scholarly journals New Approaches In The Diagnosis Of Oral Hemangiomas

Author(s):  
Karimov M.A. ◽  
Mamarasulova D.Z. ◽  
Sadykov R.R. ◽  
Nurmatova Kh.Kh.

Scientific work was carried out on the basis of the Tashkent Medical Academy, Department of Surgery (1st city hospital), and Andijan Medical Institute, Department of Oncology from 2015-2020.  Clinical material includes 175 patients.  The comparison group consisted of 100 patients who were treated in various hospitals in Tashkent and regions of Uzbekistan.  According to the classification of vascular anomalies, the majority of patients with benign vascular tumors (DBT) were diagnosed with infantile hemangioma (IG) - 82.0%, congenital hemangioma (VH) - 11.4%, pyogenic granuloma (PG) - 5.8%.  Average age of patients: children - 1.2 ± 0.4, adults - 27 ± 1.2 years.  The frequency of DSO in girls was 78%, in boys - 22%.  Localization area: lip - 57.6%, cheek 8%, tongue 26.3%.  Complications of DSO: anatomical disorders, edema, bleeding, pain, infection, respiratory disorders occurred in 83.7% of patients.

2003 ◽  
Vol 6 (6) ◽  
pp. 495-510 ◽  
Author(s):  
Beatriz Berenguer ◽  
John B. Mulliken ◽  
Odile Enjolras ◽  
Lawrence M. Boon ◽  
Michel Wassef ◽  
...  

We define the histopathologic findings and review the clinical and radiologic characteristics of rapidly involuting congenital hemangioma (RICH). The features of RICH are compared to the equally uncommon noninvoluting congenital hemangioma (NICH) and common infantile hemangioma. RICH and NICH had many similarities, such as appearance, location, size, and sex distribution. The obvious differences in behavior served to differentiate RICH, NICH, and common infantile hemangioma. Magnetic resonance imaging (MRI) of the three tumors is quite similar, but some RICH also had areas of inhomogeneity and larger flow voids on MRI and arterial aneurysms on angiography. The histologic appearance of RICH differed from NICH and common infantile hemangioma, but some overlap was noted among the three lesions. RICH was composed of small-to-large lobules of capillaries with moderately plump endothelial cells and pericytes; the lobules were surrounded by abundant fibrous tissue. One-half of the specimens had a central involuting zone(s) characterized by lobular loss, fibrous tissue, and draining channels that were often large and abnormal. Ancillary features commonly found were hemosiderin, thrombosis, cyst formation, focal calcification, and extramedullary hematopoiesis. With one exception, endothelial cells in RICH (as in NICH) did not express glucose transporter-1 protein, as does common infantile hemangioma. One RICH exhibited 50% postnatal involution during the 1st year, stopped regressing, was resected at 18 months, and was histologically indistinguishable from NICH. In addition, several RICH, resected in early infancy, also had some histologic features suggestive of NICH. Furthermore, NICH removed early (2–4 years), showed some histologic findings of RICH or were indistinguishable from RICH. We conclude that RICH, NICH, and common infantile hemangioma have overlapping clinical and pathologic features. These observations support the hypothesis that these vascular tumors may be variations of a single entity ab initio. It is unknown whether the progenitor cell for these uncommon congenital vascular tumors is the same as for common infantile hemangioma.


2018 ◽  
Author(s):  
Javier A Couto ◽  
Arin K Greene

Vascular anomalies are common pediatric lesions affecting approximately 5% of the population. Lesions are broadly classified into tumors and malformations. The most common tumors are infantile hemangioma, congenital hemangioma, pyogenic granuloma, and kaposiform hemangioendothelioma. The major malformations are capillary, lymphatic, venous, and arteriovenous. Almost all lesions can be diagnosed by the history and physical examination. Ultrasonography is usually the first-line imaging study to confirm a diagnosis. Management of vascular anomalies is based on the type of lesion. Treatments include resection, systemic pharmacotherapy, intralesional drugs, laser, sclerotherapy, and/or embolization. Most patients are best managed in an interdisciplinary vascular anomalies center. This review contains 9 figures, 2 tables and 29 references Key words: arteriovenous, capillary, congenital, hemangioma, kaposiform, lymphatic, malformation, pyogenic, vascular, venous


2021 ◽  
Vol 20 (1) ◽  
pp. 145-155
Author(s):  
L. A. Khachatryan ◽  
I. I. Chikvina ◽  
I. S. Kletskaya

