scholarly journals Serum levels of the complements and circulating immune complexes in chronic hemodialysis patients with diabetes mellitus.

1991 ◽  
Vol 24 (10) ◽  
pp. 1333-1339
Author(s):  
Yasufumi Arirmto ◽  
Kazuhiko Tsuboi ◽  
Akira Nishio ◽  
Masaru Iida
Keyword(s):  
Diabetes Mellitus ◽  
Immune Complexes ◽  
Serum Levels ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Circulating Immune Complexes ◽  
Patients With Diabetes

scholarly journals Nursing problems and exercise conditioning using a pedometer in chronic hemodialysis patients with diabetes mellitus.

1990 ◽  
Vol 23 (9) ◽  
pp. 997-1001
Author(s):  
Atsuko Kato ◽  
Sueko Hisamatsu ◽  
Emiko Izumi ◽  
Tsuyumi Ochi ◽  
Miki Ikeda ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Patients With Diabetes

Glycemic Control and Infections among U.S. Hemodialysis Patients with Diabetes Mellitus

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1588-P
Author(s):  
JINNIE J. RHEE ◽  
YUANCHAO ZHENG ◽  
MARIA MONTEZ-RATH ◽  
WOLFGANG WINKELMAYER
Keyword(s):  
Diabetes Mellitus ◽  
Glycemic Control ◽  
Hemodialysis Patients ◽  
Patients With Diabetes

scholarly journals Evaluation of Serum Immunoglobulins (IgG, IgA, IgM) and Circulating Immune Complexes in Oral Precancer and Cancer Patients

2021 ◽  
Author(s):  
Pooja Madki ◽  
Mandya Lakshman Avinash Tejasvi ◽  
Geetha Paramkusam ◽  
Ruheena Khan ◽  
Shilpa J.
Keyword(s):  
Oral Cancer ◽  
Immune Complexes ◽  
Serum Levels ◽  
Circulating Immune Complexes ◽  
Oral Cancers ◽  
Cancer Group ◽  
Oral Precancer ◽  
Serum Iga ◽  
The Mean

Abstract Objectives The aim of the present study is to evaluate the role of immunoglobulins (IgA, IgG, and IgM) and circulating immune complexes (CIC) as tumor marker in oral cancer and precancer patients. Materials and Methods The present study was performed on 45 individuals subdivided into three groups, that is, oral precancer, oral cancer and healthy individuals, and levels of immunoglobulins, and CIC was estimated by turbidometry and ELISA method. Results In the present study, the mean serum IgA levels in oral precancer were 161.00 ( ±  118.02) mg/dL, oral cancers were 270.67 ( ±  171.44) mg/dL, and controls were 133.73 ( ±  101.31) mg/dL. Mean serum levels of IgG in oral precancer were 1,430.87 ( ±  316) mg/dL, oral cancers were 1,234.27 ( ±  365.42) mg/dL, and controls were 593.87 ( ±  323.06) mg/dL. Conclusion We found that the levels of serum IgG and IgA were elevated consistently in precancer and cancer group, and Serum IgM levels were increased only in precancer. Also, significant increase in serum CIC levels were seen in oral precancer and cancer group on comparison with control.

scholarly journals Non-Insulin-Dependent Diabetes Mellitus and Hypertriglyceridemia Impair Lipoprotein Metabolism in Chronic Hemodialysis Patients

1999 ◽  
Vol 10 (2) ◽  
pp. 332-341
Author(s):  
THOMAS QUASCHNING ◽  
MICHAEL SCHÖMIG ◽  
MARKUS KELLER ◽  
JOACHIM THIERY ◽  
MATTHIAS NAUCK ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Scavenger Receptor ◽  
Ldl Receptor ◽  
Lipoprotein Metabolism ◽  
Peritoneal Macrophages ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Ldl Oxidation ◽  
Diabetic Patients ◽  
Cumulative Impact

