scholarly journals Differential Diagnosis in Esophageal Cancer. Review on literature

2019 ◽  
Vol 70 (1) ◽  
pp. 331-335
Author(s):  
Cristian Constantin Popa ◽  
Dumitru Cristinel Badiu ◽  
Liliana Florina Andronache ◽  
Radu Virgil Costea ◽  
Stefan Ilie Neagu ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Differential Diagnosis ◽  
Developed Countries ◽  
Point Of View ◽  
Esophageal Diseases ◽  
Anatomical Features ◽  
Cancer Review ◽  
Clinical Point ◽  
Very High ◽  
Made In

Esophageal cancer represents a neoplasm that is thought to have both an increased incidence and prevalence in the following years. Although much progress has been made in the detection and the early treatment of esophageal cancer, the prognosis is still limited, and mortality remains very high. The most common histological types of esophageal cancer are squamous cell carcinoma, and, respectively, adenocarcinoma. Lately, there has been an accelerated increase in the incidence of adenocarcinoma, in the context of increased prevalence of gastro-esophageal reflux disease and obesity, but also of the current alimentary diet, especially in developed countries. The esophagus has its anatomical features. Moreover, it is located topographicallyin a complex cervico-thoraco-abdominal area, unique for a viscus. From the clinical point of view, the onset of symptoms of esophageal cancer is insidious. For these reasons, special attention should be pain in the early detection and differentiation of this neoplasm from other pathologies. These pathologies are very varied and may comprise other esophageal diseases, neighborhood pathologies such as cervical, thoracic, abdominal, systemic pathologies (immunologic, infectious) or other pathologies such as the oro-maxillo-facial, oculo-orbital, vascular, muscular, and cutaneous ones. Keywords: esophagus, cancer, differential diagnosis

The prevalence of ethnocentric tendencies in Bangladesh

2015 ◽  
Vol 9 (1) ◽  
pp. 1-16 ◽  
Author(s):  
Tamgid Ahmed Chowdhury
Keyword(s):  
Developed Countries ◽  
Consumer Products ◽  
Point Of View ◽  
Potential Threat ◽  
Content Type ◽  
Positive Attitudes ◽  
Rigorous Study ◽  
The Difference ◽  
The Developed Countries ◽  
Made In

Purpose – This paper aims to argue that the traditional belief that “consumer ethnocentrism is a phenomenon of the developed countries only” is no longer true. To establish this argument, our study assesses the applicability of the Consumer Ethnocentric Tendencies Scale (CETSCALE) in Bangladesh by judging the unidimensionality feature of the same. Design/methodology/approach – The methodology is based on sample of 788 respondents collected from 27 border and non-border districts of Bangladesh. Findings – Statistically significant results show that for the consumers of border and non-border districts, the original CETSCALE is, to a great extent, applicable as those groups have shown positive attitudes in retaining 12-14 items out of the 17 items of the original scale. However, the groups and the respondents as a whole did not agree with the unidimensionality feature of the CETSCALE. Practical implications – The results of the study show that Bangladeshi consumers prefer to see “Made in Bangladesh” tags when buying consumer products – a significant potential threat that the multinational companies need to address while planning to expand business in Bangladesh. Originality/value – This type of rigorous study on Bangladesh has never been done before. Moreover, the study identifies the difference in ethnocentric behavior of the consumers living in border and non-border areas – a study of ethnocentrism from a different point of view.

scholarly journals A Rare Case of Zosteriform Cutaneous Metastases from a Nasopharyngeal Carcinoma

2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Andrés González García ◽  
Emiliano Grillo Fernández ◽  
Ignacio Barbolla Díaz ◽  
Asunción Ballester ◽  
Héctor Pian ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Herpes Zoster ◽  
Nasopharyngeal Carcinoma ◽  
Metastatic Disease ◽  
Alopecia Areata ◽  
Rare Case ◽  
Point Of View ◽  
Cutaneous Metastases ◽  
Clinical Point ◽  
Scalp Lesions

From a clinical point of view, the most common presentations of cutaneous metastatic disease are papules and nodules. However, a wide morphological spectrum of lesions has been described, including erythematous patches or plaques, inflammatory erysipelas-like lesions, diffuse sclerodermiform lesions with induration of the skin, telangiectatic papulovesicles, purpuric plaques mimicking vasculitis, and alopecia areata like scalp lesions. The so-called zosteriform pattern has been described to be in few cases and to the best of our knowledge has never been described associated with a metastasis of a nasopharyngeal carcinoma. This case highlights the relevance of including cutaneous metastases in the differential diagnosis of patients with nonhealing herpes zoster-like lesions, especially in those with underlying neoplasm recently diagnosed.