Congenital hemangiomas are rare benign vascular tumors that develop in utero and are fully formed by the time of birth. Depending on the ability to involution, there are three subtypes: RICH (repidly involuting congenital hemangioma), NICH (non involuting congenital hemangioma), PICH (partially involuting congenital hemangioma). PICH may be accompanied by thrombocytopenia and consumption coagulopathy. Despite clearly defined clinical and histological characteristics, it can be difficult to make a differential diagnosis between congenital hemangiomas and other vascular tumors (infantile hemangioma, kaposiform hemangioendothelioma/“fascicular” angioma and others). The clinical case in the article of a vascular tumor in a newborn complicated by thrombocytopenia and consumption coagulopathy was regarded as Kazabach-Merritt syndrome, which is based on kaposiform hemangioendothelioma/“fascicular” angioma. Rapid regression of the tumor and recovery of hemogram and coagulogram parameters, as well as anamnesis of the disease and initial characteristics of the tumor forced to reconsider the diagnosis. Based on the histological picture, the diagnosis of congenital hemangioma, RICH, was confirmed. Verification of the diagnosis made it possible to change therapeutic tactics and avoid chemotherapy. A giant hemangioma, accompanied by thrombocytopenia and consumption coagulopathy, may have a very favorable outcome – a complete resolution of the pathological process inherent in its natural course. The patient's parents agreed to use the information, including the child's photo, in scientific research and publications. 


2021 ◽  
Vol 13 (3) ◽  
pp. 347-356
Author(s):  
Aoife Naughton ◽  
Ariel Yuhan Ong ◽  
Goran Darius Hildebrand

Infantile hemangiomas are common benign vascular tumors but are rarely found in an intracranial location. Our literature review identified 41 reported cases. There is no general consensus on management of these rare lesions and until recently, treatment was limited to surgery or pharmacological management with steroids or interferon. Although beta-blockers have been widely prescribed in the treatment of cutaneous infantile hemangiomas since 2008, their use in the treatment of intracranial infantile hemangiomas has been minimal. We present a case of infantile hemangioma affecting the right orbit, associated with intracranial extension, causing intermittent right facial nerve palsy. The patient achieved an excellent outcome following combined treatment with oral propranolol and topical timolol maleate 0.5%, with complete regression of the lesion by 4 months. We conclude that beta-blockers are a safe and effective treatment of intracranial infantile hemangiomas and can be employed as first-line management of these lesions.


2021 ◽  
pp. 58-62
Author(s):  
G. V. Zyrina ◽  
T. A. Slyusa

The purpose of the study. To study clinical and neuroimaging features of chronic cerebral ischemia (CCI) in polycythemia vera (PV).Materials and methods. 66 patients with PV were examined – the main group (43 men, 23 women; mean age 62.0 ± 3.4 years), of which 64 (97.0%) patients were diagnosed with CCI. The comparison group consisted of 85 patients with CCI (34 men, 51 women; mean age 67.7 ± 4.6 years), who developed against the background of cerebral vascular atherosclerosis and arterial hypertension. To identify cognitive disorders, we used Mini Mental State Examination (MMSE). Insomnia was studied in accordance with the criteria of the International Classification of Sleep ICDS‑22005. The quality of sleep was determined using a questionnaire from the Federal Somnological Center. Neuroimaging (MRI of the brain) was performed on Siemens Symphony 1.5 T and GE Signa 1.5 T tomographs.Results. Subjective symptoms CCI are characterized by a greater representation of asthenic and insomniac disorders. Transient ischemic attacks in patients with PV are significantly more common than in the comparison group, their frequency depends on the duration of PV. The revealed changes in MRI of the brain in the majority of PV patients with CCI are characteristic of multiinfarction vascular encephalopathy; in the comparison group, changes that characteristic for subcortical arteriosclerotic encephalopathy were more often recorded.


2018 ◽  
Vol 31 (08) ◽  
pp. 1171-1179 ◽  
Author(s):  
Shih-Feng Chen ◽  
Yu-Huei Chien ◽  
Pau-Chung Chen ◽  
I-Jen Wang