Abstract. Patients with diabetes mellitus undergoing chronic hemodialysis treatment have the worst outcome on dialysis due to an increased rate of cardiovascular complications. Nearly all patients present with dyslipidemia, a prominent vascular risk factor, probably responsible for the high rate of vascular injury. Since both uremia and diabetes predispose to hypertriglyceridemia, the present study was conducted to investigate the influence of diabetes mellitus and/or hypertriglyceridemia on lipoprotein metabolism in hemodialysis patients. LDL was isolated and characterized from hyper- and normotriglyceridemic diabetic and nondiabetic hemodialysis patients (n = 40; 10 in each group); also, LDL-receptor-dependent uptake and intracellular cholesterol metabolism were studied in HepG2 cells. In addition, scavenger-receptor-mediated uptake was examined in mouse peritoneal macrophages. LDL isolated from nondiabetic normotriglyceridemic hemodialysis patients exhibited impaired cellular uptake via the LDL receptor. Additionally, intracellular sterol synthesis was less inhibited and cholesterol esterification was reduced compared with LDL from healthy control subjects. Reduction of catabolic capacities was more marked in hemodialysis patients who were either diabetic or hypertriglyceridemic and even more pronounced in patients presenting with a combination of both diabetes and hypertriglyceridemia. Hypertriglyceridemic and diabetic patients showed reduced lipase activity and increased LDL oxidation. Furthermore, they accumulated a fraction of small, dense LDL, and LDL was predominantly taken up via the scavenger-receptor pathway in peritoneal macrophages. This study elucidates the distinct influence of diabetes and/or hypertriglyceridemia in hemodialysis patients on cellular LDL metabolism via specific and nonspecific metabolic pathways. Furthermore, it underscores the cumulative impact of these pathologic entities on impairment of lipoprotein metabolism and increase of cardiovascular risk.

Higher Serum Bisphenol A Levels in Diabetic Hemodialysis Patients

2016 ◽  
Vol 42 (1) ◽  
pp. 77-82 ◽  
Author(s):  
Faruk Turgut ◽  
Sana Sungur ◽  
Ramazan Okur ◽  
Mustafa Yaprak ◽  
Muge Ozsan ◽  
...  
Keyword(s):  
Bisphenol A ◽  
High Performance ◽  
Patient Characteristics ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Dialysis Session ◽  
Laboratory Parameters ◽  
Hemodialysis Session ◽  
Before And After ◽  
Patients With Diabetes

Background: Bisphenol A (BPA) has been implicated as an ‘endocrine disruptor'. We aimed at exploring the association between serum BPA levels and patient characteristics, particularly the presence of diabetes mellitus, and laboratory parameters in hemodialysis patients. Methods: This study included 47 chronic hemodialysis patients. Patient characteristics were recorded. Blood was drawn before and after hemodialysis session. Serum BPA levels were measured by the high-performance-liquid-chromatography and laboratory parameters were measured by using standard methods. Results: In hemodialysis patients, postdialysis serum BPA levels were significantly higher than predialysis after a single hemodialysis session (5.57 ± 1.2 vs. 4.06 ± 0.73, p < 0.0001). Predialysis serum BPA levels were significantly higher in patients with diabetes than non-diabetics (4.4 ± 0.6 vs. 3.9 ± 0.7, p = 0.025). No association was found between serum BPA levels and patient characteristics, and particularly laboratory parameters. Conclusion: Serum BPA levels were rising significantly after a single dialysis session. Diabetic hemodialysis patients had higher predialysis serum BPA levels.

scholarly journals SP569PROGNOSTIC IMPORTANCE OF GLYCATED MARKERS ON CARDIOVASCULAR MORTALITY IN HEMODIALYSIS PATIENTS WITH DIABETES MELLITUS -5 YEARS FOLLOW UP

2018 ◽  
Vol 33 (suppl_1) ◽  
pp. i540-i540
Author(s):  
Ana Bulatovic ◽  
Petar Djuric ◽  
Jelena Tosic ◽  
Aleksandar Jankovic ◽  
Jovan Popovic ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Cardiovascular Mortality ◽  
Hemodialysis Patients ◽  
Patients With Diabetes

scholarly journals Glycemic Control and Infections Among US Hemodialysis Patients With Diabetes Mellitus

2020 ◽  
Vol 5 (7) ◽  
pp. 1014-1025 ◽  
Author(s):  
Jinnie J. Rhee ◽  
Yuanchao Zheng ◽  
Sai Liu ◽  
Maria E. Montez-Rath ◽  
Richard J. Hamill ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Glycemic Control ◽  
Hemodialysis Patients ◽  
Patients With Diabetes

The in vivo effect of thymic factor (thymostimulin) administration on circulating immune complexes and serum lysozyme levels in untreated Hodgkin's disease patients.

