scholarly journals The Protective Effect of Annona Extracts on Renal Histopathology Induced by Ethylene Glycol in Male Rabbits

2020 ◽  
Keyword(s):  
Ethylene Glycol ◽  
Protective Effect ◽  
Renal Histopathology

Protective effect of the hydro-alcoholic extract of Rubia cordifolia roots against ethylene glycol induced urolithiasis in rats

2010 ◽  
Vol 48 (4) ◽  
pp. 1013-1018 ◽  
Author(s):  
Kalyani Divakar ◽  
A.T. Pawar ◽  
S.B. Chandrasekhar ◽  
S.B. Dighe ◽  
Goli Divakar
Keyword(s):  
Ethylene Glycol ◽  
Protective Effect ◽  
Alcoholic Extract ◽  
Rubia Cordifolia

Chemoprotection of ethylene glycol monoethyl ether-induced reproductive toxicity in male rats by kolaviron, isolated biflavonoid from Garcinia kola seed

2011 ◽  
Vol 31 (5) ◽  
pp. 506-517 ◽  
Author(s):  
IA Adedara ◽  
EO Farombi
Keyword(s):  
Vitamin E ◽  
Ethylene Glycol ◽  
Protective Effect ◽  
Reproductive Toxicity ◽  
Male Rats ◽  
Antioxidant Systems ◽  
Sod Activity ◽  
Garcinia Kola ◽  
Monoethyl Ether ◽  
Glycol Monoethyl Ether

The present study investigated the protective effect of kolaviron, a biflavonoid from the seed of Garcinia kola, on ethylene glycol monoethyl ether (EGEE)–induced reproductive toxicity in male rats. The protective effect of kolaviron was validated using vitamin E, a standard antioxidant. EGEE was administered at a dose of 200 mg/kg. Other groups of rats were simultaneously treated with kolaviron (100 and 200 mg/kg) and vitamin E (50 mg/kg) for 14 days. EGEE treatment resulted in significant decrease in glutathione (GSH) level, superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) activities but markedly increased the glutathione-S-transferase (GST) and lactate dehydrogenase (LDH) activities in the testes. In the spermatozoa, administration of EGEE caused significant decrease in the activities of CAT, GPx, GST and LDH as well as in the level of GSH but significantly increased SOD activity with concomitant increase in hydrogen peroxide and malondialdehyde levels in both testes and spermatozoa. EGEE-exposed rats showed marked testicular degeneration with concomitant decrease in spermatozoa quantity and quality. Overall, EGEE causes reproductive dysfunction in rats by altering antioxidant systems in the testes and spermatozoa. Kolaviron or vitamin E exhibited protective effects against EGEE-induced male reproductive toxicity by enhancement of antioxidant status and improvement in spermatozoa quantity and quality.

scholarly journals Effect of cryoprotectant on the motility, viability, fertilization, and DNA integrity of naleh fish Barbonymus sp. (Cyprinidae) sperm

2021 ◽  
Vol 58 ◽  
pp. e168702
Author(s):  
Siti Maulida ◽  
Kartini Eriani ◽  
Firman Muhammad Nur ◽  
Nur Fadli ◽  
Agung Setia Batubara ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Protective Effect ◽  
Egg Yolk ◽  
Dna Integrity ◽  
Similar Concentration ◽  
Breeding Programs ◽  
Ringer’S Solution ◽  
Cryopreserved Sperm ◽  
Cryopreservation Method ◽  
Egg Fertility

Naleh fish Barbonymus sp. is a commercial freshwater fish, which is indigenous to Aceh, Indonesia. The population of this species has declined over the years as a result of habitat perturbations and overfishing. Hence, the crucial need to develop a cryopreservation method to support breeding programs. This involved the use of a cryoprotectant as an important component. The objective of this study, therefore, was to explore the best cryoprotectant for naleh fish spermatozoa, and a total of five types were tested. These include the DMSO, Methanol, Ethanol, Glycerol, and Ethylene Glycol at a similar concentration of 10%, which were individually combined with 15% egg yolk, and every treatment was performed in three replications. Conversely, Ringer’s solution was adopted as an extender, and the sperm was cryopreserved in liquid nitrogen for 15 days. The results showed significant influence on sperm motility and viability, as well as egg fertility of naleh fish (P <0.05), although the DMSO provided the best outcome, compared to others at 47.17%, 50.13%, and 45.67%, respectively. Furthermore, DNA fragmentation had not occurred in the fresh and cryopreserved sperm samples, indicating the protective effect of tested cryoprotectants. It is concluded that the 10% DMSO and 15% egg yolk is the best cryoprotectant for naleh fish spermatozoa.

scholarly journals Protective Effect of Bee Pollen In Acute Kidney Injury, Proteinuria, And Crystalluria Induced By Ethylene Glycol Ingestion In Rats

2021 ◽  
Author(s):  
Asmae Elghouizi ◽  
Noori Al-Waili ◽  
Nawal Elmenyiy ◽  
Salma Elfetri ◽  
Abderrazak Aboulghazi ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Ethylene Glycol ◽  
Protective Effect ◽  
Urine Volume ◽  
Kidney Tissue ◽  
Kidney Injury ◽  
Histopathological Study ◽  
Pollen Extract ◽  
Bee Pollen ◽  
Antioxidant Content

Abstract Oxidative stress plays a role in hyperoxaluria-induced kidney injury and crystallization. Bee pollen is a hive product with a high content of antioxidants. The antioxidant content and protective effect of bee pollen extract (BPE) against ethylene glycol (EG) induced crystalluria and acute kidney injury (AKI) were investigated. Ten groups of male Wistar rats were treated with EG, cystone (500 mg/kg) or BPE at doses 100, 250, and 500 mg/ kg. On day 30, blood and urine samples were collected for analysis. Kidneys were removed for histopathological study. The antioxidant activity of BPE was assessed, and its total phenols and flavonoids were determined. EG significantly increased urine pH, volume, calcium, phosphorus, uric acid, and protein, and blood urea, creatinine, and liver enzymes (P<0.05). It decreased creatinine clearance and urine magnesium and caused crystalluria. Treatment with BPE or cystone mitigates EG's effect; BPE was more potent than cystone (P<0.05). BPE increases urine volume, sodium, and magnesium compared to the control and EG treated groups. BPE reduces proteinuria and prevents AKI, crystalluria, liver injury, and histopathological changes in the kidney tissue caused by EG. BPE might have a protective effect against EG-induced AKI, crystalluria, and proteinuria, and stone deposition, most likely by its antioxidant content and activity.

Protective Effect of a Potent Antioxidant, Pomegranate Juice, in the Kidney of Rats with Nephrolithiasis Induced by Ethylene Glycol

2008 ◽  
Vol 22 (12) ◽  
pp. 2723-2732 ◽  
Author(s):  
Volkan Tugcu ◽  
Eray Kemahli ◽  
Emin Ozbek ◽  
Yasar Volkan Arinci ◽  
Mehmet Uhri ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Protective Effect ◽  
Pomegranate Juice
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