Longitudinal association of vitamin B-6, folate, and vitamin B-12 with depressive symptoms among older adults over time

Abstract Internet is increasingly popular among older adults and have changed interpersonal interactions. However, it remains controversial whether older people are more or less lonely with internet use. This paper tests the longitudinal association of internet use and loneliness among older people. One pathway that explains the association, the mediation effect of social contact, was examined. Data from the 2006, 2010 and 2014 waves of Health and Retirement Study was used. Hierarchical liner modeling results showed internet use was related to decreased loneliness over 12-year period of time (b=-0.044, p<.001). Internet use was associated with more social contact with family and friends overtime (b=0.261, p<.001), social contact was related to less perceived loneliness longitudinally (b=0.097, p<.001). The total effect of internet use on loneliness is -0.054 and the mediated effect is -0.025. The findings imply that online activities can be effective for reducing loneliness for older people through increased social contact.

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Longitudinal relationship of diabetes and depressive symptoms in older adults from Mexico: a secondary data analysis

BMJ Open Diabetes Research & Care ◽

10.1136/bmjdrc-2020-001789 ◽

2020 ◽

Vol 8 (2) ◽

pp. e001789

Author(s):

Teresa Alvarez-Cisneros ◽

Paloma Roa-Rojas ◽

Carmen Garcia-Peña

Keyword(s):

Risk Factors ◽

Older Adults ◽

Depressive Symptoms ◽

Secondary Data ◽

Random Effects Models ◽

Health Factors ◽

Longitudinal Association ◽

Common Risk Factors ◽

Nationally Representative ◽

Relationship Of

IntroductionSeveral studies have argued a causal relationship between diabetes and depression, while others have highlighted that their association is a result of common risk factors. Because Mexico is a country with a high prevalence of diabetes, and diabetes and depression are a frequent comorbidity, we chose this country to investigate the longitudinal relationship of these two conditions, focusing on the influence of demographic, health, and socioeconomic factors which could act as common risk factors for both conditions.Research design and methodsUsing the harmonized Mexican Health and Aging Study, a nationally representative sample of adults older than 50 with a response rate of 93%, we analyzed the longitudinal relationship of diabetes and depressive symptoms using ‘between-within’ random-effects models, focusing on the effect of demographic, socioeconomic and health factors.ResultsWhile older adults with diabetes reported a higher prevalence of depressive symptoms in the four waves of the study, there was no causal longitudinal association between them once controlling for demographic, socioeconomic and health factors (between-effect OR=0.88, 95% CI 0.77 to 1.01; within-effect OR=0.87, 95% CI 0.69 to 1.11).ConclusionsThere is no causal longitudinal association between diabetes and depression; the higher prevalence of depression among older adults with diabetes seems a result of socioeconomic and health factors that are not exclusive to respondents with diabetes but are more frequent in this group. Our results highlight the importance of prevention and control of chronic conditions as well as the role of socioeconomic inequalities in mental health.

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Longitudinal Association Between Depressive Symptoms and Incident Type 2 Diabetes Mellitus in Older Adults

Archives of Internal Medicine ◽

10.1001/archinte.167.8.802 ◽

2007 ◽

Vol 167 (8) ◽

pp. 802 ◽

Cited By ~ 106

Author(s):

Mercedes R. Carnethon

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Older Adults ◽

Type 2 Diabetes Mellitus ◽

Depressive Symptoms ◽

Incident Type ◽

Incident Type 2 Diabetes ◽

Longitudinal Association

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Low Vitamin B-12 Intake and Status Are More Prevalent in Hispanic Older Adults of Caribbean Origin Than in Neighborhood-Matched Non-Hispanic Whites

Journal of Nutrition ◽

10.1093/jn/132.7.2059 ◽

2002 ◽

Vol 132 (7) ◽

pp. 2059-2064 ◽

Cited By ~ 39

Author(s):

Laurinda L. Kwan ◽

Odilia I. Bermudez ◽

Katherine L. Tucker

Keyword(s):

Older Adults ◽

Vitamin B ◽

Vitamin B 12

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Longitudinal Relationships Between Subjective Cognitive Decline and Objective Memory: Depressive Symptoms Mediate Between-Person Associations

Journal of Alzheimer s Disease ◽

10.3233/jad-210230 ◽

2021 ◽

pp. 1-14

Author(s):

Nikki L. Hill ◽

Sakshi Bhargava ◽

Emily Bratlee-Whitaker ◽

Jennifer R. Turner ◽

Monique J. Brown ◽

...

Keyword(s):

Older Adults ◽

Depressive Symptoms ◽

Cognitive Decline ◽

Structural Equation ◽

Disease Risk ◽

Well Being ◽

Equation Modeling ◽

Subjective Cognitive Decline ◽

Future Research ◽

Over Time

Background: Subjective cognitive decline (SCD) may be an early indicator of cognitive impairment, but depressive symptoms can confound this relationship. Associations may be influenced by differences between individuals (i.e., between-persons) or how each individual changes in their experiences over time (i.e., within-persons). Objective: We examined depressive symptoms as a mediator of the between- and within-person associations of SCD and objective memory in older adults. Methods: Coordinated analyses were conducted across four datasets drawn from large longitudinal studies. Samples (range: n = 1,889 to n = 15,841) included participants 65 years of age or older with no dementia at baseline. We used multilevel structural equation modeling to examine the mediation of SCD and objective memory through depressive symptoms, as well as direct relationships among SCD, objective memory, and depressive symptoms. Results: Older adults who were more likely to report SCD had lower objective memory on average (between-person associations), and depressive symptoms partially mediated this relationship in three of four datasets. However, changes in depressive symptoms did not mediate the relationship between reports of SCD and declines in objective memory in three of four datasets (within-person associations). Conclusion: Individual differences in depressive symptoms, and not changes in an individual’s depressive symptoms over time, partially explain the link between SCD and objective memory. Older adults with SCD and depressive symptoms may be at greater risk for poor cognitive outcomes. Future research should explore how perceived changes in memory affect other aspects of psychological well-being, and how these relationships influence cognitive decline and Alzheimer’s disease risk.

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