scholarly journals Preliminary Definitions for Sacroiliac Joint Pathologies in the OMERACT Juvenile Idiopathic Arthritis Magnetic Resonance Imaging Score (OMERACT JAMRIS-SIJ)

2019 ◽  
Vol 46 (9) ◽  
pp. 1192-1197 ◽  
Author(s):  
Tarimobo M. Otobo ◽  
Philip G. Conaghan ◽  
Walter P. Maksymowych ◽  
Desiree van der Heijde ◽  
Pamela Weiss ◽  
...  

Objective.To develop definitions for the assessment of magnetic resonance imaging (MRI) pathologies of the sacroiliac joints (SIJ) in juvenile idiopathic arthritis.Methods.An Outcome Measures in Rheumatology (OMERACT) consensus-driven methodology consisting of iterative surveys and focus group meetings within an international group of rheumatologists and radiologists.Results.Two domains, inflammation and structural, were identified. Definitions for bone marrow edema, joint space inflammation, capsulitis, and enthesitis were derived for joint inflammation; sclerosis, erosion, fatty lesion, and ankylosis were defined for assessing structural joint changes.Conclusion.Preliminary consensus-driven definitions for inflammation and structural elements have been derived, underpinning the ongoing development of the OMERACT Juvenile Arthritis MRI SIJ scoring system (OMERACT JAMRIS-SIJ).

2012 ◽  
Vol 39 (3) ◽  
pp. 645-650 ◽  
Author(s):  
PETER BOAVIDA ◽  
RIKIN HARGUNANI ◽  
CATHERINE M. OWENS ◽  
KAREN ROSENDAHL

Objective.Magnetic resonance imaging (MRI) is playing an increasingly important role in the diagnosis and followup of juvenile idiopathic arthritis (JIA). Carpal depressions are commonly observed in healthy children and in patients with JIA. The aim of our study was to further characterize these depressions in patients with JIA.Methods.A total of 29 MRI wrist examinations were analyzed. Depressions were classified according to morphology as either tubular or focal. Features including the presence of a vessel related to the depression, evidence of synovitis, bone marrow edema, or loss of joint space on a radiograph taken on the same day were recorded for each depression.Results.A total of 173 depressions were identified in 145 carpal bones. Forty percent were capitate depressions. A third were focal depressions and two-thirds were tubular. About 10% of tubular depressions and 30% of focal depressions were associated with features suggesting true erosions, with the remainder likely to represent vascular channels and normal variants.Conclusion.Radiologists and clinicians should undertake caution when assessing carpal depressions on MRI because the vast majority are likely to represent normal variants.


2019 ◽  
Vol 57 (1) ◽  
pp. 91-99 ◽  
Author(s):  
D. M. Kudinsky ◽  
A. V. Smirnov ◽  
L. I. Alekseeva

The article discusses the possibilities and search for the optimal concept of diagnosis of hand osteoarthritis (OA). The data of numerous studies with focus on the comparison of sensitivity and specificity of the main techniques in this type of pathology – standard radiography and magnetic resonance imaging (MRI) are presented. Determination of the earliest symptoms of OA allows to predict the development of the disease and begin its therapy. The joint space narrowing due to the loss of articular cartilage is the earliest radiological symptom of OA, which is observed in the advanced stage of the disease. MRI, unlike radiography, makes it possible to visualize the articular cartilage, fluid in the joint cavity, bone marrow edema and soft tissues, but it is more expensive and time-consuming method. At present the main difficulty lies in the absence of a standardized system for assessing the MRI hand OA manifestations, as well as insufficient number of investigations in this area.


2013 ◽  
Vol 41 (2) ◽  
pp. 383-385 ◽  
Author(s):  
Philip G. Conaghan ◽  
Fiona M. McQueen ◽  
Paul Bird ◽  
Charles Peterfy ◽  
Espen Haavardsholm ◽  
...  

Magnetic resonance imaging (MRI) provides an important biomarker across a range of rheumatological diseases. At the Outcome Measures in Rheumatology (OMERACT) 11 meeting, the MRI task force continued its work of developing and improving the use of MRI outcomes for use in clinical trials. The breadth of pathology in the Rheumatoid Arthritis MRI Score has been strengthened with further work on the development of a joint space narrowing score, and a series of exercises presented at OMERACT 11 demonstrated good reliability and construct validity for this assessment. Understanding the importance of residual inflammation after RA treatment remains a major focus of the group’s work. Analyses were presented on defining the level of synovitis (using MRI scores of a single hand) that would predict absence of erosion progression. The development of the OMERACT Hand Osteoarthritis MRI score has continued with substantial work presented on its iterative development, including pathology definition, scaling, and subsequent reliability of the score. Optimizing the role of MRI as a robust biomarker and surrogate outcome remains a priority for this group.


