scholarly journals Best practices for Electronically Activated Recorder (EAR) research: A practical guide to coding and processing EAR data

2020 ◽  
Vol 52 (4) ◽  
pp. 1538-1551 ◽  
Author(s):  
Deanna M. Kaplan ◽  
Kelly E. Rentscher ◽  
Maximilian Lim ◽  
Ramon Reyes ◽  
Dylan Keating ◽  
...  
Author(s):  
Armita R Manafzadeh

Abstract X-Ray Reconstruction of Moving Morphology (XROMM), though traditionally used for studies of in vivo skeletal kinematics, can also be used to precisely and accurately measure ex vivo range of motion from cadaveric manipulations. The workflow for these studies is holistically similar to the in vivo XROMM workflow, but presents several unique challenges. This paper aims to serve as a practical guide by walking through each step of the ex vivo XROMM process: how to acquire and prepare cadaveric specimens, how to manipulate specimens to collect X-ray data, and how to use these data to compute joint rotational mobility. Along the way, it offers recommendations for best practices and for avoiding common pitfalls to ensure a successful study.


2021 ◽  
Vol 12 ◽  
Author(s):  
James W. Reinhardt ◽  
Christopher K. Breuer

Fibrocytes are hematopoietic-derived cells that directly contribute to tissue fibrosis by producing collagen following injury, during disease, and with aging. The lack of a fibrocyte-specific marker has led to the use of multiple strategies for identifying these cells in vivo. This review will detail how past studies were performed, report their findings, and discuss their strengths and limitations. The motivation is to identify opportunities for further investigation and promote the adoption of best practices during future study design.


2021 ◽  
Author(s):  
Joao Barbosa ◽  
Heike Stein ◽  
Christopher Summerfield ◽  
Salvador Soto-Faraco ◽  
Alexandre Hyafil

In the last few decades, the field of neuroscience has witnessed major technological advances that have allowed researchers to measure and control neural activity with great detail. Yet, behavioral experiments in humans remain an essential approach to investigate the mysteries of the mind. Their relatively modest technological and economic requisites make behavioral research an attractive and accessible experimental avenue for neuroscientists with very diverse backgrounds. However, like any experimental enterprise, it has its own inherent challenges that may pose practical hurdles, especially to less experienced behavioral researchers. Here, we aim at providing a practical guide for a steady walk through the workflow of a typical behavioral experiment with human subjects. This primer concerns the design of an experimental protocol, research ethics and subject care, as well as best practices for data collection, analysis, and sharing. The goal is to provide clear instructions for both beginners and experienced researchers from diverse backgrounds in planning behavioral experiments.


2021 ◽  
Author(s):  
Wei Wang ◽  
Thomas Mallouk

The recent invention of nanoswimmers– synthetic, powered objects with characteristic lengths in the range of 10-500 nm - has sparked widespread interest among scientists and the general public. As more researchers from different backgrounds enter the field, the study of nanoswimmers offers new opportunities but also significant experimental and theoretical challenges. In particular, the accurate characterization of nanoswimmers is often hindered by strong Brownian motion, convective effects, and the lack of a clear way to visualize them. When coupled with improper experimental designs and imprecise practices in data analysis, these issues can translate to results and conclusions that are inconsistent and poorly reproducible. This Perspective follows the course of a typical nanoswimmer investigation from synthesis through to applications and offers suggestions for best practices in reporting experimental details, recording videos, plotting trajectories, calculating and analyzing mobility, eliminating drift, and performing control experiments, in order to improve the reliability of the reported results.


2021 ◽  
Author(s):  
Wei Wang ◽  
Thomas Mallouk

The recent invention of nanoswimmers– synthetic, powered objects with characteristic lengths in the range of 10-500 nm - has sparked widespread interest among scientists and the general public. As more researchers from different backgrounds enter the field, the study of nanoswimmers gains new opportunities but also significant experimental and theoretical challenges. In particulr, the accurate characterization of nanoswimmers is often hindered by strong Brownian motion and the lack of a clear way to visualize them. When coupled with improper experimental design and imprecise practices in data analysis, these issues can translate to results and conclusions that are inconsistent and poorly reproducible. In light of the increasing popularity of nanoswimmer research and its challenges, we here offer suggestions of best practices for reporting and analyzing their movement. A particular emphasis is on the calculation and analysis of mean squared displacement, the key method for quantifying the mobility of a nanoswimmer. When applied carefully and systematically, the suggested practices can significantly improve the reliability of analyses and prevent embarrassing mistakes


Heart Rhythm ◽  
2018 ◽  
Vol 15 (9) ◽  
pp. 1348-1355 ◽  
Author(s):  
Wilber Su ◽  
Arash Aryana ◽  
Rod Passman ◽  
Gurjit Singh ◽  
Robert Hokanson ◽  
...  

2021 ◽  
pp. 191-222
Author(s):  
James E. Pfander

This chapter provides a primer on best practices in uncontested adjudication. Drawing lessons from the antebellum experience, the chapter reiterates the idea that important constitutional limits on federal adjudication—including the judicial finality requirement in Article III and the due process requirement of fair notice—fully apply to uncontested matters. The chapter further explains the importance of the judicial role in ensuring full development of the factual record in uncontested proceedings. The chapter explains how federal courts might best handle the uncontested adjudication of prisoner petitions through closer attention to the best practices outlined here. It concludes with a discussion of the federal judicial role in probate and domestic relations matters.


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