Antioxidant and Anticancer Activities of Methanol Extracts Prepared from Different Parts of Jangseong Daebong Persimmon (Diospyros kaki cv. Hachiya)

2010 ◽  
Vol 39 (4) ◽  
pp. 500-505 ◽  
Author(s):  
Young-Hong Jo ◽  
Ji-Won Park ◽  
Jeung-Min Lee ◽  
Gwang-Hwan Ahn ◽  
Hae-Ryong Park ◽  
...  
2019 ◽  
Vol 19 (13) ◽  
pp. 1577-1587
Author(s):  
Sumana Saha ◽  
Tapan Kumar Giri

Background: In the last decade, many new avenues of cancer treatment have opened up but the costs of treatment have sky-rocketed too. Hence, screening of indigenously available plant and animal resources for anti-carcinogenic potential is an important branch of anticancer research. The effort has been made through this comprehensive review to highlight the recent developments of anticancer therapies using different parts of papaya plant extract. Methods: In search of the naturally existing animals and plants for anticarcinogenic potential, papaya plant has been exploited by the scientist working in this research field. A widespread literature search was performed for writing this review. Results: Different constituents of Carica papaya responsible for anticancer activities have been discussed. Papaya extract for the treatment of breast, liver, blood, pancreas, skin, prostate, and colon cancer have also been reported. Finally, the various formulation approach using Carica papaya extract have been highlighted. Conclusion: The information provided in this review might be useful for researchers in designing of novel formulation of Carica papaya extract for the treatment of cancer.


2019 ◽  
Vol 9 (2) ◽  
pp. 98-124 ◽  
Author(s):  
Mohammad Yasir ◽  
Manish K. Tripathi ◽  
Pushpendra Singh ◽  
Rahul Shrivastava

Background:Medicinal plants are rich source of large variety of lead compounds. The plants of genus Glycosmis or its different parts valued for its therapeutic and medicinal qualities. Glycosmis belongs to the family Rutaceae.Objective:The genus Glycosmis is a rich source of pharmacologically and biologically active secondary metabolites, such as alkaloids, flavonoids, phenolic glycosides, quinones, terpenoids, glycerides isolated from different parts of Glycosmis plant. The objectives of this review is to provide updatedand complete information on the distribution, phytochemical, pharmacological, and toxicity research of Glycosmis species.Results:About 233 phytoconstituents are isolated from this genus. Recent interest in this genus has focused on isolating and identifying of different phytoconstituents that exhibit potent antioxidant, antibacterial, antiviral and anticancer activities. They show good cytotoxic activity against various cancer cell lines and also reported for good antiviral and immunomodulatory activity. In this support convincing evidence in experimental animal models are available.Conclusion:This review summarizes information about the isolated compounds their bioactivities related to same compounds present in other plants including pharmacological activities of plant extract of Glycosmis genus.


2013 ◽  
Vol 2013 ◽  
pp. 1-13 ◽  
Author(s):  
El-Sayed S. Abdel-Hameed ◽  
Salih A. Bazaid ◽  
Mahmood S. Salman

Ward Taifi (Taif rose) is considered one of the most important economic products of Taif, Saudi Arabia. In this study both fresh and dry Taif rose were biologically and phytochemically investigated. The 80% methanol extracts andn-butanol fractions of dry and fresh Taif rose had high radical scavenging activity toward artificial 1,1-diphenyl picrylhydrazyl (DPPH)•radical with SC50values range 5.86−12.24 µg/ml whereas the aqueous fractions showed weak activity. All samples hadin vitroanticancer activity toward HepG2 with IC50< 20 µg/ml which fall within the criteria of the American Cancer Institute. High positive correlation appeared between the antioxidant activity and total phenolics whereas there is no correlation between total phenolics and anticancer activity. The LC-ESI(− ve)-MS analysis of all extracts indicate the presence of phenolic compounds belonging to hydrolysable tannins and flavonol glycosides. In conclusion, the presence of this is considered to be the first phytochemical report that identifies the major compounds in dry and fresh roses using HPLC-ESI-MS. The methanol extracts and itsn-butanol and aqueous fractions for both fresh and dry Taif rose could be used as preventive and therapeutic effective natural agents for diseases in which free radicals involved after morein vitroandin vivostudies.