scholarly journals Etiopathogenic bases for patellofemoral arthritis development

2018 ◽  
Vol 99 (2) ◽  
pp. 270-278
Author(s):  
F MM Said ◽  
I F Akhtyamov ◽  
A I Kudryavtsev ◽  
A N Nuriakhmetov
Keyword(s):  
Femoral Anteversion ◽  
Point Of View ◽  
Tibial Rotation ◽  
Patellofemoral Arthritis ◽  
Femoral Trochlea ◽  
Anatomical Features ◽  
Q Angle ◽  
High Prevalence ◽  
Clinical Point ◽  
Internal Tibial Rotation

Patellofemoral arthritis is nowadays an actual issue of traumatology and orthopedics. High prevalence of this pathology around the world (6.9 to 36.1%) is associated with multiple etiological causes, responsible for certain difficulties in diagnosis and complexity of determining an individualized pathogenetic method of treatment. The pathology, often occurring in the young age, is called «delayed or late arthritis», due to the fact that it is often ignored in the early stages of its development. This leads, in the final stages of disease, to manifestation of classic osteoarthritis involving all the structures of the knee joint in the process. The literature review is devoted to the study of etiology, pathogenesis and anatomical features of the development of patellofemoral arthritis. From the clinical point of view, the most important factors, influencing patellofemoral arthritis course, are analyzed. They include mechanisms of the disease, anatomical features of patella, trochlear surface and femoral condyles, which affect the disease course. The article discusses the risk factors of patellofemoral arthritis, such as weakness of vastus muscles of quadriceps femoris, increased knee Q-angle, increased femoral anteversion and tibial rotation, abnormalities of patellar and tibial epicondyles morphology. In addition the study presents some data about dysplasia of the condyles and femoral trochlea and patella, disposition of the patella and dysplasia of the quadriceps. Variations of configuration and position of patella affecting its stability are described and presented. The article also focuses on the influence of internal tibial rotation and femoral anteversion on the development of disease, as well as patellar instability as a multifactorial cause.

The High Energy Groups in the Magnetic Spectrum of the Radium C β-Rays

1924 ◽  
Vol 22 (3) ◽  
pp. 369-378 ◽  
Author(s):  
C. D. Ellis
Keyword(s):  
High Frequency ◽  
High Energy ◽  
Point Of View ◽  
Detailed Knowledge ◽  
Very High Frequency ◽  
Magnetic Spectrum ◽  
Γ Rays ◽  
Very High ◽  
Made In

Many years ago Rutherford remarked that the high energy lines of the radium C β-ray spectrum showed the existence of γ-rays of very high frequency, and later he pointed out that their frequencies must be closely connected with the β-ray energies through the quantum relation. Although the truth of Rutherford's point of view has become more and more obvious, no advance in the detailed knowledge of these lines has been made in the last seven years. This spectrum is very complicated and the lines faint.

Epigenome editing by CRISPR/Cas9 in clinical settings: possibilities and challenges

2019 ◽  
Vol 19 (3) ◽  
pp. 215-228 ◽  
Author(s):  
Wen-Di Pei ◽  
Yan Zhang ◽  
Tai-Lang Yin ◽  
Yang Yu
Keyword(s):  
Basic Research ◽  
Point Of View ◽  
Clinical Settings ◽  
Epigenome Editing ◽  
Clinical Point ◽  
Disease Related Genes ◽  
Future Work ◽  
Novel Therapeutic ◽  
Target Effects ◽  
Made In

Abstract Epigenome editing is a promising approach for both basic research and clinical application. With the convergence of techniques from different fields, regulating gene expression artificially becomes possible. From a clinical point of view, targeted epigenome editing by CRISPR/Cas9 of disease-related genes offers novel therapeutic avenues for many diseases. In this review, we summarize the EpiEffectors used in epigenome editing by CRISPR/Cas9, current applications of epigenome editing and progress made in this field. Moreover, application challenges such as off-target effects, inefficient delivery, stability and immunogenicity are discussed. In conclusion, epigenome editing by CRISPR/Cas9 has broad prospects in the clinic, and future work will promote the application of this technology.

BIO-ENERGY FROM PHOTOSYNTHETIC ALLOYS FOR USE IN BIOGUALS AND BIOPRODUCTS

2019 ◽  
pp. 613-618
Author(s):  
Petar Kazakov ◽  
Atanas Iliev ◽  
Emil Ivanov ◽  
Dobri Rusev
Keyword(s):  
Technical Progress ◽  
Point Of View ◽  
Energy Sustainability ◽  
International Activities ◽  
Made In

Significant technical progress has been made in recent years in the development of algae-based bioenergy, and much of industrial and academic R&D projects have diverged from the biofuels strategy. This report summarizes the conclusions of a recently concluded symposium analyzing the prospects for using micro- and macroalgae as a feedstock for biofuels and bioenergy. It discusses international activities for the development of bio-energy and non-energy algae bioproducts, advances in the use of macroalgae (both non-cultivated and cultivated algae). Applications for various biochemical and thermochemical uses, bio-refining capabilities for various products, as well as an in-depth review of the process from the point of view of economy and energy sustainability are also given.