ABSTRACTBackground:The impact of age on the development of depression among patients with chronic kidney disease (CKD) at stages before dialysis is not well known. We aimed to explore the incidence of major depression among predialysis CKD patients of successively older ages through midlife.Methods:We conducted a retrospective cohort study using the longitudinal health insurance database 2005 in Taiwan. This study investigated 17,889 predialysis CKD patients who were further categorized into study (i.e. middle and old-aged) groups and comparison group aged 18–44. The International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) was applied for coding diseases.Results:The group aged 75 and over had the lowest (hazard ratio [HR] 0.47; 95% confidence interval [CI] 0.32–0.69) risk of developing major depression, followed by the group aged 65–74 (HR 0.67; 95% CI 0.49–0.92), using the comparison group as reference. The adjusted survival curves showed significant differences in cumulative major depression-free survival between different age groups. We observed that the risk of major depression development decreases with higher age. Females were at a higher risk of major depression than males among predialyasis CKD patients.Conclusions:The incidence of major depression declines with higher age in predialysis CKD patients over midlife. Among all age groups, patients aged 75 and over have the lowest risk of developing major depression. A female preponderance in major depression development is present. We suggest that depression prevention and therapy should be integrated into the standard care for predialysis CKD patients, especially for those young and female.


2017 ◽  
Vol 10 (2) ◽  
pp. 176
Author(s):  
Alexander Alekseevich Andreev ◽  
Anton Petrovich Ostroushko

Shamov, Vladimir Nikolaevich (1882-1962) – an outstanding Soviet surgeon, neurosurgeon, transfuziolog, academician of the USSR (1945), honored scientist of the RSFSR and the Ukrainian SSR, General-Lieutenant of medical service, laureate of the Lenin prize (1962); awarded the order of Lenin (twice), red banner (twice), red banner, red Star and medals of the USSR. Born may 22, 1882 in Menzelinsk, Ufa governorate (now Tatarstan). In 1908 he graduated from the Military medical Academy. In 1911 he defended his doctoral thesis on the topic: "the importance of physical methods for surgery of malignant tumors". From 1914 to 1923 V. N. Shamov – senior assistant in the Department of Fedorov. In 1919 he received isohemagglutinins serum for the determination of blood groups and for the first time the country produced a blood transfusion given group membership. In 1923, V. N. Shamov was elected as head of the Department of surgery of the Kharkov medical Institute and the surgical clinic of the Ukrainian Institute of experimental medicine. In 1926, he reported he developed a method of complete isolation from neural connections of the small intestine, derived under the skin, and transferring it to the blood supply of the subcutaneous vessels. In 1928, V. N. Shamov proposed and successfully conducted the transfusion of cadaveric blood. In 1930, he organized the second in the USSR and in the world Institute of blood transfusion and emergency surgery, and became its Director. In 1935 he was awarded the title of honored Worker of science. In the years 1939-1958 V. N. Shamov headed the Department of hospital surgery of the Military medical Academy, he was the scientific Director of the Leningrad Institute of blood transfusion (1939-1941). During world war II – General-Lieutenant of medical service, Deputy chief surgeon of the red Army, in 1945 – the chief surgeon of the Supreme command of the far Eastern front. In October 1945, he was elected a full member of the USSR AMS. Since 1947 – was also the Director of the Leningrad research neurosurgical Institute them. A. L. Polenov, surgeon-in-chief of the RSFSR. Since 1958 Professor-consultant of the Military medical Academy. In 1962, V. N. Shamov became a laureate of the Lenin prize for development and introduction in practice of the method of preparation and use fibrinoliticescoy blood. N. Shamov for the first time in the country performed periarterial sympathectomy and surgery choroidal plexuses of the ventricles of the brain; developed method pregrading plasty of the esophagus isolated loop of the small intestine, raised the question of limitation contraindications for surgical interventions in the elderly. He was one of the first applied with the purpose of anesthesia, controlled hypotension and hypothermia anesthesia gas nitrous oxide, etc.; successfully completed one-step pankreatoduodenektomiyu in pancreatic cancer; described the clinical picture of tumors of cortex and medulla of the adrenal glands. V.N. Shamov was a member of the Board of the all-Union society of surgeons and the International Association of surgeons, Chairman of the Surgical society. N.I.Pirogov, the Chairman of the organizing Bureau of the 24th all-Union Congress of surgeons, member of the scientific medical Council of Ministry of health of the USSR. More than 20 of his students became heads of departments of medical Universities. V. N. Shamov awarded the order of Lenin twice red banner (twice); the red banner of Labour, red Star, medals of the USSR. Died V.N. Shamov in Leningrad on 30 March 1962. In memory of academician V. N. The Shamov in St. Petersburg on the building of the Military medical Academy and Neurosurgical Institute. Professor A. L. Polenov installed a memorial plaque, a bust of Lieutenant General of medical service V. N. Shamova installed in the courtyard of the St. Petersburg blood transfusion center, one of the streets of the city of Menzelinsk were named after academician V. N. Shamova.


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