scholarly journals CORRELATION BETWEEN PLASMATIC VITAMIN D LEVEL AND REFRACTIVE STATUS IN CHILDREN WITH DISABILITIES

2021 ◽  
Vol 70 (2) ◽  
pp. 129-134
Author(s):  
Larisa Bianca Holhoș ◽  
◽  
Teodora-Laura Holhoș ◽  
Mihaela Cristiana Coroi ◽  
Carina Petricău ◽  
...  
Keyword(s):  
Vitamin D ◽  
Children With Disabilities ◽  
Case Control Study ◽  
Refractive Errors ◽  
Retrospective Case ◽  
Disability Status ◽  
Refractive Status ◽  
Plasmatic Level ◽  
Age Range ◽  
Control Study

Introduction. Literature confirms that refractive errors are the most common, easily corrected, eye morbidity in children with disabilities. Early intervention such as wearing eyeglasses can positively impact the lives of these children. The implication of vitamin D status is investigated as a possible proactive measure in eye conditions. Aim. The current study proposed to asses the refractive status as well as vitamin D plasmatic level in 161 children. Another aim was to investigate whether myopia corelates with a lower plasmatic vitamin D level. Methods. A retrospective case-control study was done on 161 children, divided into two groups: the study group (children with disabilities) and the contol group (children without disabilities). The age range of children included in the study was from 5 to 16 years old. Results. Refractive errors were found to be more frequent in the group of children with disabilities and of these, astigmatism was the most frequent refractive disorder identified. Also, the plasmatic vitamin D level was found to be lower in those with myopia reguardless of disability status. Conclusions. Children with disabilities are diagnosed with refractive errors twice more frequenty than their healthy peers. Parents, medical staff and teachers should be aware of this risk factor and be more attentive because the presence of uncorrected refractive disorders may not be visible in most children, especially those with special needs.

scholarly journals Do Oral hygiene and Diet Favor The Development of Non-Carious Cervical Lesions? A Retrospective Study.

2021 ◽  
Author(s):  
Hector deLlanos-Lanchares ◽  
Leticia Alvarez-Menendez ◽  
Jose Antonio Alvarez-Riesgo ◽  
Alicia Celemin-Viñuela ◽  
Ildefonso Serrano-Belmonte ◽  
...  
Keyword(s):  
Case Control Study ◽  
Cervical Lesions ◽  
Treatment Needs ◽  
Retrospective Case ◽  
Predictive Capacity ◽  
Periodontal Index ◽  
Community Periodontal Index ◽  
Frequent Consumption ◽  
Age Range ◽  
Control Study

Abstract Purpose: The aim of this retrospective case-control study was to evaluate the influence of dental brushing factors, diet, the consumption of acidic drinks and Community Periodontal Index of Treatment Needs (CPITN) on the development of non-carious cervical lesions (NCCLs). Methods: The sample consisted of undergraduate dentistry students from different Spanish faculties (age range 18 to 29 years). NCCLs and the CPITN were diagnosed and recorded using a periodontal probe. A questionnaire was used to record different brushing factors, the consumption of extrinsic acids and the presence of intrinsic acids. The data obtained were analysed using unconditional uni- and multivariate logistic regression (significance lecel p<0.05). Results: Brushing force was a risk factor (OR=1.71). The presence of NCCLs is significantly more frequent in subjects who brush their teeth vigorously Frequent consumption of salads with vinegar or lemon increases the risk of NCCLs (OR=4.5). As the CPITN score increases, the risk of NCCLs also increases significantly (OR=1.93) for value 1 and OR=6.49 for CPITN of 3. The consumption of extrinsic acids associated with salads seasoned with vinegar or lemon, the brushing force and the CPITN were the risk factors. The model obtained has a 67.14% predictive capacity for NCCLs, a specificity of 76.43%, and a sensitivity of 57.86%. Conclusions: the results of this study show that brushing force, and acidic diet and CPITN significantly increase the risk of NCCLs. Other variables are needed to increase model prediction.

scholarly journals Vitamin D Deficiency in Non-Autoimmune Hypothyroidism: A case-control study

2020 ◽  
Author(s):  
Salma Ahi ◽  
Mohammad Reza Dehdar ◽  
Naser Hatami
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Case Control Study ◽  
Inverse Correlation ◽  
Case Control ◽  
Control Group ◽  
Retrospective Case ◽  
Autoimmune Hypothyroidism ◽  
Control Study

