Thyroid Dysfunction among School-Aged Children due to Chronically Excessive Iodine Groundwater, Central Java, Indonesia

2020 ◽  
Vol 13 (3) ◽  
pp. 131-138
Author(s):  
Ina Kusrini ◽  
Mohamad Samsudin ◽  
Prihatin Broto ◽  
Suryati Kumorowula ◽  
Sri Supadmi ◽  
...  
2013 ◽  
Vol 143 (12) ◽  
pp. 2038-2043 ◽  
Author(s):  
Zhongna Sang ◽  
Wen Chen ◽  
Jun Shen ◽  
Long Tan ◽  
Na Zhao ◽  
...  

Clinics ◽  
2009 ◽  
Vol 64 (2) ◽  
pp. 135-142 ◽  
Author(s):  
Glaucia C. Duarte ◽  
Eduardo K. Tomimori ◽  
Rosalinda Y. A. Camargo ◽  
Ileana G.S. Rubio ◽  
Mauricio Wajngarten ◽  
...  

2015 ◽  
Vol 31 ◽  
pp. 279-284 ◽  
Author(s):  
Inger Aakre ◽  
Trine Bjøro ◽  
Ingrid Norheim ◽  
Tor A. Strand ◽  
Ingrid Barikmo ◽  
...  

PLoS ONE ◽  
2017 ◽  
Vol 12 (11) ◽  
pp. e0187241 ◽  
Author(s):  
Inger Aakre ◽  
Tor A. Strand ◽  
Khalil Moubarek ◽  
Ingrid Barikmo ◽  
Sigrun Henjum

Author(s):  
Utami Pangestu ◽  
◽  
Yulia Lanti Retno Dewi ◽  
Hanung Prasetya ◽  
◽  
...  

ABSTRACT Background: Previous studies suggest that individual and environmental factors were associated lack of vegetable and fruit consumption, which can lead to obesity. Recent studies have indicated the level of vegetable and fruit intake in children aged 2-7 years is particularly low. The purpose of this study was to examine the effect of fruits and vegetables intake on obesity in school-aged children. Subjects and Method: This was meta-analysis and systematic review. The study was conducted by collecting published articles from Google Scholar, PubMed, Research Gate, dan Springer Link databases, from year 2011 to 2019. Keywords used ”Nutrition” OR “Obesity” AND ”Cross sectional”. The inclusion criteria were full text, using English OR Indonesian language, using cross-sectional study design, and reporting adjusted odds ratio. The study population (P) was school-aged children. Intervention (I) was fruits and vegetables intake with comparison (C) malnutrition. The study outcome (O) was obesity. The collected articles were selected by PRISMA flow chart. The quantitative data were analyzed using Revman 5.3. Results: 6 studies from Ethiopia, South Afrika, Nepal, Ghana, Saudi Arabia, reported that low fruits and vegetables intake increased the risk of obesity in school-aged children (aOR= 1.34; 95% CI= 1.06 to 1.70; p<0.001; I2= 92%). Conclusion: Low fruits and vegetables intake increased the risk of obesity in school-aged children. Keywords: obesity, nutrition, fruits and vegetables intake, school-aged children Correspondence: Utami Pangestu. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: [email protected]. Mobile: 087836021638. DOI: https://doi.org/10.26911/the7thicph.03.129


2012 ◽  
Vol 97 (8) ◽  
pp. E1363-E1369 ◽  
Author(s):  
ZhongNa Sang ◽  
Wei Wei ◽  
Na Zhao ◽  
GuiQin Zhang ◽  
Wen Chen ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Daniel Gyamfi ◽  
Yaw Amo Wiafe ◽  
Enoch Ofori Awuah ◽  
Evans Asamoah Adu ◽  
Emmanuel Kodie Boadi

