scholarly journals Avascular Necrosis of Femoral Head in HIV-infected Patients: Case Reports and Review of the Literature

2012 ◽  
Vol 44 (6) ◽  
pp. 508 ◽  
Author(s):  
Jinyong Park ◽  
Kangil Jun ◽  
Min Jae Kim ◽  
Younghee Jung ◽  
Myung Jin Lee ◽  
...  
Keyword(s):  
Femoral Head ◽  
Avascular Necrosis ◽  
Case Reports ◽  
Review Of The Literature ◽  
Necrosis Of Femoral Head

Steroid induced avascular necrosis of femoral head in ALL patients-two case reports

JMS SKIMS ◽  
2020 ◽  
Vol 23 (2) ◽  
Author(s):  
Faisal Guru ◽  
Syed Nisar ◽  
Saquib Zaffar Banday ◽  
Gul Mohammad Bhat ◽  
Saqib Ahmad Shah ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Young Adults ◽  
Side Effects ◽  
Femoral Head ◽  
Children And Adolescents ◽  
Avascular Necrosis ◽  
Case Reports ◽  
Mineral Density ◽  
Necrosis Of Femoral Head ◽  
Avascular Necrosis Of Bone

Avascular necrosis of bone or Osteonecrosis incidence has been increasing in a larger number of surviving ALL patients, especially in adolescents and young adults [1]. Osteonecrosis and decreased bone mineral density(BMD) are well-known side effects of corticosteroids and avascular necrosis has been reported as one of the leading causes of treatment related morbidity in ALL survivors [2]. Symptomatic avascular necrosis has been reported to occur in up to 20% of children and adolescents with ALL [3]. We are reporting two cases of ALL patients who have been treated with steroid and chemotherapy and developed avascular necrosis of bilateral femoral heads.

Avascular Necrosis of Femoral Head: Findings of Contrast-Enhanced MR Imaging

1995 ◽  
Vol 32 (6) ◽  
pp. 953
Author(s):  
Young Min Kim ◽  
Hee Joong Kim ◽  
Heung Sik Kang ◽  
Chu Wan Kim ◽  
Yong Moon Shin
Keyword(s):  
Femoral Head ◽  
Mr Imaging ◽  
Avascular Necrosis ◽  
Contrast Enhanced ◽  
Necrosis Of Femoral Head

scholarly journals Corticosteroid induced avascular necrosis and COVID-19: The drug dilemma

2021 ◽  
Vol 11 (3) ◽  
pp. 1049-1052
Author(s):  
Indrajit Banerjee ◽  
Jared Robinson ◽  
Brijesh Sathian
Keyword(s):  
Adverse Effect ◽  
Femoral Head ◽  
Avascular Necrosis ◽  
Steroid Therapy ◽  
Case Reports ◽  
Weight Bearing ◽  
Inflammatory Cells ◽  
High Dose ◽  
Intraosseous Pressure ◽  
Femoral Head Osteonecrosis

The severe and life-threatening nature of the COVID-19 infection, the ARDS (acute respiratory distress syndrome) as well as the cytokine storm induced by the infection, commands lifesaving high doses of steroid therapy. As in all pharmacological therapies adverse effects are present. One such adverse effect which is being reported is corticosteroid induced avascular necrosis of the femoral head/ osteonecrosis of the femoral head. It must be noted that AVN principally affects the femoral head and most commonly the anterolateral aspect thereof as it is the crux of weight bearing.  Corticosteroids induce fat mobilization and this thus innately enhances the likelihood of fat emboli developing from the liver to occlude minor blood vessels in the femur, this thereby compromises the microvascular environment. Superadded to this the steroid therapy disrupts calcium metabolism and homeostasis which induces hypertrophy in the intramedullary fat cells, Gaucher cells and inflammatory cells; whilst increasing the activity of osteoclasts, thus increasing bone resorption and decreasing calcium uptake and deposition; ultimately leading to an insufficiency in the trabecular and cortical bone. This insufficiency thus equates to an increased intraosseous pressure which impedes intramedullary circulation and results in avascular necrosis.  It is evident that avascular necrosis is directly caused by high dose steroid therapy, however the case reports have very clearly indicated that the rapid onset of AVN post recovery from the COVID-19 infection cannot be solely attributed to steroid therapy and that another benefactor induced by the COVID-19 infection is at play. It is thus vital for treating physicians to take cognisance of this adverse effect post recovery and therefore should ensure that prophylactic bisphosphonate therapy is initiated timeously and congruently.