Abstract Objectives: Although in many studies, the relationship between autoimmune hypothyroidism (Hashimoto) and Vitamin D deficiency was shown, no research has been performed on the role of vitamin D in non-autoimmune hypothyroidism. Design: This was a Retrospective case–control study in Endocrinology clinic of Jahrom (south of Iran). The patients with Hashimoto (n=633) and non-Hashimoto hypothyroidism (n=305), along with a control group (n=200) were evaluated. 25(OH)D level, T3 and T4 levels were studied and Anti TPO and Anti TG tests were performed. The results of vitamin D level were analyzed and interpreted using SPSS in terms of the cause of hypothyroidism (immune and non-immune). Results: The results of the study showed a significantly lower level of vitamin D in both immune and non-immune Hashimoto’s thyroiditis (HT) in comparison to healthy controls (P<0.05). We observed a significant inverse correlation between the vitamin D and TGAb level (p=0.001, r=-0.261) and a direct correlation of vitamin D with TSH level (p=0.008, r=0.108) in HT patients. Conclusion: Finally, the results indicated that non-autoimmune hypothyroidism, as well as HT, is associated with vitamin D deficiency. The role of vitamin D deficiency in HT was thought to be in the association of higher autoantibody (TGAb) level; while, there should be further studies determining vitamin D deficiency's role in non-immune hypothyroidism.

scholarly journals Vitamin D Deficiency in Non-Autoimmune Hypothyroidism: A case-control study

2019 ◽  
Author(s):  
Salma Ahi ◽  
Mohammad Reza Dehdar ◽  
Naser Hatami
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Case Control Study ◽  
Inverse Correlation ◽  
Case Control ◽  
Control Group ◽  
Retrospective Case ◽  
Autoimmune Hypothyroidism ◽  
Control Study

Abstract Objectives: Although in many studies, the relationship between autoimmune hypothyroidism (Hashimoto) and Vitamin D deficiency was shown, no research has been performed on the role of vitamin D in non-autoimmune hypothyroidism. Design: This was a Retrospective case–control study in Endocrinology clinic of Jahrom (south of Iran). The patients with Hashimoto (n=633) and non-Hashimoto hypothyroidism (n=305), along with a control group (n=200) were evaluated. 25(OH)D level, T3 and T4 levels were studied and Anti TPO and Anti TG tests were performed. The results of vitamin D level were analyzed and interpreted using SPSS in terms of the cause of hypothyroidism (immune and non-immune). Results: The results of the study showed a significantly lower level of vitamin D in both immune and non-immune Hashimoto’s thyroiditis (HT) in comparison to healthy controls (P<0.05). We observed a significant inverse correlation between the vitamin D and TGAb level (p=0.001, r=-0.261) and a direct correlation of vitamin D with TSH level (p=0.008, r=0.108) in HT patients. Conclusion: Finally, the results indicated that non-autoimmune hypothyroidism, as well as HT, is associated with vitamin D deficiency. The role of vitamin D deficiency in HT was thought to be in the association of higher autoantibody (TGAb) level; while, there should be further studies determining vitamin D deficiency's role in non-immune hypothyroidism.

scholarly journals Comparison Of The 25oh-vitamin D Levels Between Old Patients Hospitalized For Sars-cov-2 Pneumonia And Patients With Other Acute Illnesses: A Retrospective Case-control Study.

2020 ◽  
Author(s):  
Luca Tomisti ◽  
Nicolò Pulizzi ◽  
Pia Clara Pafundi ◽  
Domenico Macaro ◽  
Liliana Villari ◽  
...  
Keyword(s):  
Vitamin D ◽  
Mortality Risk ◽  
Case Control Study ◽  
Case Control ◽  
Retrospective Case ◽  
Old Patients ◽  
Vitamin D Levels ◽  
25 Oh Vitamin D ◽  
Control Study ◽  
Group Serum

Abstract PURPOSE. To assess and compare the serum 25OH-vitamin D levels in three cohorts of patients hospitalized due to acute illness, either related or not to a SARS-COV-2 infection. To investigate, in the patients group with SARS-COV-2 pneumonia, the possible relationship between the serum vit- amin D levels and both disease severity and mortality risk.METHODS. This is a retrospective case-control study. Serum 25OH-vitamin D levels were compared between patients with SARS-COV-2 pneumonia (COVID-19 group, 52 patients), and two control groups, including patients with pneumonia not related to SARS-CoV-2 (NO COVID1 group, 52 patients) and patients with a non-respiratory acute disease (NO COVID2 group, 52 pa- tients).RESULTS. No differences were found in the serum 25 OH-Vitamin D levels among the three groups. In the COVID-19 group, serum 25 OH-Vitamin D levels did not show significant associa- tion with mortality risk (p=0.12), Intensive Care Unit admission risk (p=0.36), inpatients duration (p=0.40) and remission time (p=0.33). Similar results were found for parameters estimating the dis- ease severity, such as basal PO2/FiO2 (p=0.77), worse PO2/FiO2 (p=0.41), basal D-dimer (p=0.46) and basal LDH (p=0.52).CONCLUSIONS. Our data do not show lower 25OH-vitamin D levels in the patients with SARS- COV-2 pneumonia compared to patients hospitalized for other acute illnesses. In the COVID-19 group the 25OH-vitamin D levels did not show significant correlation with a worse outcome.

