scholarly journals Risk factors of severe hand, foot and mouth disease in Shantou, China: a case-control study

2018 ◽  
Vol 12 (05) ◽  
pp. 359-364
Author(s):  
Chunhua Liu ◽  
Kaiyan Wang ◽  
Niyang Lin ◽  
Jianling Cai ◽  
Binglin Cui ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Temperature ◽  
Case Control Study ◽  
Total Duration ◽  
Foot And Mouth Disease ◽  
Case Control ◽  
Mouth Disease ◽  
Ev71 Infection ◽  
Independent Risk Factors ◽  
Control Study

Introduction: In clinical perspectives, how to distinguish a small proportion of children at risk of developing neurological complications from a large number of children with mild symptoms still remains a challenge for primary care doctors. Methodology: From January 2012 to December 2015, 225 cases with severe hand, foot and mouth disease (HFMD) matched with 492 controls were enrolled in the age-matched, case-control study. Continuous variables were examined by univariate analysis using a chi-squared or Fisher’s exact test, and categorical variables were reported by relative risks (odd’s ratio). Multivariate logistic regression was used to analyze the independent risk factors for severe HFMD. Results: Peak body temperature over 37.5℃，total duration of fever over 3 days, lethargy, enterovirus 71 (EV71) infection were independent risk factors for severe HFMD. Conclusions: Peak body temperature over 37.5℃，total duration of fever over 3 days, lethargy, EV71 infection were independent risk factors for severe HFMD.

scholarly journals Risk factors for the transmission of foot-and-mouth disease during the 2010 outbreak in Japan: a case--control study

2013 ◽  
Vol 9 (1) ◽  
pp. 150 ◽  
Author(s):  
Norihiko Muroga ◽  
Sota Kobayashi ◽  
Takeshi Nishida ◽  
Yoko Hayama ◽  
Takaaki Kawano ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Foot And Mouth Disease ◽  
Case Control ◽  
Mouth Disease ◽  
Foot And Mouth ◽  
Control Study

Risk factors for severe hand, foot, and mouth disease infected with Coxsackievirus A6: A hospital‐based case‐control study

2020 ◽  
Vol 92 (12) ◽  
pp. 3144-3150 ◽  
Author(s):  
Yanan Li ◽  
Tiantian Xiong ◽  
Yu Meng ◽  
Rongxian Zhao ◽  
Guangqing Yu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Foot And Mouth Disease ◽  
Case Control ◽  
Mouth Disease ◽  
Coxsackievirus A6 ◽  
Foot And Mouth ◽  
Control Study

scholarly journals A Case-control Study on Risk Factors for Severe Hand, Foot and Mouth Disease

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Dingmei Zhang ◽  
Ruolin Li ◽  
Wangjian Zhang ◽  
Guowei Li ◽  
Zhanzhong Ma ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Foot And Mouth Disease ◽  
Case Control ◽  
Mouth Disease ◽  
Foot And Mouth ◽  
Control Study

Carbapenem-ResistantKlebsiella pneumoniaein Post-Acute-Care Facilities in Israel

2011 ◽  
Vol 32 (9) ◽  
pp. 845-853 ◽  
Author(s):  
Debby Ben-David ◽  
Samira Masarwa ◽  
Shiri Navon-Venezia ◽  
Hagit Mishali ◽  
Ilan Fridental ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Care ◽  
Case Control Study ◽  
Case Control ◽  
Antibiotic Exposure ◽  
Care Facilities ◽  
History Of ◽  
Independent Risk Factors ◽  
Acute Care Facilities ◽  
Control Study

Objective.To assess the prevalence of and risk factors for carbapenem-resistantKlebsiella pneumoniae(CRKP) carriage among patients in post-acute-care facilities (PACFs) in Israel.Design, Setting, and Patients.A cross-sectional prevalence survey was conducted in 12 PACFs. Rectal swab samples were obtained from 1,144 patients in 33 wards. Risk factors for CRKP carriage were assessed among the cohort. Next, a nested, matched case-control study was conducted to define individual risk factors for colonization. Finally, the cohort of patients with a history of CRKP carriage was characterized to determine risk factors for continuous carriage.Results.The prevalence of rectal carriage of CRKP among 1,004 patients without a history of CRKP carriage was 12.0%. Independent risk factors for CRKP carriage were prolonged length of stay (odds ratio [OR], 1.001;P< .001), sharing a room with a known carrier (OR, 3.09;P= .02), and increased prevalence of known carriers on the ward (OR, 1.02;P= .013). A policy of screening for carriage on admission was protective (OR, 0.41;P= .03). Risk factors identified in the nested case-control study were antibiotic exposure during the prior 3 months (OR, 1.66;P= .03) and colonization with other resistant pathogens (OR, 1.64;P= .03). Among 140 patients with a history of CRKP carriage, 47% were colonized. Independent risk factors for continued CRKP carriage were antibiotic exposure during the prior 3 months (OR, 3.05;P= .04), receipt of amoxicillin-clavulanate (OR, 4.18;P= .007), and screening within 90 days of the first culture growing CRKP (OR, 2.9;P= .012).Conclusions.We found a large reservoir of CRKP in PACFs. Infection-control polices and antibiotic exposure were associated with patient colonization.

