Biomedical Information Processing and Visualization for Minimally Invasive Neurosurgery

Author(s):  
Hongen Liao

This chapter demonstrates a particular application of biomedical information processing and visualization techniques for minimally invasive diagnosis and therapy in neurosurgery. Computer-assisted surgical navigation provides surgeons valuable information on the precision location of surgical targets and critical areas, as well as the positions of surgical instruments. However, most navigation systems use pre-/intra-operative images, which are displayed on a two-dimensional (2D) display situated away from the surgical field. These setups force the surgeon to take extra steps to match navigation information on the display with the actual surgical target of the patient. Two typical medical information-based navigation systems for neurosurgery are described in this chapter. First, an integration system with fluorescence-based intra-operative diagnosis and laser ablation-based, high-precision, minimally invasive treatment is introduced. Second, an autostereoscopic image-guided surgical system developed for minimally invasive neurosurgery is discussed. The autostereoscopic image and corresponding augmented reality with three-dimensional (3D) image overlay have been used in open magnetic resonance imaging (MRI)-guided neurosurgery. These techniques enable intra-operative visualization of surgical targets for precision tumor resection.

Sensors ◽  
2021 ◽  
Vol 21 (23) ◽  
pp. 7824
Author(s):  
Mónica García-Sevilla ◽  
Rafael Moreta-Martinez ◽  
David García-Mato ◽  
Alicia Pose-Diez-de-la-Lastra ◽  
Rubén Pérez-Mañanes ◽  
...  

Patient-specific instruments (PSIs) have become a valuable tool for osteotomy guidance in complex surgical scenarios such as pelvic tumor resection. They provide similar accuracy to surgical navigation systems but are generally more convenient and faster. However, their correct placement can become challenging in some anatomical regions, and it cannot be verified objectively during the intervention. Incorrect installations can result in high deviations from the planned osteotomy, increasing the risk of positive resection margins. In this work, we propose to use augmented reality (AR) to guide and verify PSIs placement. We designed an experiment to assess the accuracy provided by the system using a smartphone and the HoloLens 2 and compared the results with the conventional freehand method. The results showed significant differences, where AR guidance prevented high osteotomy deviations, reducing maximal deviation of 54.03 mm for freehand placements to less than 5 mm with AR guidance. The experiment was performed in two versions of a plastic three-dimensional (3D) printed phantom, one including a silicone layer to simulate tissue, providing more realism. We also studied how differences in shape and location of PSIs affect their accuracy, concluding that those with smaller sizes and a homogeneous target surface are more prone to errors. Our study presents promising results that prove AR’s potential to overcome the present limitations of PSIs conveniently and effectively.


Author(s):  
Yu Qu ◽  
Hui Zhuang ◽  
Meng Zhang ◽  
Yufeng Wang ◽  
Dong Zhai ◽  
...  

Although calcium phosphate cements (CPC) have been clinically used to repair bone defects caused by bone tumor resection, traditional CPC cannot kill the remaining tumor cells after surgery and prevent...


Sarcoma ◽  
2010 ◽  
Vol 2010 ◽  
pp. 1-8 ◽  
Author(s):  
Pierre-Louis Docquier ◽  
Laurent Paul ◽  
Olivier Cartiaux ◽  
Christian Delloye ◽  
Xavier Banse

Pelvic sarcoma is associated with a relatively poor prognosis, due to the difficulty in obtaining an adequate surgical margin given the complex pelvic anatomy. Magnetic resonance imaging and computerized tomography allow valuable surgical resection planning, but intraoperative localization remains hazardous. Surgical navigation systems could be of great benefit in surgical oncology, especially in difficult tumor location; however, no commercial surgical oncology software is currently available. A customized navigation software was developed and used to perform a synovial sarcoma resection and allograft reconstruction. The software permitted preoperative planning with defined target planes and intraoperative navigation with a free-hand saw blade. The allograft was cut according to the same planes. Histological examination revealed tumor-free resection margins. Allograft fitting to the pelvis of the patient was excellent and allowed stable osteosynthesis. We believe this to be the first case of combined computer-assisted tumor resection and reconstruction with an allograft.


2020 ◽  
Vol 9 (7) ◽  
pp. 2120
Author(s):  
Luc Van Doorne ◽  
Pedram Gholami ◽  
Jan D’haese ◽  
Geert Hommez ◽  
Gert Meijer ◽  
...  