2013 ◽  
Vol 41 (2) ◽  
pp. 354-358 ◽  
Author(s):  
Robert Hemke ◽  
Andrea S. Doria ◽  
Nikolay Tzaribachev ◽  
Mario Maas ◽  
Désirée M.F.M van der Heijde ◽  
...  

Recent advances in magnetic resonance imaging (MRI) techniques have substantially improved the evaluation of joint pathologies in juvenile idiopathic arthritis (JIA). Because of the current availability of highly effective antirheumatic therapies and the unique and useful features of MRI, there is a growing need for an accurate and reproducible MRI assessment scoring system for JIA, such as the rheumatoid arthritis MRI Scoring (RAMRIS) for patients with rheumatoid arthritis (RA). To effectively evaluate the efficacy of treatment in clinical research trials, we need to develop and validate scoring methods to accurately measure joint outcomes, standardize imaging protocols for data acquisition and interpretation, and create imaging atlases to differentiate physiologic and pathologic joint findings in childhood and adolescence. Such a standardized, validated, JIA-MRI scoring method could be used as an outcome measure in clinical trials.


Author(s):  
David J. Hunter ◽  
Frank W. Roemer ◽  
Ed Riordan

Magnetic resonance imaging (MRI) overcomes many of the limitations associated with conventional radiography, the technique historically regarded as the gold standard in imaging of osteoarthritis (OA). MRI allows visualization of changes and pathologies in joint tissues including cartilage and the menisci, the two tissue components responsible for the indirect radiographic marker of joint space narrowing, decreasing the length of time that must elapse before disease progression can be detected. Other elements of the joint can also be analysed simultaneously: a key development in the understanding of OA. This chapter focuses on the utility of MRI in observational studies and clinical trials, detailing the available MRI techniques and quantitative/qualitative measurements, and their correlation with tissue damage. The possible future directions of MRI in OA are also discussed, with a view to its potential utility in identifying disease-modifying interventions.


Author(s):  
Gonzalo André Montesinos ◽  
Rosa Cristina Peinado Agudo ◽  
André Camilo de Oliveira ◽  
André Antonio James ◽  
Jefferson Xavier Oliveira ◽  
...  

Magnetic resonance imaging is effective to diagnose some diseases that affect the temporomandibular joint (TMJ) of children. The images allow the detection of early stages of juvenile idiopathic arthritis, cases of joint ankylosis and is currently considered the most reliable exam for an objective and noninvasive assessment of intracapsular soft tissues. The objective of this literature review was to assess some of the temporomandibular joint changes in children using magnetic resonance imaging (MRI). The assessment of TMJs of children performed through MRI make the diagnosis more accurate and objective. Detecting alterations during the early stages of juvenile idiopathic arthritis using 3T MRI devices is possible utilizing contrast tools, which as a result, provides better prognosis and treatment.


2020 ◽  
Vol 8 (1) ◽  
pp. 48-53
Author(s):  
Adil Ali Khan ◽  
Rajul Rastogi ◽  
Vijai Pratap ◽  
Satish Pathak ◽  
Ajay Pant ◽  
...  

Background: Imaging modalities like ultrasonography (USG), magnetic resonance imaging (MRI) and magnetic resonance arthrography (MRAr) provide different form of information about the joint space and tendons related to the knee joint. Knee is the most frequently examined joint by MRI / MRAr as it is relatively non-invasive and highly accurate in assessing joint structures, saving majority of patients from non-therapeutic arthroscopy procedures. The main objective of this study is to understand the comparative role of routine MRI and MRAr in our hospital settings. Subjects and Methods: Twenty-five patients included in the study underwent both MRI and MRAr on the same day. Results were interpreted by radiologists and data was tabulated with the final diagnosis established on MRAr. Results: Efficacy of MRI was inferior in evaluation of Anterior Cruciate ligament, meniscal and capsular tears. In patients, where MRI was normal, MR Arthrography revealed significant findings. Conclusion: Routine MRI misses significant outcome information when compared to MRAr in evaluation of knee joint. Hence, MR Arthrography should be done for optimal evaluation of knee joints in all patients especially those with clinicoradiological discordance.


