Objectives: NT-ProBNP could influence the pacemaker parameters in patients with sick sisnus syndrome?
Methods and Results: 93 patients with sick sinus syndrome were implanted 2 chambers pacemaker with mean aged 61,19±14,95 years old and 37,6% of male. The pacemaker parameters of ventricular lead include: Pacing thresholds were measured 0.75 ± 0.17 V, sensing amplitudes were measured 9,93 ± 4.01 mV, and lead impedances were measured 710,06 ± 130,86 ᾨ. The pacemaker parameters of atrial lead include: Pacing thresholds were measured 1,06 ± 0,29 V, sensing amplitudes were measured 2,58 ± 1,23 mV, and lead impedances were measured 509,13 ± 69,22 ᾨ. There is not significantly relationships of NT-ProBNP and pacemaker parameters of ventricular lead, atrial lead impedance, atrial lead sensing amplitudes (p>0,05). However, there is significantly relationship of NT-ProBNP and atrial lead pacing threshold (r=0,34; p=0,003).
Conclusion: There is significantly relationship of NT proBNP and atrial lead pacing threshold in patients with sick sinus syndrome who were implanted the pacemaker.