Background: Free-handed, flaplessly placed mini dental implants (MDIs) are a valuable, more affordable and minimally invasive treatment to support overdentures in fully edentulous jaws, especially for medically compromised patients. However, critical 3D radiographic evaluation is lacking. This multicenter prospective case series assessed clinical outcome and carried out 3D- cone-beam computerized tomography (CBCT) analysis of free-handed flaplessly placed one-piece maxillary MDIs by an experienced maxillofacial surgeon. Methods: Thirty-one patients suffering from an ill-fitting maxillary denture relating to compromised bone volume (as confirmed on CBCT), with a dentate mandible, were selected. They received 5–6 MDIs free-hand flaplessly placed and mentally guided with preoperative CBCT. Final connection and attachment activation took place six months later. After two years each implant was individually assessed with CBCT for perforations on eight sites. Implant survival, prosthetic failure, clinical stability and sinus/nasal complaints were registered after three years. Results: 32/185 (17.3%) MDIs failed during the provisional loading with non-activated attachments; 17 replacements in 10 patients were performed. Of the 170 actively loaded 170 MDIs, 82.3% survived and 27/31 prostheses (87%) were fully functional. In total 98/170 MDIs showed no perforation. Based on 1360 CBCT observations, 231 perforations (16.9%) were registered. Of most perforations 37 (25%) were observed at the apical tip and 37 were positioned (21%) into the sinus/nasal cavity, although without clinical complaints. Conclusions: Given the compromised population, the minimally invasive procedure and the low treatment cost involved, a failure rate of 17% is substantial, however clinically acceptable given the critical bone condition. However, even in experienced surgical hands, freehanded and flapless placement yield a high risk for implant perforation, although this did not necessarily lead to complications.


2006 ◽  
Vol 105 (3) ◽  
pp. 406-411 ◽  
Author(s):  
Andreas Raabe ◽  
Jürgen Beck ◽  
Stefan Rohde ◽  
Joachim Berkefeld ◽  
Volker Seifert

Object The aim of this study was to investigate the feasibility of integrating three-dimensional rotational angiography (3D-RA) data into a surgical navigation system and to assess its accuracy and potential clinical benefit. Methods The study cohort consisted of 16 patients with 16 intracranial aneurysms who had been scheduled for routine or emergency surgery. Rotational angiography data were exported using a virtual reality modeling language file format and imported into the BrainLAB VectorVision2 image-guided surgery equipment. During 3D-RA the position of the head was measured using a special headframe. The authors also determined the accuracy of 3D-RA image guidance and the clinical benefit as judged by the surgeon, including, for example, early identification of branching vessels and the aneurysm. There was good correspondence between the 3D-RA–based navigation data and the intraoperative vascular anatomy in all cases, with a maximum error of 9° of angulation and 9° of rotation. In eight cases, the surgeon determined that the 3D-RA image guidance facilitated the surgical procedure by predicting the location of the aneurysm or the origin of a branching artery that had been covered by brain tissue and blood clots. Conclusions The integration of 3D-RA into surgical navigation systems is feasible, but it currently requires a new perspective-registration technique. The intraoperative 3D view provides useful information about the vascular anatomy and may improve the quality of aneurysm surgery in selected cases.


2012 ◽  
Vol 249-250 ◽  
pp. 1277-1282
Author(s):  
Bo Yang ◽  
Ya Zhou ◽  
Xiao Ming Hu ◽  
Jun Qin Lin ◽  
Qiao Na Xing

Endoscopic surgery is increasing for minimally invasive treatment in recent years.But the conventional two-dimensional endoscope technique cannot provide three-dimensional information for surgeon. Lacking depth and other 3D information often made doctorshave to carry out the surgery depending heavily clinical experience.In response to the above described issues,this paper proposed a method based on improved SIFT algorithmto recover 3D structure information of the endoscopic environment, with the help of an optical tracking system which can provide the orientation of the camera in real time. The proposed approach is evaluated on sequence digital images gotten from an 1394 camera and the experimental results show that the proposed approach iseffective.


Sensors ◽  
2021 ◽  
Vol 21 (4) ◽  
pp. 1370
Author(s):  
Rafael Moreta-Martinez ◽  
Alicia Pose-Díez-de-la-Lastra ◽  
José Antonio Calvo-Haro ◽  
Lydia Mediavilla-Santos ◽  
Rubén Pérez-Mañanes ◽  
...  

During the last decade, orthopedic oncology has experienced the benefits of computerized medical imaging to reduce human dependency, improving accuracy and clinical outcomes. However, traditional surgical navigation systems do not always adapt properly to this kind of interventions. Augmented reality (AR) and three-dimensional (3D) printing are technologies lately introduced in the surgical environment with promising results. Here we present an innovative solution combining 3D printing and AR in orthopedic oncological surgery. A new surgical workflow is proposed, including 3D printed models and a novel AR-based smartphone application (app). This app can display the patient’s anatomy and the tumor’s location. A 3D-printed reference marker, designed to fit in a unique position of the affected bone tissue, enables automatic registration. The system has been evaluated in terms of visualization accuracy and usability during the whole surgical workflow. Experiments on six realistic phantoms provided a visualization error below 3 mm. The AR system was tested in two clinical cases during surgical planning, patient communication, and surgical intervention. These results and the positive feedback obtained from surgeons and patients suggest that the combination of AR and 3D printing can improve efficacy, accuracy, and patients’ experience.


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