scholarly journals Effectiveness of Levonorgestrel - Releasing Intrauterine System in Perimenopausal Bleeding

2019 ◽  
Vol 70 (1) ◽  
pp. 211-214
Author(s):  
Flavius Olaru ◽  
Constantin Olaru ◽  
Viviana Olaru ◽  
Laura Nussbaum ◽  
Lavinia Hogea ◽  
...  

The study aimed to compare the effectiveness of conservative methods [Levonorgestrel (C21H28O2) � releasing intrauterine system (52 mg), endometrial ablation, hysteroscopy] vs. hysterectomy in perimenopausal bleeding. The study population was represented by 270 women addressed to Genesiun Clinic between 2010-2018 for perimenopausal bleeding because of different pathological circumstances: endometrial hypertrophy, polyps, uterine fibroids, endocervical lesions, chronic endometritis, intrauterine device (IUD)-related pathology, congenital abnormalities. The hysteroscopy is considered the method of choice in the diagnosis/therapeutic management of hemorrhagic metropathy. The hysteroscopic surgery was superior to hysterectomy, taking into account the postoperative complications and recovery, resumption of sexual activity and working. Levonorgestrel-releasing IUS 52 mg proved safe and efficient in treating metrorrhagia associated with endometrial dysplasia, uterine fibroids, and polyps. The bipolar electrosurgical VERSAPOINT system demonstrated good results in the treatment of intrauterine pathology. Our results pointed out the alternative of a surgery a few months after the hysteroscopy and endometrial ablation, and also the possibility of repeating the hysteroscopy procedure after a while, in some cases.

Author(s):  
R. Uma Rani

The udder is a very important organ and has economic value in dairy cattle. Though highly vulnerable to various disease conditions, e.g. mastitis, congenital anomalies in the udder are of rare occurrence (Dandale et al., 2013). Congenital abnormalities of the mammary system in cows comprise absence of teats, glands, supernumerary teats and imperforate teats. Absence of teat is extremely rare, but isolated cases in which the teats were only represented by slight eminences have been met with (O’ Connor, 1980). Athelia was reported in buffaloes by Sailendra and Sandhya (1998) and Vidyasagar (2009) and in a Japanese black heifer by Ghanem et al. (2011). In the present paper, a rare case of athelia in a Jersey crossbred cow and its therapeutic management by permanent cessation of lactation is reported.


2007 ◽  
Vol 26 (7) ◽  
pp. 941-946 ◽  
Author(s):  
Riko Tamura-Sadamori ◽  
Makoto Emoto ◽  
Yasuko Naganuma ◽  
Toru Hachisuga ◽  
Tatsuhiko Kawarabayashi

2018 ◽  
Vol 27 (10) ◽  
pp. 1204-1214 ◽  
Author(s):  
Matthew R. Davis ◽  
Ahmed M. Soliman ◽  
Jane Castelli-Haley ◽  
Michael C. Snabes ◽  
Eric S. Surrey

2017 ◽  
Vol 2 (2) ◽  
pp. 69
Author(s):  
Anita Nugrahaeni ◽  
Muchlis Achsan Udji Sofro ◽  
Zahroh Shaluhiyah ◽  
Antono Suryosaputro ◽  
Bagoes Widjanarko

Background : Gonorrhoea is a health problem with increasing rates worldwide. The phenomena of increasing and spreading gonorrhoea cases affect the high risk groups including Indirect Female Sex Workers (IFSWs). The aim of this study was to explain some host factors as the risk factors of gonorrhoea in IFSWs in Wonosobo.Methods : This is an observational research with control case design. The study population was IFSWs who worked as lady companions in karaoke under the guidance of NGO Wonosobo Youth Center and had done the STI examination by STI clinic. The subjects were 84 consist of 42 case and 42 control. Samples were collected by consecutive sampling technique. Data analysis used chi-square, Odd Ratio (OR) and logistic regression.Results : Influencing factors to the occurence of gonorrhoea in IFSWs were history ofcombination sexual activity (p=0,013; OR=3,843; 95% CI= 1,323-11,63), history of STI (p=0,013; OR=3,863; 95% CI= 1,328-11,240), and consistency of condom use (p=0,009; OR=5,778; 95% CI=1,553-21,491).Conclusion : Factors that had been proven to influence the occurence of gonorrhoea in ISFWs were history of combination sexual activity, history of STI, and consistency of condom use.


2022 ◽  
Vol 20 (1) ◽  
Author(s):  
Zhihui Gao ◽  
Jie Wang ◽  
Sheng Shen ◽  
Xiaobo Bo ◽  
Tao Suo ◽  
...  

Abstract Background The efficacy of preoperative biliary drainage (PBD) has been debated for several decades, and yet indications for PBD remain controversial. The aim of this study was to compare the postoperative morbidity and mortality in patients with malignant obstructive jaundice undergoing direct surgery versus surgery with PBD. Methods All consecutive patients with malignant obstructive jaundice who underwent radical resection between June 2017 and December 2019 at Zhongshan Hospital were analyzed retrospectively. The study population was divided into two groups: PBD group (PG) and direct surgery group (DG). The subgroups were chosen based on the site of obstruction. Perioperative indicators and postoperative complications were compared and analyzed. Results A total of 290 patients were analyzed. Postoperative complications occurred in 134 patients (46.4%). Patients in the PG group had a lower overall rate of postoperative complications compared with the DG group, with perioperative total bilirubin (TB) identified as an independent risk factor in multivariate analysis (hazard ratio = 1.004; 95% confidence interval 1.001–1.007; P = 0.017). Subgroup analysis showed that PBD reduced the complication rate in patients with proximal obstruction. In the proximal-obstruction subgroup, a preoperative TB level > 162 μmol/L predicted postoperative complications. Conclusions PBD may reduce the overall rate of postoperative complications among patients with proximal malignant obstructive jaundice. Trial registration ClinicalTrials.gov, 2018ZSLC 24. Registered May 17, 2018, https://clinicaltrials.gov/.


2017 ◽  
Vol 27 (9) ◽  
pp. 1919-1925 ◽  
Author(s):  
Fangfang Wang ◽  
Aijun Yu ◽  
Haichao Xu ◽  
Xiaojing Zhang ◽  
Li Li ◽  
...  

ObjectiveThis study aims to explore the feasibility of a hysteroscopic procedure combined with progestin therapy in young patients with stage Ia endometrioid carcinoma (EC) to avoid sterilization.Materials and MethodsEleven young women with stage Ia EC (International Federation of Gynecology and Obstetrics grade 1) who were treated with a hysteroscopic approach combined with progestin from July 2004 to June 2016 were retrospectively analyzed and followed up to monitor their general recovery and pregnancy outcome.ResultsThe patients' median age was 27.3 years (range, 25–39 years). Comorbidities consisted of primary infertility in 8 patients, polycystic ovary syndrome in 4, uterine fibroids in 2, and diabetes in 1. The results of immunohistochemical analysis were positive for all estrogen and progestin receptors. After treatment, 9 patients attained complete remission, and 2 patients achieved partial remission. The results of peritoneal cytology in 4 patients were negative. As of this writing, 6 of the 11 patients have given birth to 7 infants, and 1 patient had an ectopic pregnancy. Two patients ultimately underwent radical resection. The average follow-up time was 82.3 months (range, 15 to 152 months), and all patients remain disease-free.ConclusionsHysteroscopic surgery combined with progestin treatment for stage Ia EC in young patients to avoid sterilization was practical and may represent a new option for patients with stage Ia EC who wish to preserve their fertility.


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