scholarly journals Scavenger receptor class a, member 3 is associated with severity of hand, foot, and mouth disease in a case-control study

Medicine ◽  
2019 ◽  
Vol 98 (40) ◽  
pp. e17471
Author(s):  
Ye Tian ◽  
Kai Zhou ◽  
Jing Hu ◽  
Ming-Feng Shan ◽  
Hong-Jian Chen ◽  
...  
Keyword(s):  
Case Control Study ◽  
Scavenger Receptor ◽  
Foot And Mouth Disease ◽  
Case Control ◽  
Mouth Disease ◽  
Class A ◽  
Scavenger Receptor Class ◽  
Foot And Mouth ◽  
Control Study

scholarly journals Investigating the Synergistic Interaction of Diabetes, Tobacco Smoking, Alcohol Consumption, and Hypercholesterolemia on the Risk of Pancreatic Cancer: A Case-Control Study in Italy

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Giuseppe La Torre ◽  
Antonella Sferrazza ◽  
Maria Rosaria Gualano ◽  
Chiara de Waure ◽  
Gennaro Clemente ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pancreatic Cancer ◽  
Alcohol Consumption ◽  
Case Control Study ◽  
Smoking Status ◽  
Conditional Logistic Regression ◽  
Case Control ◽  
Synergistic Interaction ◽  
Independent Risk Factors ◽  
Control Study

The aims of the present research are to investigate the possible predictors of pancreatic cancer, in particular smoking status, alcohol consumption, hypercholesterolemia, and diabetes mellitus, in patients with histologically confirmed pancreatic carcinoma and to examine the synergism between risk factors. A case-control study (80 patients and 392 controls) was conducted at the Teaching Hospital “Agostino Gemelli” in Rome. A conditional logistic regression was used for the statistical analysis and results were presented as odds ratio (OR) and 95% confidence intervals (95% CI). We also investigated the possible interactions between risk factors and calculated the synergism index (SI). The multivariate analysis revealed that hypercholesterolemia and alcohol consumption resulted in important risk factors for pancreatic cancer even after the adjustment for all variables (OR: 5.05, 95% CI: 2.94–8.66; OR: 2.25, 95% CI: 1.30–3.89, resp.). Interestingly, important synergistic interactions between risk factors were found, especially between ever smoking status and alcohol consumptions (SI = 17.61) as well as alcohol consumption and diabetes (SI = 17.77). In conclusion, the study confirms that hypercholesterolemia and alcohol consumption represent significant and independent risk factors for pancreatic cancer. Moreover, there is evidence of synergistic interaction between diabetes and lifestyle factors (drinking alcohol and eating fatty foods).

Increasing Incidence and Recurrence Rate of Venous Thromboembolism in Paediatric Oncology Patients in One Single Centre Over 25 Years

2017 ◽  
Vol 117 (11) ◽  
pp. 2156-2162 ◽  
Author(s):  
Irene Klaassen ◽  
Anne van Els ◽  
Marianne van de Wetering ◽  
C. van Ommen
Keyword(s):  
Risk Factors ◽  
Recurrence Rate ◽  
Case Control Study ◽  
Case Control ◽  
Paediatric Oncology ◽  
Oncology Patients ◽  
Free Survival ◽  
Independent Risk Factors ◽  
Prophylactic Anticoagulation ◽  
Control Study

AbstractVenous thromboembolism (VTE) is a serious complication in paediatric oncology patients. To identify the incidence, risk factors and recurrence rate of VTE in paediatric oncology patients, an observational, retrospective cohort study of all consecutive children (≤18 years) with malignancies, treated at the Emma Children's Hospital Academic Medical Centre between January 1989 and December 2013, was done. A matched case–control study in children with lymphomas was performed, to identify thrombotic risk factors. Cumulative recurrence-free survival after first VTE was estimated by the Kaplan–Meier method. Of the 2,183 children included (male: female = 1.4:1.0; median age, 6.6 years) with cancer, 78 patients developed VTE (3.6%; 95% confidence interval [CI], 2.8–4.4). The incidence increased from 0.8% (4/478, 95% CI, 0.0–1.6) between 1989 and 1993 to 10.4% (44/423, 95% CI, 7.6–13.4) between 2009 and 2013. Independent risk factors for VTE were age ≥ 12 years, acute lymphoblastic leukaemia (ALL) and lymphoma. The case–control study in lymphoma patients showed a trend for increased VTE incidence in stage IV lymphoma. Twelve (15.4%) patients developed recurrent thrombosis, 7 patients while on therapeutic or prophylactic anticoagulation. The cumulative recurrence-free survival after first VTE was 88.5, 87.1 and 80.6% after 1, 5 and 10 years, respectively. In conclusion, we demonstrated an increasing incidence of VTE in children with malignancies, with age ≥ 12 years, ALL and lymphoma as independent risk factors. The elevated recurrence rate underlines the importance of full anticoagulant therapy and might warrant prophylactic anticoagulation after first VTE during cancer treatment.

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