scholarly journals Features of vasoregulatory function of vascular endothelium and correlations between them, hemodynamic and metabolic parameters in patients with coronary heart disease and type 2 diabetes mellitus

2021 ◽  
pp. 28-30
Author(s):  
О. О. Pogrebniak
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Vascular Endothelium ◽  
Type Ii Diabetes ◽  
Glycosylated Hemoglobin ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii ◽  
Very Low Density Lipoproteins ◽  
Fasting Glycemia

The features of the vasoregulating function of the vascular endothelium have been determined and correlations between haemodynamic and metabolic indices have been established in patients with coronary heart disease associated with type II diabetes mellitus. In patients with coronary heart disease associated with type II diabetes mellitus in comparison with patients without an association with diabetes mellitus significantly higher indices of the content of the blood fibrinogen the diameter of the brachial artery (after decompression) were observed. Direct correlations between fasting glycemia and microalbuminuria and reverse correlations with the endothelial dependent vasodilatation (EDVA), fasting glucemia, the blood content of glycosylated hemoglobin and very low density lipoproteins have been found.

Adherence to clinical guidelines in the prevention of coronary heart disease in type II diabetes mellitus

2007 ◽  
Vol 30 (1) ◽  
pp. 120-127 ◽  
Author(s):  
Majidreza Kamyar ◽  
B. Julienne Johnson ◽  
John J. McAnaw ◽  
Rosa Lemmens-Gruber ◽  
Steve A. Hudson
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Clinical Guidelines ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii

scholarly journals Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Marouane Boukhris ◽  
Salvatore Davide Tomasello ◽  
Francesco Marzà ◽  
Sonia Bregante ◽  
Francesca Romana Pluchinotta ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Type Ii Diabetes ◽  
Estrogen Replacement Therapy ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii ◽  
Estrogen Replacement ◽  
The Impact

Coronary heart disease is the main cause of death in postmenopausal women (PMW); moreover its mortality exceeds those for breast cancer in women at all ages. Type II diabetes mellitus is a major cardiovascular risk factor and there is some evidence that the risk conferred by diabetes is greater in women than in men. It was established that the deficiency of endogenous estrogens promotes the atherosclerosis process. However, the impact of estrogen replacement therapy (ERT) on cardiovascular prevention remains controversial. Some authors strongly recommend it, whereas others revealed a concerning trend toward harm. This review tries to underlines the different components of cardiovascular risk in diabetic PMW and to define the place of ERT.

scholarly journals Risk factors for coronary heart disease in type II diabetes mellitus

2005 ◽  
Vol 20 (2) ◽  
pp. 75-80 ◽  
Author(s):  
H. Surekha Rani ◽  
G. Madhavi ◽  
V. Ramachandra Rao ◽  
B. K. Sahay ◽  
A. Jyothy
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii

scholarly journals Obesity. An imbalance of energy or an imbalance of nutrients?

1997 ◽  
Vol 43 (5) ◽  
pp. 47-50
Author(s):  
M. M. Ginzburg ◽  
G. S. Kozupitsa
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Heart Disease ◽  
Type Ii Diabetes ◽  
Developed Countries ◽  
Type Ii Diabetes Mellitus ◽  
Common Disease ◽  
Type Ii ◽  
Current State ◽  
Prevention Therapy ◽  
And Control

Obesity is now the most common disease in the population of economically developed countries, where up to 25% of residents have a body weight that is more than 15% higher than normal [8]. An increase in the incidence rate of about 10% over 10 years is observed [33]. The causal relationship between obesity and arterial hypertension, coronary heart disease, and type II diabetes mellitus is well known [6, 10]. At the same time, the current state of the problem of prevention, therapy and control of relapse of obesity is far from perfect. And this is primarily due to the fact that we do not fully know the pathogenesis of this disease.

scholarly journals Serum chromium, glycosylated hemoglobin level and body mass index among control and uncontrol sudanese patients with type II diabetes mellitus: Correlation study

2021 ◽  
Vol 16 (2) ◽  
pp. 196-203
Author(s):  
Nassr Eldin M. A. shrif ◽  
Ahmed Mohamed Ahmed Dawood ◽  
Abdelmahmoud Mokhtar Bashir ◽  
Hassan Mohammed Khair Ibrahim ◽  
Abd Elgadir A Altoum
Keyword(s):  
Diabetes Mellitus ◽  
Type Ii Diabetes ◽  
Glycosylated Hemoglobin ◽  
Type Ii Diabetes Mellitus ◽  
P Value ◽  
Diabetic Patients ◽  
Type Ii ◽  
Chromium Level ◽  
Serum Chromium ◽  
R Value

