scholarly journals Nghiên cứu đặc điểm lâm sàng và cận lâm sàng bệnh schonlein-henoch ở trẻ em

2020 ◽  
Author(s):  
Hùng Việt Phan
Keyword(s):  
Age Of Onset ◽  
University Hospital ◽  
Renal Lesion ◽  
Henoch Schonlein Purpura ◽  
Cross Sectional ◽  
Kidney Lesion ◽  
High Erythrocyte Sedimentation Rate ◽  
The Relationship ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Study clinical and subclinical features of Henoch-Schönlein purpura in children Objective: Describe clinical and subclinical characteristics of Henoch-Schönlein purpura in children. Find the relationship between kidney lesion and clinical and subclinical manifestations. Methods: Cross-sectional descriptive study, including 51 children <15 years of age diagnosed with Schonlein-Henoch purpura being treated at Hue Central Hospital and Hue University Hospital from April 2016 - May 2018. Results: 51 children entered the study: Male:Female =1.3:1; mean age 7.5  3.4 years. At onset, purpura was present in all cases, gastrointestinal manifestations in 66.7%, arthritis/arthralgias in 54.9%, , renal lesion in 19.6%. The most frequent laboratory abnormalities were Leukocytosis (WBC >10 x 109/L) in 60,8%, high-erythrocyte sedimentation rate (ESR) in 80.4%, microscopic hematuria in 15.7%, proteinuria in 13.7%. Renal lesion were correlated with age of onset. The age group> 10 years old has 6.1 times more kidney lesion than the group ≤ 10 years (OR: 6.1; 95% CI (1.5-26). Conclusion: Clinical and subclinical findings of Schonlein-Henoch purpura in our study are similar to those in the literature. There is an relationship between the age of onset with kidney lesion. Key words: Henoch-Schönlein purpura, kidney lesion

scholarly journals HENOCH-SCHONLEIN PURPURA IN CHILDREN: A CROSS SECTIONAL STUDY

2019 ◽  
Vol 6 (3) ◽  
pp. 99-103
Author(s):  
Fatih Karaaslan ◽  
Betul Gemici Karaaslan ◽  
Huseyin Dag ◽  
Soner Sazak ◽  
Emine Turkkan ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Sectional Study ◽  
Henoch Schonlein Purpura ◽  
Cross Sectional ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

scholarly journals The Relationship Between Sonographic Findings, and Clinical and Paraclinical Symptoms in Henoch Schonlein Purpura

2017 ◽  
Vol 27 (2) ◽  
Author(s):  
Houman Alizadeh ◽  
Mojtaba Ranjbar ◽  
Vahid Ziaee ◽  
Reihaneh Mohsenipour ◽  
Mehrzad Mehdizadeh ◽  
...  
Keyword(s):  
Henoch Schonlein Purpura ◽  
The Relationship ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

scholarly journals Age of onset as a risk factor of renal involvement in Henoch-Schönlein purpura

2014 ◽  
Vol 4 (1) ◽  
pp. 42 ◽  
Author(s):  
Reni Ghrahani ◽  
Masayu Amanda Ledika ◽  
Gartika Sapartini ◽  
Budi Setiabudiawan
Keyword(s):  
Risk Factor ◽  
Age Of Onset ◽  
Renal Involvement ◽  
Henoch Schonlein Purpura ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

scholarly journals HENOCH-SCHÖNLEIN PURPURA NEPHRITIS IN CHILDREN: EXPERI-ENCE OF THE TWO TERTIARY CARE CENTERS FOR PEDIATRIC AND ADOLESCENT RHEUMATOLOGY OF THE REPUBLIC OF CROATIA FROM 2006 TO 2017

2018 ◽  
Vol 141 (5-6) ◽  
pp. 115-126
Keyword(s):  
Kidney Disease ◽  
Tertiary Care ◽  
University Hospital ◽  
Henoch Schonlein Purpura ◽  
Renal Complications ◽  
Number Of Patients ◽  
Isolated Proteinuria ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura ◽  
Purpura Nephritis