1983 ◽  
Vol 1 (2) ◽  
pp. 117-125 ◽  
Author(s):  
A Velardi ◽  
F Spinozzi ◽  
P Rambotti ◽  
A Tabilio ◽  
A Losito ◽  
...  
Keyword(s):  
Immune Complexes ◽  
Hodgkin's Disease ◽  
Hodgkin’S Disease ◽  
Serum Levels ◽  
Mean Value ◽  
Circulating Immune Complexes ◽  
Calf Thymus ◽  
Serum Lysozyme ◽  
Thymic Factor

The in vivo effect of a calf thymus extract, thymostimulin, on the levels of circulating immune complexes (CIC) and serum lysozyme was evaluated in 32 patients with untreated Hodgkin's disease. Using the platelet aggregation test for detecting CICs, 12 patients (37%) had positive titers before thymostimulin treatment; 3 patients (10%) remained positive following therapy. Serum levels of Clq-binding immune complexes were evaluated (greater than 24.5 micrograms/ml) in 8 patients prior to thymostimulin therapy (mean value: 42.3 micrograms/ml); 3 patients continued to have elevated levels after treatment. Serum lysozyme levels for Hodgkin's patients was similar to control values (10.6 vs. 8.3 micrograms/ml); however, the Hodgkin's patients with initially elevated CICs had a lower serum lysozyme level than patients with initially normal CICs (12.9 vs. 7.3, p less than 0.02). Thymostimulin increased serum lysozyme levels in the Hodgkin's patients in whom the CICs were initially elevated (7.3 vs. 10.4 micrograms/ml, p less than 0.05). These data suggest that thymostimulin exerts an effect on the nonspecific immune system of Hodgkin's disease patients.

scholarly journals A szénhidrát-anyagcsere és a gyulladásos folyamatok jellemzésére szolgáló új marker, a szérumprogranulin diagnosztikai és prognosztikai szerepéről

2019 ◽  
Vol 160 (25) ◽  
pp. 973-979
Author(s):  
Bíborka Nádró ◽  
Ferenc Sztanek ◽  
Hajnalka Lőrincz ◽  
Dénes Páll ◽  
György Paragh ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Serum Levels ◽  
Obesity And Diabetes ◽  
Patients With Diabetes ◽  
Factor Α ◽  
Necrosis Factor ◽  
Reduced Renal Function

Abstract: Progranulin is a recently recognized multifunctional glycopeptide shown to be related to obesity and diabetes mellitus. Progranulin is an endogenous antagonist of tumor necrosis factor-α by competitively binding to its receptor, therefore, it exerts anti-inflammatory activity. Paradoxically, previous studies have shown that serum levels of progranulin were elevated in patients with diabetes and associated to its complications including micro- and macroangiopathies, macroalbuminuria or reduced renal function. Moreover, hyperprogranulinemia may be involved in the pathogenesis of obesity-associated insulin resistance. The review summarizes the currently available data on progranulin as a novel marker of the carbohydrate metabolism and inflammation. Orv Hetil. 2019; 160(25): 973–979.

Erectile dysfunction in hemodialysis patients with diabetes mellitus: Association with age and hemoglobin A1c levels

2004 ◽  
Vol 11 (7) ◽  
pp. 530-534 ◽  
Author(s):  
YASUYOSHI MIYATA ◽  
KAZUHIKO SHINDO ◽  
FUKUZO MATSUYA ◽  
MITSURU NOGUCHI ◽  
MASAHARU NISHIKIDO ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Erectile Dysfunction ◽  
Hemoglobin A1c ◽  
Hemodialysis Patients ◽  
Patients With Diabetes
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