Flavone from the Lycopersicon esculentum and their antioxidant capacity through GSH recovery effect

Aims: This study is to ascertain nutrient content and antioxidant compounds of four varieties of Lycopersicon esculentum Mill. (UC82b, Amiral F1, Local cotelette and Local cerise) grown in Cote d’Ivoire. Study Design: This study is to assess the nutritional and antioxidant value of tomatoes (Lycopersicon esculentum Mill.) grown in Cote d’Ivoire in order to know if they can help to prevent against oxidative stress. Place and duration of Study: Four ripe tomato varieties were collected from different tomato fields in Yamoussoukro district (Cote d'Ivoire) during season from December 2016 to January 2017. The determination of nutrient content and antioxidant compounds were ascertained at the LAPISEN of INPHB (Yamoussoukro). Methodology: Macronutrient and micronutrient of the four tomato varieties collected were determinate. Then, lycopene, polyphenol and flavonoid contents were assessed. The antioxidant capacity of tomato extracts was evaluated using DPPH method. Results: Among the varieties studied, Amiral F1 has the highest antioxidant capacity with an EC50 of 3.47 mg/mL and the highest total polyphenol content (17.5 mg/100 g EAG of fw). Local cotelette variety is the richest in lycopene (2.9 mg/100 g of fw) and vitamin C (35.4 mg/100 g of fw). In addition, this variety also has the highest levels of calcium (31 mg/100 g of fw), magnesium (21 mg/100 g of fw) and potassium (333 mg/100 g of fw). UC82b is the best source of iron (0.065 mg/100 g of fw), phosphorus (23 mg/100 g of fw), manganese (0.086 mg /100 g of fw) and zinc (0 11 mg/100 g of fw). Conclusion: This investigation showed that the different studied varieties of tomato possessed high antioxidant capacities. As a result, they could be used to fight against oxidative stress.

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Trans-resveratrol supplement lowers lipid peroxidation responses of exercise in male Wistar rats

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000654 ◽

2020 ◽

pp. 1-6 ◽

Cited By ~ 1

Author(s):

Masoud Nasiri ◽

Saja Ahmadizad ◽

Mehdi Hedayati ◽

Tayebe Zarekar ◽

Mehdi Seydyousefi ◽

...

Keyword(s):

Lipid Peroxidation ◽

Antioxidant Capacity ◽

Total Antioxidant Capacity ◽

Wistar Rats ◽

Enzymatic Antioxidants ◽

Acute Response ◽

Total Antioxidant ◽

Male Wistar Rats ◽

Exercise Induced ◽

And Control

Abstract. Physical exercise increases free radicals production; antioxidant supplementation may improve the muscle fiber’s ability to scavenge ROS and protect muscles against exercise-induced oxidative damage. This study was designed to examine the effects of all-trans resveratrol supplementation as an antioxidant to mediate anti-oxidation and lipid per-oxidation responses to exercise in male Wistar rats. Sixty-four male Wistar rats were randomly divided into four equal number (n = 16) including training + supplement (TS), training (T), supplement (S) and control (C) group. The rats in TS and S groups received a dose of 10 mg/kg resveratrol per day via gavage. The training groups ran on a rodent treadmill 5 times per week at the speed of 10 m/min for 10 min; the speed gradually increased to 30 m/min for 60 minutes at the end of 12th week. The acute phase of exercise protocol included a speed of 25 m/min set to an inclination of 10° to the exhaustion point. Superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT) activity, non-enzymatic antioxidants bilirubin, uric acid, lipid peroxidation levels (MDA) and the total antioxidant capacity (TAC) were measured after the exercise termination. The data were analyzed by using one-way ANOVA. The result showed that endurance training caused a significant increase in MDA level [4.5 ± 0.75 (C group) vs. 5.9 ± 0.41 nmol/l (T group)] whereas it decreased the total antioxidant capacity [8.5 ± 1.35 (C group) vs. 7.1 ± 0.55 mmol/l (T group)] (p = 0.001). In addition, GPx and CAT decreased but not significantly (p > 0.05). The training and t-resveratrol supplementation had no significant effect on the acute response of all variables except MDA [4.3 ± 1.4 (C group) vs. 4.0 ± 0.90 nmol/l (TS group)] (p = 0.001) and TAC [8.5 ± 0.90 (C group) vs. 6.6 ± 0.80 mmol/l (TS group)] (p = 0.004). It was concluded that resveratrol supplementation may prevent exercise-induced oxidative stress by preventing lipid peroxidation.

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The Role of Polyphenols in the Modulation of Plasma Non-Enzymatic Antioxidant Capacity (NEAC)

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000116 ◽

2012 ◽

Vol 82 (3) ◽

pp. 228-232 ◽

Cited By ~ 7

Author(s):

Mauro Serafini ◽

Giuseppa Morabito

Keyword(s):

Antioxidant Capacity ◽

Dietary Intervention ◽

Ex Vivo ◽

The Body ◽

Dietary Polyphenols ◽

Enzymatic Antioxidant ◽

Endogenous Antioxidant

Dietary polyphenols have been shown to scavenge free radicals, modulating cellular redox transcription factors in different in vitro and ex vivo models. Dietary intervention studies have shown that consumption of plant foods modulates plasma Non-Enzymatic Antioxidant Capacity (NEAC), a biomarker of the endogenous antioxidant network, in human subjects. However, the identification of the molecules responsible for this effect are yet to be obtained and evidences of an antioxidant in vivo action of polyphenols are conflicting. There is a clear discrepancy between polyphenols (PP) concentration in body fluids and the extent of increase of plasma NEAC. The low degree of absorption and the extensive metabolism of PP within the body have raised questions about their contribution to the endogenous antioxidant network. This work will discuss the role of polyphenols from galenic preparation, food extracts, and selected dietary sources as modulators of plasma NEAC in humans.

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