2018 ◽  
Vol 4 (6) ◽  
pp. 870-877
Author(s):  
Yessian Sharmila Juliet ◽  
Kandasamy Kalimuthu ◽  
Vajjiram Chinnadurai ◽  
Venkatachalam Ranjitha ◽  
Ammasai Vanitha

Author(s):  
Jovica Tomović ◽  
Marijana Kosanić ◽  
Branislav Ranković ◽  
Perica Vasiljević ◽  
Stevo Najman ◽  
...  

Abstract The aim of this study is to investigate the chemical composition of methanol extracts of the lichens Pleurosticta acetabulum and Cladonia subulata and their antioxidant, and anticancer activities. The phytochemical analysis of the extracts of lichens was determined by HPLC-UV method. The predominant phenolic compounds in these extracts were norstictic acid and salazinic acids in P. acetabulum, while hypoprotocetraric acid and fumarprotocetraric acid were the major metabolites detected in C. subulata. Total phenolics and flavonoids in the extracts were determined spectrophotometrically, with the varied amount from 21.31 to 73.45 mg GA/g and from 8.48 to 15.42 mg RU/g, respectively. The lichen extracts showed comparable and strong antioxidant activity, exhibited higher DPPH and hydroxyl radical scavengings, inhibitory activity towards lipid peroxidation and reducing power. Cytotoxic effects of lichens were tested against HeLa S3 and LS174 cell lines using MTT method.The cytotoxic effects of P. acetabulum and C. subulata extracts toward two cancer cell lines were in the range from 39.17 to >200 μg/mL IC50 value. The present study showed that the tested extracts of lichens demonstrated important antioxidant and anticancer effects. That suggests that these lichens can be used as new sources of the natural antioxidants and anti-cancer compounds.


2014 ◽  
Vol 46 (4) ◽  
pp. 505-510 ◽  
Author(s):  
In Hwa Jeon ◽  
Hyun Ju Kang ◽  
Hyun-Seo Lee ◽  
Jun Ho Shin ◽  
Yong Gyoun Park ◽  
...  

2013 ◽  
Vol 1 (3) ◽  
pp. 137-144 ◽  
Author(s):  
Sushika Joshi ◽  
Anish Kumar Karna

Phytochemical screening of extracts of Ocimum Sanctum revealed the presence of fatty acids, steroids, triterpenoid, phenolic compound, flavonoid, glycoside, quinines, and carotenoids. β-sitosterol and Ursolic acid were isolated from leaves of the plant by using column chromatography and  identification  of these compounds were performed with the help of melting points, Co-TLC  and spectroscopic techniques such as IR, 1HNMR and 13 CMR. GC-MS of hexane fraction showed presence of pentanal, sotolone, hexane-3-one, hexane-2-ol, caryphyllene, benzene 1,2 di-carbolylic acids, isoeugenol, cavracrol and eugenol compounds. The brine shrimp bio assay showed  LC50 value 213.7,  97.72 and 21.87 for hexane, ethyl acetate and methanol extracts of leaves respectively, where as LC50 value 169.84, 141.25 and 151.35 for hexane, ethyl acetate and methanol  extracts of stem respectively. All extracts are pharmacologically active.DOI: http://dx.doi.org/10.3126/ijasbt.v1i3.8609 Int J Appl Sci Biotechnol, Vol. 1(3) 2013 : 137-144


2012 ◽  
Vol 2 (12) ◽  
pp. 960-965 ◽  
Author(s):  
Badakhshan Mahdi-Pour ◽  
Subramanion L Jothy ◽  
Lachimanan Yoga Latha ◽  
Yeng Chen ◽  
Sreenivasan Sasidharan

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