scholarly journals The Role of Cellular Biology in Maxilo-facial Surgery and Protective Restorations

2020 ◽  
Vol 70 (12) ◽  
pp. 4377-4380

The essential characteristics of contemporary dental medicine are the precision, avant-garde, technologization and successful clinical purpose of cell therapy with the prospect of further application in the clinical practice of cell therapy methods and other performance methods based on the knowledge of cell biology and regenerative medicine in full function ; despite the very different environments, such teeth can develop normal in adult jaw; thus, if suitable cells can be found that, by combination, produce immature teeth, there is the potential for bio- teeth to become a clinical reality .The maxillary frontal area represents the most important area of the maxillae from an aesthetic point of view and the prosthetic restoration of this area is of primary interest in ensuring the appearance, phonation, incision, in human communication and in the structuring of the individual personality. Affecting the maxillary frontal area or through coronary destruction consecutive cavities and their complications, discolouration, dental malpositions disgraceful or due to lack of dental periodontal units creates problem in the aesthetic prosthetics. These changes existing at the front arcade level cause major disturbances to the physiognomy, to the phonation. In the Clinic of Oral and Maxillofacial Surgery, in a period of 2 years, between 2016 and 2018, we noticed, solved and followed a number of 129 cases; 57 patients-lot endodontic and surgical therapy study; 72 patients, study group prosthetic restorations. Due to the functional role that the maxillary front teeth play, the corrections have to be made within the limits of functional tolerance that fall within the normal occlusal parameters because the functional disturbances dictated only by the aesthetics are not tolerated and can lead to large imbalances. The complex oral rehabilitation of the different clinical cases encountered in the dental practice is largely a challenge for the dentist due to the high degree of different affect but present on all the elements of the system. Keywords: cell therapy method , regenerative medicine, prosthetic restoration

2017 ◽  
Vol 68 (10) ◽  
pp. 2373-2377
Author(s):  
Mihaela Monica Scutariu ◽  
Vlad Danila ◽  
Corina Ciupilan ◽  
Oana Elena Ciurcanu

Anesthesia and the degree of control over the perception of pain depends on the personality of the individual, the socio-economic conditions, potential previous painful experiences and, last but not least, on fatigue and fear of the dentist. The perception of pain in patients is closely connected to their mental state. Pain is defined as a sensation of discomfort, with wide variations, both in quality and intensity, for different people in seemingly identical conditions; an unpleasant sensitive and emotional phenomena connected to the threat of a wound or caused in the tissues or described in the terms of this disease. The essential element of any type of anesthesia is analgesia, an effect which in some cases cannot be achived, due to the patient�s particularities or the physician�s lack of experience in anesthesia. Locoregional anesthesia (LRA) represents the blocking of the nociceptive sensitive and sympathetic autonomic afferents as well as that of motor efferents at the level of peripheral nerves� axons, by means of local anesthetic. To achieve the set purpose, we carried out a study on a representative human sample comprised of 10.123 patients treated in the Oral and Maxillofacial Surgery Clinic (Ambulatory) from the County Clinic Emergency Hospital St. Spiridon Iasi, between 01.01.2015-31.12.2016. The reason for the exclusion of certain categories of patients in the reseach was: the patients with a special conditions background require individual pre-anesthesia schemes, personalised for the nature of the pre-existing general condition, which must be further approved by the attending specialist physician : cardiologist, internist, diabetologist; children under 18 years old, with a high degree of anxiety; a high precentage of elderly patients, over 60 years old, possess a combination of general issues, thus requiring a special approach. The thoroughness lying at the core of the anesthetic practice, most especially the safegurading of a technical accuracy in the performance of anesthesia [12,], instead of improvisations, the lack of anatomical and stomatological training in general and the resulting inefficiency as such, is the underlying in-depth structuring element of this paper.


2013 ◽  
Vol 59 (1) ◽  
pp. 40-43 ◽  
Author(s):  
Alina Iacob ◽  
Bálint Bögözi

Abstract Background: In the medical literature there are multiple reconstructive procedures for small and medium size defects of the lower lip, but only a few methods for larger defects involving the whole lower lip. Choosing the repairing procedure for larger lower lip defects must take into account two aspects: flap or flaps used should be local flaps, and suture lines should correspond to the natural facial creases or follow the functional lines of different facial aesthetic units. Finally, the flap or flaps should be large enough to restore the entire postexcisional defect. However, the more tissue is lost from the lower lip, the more challenging the reconstruction is from a functional and cosmetic point of view. Material and methods: During the last 2 years in the Oral and Maxillofacial Surgery Department of the County Emergency Clinical Hospital in Tîrgu Mureș, the unilateral Fujimori technique has been successfully used for the reconstruction of large lower lip defects in 4 patients with extended, neglected squamous cell carcinomas involving almost the whole lower lip tissue. These patients underwent complex surgical and oncological treatment. Surgery was performed in two stages: first, excision of the tumor and immediate lip reconstruction, and then removal of submandibular lymph nodes (level I), in the second stage. Results: The aesthetic and functional recovery of these patients was very good, with no need of other subsequent surgical corrections. Conclusions: The postoperative reconstruction of large defects of the lower lip is far from optimal, but it is very important to restore an adequate muscle function, the lip continence and a satisfactory facial appearance.