scholarly journals Vitamin D Deficiency in Non-Autoimmune Hypothyroidism: A case-control study

2020 ◽  
Author(s):  
Salma Ahi ◽  
Mohammad Reza Dehdar ◽  
Naser Hatami
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Case Control Study ◽  
Inverse Correlation ◽  
Case Control ◽  
Control Group ◽  
Retrospective Case ◽  
Autoimmune Hypothyroidism ◽  
Control Study

Abstract Objectives: Although in many studies, the relationship between autoimmune hypothyroidism (Hashimoto) and Vitamin D deficiency was shown, no research has been performed on the role of vitamin D in non-autoimmune hypothyroidism. Design: This was a Retrospective case–control study in Endocrinology clinic of Jahrom (south of Iran). The patients with Hashimoto (n=633) and non-Hashimoto hypothyroidism (n=305), along with a control group (n=200) were evaluated. 25(OH)D level, T3 and T4 levels were studied and Anti TPO and Anti TG tests were performed. The results of vitamin D level were analyzed and interpreted using SPSS in terms of the cause of hypothyroidism (immune and non-immune). Results: The results of the study showed a significantly lower level of vitamin D in both immune and non-immune Hashimoto’s thyroiditis (HT) in comparison to healthy controls (P<0.05). We observed a significant inverse correlation between the vitamin D and TGAb level (p=0.001, r=-0.261) and a direct correlation of vitamin D with TSH level (p=0.008, r=0.108) in HT patients. Conclusion: Finally, the results indicated that non-autoimmune hypothyroidism, as well as HT, is associated with vitamin D deficiency. The role of vitamin D deficiency in HT was thought to be in the association of higher autoantibody (TGAb) level; while, there should be further studies determining vitamin D deficiency's role in non-immune hypothyroidism.

scholarly journals Vitamin D deficiency is associated with higher hospitalisation risk from COVID-19: a retrospective case-control study

2021 ◽  
Author(s):  
Edward B Jude ◽  
Stephanie F Ling ◽  
Rebecca Allcock ◽  
Beverly X Y Yeap ◽  
Joseph M Pappachan
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Case Control Study ◽  
Case Control ◽  
Normal Serum ◽  
Retrospective Case ◽  
Median Serum ◽  
Hospitalised Patients ◽  
Vitamin D Levels ◽  
Control Study

Abstract CONTEXT One of the risk factors for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is postulated to be vitamin D deficiency. To understand better the role of vitamin D deficiency in the disease course of COVID-19, we undertook a retrospective case-control study in the North West of England (NWE). OBJECTIVE To examine whether hospitalisation with COVID-19 is more prevalent in individuals with lower vitamin D levels. METHODS The study included individuals with results of serum 25-hydroxyvitamin D (25[OH]D) between 1 st April 2020 and 29th January 2021. Patients were recruited from two districts in NWE. The last 25(OH)D level in the previous 12 months was categorised as ‘deficient’ if less than 25 nmol/L and ‘insufficient’ if 25-50 nmol/L. RESULTS 80,670 participants were entered into the study. Of these, 1,808 were admitted to hospital with COVID-19, of whom 670 died. In a primary cohort, median serum 25(OH)D in participants who were not hospitalised with COVID-19 was 50.0 [interquartile range, IQR 34.0-66.7] nmol/L versus 35.0 [IQR 21.0-57.0] nmol/L in those admitted with COVID-19 (p &lt;0.005). There were similar findings in a validation cohort (median serum 25(OH)D 47.1 [IQR 31.8-64.7] nmol/L in non-hospitalised versus 33.0 [IQR 19.4-54.1] nmol/L in hospitalised patients). Age-, sex- and seasonal variation-adjusted odds ratios for hospital admission were 2.3-2.4 times higher among participants with serum 25(OH)D &lt;50 nmol/L, compared to those with normal serum 25(OH)D levels, without any excess mortality risk. CONCLUSIONS Vitamin D deficiency is associated with higher risk of COVID-19 hospitalisation. Widespread measurement of serum 25(OH)D and treating any unmasked insufficiency or deficiency through testing may reduce this risk.

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