Copper-mediated arylation with arylboronic acids: Facile and modular synthesis of triarylmethanes
2016 ◽
Vol 12
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pp. 496-504
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A facile and modular synthesis of triarylmethanes was achieved in good yield via a two-step sequence in which the final step is the copper(II)-catalyzed arylation of diarylmethanols with arylboronic acids. By using this protocol a variety of symmetrical and unsymmetrical triarylmethanes were synthesized. As an application of the newly developed methodology, we demonstrate a high-yielding synthesis of the triarylmethane intermediate towards an anti-breast-cancer drug candidate.
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2021 ◽
Vol 39
(15_suppl)
◽
pp. e15069-e15069
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