Effects of Chinese herbal medicine Danzhi Jiangtang Capsule and exercise on JNK signaling pathway in pancreatic tissues of diabetic rats

2012 ◽  
pp. 1279-1285
Author(s):  
YJ Wu
Keyword(s):  
Herbal Medicine ◽  
Signaling Pathway ◽  
Chinese Herbal Medicine ◽  
Diabetic Rats ◽  
Jnk Signaling ◽  
Chinese Herbal ◽  
Jnk Signaling Pathway

scholarly journals Ameliorative Anti-Diabetic Activity ofDangnyosoko, a Chinese Herbal Medicine, in Diabetic Rats

2007 ◽  
Vol 71 (6) ◽  
pp. 1527-1534 ◽  
Author(s):  
Jong-Dae KIM ◽  
Seock-Man KANG ◽  
Mee-Yeon PARK ◽  
Tae-Young JUNG ◽  
Hae-Yun CHOI ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Diabetic Rats ◽  
Chinese Herbal

scholarly journals Preventive Effects of the Chinese Herbal Medicine Prescription Tangkuei Decoction for Frigid Extremities on Sciatic Neuropathy in Streptozotocin-Induced Diabetic Rats

2016 ◽  
Vol 2016 ◽  
pp. 1-11
Author(s):  
Pengsong Liu ◽  
Yuanyuan Bian ◽  
Hong Zhang ◽  
Aiming Jia
Keyword(s):  
Herbal Medicine ◽  
Sciatic Nerve ◽  
Chinese Herbal Medicine ◽  
Nerve Conduction ◽  
Diabetic Rats ◽  
Chinese Herbal ◽  
Conduction Velocities ◽  
Medicine Prescription ◽  
Sciatic Nerves ◽  
Vegf Protein

Ischemia and hypoxia are important physiological changes in diabetic peripheral neuropathy (DPN). Chinese herbal medicine prescription Tangkuei Decoction for Frigid Extremities (TDFE) is useful for increasing blood flow. To help determine whether TDFE could protect the peripheral nerves of diabetic patients from the degeneration caused by high blood glucose, TDFE was administered to streptozotocin-induced diabetic rats for 6 or 12 weeks. Plantar thermal stimulation reaction time thresholds, sciatic nerve conduction velocities, and the levels of HIF-1αmRNA, HIF-1αprotein, VEGF protein, and the endothelial marker vWF in sciatic nerves were measured at the end of the sixth and twelfth weeks. The thermal thresholds and sciatic nerve conduction velocities of the rats differed after 12 weeks, and the sciatic nerves of the diabetic rats that were given TDFE displayed higher levels of HIF-1αprotein, VEGF protein, and HIF-1αmRNA than those of the diabetic model rats. The results at 6 weeks differed from those at 12 weeks. These results suggest that the early preventive application of TDFE effectively delayed the development of DPN and that TDFE increased HIF-1αmRNA levels in the sciatic nerves of diabetic rats through 12 weeks of treatment.

Effect of Gosha-jinki-gan (Chinese herbal medicine: Niu-Che-Sen-Qi-Wan) on insulin resistance in streptozotocin-induced diabetic rats

2003 ◽  
Vol 59 (2) ◽  
pp. 103-111 ◽  
Author(s):  
Xiaochen Hu ◽  
Juichi Sato ◽  
Yoshiharu Oshida ◽  
Ming Xu ◽  
Gustavo Bajotto ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Diabetic Rats ◽  
Chinese Herbal
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