Physical capital stock, technological upgrading and modernisation in Hungary

2005 ◽  
Vol 55 (2) ◽  
pp. 201-221 ◽  
Author(s):  
Andrea Szalavetz
Keyword(s):  
Capital Accumulation ◽  
Physical Capital ◽  
Developed Countries ◽  
Point Of View ◽  
Technology Generation ◽  
Development Policies ◽  
Specific Factors ◽  
Physical Capital Accumulation

This paper discusses the relation between the quality and quantity indicators of physical capital and modernisation. While international academic literature emphasises the role of intangible factors enabling technology generation and absorption rather than that of physical capital accumulation, this paper argues that the quantity and quality of physical capital are important modernisation factors, particularly in the case of small, undercapitalised countries that recently integrated into the world economy. The paper shows that in Hungary, as opposed to developed countries, the technological upgrading of capital assets was not necessarily accompanied by the upgrading of human capital i.e. the thesis of capital skill complementarity did not apply to the first decade of transformation and capital accumulation in Hungary. Finally, the paper shows that there are large differences between the average technological levels of individual industries. The dualism of the Hungarian economy, which is also manifest in terms of differences in the size of individual industries' technological gaps, is a disadvantage from the point of view of competitiveness. The increasing differences in the size of the technological gaps can be explained not only with industry-specific factors, but also with the weakness of technology and regional development policies, as well as with institutional deficiencies.

Endoscopic Surgery of the Broncho-esophageal Diseases. Endoscopic Mucosal Resection in Early Esophageal Cancer.

1996 ◽  
Vol 47 (2) ◽  
pp. 150-154 ◽  
Author(s):  
Hiroyasu Makuuchi ◽  
Hideo Shimada ◽  
Kyoichi Mizutani ◽  
Osamu Chino ◽  
Takao Machimura ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Endoscopic Mucosal Resection ◽  
Endoscopic Surgery ◽  
Early Esophageal Cancer ◽  
Esophageal Diseases ◽  
Mucosal Resection

Der Sommer und Herbst 2003 aus phänologischer Sicht | Summer and autumn 2003 from a phenological point of view

2004 ◽  
Vol 155 (5) ◽  
pp. 142-145 ◽  
Author(s):  
Claudio Defila
Keyword(s):  
Time Series ◽  
New Record ◽  
Point Of View ◽  
Late Spring ◽  
Mean Deviation ◽  
Leaf Shedding ◽  
The Mean ◽  
Very High ◽  
Selection Of

The record-breaking heatwave of 2003 also had an impact on the vegetation in Switzerland. To examine its influences seven phenological late spring and summer phases were evaluated together with six phases in the autumn from a selection of stations. 30% of the 122 chosen phenological time series in late spring and summer phases set a new record (earliest arrival). The proportion of very early arrivals is very high and the mean deviation from the norm is between 10 and 20 days. The situation was less extreme in autumn, where 20% of the 103 time series chosen set a new record. The majority of the phenological arrivals were found in the class «normal» but the class«very early» is still well represented. The mean precocity lies between five and twenty days. As far as the leaf shedding of the beech is concerned, there was even a slight delay of around six days. The evaluation serves to show that the heatwave of 2003 strongly influenced the phenological events of summer and spring.

scholarly journals Competing risks joint models using R-INLA

2021 ◽  
Vol 21 (1-2) ◽  
pp. 56-71
Author(s):  
Janet van Niekerk ◽  
Haakon Bakka ◽  
Håvard Rue
Keyword(s):  
Competing Risks ◽  
Count Data ◽  
Joint Model ◽  
Point Of View ◽  
Spatial Structures ◽  
Joint Models ◽  
Hazard Functions ◽  
Longitudinal Count Data ◽  
Non Gaussian ◽  
Made In

The methodological advancements made in the field of joint models are numerous. None the less, the case of competing risks joint models has largely been neglected, especially from a practitioner's point of view. In the relevant works on competing risks joint models, the assumptions of a Gaussian linear longitudinal series and proportional cause-specific hazard functions, amongst others, have remained unchallenged. In this article, we provide a framework based on R-INLA to apply competing risks joint models in a unifying way such that non-Gaussian longitudinal data, spatial structures, times-dependent splines and various latent association structures, to mention a few, are all embraced in our approach. Our motivation stems from the SANAD trial which exhibits non-linear longitudinal trajectories and competing risks for failure of treatment. We also present a discrete competing risks joint model for longitudinal count data as well as a spatial competing risks joint model as specific examples.

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