scholarly journals The results of core decompression treatment in patients with avascular necrosis of femoral head in patients at Isfahan City educational hospitals in 2010-2011

2014 ◽  
Vol 3 (1) ◽  
pp. 93 ◽  
Author(s):  
Mehdi Kooskzari ◽  
MehrabiKooshki Ali ◽  
Khalilollah Nazem ◽  
Behnamoon Mahsa ◽  
Mohammadreza Etemadifar
Keyword(s):  
Femoral Head ◽  
Avascular Necrosis ◽  
Core Decompression ◽  
Necrosis Of Femoral Head

scholarly journals Postoperative Collapse of Femoral Head in Patients with Rotational Osteotomy for Non-traumatic Avascular Necrosis of Femoral Head.

1999 ◽  
Vol 48 (1) ◽  
pp. 196-198
Author(s):  
Atsuhiko Wakisaka ◽  
Hiroshi Tanaka ◽  
Kenji Kide ◽  
Toru Moriwaki ◽  
Michio Shinohara ◽  
...  
Keyword(s):  
Femoral Head ◽  
Avascular Necrosis ◽  
Rotational Osteotomy ◽  
Necrosis Of Femoral Head

ROLE OF DASHMOOLADI MAJJA SNEHA (THERAPEUTIC ENEMA) IN AVASCULAR NECROSIS: A CASE STUDY

2021 ◽  
pp. 56-57
Author(s):  
Jakra Priyanka ◽  
Mishra Meenu ◽  
Soni Kamini
Keyword(s):  
Femoral Head ◽  
Avascular Necrosis ◽  
Classical Method ◽  
Symptomatic Relief ◽  
Modern Medicine ◽  
Neck Of Femur ◽  
Glucocorticoid Treatment ◽  
And Function ◽  
Necrosis Of Femoral Head

Introduction:Avascular necrosis is also known as aseptic, osteonecrosis and ischaemic necrosis of bone. There are a multitude of risk factors but over 80% of cases are attributed to glucocorticoid treatment or alcohol excess. Avascular Necrosis of femoral head is the most common type of necrosis, because the artery supplying to neck of femur is very narrow which easily gets injured. In modern medicine there is no specic treatment rather than surgery. In Ayurveda avascular necrosis can be correlated with Asthimajjagatvata. Aim: To assess the efcacy of Dashmooladi Majja Sneha in the management of avascular necrosis. The objective of the treatment includes the preservation of structure and function of hip joint with symptomatic relief. Materials & Methods:The present case study is upon a 32 year old, diagnosed case of avascular necrosis of femoral head with complaints of pain in bilateral sacroiliac joint since one and half years which was associated with difculty in doing normal daily activities such as walking, sitting, squatting along with change in the gait, at the Panchakarma OPD of Govt. Ayurvedic hospital Bhopal. The patient of idiopathic AVN of femoral head was treated with Dashmooladi Majja Sneha, Brihatvata Chintamani Rasa, Amritaristha, Panchtikta Ghrita Guggulu and Shastik Shali Pind Swedan have done as per the classical method for 30 days. Assessment was done after treatment and follow up after 15 days for 2months. Observations: The Ayurvedic therapies and oral medicines yielded complete symptomatic relief from pain, general debility and improvement in the gait. Conclusion: On the basis of the results obtained it can be concluded that Dashmooladi Majja Sneha, Shastik Shali Pind Swedan and some oral medicines can be used as an effective treatment in the management of Avascular Necrosis.

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