2019 ◽  
Vol 98 (12) ◽  
pp. 1294-1304 ◽  
Author(s):  
M.B. Blatz ◽  
G. Chiche ◽  
O. Bahat ◽  
R. Roblee ◽  
C. Coachman ◽  
...  

One of the main goals of dental treatment is to mimic teeth and design smiles in a most natural and aesthetic manner, based on the individual and specific needs of the patient. Possibilities to reach that goal have significantly improved over the last decade through new and specific treatment modalities, steadily enhanced and more aesthetic dental materials, and novel techniques and technologies. This article gives an overview of the evolution of aesthetic dentistry over the past 100 y from a historical point of view and highlights advances in the development of dental research and clinical interventions that have contributed the science and art of aesthetic dentistry. Among the most noteworthy advancements over the past decade are the establishment of universal aesthetic rules and guidelines based on the assessment of natural aesthetic parameters, anatomy, and physiognomy; the development of tooth whitening and advanced restorative as well as prosthetic materials and techniques, supported by the pioneering discovery of dental adhesion; the significant progress in orthodontics and periodontal as well as oral and maxillofacial surgery; and, most recently, the implementation of digital technologies in the 3-dimensional planning and realization of truly natural, individual, and aesthetic smiles. In the future, artificial intelligence and machine learning will likely lead to automation of aesthetic evaluation, smile design, and treatment-planning processes.


Author(s):  
María José Miranda Suárez ◽  

Innovations in regenerative medicine and cell therapy have made possible multiple breakings in the laws and paradigms that determined the beginnings of 20th century biology. The destabilisation of categories and heteronormative dichotomies that demarcated this science made possible the irruption of studies that separated genetic research from sex. Even so, the current implementation of these techno-scientific developments produce other types of exclusion mechanisms we will analyse from a bio-economic point of view: from the reinforcement of the conditions of vulnerability of women donors, to the support of therapeutic promises that semiotically disconnect the contexts of uncertainty of these technologies or the implementation of a performative understanding of health in terms of individual consumption.


Author(s):  
Nagendra Kumar Chandrawanshi ◽  
Shekhar Verma

Cancer is the most prevalent and dangerous disease, and it leads to millions of deaths worldwide. Generally, metastatic cancer cells are not eradication by conventional surgical operative or chemotherapy-based treatment. New pathways have been established in various arenas such as unique biology, modulators regulatory mechanism, directional migration, self-renewal, etc. The individual pathways can be employed as therapeutic carriers, specific drug targeting, generation of acquiring nature immune cells, and regenerative medicine. The present scenario, stem cell therapy, focused on a promising tool for targeted cancer treatment. Stem cells also utilized as viruses and nanoparticles carry to enhance the primary therapeutic application in various dimensions such as cancer target therapy, regenerative medicine, immune-modulating therapy, and anticancer drugs screening. Furthermore, the rapid development in next-generation sequencing techniques and cancer genomics and proteomics analysis approaches are making therapeutics targeting organ-specific cancer more precise and efficient.


2013 ◽  
Vol 10 (1) ◽  
pp. 15-19 ◽  
Author(s):  
Kazuto Hoshi ◽  
Yuko Fujihara ◽  
Yukiyo Asawa ◽  
Satoru Nishizawa ◽  
Sanshiro Kanazawa ◽  
...  

2015 ◽  
Vol 43 (7) ◽  
pp. 1078-1081 ◽  
Author(s):  
Pablo Castelo-Baz ◽  
Yago Leira-Feijoo ◽  
Juan Manuel Seoane-Romero ◽  
Pablo Varela-Centelles ◽  
Juan Seoane

10.26458/1414 ◽  
2014 ◽  
Vol 14 (1) ◽  
pp. 33
Author(s):  
Gabriela IOSIF

From the point of view of Durkheim, institutions are ways of acting, feeling and thinking, expressing any social act. Institutions have stringent action on the individual, have its own existence, independent of individual manifestations, which are distinctive for a given group, being accepted by all members. Types of social institutions are economic institutions, educational, political, cultural and family. Within institutions, communication is an inherent phenomenon.For Katz and Kahn "communication is a social process of great relevance to the functioning of each group, organization or society," the very essence of the social system or organization. The organizational structure provides stability for human communication and facilitates administrative tasks. (Rogers Everett M. and Agarwala-Rogers Rekha, 1976, p. 6). Therefore, an effective institutional communication adds value to any institution. 


Sign in / Sign up

Export Citation Format

Share Document