased quality of life. One of many problems which reduce the quality of life and increase the mortality in these patients is osteoporosis and osteoporosis associated fractures. Objectives: To assess the bone density of those on hemodialysis by dual energy X ray absorptiometry and to examine the risk factors of bone density reduction in these patients. Patients and Method: This is a cross-sectional study, including 93 patients on chronic hemodialysis at the department of Hemodialysis at Cho Ray Hospital. Results: Mean bone densities at the region of interest (ROI) neck, trochanter, Ward triangle, intertrochanter and total neck are 0.603 ± 0.105; 0.583 ± 0.121; 0.811 ± 0.166; 0.489 ± 0.146; 0.723 ± 0.138 g/cm2 respectively. The prevalences of osteoporosis at those ROI are 39.8%, 15.1%; 28%; 38.7%; and 26.9% respectively. The prevalences of osteopenia at those ROI are 54.8%; 46.3%; 60.2%; 45.2% and 62.7% respectively. The prevalence of osteopososis in at least one ROI is 52.7% and the prevalence of osteopenia in at least one ROI is 47.3%. There are relations between the bone density at the neck and the gender of the patient and the albuminemia. Bone density at the trochanter is influenced by gender, albuminemia, calcemia and phosphoremia. Bone density at the intertrochanter is affected by the gender. Bone density at the Ward triangle is influenced by age and albuminemia. Total neck bone density is influenced by gender, albuminemia and phosphoremia. Conclusion: Osteoporosis in patients on chronic hemodialysis is an issue that requires our attention. There are many interventionable risk factors of bone density decrease in these patients. Key words: Osteoporosis, DEXA, chronic renal failure, chronic hemodialysis


2021 ◽  
Vol 41 (01) ◽  
pp. 067-074
Author(s):  
Seoyon Yang ◽  
Min Cheol Chang

AbstractPain is common but often underrecognized after stroke. Poststroke pain (PSP) hinders recovery, impairs quality of life, and is associated with the psychological state of patients with stroke. The most common subtypes of PSP include central PSP, complex regional pain syndrome, shoulder pain, spasticity-related pain, and headache. The pathophysiologies of these PSP subtypes are not yet clearly understood, and PSP is refractory to conventional treatment in many patients. However, recent studies have proposed potential pathophysiologies of PSP subtypes, which may help prioritize therapies that target specific mechanisms.


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