2017 ◽  
Vol 44 (8) ◽  
pp. 1224-1230 ◽  
Author(s):  
Robert Hemke ◽  
Nikolay Tzaribachev ◽  
Charlotte M. Nusman ◽  
Marion A.J. van Rossum ◽  
Mario Maas ◽  
...  

Objective.There is increasing evidence that early therapeutic intervention improves longterm joint outcome in juvenile idiopathic arthritis (JIA). Given the existence of highly effective treatments, there is an urgent need for reliable and accurate measures of disease activity and joint damage in JIA. Our objective was to assess the reliability of 2 magnetic resonance imaging (MRI) scoring methods: the Juvenile Arthritis MRI Scoring (JAMRIS) system and the International Prophylaxis Study Group (IPSG) consensus score, for evaluating disease status of the knee in patients with JIA.Methods.Four international readers independently scored an MRI dataset of 25 JIA patients with clinical knee involvement. Synovial thickening, joint effusion, bone marrow changes, cartilage lesions, bone erosions, and subchondral cysts were scored using the JAMRIS and IPSG systems. Further, synovial enhancement, infrapatellar fat pad heterogeneity, tendinopathy, and enthesopathy were scored. Interreader reliability was analyzed by using the generalized κ, ICC, and the smallest detectable difference (SDD).Results.ICC regarding interreader reliability ranged from 0.33 (95% CI 0.12–0.52, SDD = 0.29) for enthesopathy up to 0.95 (95% CI 0.92–0.97, SDD = 3.19) for synovial thickening. Good interreader reliability was found concerning joint effusion (ICC 0.93, 95% CI 0.89–0.95, SDD = 0.51), synovial enhancement (ICC 0.90, 95% CI 0.85–0.94, SDD = 9.85), and bone marrow changes (ICC 0.87, 95% CI 0.80–0.92, SDD = 10.94). Moderate to substantial reliability was found concerning cartilage lesions and bone erosions (ICC 0.55–0.72, SDD 1.41–13.65).Conclusion.The preliminary results are promising for most of the scored JAMRIS and IPSG items. However, further refinement of the scoring system is warranted for unsatisfactorily reliable items such as bone erosions, cartilage lesions, and enthesopathy.


2017 ◽  
Vol 44 (8) ◽  
pp. 1257-1264 ◽  
Author(s):  
Jill Halstead ◽  
Carmen Martín-Hervás ◽  
Elizabeth M.A. Hensor ◽  
Dennis McGonagle ◽  
Anne-Maree Keenan ◽  
...  

Objective.Foot osteoarthritis (OA) is very common but underinvestigated musculoskeletal condition and there is little consensus as to common magnetic resonance imaging (MRI) features. The aim of this study was to develop a preliminary foot OA MRI score (FOAMRIS) and evaluate its reliability.Methods.This preliminary semiquantitative score included the hindfoot, midfoot, and metatarsophalangeal joints. Joints were scored for joint space narrowing (JSN; 0–3), osteophytes (0–3), joint effusion/synovitis, and bone cysts (present/absent). Erosions and bone marrow lesions (BML) were scored (0–3) and BML were evaluated adjacent to entheses and at sub-tendon sites (present/absent). Additionally, tenosynovitis (0–3) and midfoot ligament pathology (present/absent) were scored. Reliability was evaluated in 15 people with foot pain and MRI-detected OA using 3.0T MRI multi-sequence protocols, and assessed using ICC as an overall score and per anatomical site.Results.Intrareader agreement (ICC) was generally good to excellent across the foot in joint features (JSN 0.90, osteophytes 0.90, effusion/synovitis 0.46, cysts 0.87), bone features (BML 0.83, erosion 0.66, BML entheses 0.66, BML sub-tendon 0.60) and soft tissue features (tenosynovitis 0.83, ligaments 0.77). Interreader agreement was lower for joint features (JSN 0.43, osteophytes 0.27, effusion/synovitis 0.02, cysts 0.48), bone features (BML 0.68, erosion 0.00, BML entheses 0.34, BML sub-tendon 0.13), and soft tissue features (tenosynovitis 0.35, ligaments 0.33).Conclusion.This preliminary FOAMRIS demonstrated good intrareader reliability and fair interreader reliability when assessing the total feature scores. Further development is required in cohorts with a range of pathologies and to assess the psychometric measurement properties.


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