Background: Chromium is an essential micronutrient which is required for the normal functioning of insulin and regulation of blood sugar levels. It acts as a vital antioxidant for maintaining insulin homeostasis. In diabetes mellitus, the free radical production is increased and levels of antioxidants like chromium, vanadium, selenium and manganese are reduced. Aim: To study the level of serum chromium level in patients with type 2 diabetes mellitus and its association with glycemic control. Materials and Methods: One hundred and twenty individuals were enrolled in this study, classified into 60 type II diabetes mellitus (type II DM) patients and 60 apparently health as control group. Serum chromium and Glycosylated Hemoglobin (HbA1c) level were measured using atomic absorption spectrometry and Ichroma. Results: The results showed significant decrease in serum chromium level in type II DM patients (0.0151±0.005) when compared with healthy group (0.122±0.691) with p-value (0.002). In addition to that there was significant decrease in mean concentration of serum chromium level in controlled diabetic patients (0.0206± 0.003) when compared with uncontrolled diabetic patients (0.0120±0.002) with P-value (0.04).Also there was significant positive correlation between chromium level and Body Mass Index (BMI) (R-value 0.450, P-value 0.014), and significant negative correlation between chromium level and age (R-value- 0.660, P-value 0.011) , a significant strong negative correlation between chromium level and HbA1c (R-value -0.843, P-value 0.0260). Conclusion: The study concluded that, serum chromium level is significantly decrease in type II DM.

GLYCOSYLATED HEMOGLOBIN IN THE DIAGNOSIS AND CONTROL OF TYPE II DIABETES MELLITUS

Vestnik ◽  
2021 ◽  
pp. 173-178
Author(s):  
М.А. Дуйсекова ◽  
Д. Алимова ◽  
А.С. Айткулова ◽  
А. Райымжанкызы ◽  
Д.Б. Ногайбай ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type Ii Diabetes ◽  
Glycosylated Hemoglobin ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii ◽  
Wide Range ◽  
Impaired Insulin ◽  
Hypoglycemic Therapy ◽  
And Control

Сахарный диабет характеризуется нарушением секреции инсулина и той или иной степенью инсулинорезистентности, обусловливающими гипергликемию. Диабет в 2 раза повышает риски появления широкого спектра сердечно-сосудистых заболеваний, в 6 раз повышает риски ИБС. ХБП развивается примерно у 35% пациентов с сахарным диабетом II типа и ассоциирован с повышенной смертностью. В Казахстане исследования на эту тему проведены не были. Уровень гликозилированного гемоглобина отражает состояние компенсации углеводного обмена, показывает эффективность сахароснижающей терапии и определяет стратегию лечения пациента. Diabetes mellitus is characterized by impaired insulin secretion and varying degrees of insulin resistance, causing hyperglycemia. Diabetes increases the risk of a wide range of cardiovascular diseases by 2 times, and increases the risk of CHD by 6 times. CKD develops in approximately 35% of patients with type II diabetes and is associated with increased mortality. No studies on this topic have been conducted in Kazakhstan. The level of glycosylated hemoglobin reflects the state of carbohydrate metabolism compensation, shows the effectiveness of hypoglycemic therapy and determines the patient's treatment strategy.

scholarly journals Silymarin, Olibanum, and Nettle, A Mixed Herbal Formulation in the Treatment of Type II Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Clinical Trial

2017 ◽  
Vol 22 (4) ◽  
pp. 603-608 ◽  
Author(s):  
Nahid Khalili ◽  
Reza Fereydoonzadeh ◽  
Reza Mohtashami ◽  
Saeed Mehrzadi ◽  
Mojtaba Heydari ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Clinical Trial ◽  
Type Ii Diabetes ◽  
Glycosylated Hemoglobin ◽  
Fasting Blood Glucose ◽  
Type Ii Diabetes Mellitus ◽  
Controlled Clinical Trial ◽  
Type Ii ◽  
Double Blind ◽  
Herbal Formulation

Silybum marianum (L) Gaertn (milk thistle) seeds, Urtica dioica L (nettle) leaves, and Boswellia serrata (olibanum gum) resin are used traditionally by Iranian diabetic patients. The aim of this study was to evaluate the antihyperglycemic effects of these herbs in an herbal formulation in patients with type II diabetes mellitus. Sixty patients diagnosed as type II diabetes mellitus with fasting blood glucose level from 150 to 180 mg/dL, glycosylated hemoglobin level from 7.5% to 8.5%, and on oral antihyperglycemic drugs, were allocated to receive the mix herbal formulation or placebo for 90 days in a double-blind randomized placebo-controlled clinical trial. The mean serum fasting blood glucose, glycosylated hemoglobin, and triglyceride in the herbal drug group were significantly less than placebo group’s values after 3 months of the intervention. The study showed a potential antihyperglycemic and triglyceride lowering effect of the herbal formulation, while it did not have any significant cholesterol or blood pressure lowering effect.

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