Background. Iodine deficiency is a public health problem. The universal salt iodization (USI) program is the main, simple, and cost-effective intervention strategy to control iodine deficiency. The study examined the iodine status in school-aged children in Ashanti region, Ghana, using thyroid volumes along with urinary iodine concentrations, the methods recommended by the WHO/ICCIDD for monitoring the sustained impact of USI programs. Methods. This cross-sectional study was conducted among school-aged children (6–12 years) from randomly selected schools in the central and northern part of the Ashanti region, Kumasi Metropolis, and Ejura-Sekyedumase Municipality, respectively. A total of 852 children were enrolled in the study. Thyroid volume and urinary iodine concentrations of the children were determined using the standardized methods recommended by WHO/ICCIDD. Anthropometric measurements were also evaluated. Results. The mean values of thyroid volume in female and male school-aged children were 3.53 ± 0.09 and 3.32 ± 0.07, respectively. The thyroid size was significantly associated with age (P<0.0001), weight (P<0.0001), height (P<0.0001), BMI (P<0.05), and BSA (P<0.0001) by Pearson’s correlation in both males and females. The P50 (median) thyroid volumes of school children investigated in this study were generally larger compared to the WHO/ICCIDD reference data by age and body surface area. The median value of urinary iodine concentration was 201.85 μg/L, which showed significant sex difference (P value <0.0001). Excessive iodine nutrition (≥300 μg/L) was observed among 34.4% of male children and 27.6% of female children. Also, 12.8% of the male and 19.5% of the female children had UIC below requirement (<100 μg/L). The criteria of thyroid volume per age yielded a goitre prevalence of 2.2%. In contrast, the criteria of thyroid volume by body surface area yielded a goitre prevalence of 0.9%. Conclusion. The study clearly indicated that adequate iodine nutrition exists generally among the school children. However, insufficient and excessive iodine intakes still persist among some of the children. The establishment of local reference values for thyroid volume that might be applicable to precisely define goitre prevalence in the Ghanaian context is highly recommended.


2014 ◽  
Vol 18 (9) ◽  
pp. 1692-1697 ◽  
Author(s):  
Long Tan ◽  
Zhongna Sang ◽  
Jun Shen ◽  
Hua Liu ◽  
Wen Chen ◽  
...  

AbstractObjectiveTo explore (i) the prevalence of thyroid dysfunction in populations with adequate and excessive iodine intakes and (ii) the effect of iodine exposure on the prevalence of thyroid dysfunction.DesignCross-sectional study was conducted in Hebei in 2010. The population was classified as having adequate or excessive iodine intake according to the iodine concentration in drinking water. Demographic information was collected by questionnaire. Levels of serum thyroid hormones, thyroid autoantibodies and iodine in drinking water and urine were measured.SettingVillages with adequate or excessive drinking water iodine in Hebei Province, People’s Republic of China.SubjectsA total of 854 men and women aged 20–50 years who had lived in the surveyed areas for over 5 years, including 348 from the adequate iodine area (AIA) and 506 from the excessive iodine area (EIA).ResultsMedian urinary iodine concentration was 185 μg/l in AIA and 1152 μg/l in EIA. The prevalence of thyroid dysfunction in AIA was 10·3 %, which included 1·1 % with hypothyroidism and 8·1 % with subclinical hypothyroidism; and 20·6 % in EIA, which included 3·6 % with hypothyroidism and 13·6 % with subclinical hypothyroidism. The positive rates of thyroglobulin antibody were 16·1 % in AIA and 11·9 % in EIA; the positive rates of thyroperoxidase antibody were 20·7 % in AIA and 16·4 % in EIA.ConclusionsExcessive iodine intake may lead to increased prevalence of biochemical thyroid dysfunction, especially biochemical hypothyroidism. This is not related to an increase in prevalence of thyroid antibodies. Women are more susceptible to iodine excess.


2021 ◽  
Vol 16 (1) ◽  
pp. 1357-1364
Author(s):  
Yuhan Zhou ◽  
Fen Chen ◽  
Lingyu Wang ◽  
Chunhui Tian ◽  
Shuo Zhang ◽  
...  

Abstract This study aims to explore the relationship between the iodine status and thyroid dysfunction (TD) in pregnant women and establish a model to guide them to prevent excessive iodine intake. A total of 515 pregnant women were enrolled in the study. Urinary iodine concentration (UIC), thyroid hormones, and thyroid autoantibodies were measured, and then a logistic regression model was established. The median UIC of pregnant women was 174 ± 120 μg/L. Multivariate logistic regression analysis indicated that multivitamin supplements containing iodine and frequent seafood consumption were risk factors for excessive iodine (UIC ≥500 μg/L). Besides, excessive iodine was a risk factor for TD. Iodine excess was associated with a high prevalence of TD in pregnant women, especially TPOAb-positive women (P < 0.05). A logistic regression model based on potential risk factors was established to predict the risk of excessive iodine intake among pregnant women and provide guidance to minimize the risk of excessive iodine intake, thus reducing the risk of TD.


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