Inhibitory Effects of Myelophycus simplex Papenfuss Methanol Extract on Melanogenesis in B16F10 Melanoma Cells

2017 ◽  
Vol 46 (1) ◽  
pp. 34-38
Author(s):  
Hyang Suk Kim ◽  
Ji Min Cheon ◽  
Da Hye Kwon ◽  
Eun Ok Choi ◽  
Min Ju Kim ◽  
...  
Keyword(s):  
Methanol Extract ◽  
Melanoma Cells ◽  
Inhibitory Effects ◽  
B16f10 Melanoma ◽  
B16f10 Melanoma Cells

scholarly journals Kinetics of Mushroom Tyrosinase and Melanogenesis Inhibition byN-Acetyl-pentapeptides

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Ching-Yi Lien ◽  
Ching-Yu Chen ◽  
Shih-Ting Lai ◽  
Chin-Feng Chan
Keyword(s):  
Kojic Acid ◽  
Lag Time ◽  
Melanoma Cells ◽  
Dependent Manner ◽  
Mushroom Tyrosinase ◽  
Inhibitory Effects ◽  
B16f10 Melanoma ◽  
B16f10 Melanoma Cells ◽  
Kinetics Of ◽  
Dose Dependent

We investigated the kinetics of 4N-acetyl-pentapeptides, Ac-P1, Ac-P2, Ac-P3, and Ac-P4, regarding inhibition of mushroom tyrosinase activity. The peptides sequences of Ac-P1, Ac-P2, Ac-P3, and Ac-P4 were Ac-RSRFK, Ac-KSRFR, Ac-KSSFR, and Ac-RSRFS, respectively. The 4N-acetyl-pentapeptides were able to reduce the oxidation ofL-DOPA by tyrosinase in a dose-dependent manner. Of the 4N-acetyl-pentapeptides, only Ac-P4 exhibited lag time (80 s) at a concentration of 0.5 mg/mL. The tyrosinase inhibitory effects of Ac-P4 (IC500.29 mg/mL) were more effective than those of Ac-P1, Ac-P2, and Ac-P3, in which IC50s were 0.75 mg/mL, 0.78 mg/mL, and 0.81 mg/mL, respectively. Kinetic analysis demonstrated that all 4N-acetyl-pentapeptides were mixed-type tyrosinase inhibitors. Furthermore, 0.1 mg/mL of Ac-P4 exhibited significant melanogenesis inhibition on B16F10 melanoma cells and was more effective than kojic acid. The melanogenesis inhibition of Ac-P4 was dose-dependent and did not induce any cytotoxicity on B16F10 melanoma cells.

Inhibitory Effects of Pigmentation in B16F10 Melanoma Cells from Schizandra chinensis Fractions

2020 ◽  
Vol 21 (1) ◽  
pp. 171-182
Author(s):  
Han-Hyuk Kim ◽  
Hyung-Jin Na ◽  
A-Leum Jeong ◽  
Mi-Ja Seo
Keyword(s):  
Melanoma Cells ◽  
Inhibitory Effects ◽  
B16f10 Melanoma ◽  
B16f10 Melanoma Cells ◽  
Schizandra Chinensis

scholarly journals Inhibitory Effects of Saururi chinensis Extracts on Melanin Biosynthesis in B16F10 Melanoma Cells

2013 ◽  
Vol 36 (5) ◽  
pp. 772-779 ◽  
Author(s):  
Do Hyun Lee ◽  
Dong Ha Kim ◽  
In Young Oh ◽  
So Young Kim ◽  
Yun Young Lim ◽  
...  
Keyword(s):  
Melanoma Cells ◽  
Inhibitory Effects ◽  
B16f10 Melanoma ◽  
Melanin Biosynthesis ◽  
B16f10 Melanoma Cells

Inhibitory Effects of Dryopteris erythrosora Extract on Tyrosinase Activity and Melanin Production in B16F10 Melanoma Cells

KSBB Journal ◽  
2020 ◽  
Vol 35 (3) ◽  
pp. 228-234
Author(s):  
Yeon-Su Koo ◽  
Taejin Park ◽  
Ji Han Sim ◽  
Min-Seon Kim ◽  
Seung-Young Kim
Keyword(s):  
Melanoma Cells ◽  
Tyrosinase Activity ◽  
Inhibitory Effects ◽  
B16f10 Melanoma ◽  
Melanin Production ◽  
B16f10 Melanoma Cells

scholarly journals Betulinic acid augments the inhibitory effects of vincristine on growth and lung metastasis of B16F10 melanoma cells in mice

2004 ◽  
Vol 90 (8) ◽  
pp. 1672-1678 ◽  
Author(s):  
N Sawada ◽  
K Kataoka ◽  
K Kondo ◽  
H Arimochi ◽  
H Fujino ◽  
...  
Keyword(s):  
Lung Metastasis ◽  
Betulinic Acid ◽  
Melanoma Cells ◽  
Inhibitory Effects ◽  
B16f10 Melanoma ◽  
B16f10 Melanoma Cells
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