Aim: To determine types of renal complications, indications for biopsy, treatment methods and possible outcomes in patients with Henoch-Schönlein purpura nephritis. Patients and methods: Retrospective analysis of medical data of HSP patients treated at the Department of Paediatrics, University Hospital Centre Zagreb, and the Department of Paediatrics, University Hospital Centre Split, during the period from 2006 to 2017, who developed kidney disease according to EULAR/PRINTO/PRES criteria. Results: Out of 378 patients diagnosed with HSP, 81 (21.4%) developed kidney disease, out of whom 43 boys (53.1%) and 38 girls (46.9%), with the median age 8.4 years (2.5–16.8).. A statistically significant increase of patients with HSP was during autumn and winter. There is a greater chance of nephritis with the increase of patients age at diagnosis. For every year (from 1 to 17 years) the chances increase by around 2.25%. Equal number of patients, 44.45%, had both hematuria and proteinuria or isolated hematuria, and only 11.1% isolated proteinuria. Renal biopsy was performed in 37 patients (45.7%), and most biopted patients were from concurrent hematuria and proteinuria group (70.3%). Children with isolated hematuria or with isolated proteinuria were most often treated with corticosteroids while children with hematuria and proteinuria were most often treated with corticosteroids and angiotensin-converting enzyme inhibitors. Immunosuppressives were used in 16% of the patients, including most of those in the group with concurrent hematuria and proteinuria (69.2%). Only one patient (1.2%) developed renal insufficiency with the need for dialysis, while the outcome of the others was evaluated as good. Conclusion: Renal complications are the most important factor in the outcome of patients with HSP. For the optimal treatment of these patients it is necessary to bring consensus about the indications for kidney biopsy in HSP, and also to validate the existing pathohistological classification to affirm which one best correlates with the adverse outcome of the disease.

scholarly journals Sonographic Findings of Arthralgia in Children with Henoch-Schönlein Purpura

2020 ◽  
Author(s):  
Ji Hyun Seo ◽  
Min-Ji Kim ◽  
Jae-Min Cho ◽  
Jae Boem Na ◽  
Jae Young Kim ◽  
...  
Keyword(s):  
Limited Range ◽  
University Hospital ◽  
Joint Effusion ◽  
Henoch Schonlein Purpura ◽  
Limited Range Of Motion ◽  
Subcutaneous Edema ◽  
National University ◽  
Us Findings ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Abstract Background Arthralgia is a common manifestation in children with Henoch–Schönlein purpura (HSP). No ultrasonographic (US) findings of arthralgia in patients with HSP have been reported. We therefore investigated these findings in affected joints of children with HSP. Methods The medical records of patients with HSP and arthralgia at Gyeongsang National University Hospital from 2014 to 2018 were reviewed for clinical data about arthralgia, anatomic location, US findings, treatment, and duration of improvement. Results Thirty-one patients underwent joint US imaging. Sixteen patients (51.6%) were aged 2–5 y, 10 (32.3%) were aged 6–10 y, and 5 (16.1%) were aged 11–17 y. Nineteen (61.3%) were boys and 12 (38.7%) were girls. The joint most commonly affected was the ankle (n = 25), followed by the knee (n = 6) and the foot or elbow. Four patients complained of knee and ankle pain simultaneously. Swelling, limited range of motion, tenderness, erythema, and febrile sensation in affected joints were observed in 22 patients (71.0%), 9 (29.0%), 21 (67.7%), 25 (80.6%), and 6 (19.4%), respectively. US images showed no visible joint effusion and no evidence of arthritis or synovitis, but it did show subcutaneous swelling with increased echo around affected joints. Arthralgia improved spontaneously in 6 patients and with corticosteroids in 25. Improvement in arthralgia lasted a mean of 1.9 ± 1.8 days. Conclusion US images showed subcutaneous edema around joints with neither joint effusion nor synovial inflammation.

scholarly journals Clinicopathological features of pediatric renal biopsies in the plateau regions of China

2018 ◽  
Vol 46 (11) ◽  
pp. 4539-4546 ◽  
Author(s):  
Nini Wang ◽  
Tingting Zhu ◽  
Yuhong Tao
Keyword(s):  
Kidney Diseases ◽  
Clinicopathological Features ◽  
University Hospital ◽  
Henoch Schonlein Purpura ◽  
B Virus ◽  
Renal Biopsies ◽  
Primary Glomerular Disease ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura ◽  
Purpura Nephritis

Objective This study aimed to analyze the clinicopathological features of pediatric renal biopsies from plateau regions of China. Methods Clinicopathological features of pediatric renal biopsies were compared between plateau and non-plateau regions in patients who were admitted to West China Second University Hospital, Sichuan University between April 2001 and March 2017. Patients were children younger than 18 years. Results The proportion of primary glomerular disease in the plateau group was lower than that in the non-plateau group (45.56% vs 62.09%, respectively). In the plateau group, IgA nephropathy (IgAN) was the major primary glomerulonephritis (GN) pathology. IgAN accounted for 36.54% and 21.63% of GN cases with nephrotic syndrome and hematuria, respectively. Henoch-Schönlein purpura nephritis was the most common secondary GN in both groups. The proportion of hepatitis B virus-associated GN was higher and that of lupus nephritis was lower in the plateau group than in the non-plateau group. Conclusions There are differences in renal pathological types between children in plateau regions and those in non-plateau regions. Among children in plateau regions, IgAN and Henoch-Schönlein purpura nephritis were the most common kidney diseases.

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