Bring Out Your Data

2012 ◽  
pp. 126-145
Author(s):  
Thomas E. Grissom ◽  
Andrew DuKatz ◽  
Hubert A. Kordylewski ◽  
Richard P. Dutton
Keyword(s):  
Cost Effective ◽  
Regulatory Oversight ◽  
Measurement Quality ◽  
Related Data ◽  
Healthcare Data ◽  
Effective Manner ◽  
Wide Range ◽  
Automated Process ◽  
User Friendly ◽  
Quality Institute

Recent healthcare legislation, financial pressures, and regulatory oversight have increased the need to create improved mechanisms for performance measurement, quality management tracking, and outcomes-based research. The Anesthesia Quality Institute (AQI) has established the National Anesthesia Clinical Outcomes Registry (NACOR) to support these requirements for a wide-range of customers including individual anesthesiologists, anesthesia practices, hospitals, and credentialing agencies. Concurrently, the availability of increased digital sources of healthcare data make it possible to capture massive quantities of data in a more efficient and cost-effective manner than ever before. With NACOR, AQI has established a user-friendly, automated process to effectively and efficiently collect a wide-range of anesthesia-related data directly from anesthesia practices. This review will examine the issues guiding the evolution of NACOR as well as some potential pitfalls in its growth and usage.

Bring Out Your Data

2011 ◽  
Vol 2 (2) ◽  
pp. 51-69 ◽  
Author(s):  
Thomas E. Grissom ◽  
Andrew DuKatz ◽  
Hubert A. Kordylewski ◽  
Richard P. Dutton
Keyword(s):  
Cost Effective ◽  
Regulatory Oversight ◽  
Measurement Quality ◽  
Related Data ◽  
Healthcare Data ◽  
Effective Manner ◽  
Wide Range ◽  
Automated Process ◽  
User Friendly ◽  
Quality Institute

Recent healthcare legislation, financial pressures, and regulatory oversight have increased the need to create improved mechanisms for performance measurement, quality management tracking, and outcomes-based research. The Anesthesia Quality Institute (AQI) has established the National Anesthesia Clinical Outcomes Registry (NACOR) to support these requirements for a wide-range of customers including individual anesthesiologists, anesthesia practices, hospitals, and credentialing agencies. Concurrently, the availability of increased digital sources of healthcare data make it possible to capture massive quantities of data in a more efficient and cost-effective manner than ever before. With NACOR, AQI has established a user-friendly, automated process to effectively and efficiently collect a wide-range of anesthesia-related data directly from anesthesia practices. This review will examine the issues guiding the evolution of NACOR as well as some potential pitfalls in its growth and usage.

scholarly journals Mobile cloud computing in smart healthcare Applications

2021 ◽  
Vol I (I) ◽  
Author(s):  
Kavitha N
Keyword(s):  
Cloud Computing ◽  
Mobile Cloud Computing ◽  
Critical Role ◽  
Cost Effective ◽  
Mobile Cloud ◽  
Healthcare Applications ◽  
Related Data ◽  
Healthcare Data ◽  
Smart Healthcare ◽  
Effective Manner

For urban residents, the Smart Healthcare idea is increasingly prevalent. This service's primary purpose is to provide patients with healthcare data. Using mobile communication and sharing in real time is necessary. Data processing and analysis are all part of this. As a result, cloud computing allows individuals to connect and access healthcare-related data. Data-related tasks like as sharing, processing, and analysis may be offloaded to mobile users for patients via mobile cloud devices, which can play a critical role in mobile cloud computing. Using this service, hospitals and clinics will be able to provide smart healthcare to their patients in a cost-effective manner. The usage of cloud computing will guarantee that patients get high-quality service.

Enterprise Crowdsourcing Platform to Improve HR Workflow

2020 ◽  
Vol 9 (5) ◽  
pp. 5-8 ◽  
Author(s):  
G. Zuev
Keyword(s):  
Large Scale ◽  
Best Practice ◽  
Cost Effective ◽  
Hr Management ◽  
Practical Project ◽  
Effective Manner ◽  
Wide Range ◽  
Hr Managers ◽  
Short Time ◽  
Small Parts

Crowdsourcing technologies may solve a wide range of business issues: improve efficiency of HR management, increase customer loyalty and maximize economic efficiency of whole enterprise. The recent years best practice has shown how crowdsourcing is gaining particular relevance of human resource management, allowing HR managers to resolve organization relevant problems in quick and cost-effective manner. Important advantage of crowdsourcing сomes from his main ability: decomposition of tasks into small parts and the ability to perform it’s remotely, via Internet. Thanks to this, not only large corporations, but also small and medium-sized businesses can execute a large-scale projects in a short time. This article discusses the main approaches and principles of practical project management via crowdsourcing platforms, using as the example “Beorg Smart Vision” solution.

scholarly journals Novel Approach for Characterizing Ubiquitin E3 Ligase Function

2010 ◽  
Vol 15 (10) ◽  
pp. 1220-1228 ◽  
Author(s):  
Jeffrey G. Marblestone ◽  
K. G. Suresh Kumar ◽  
Michael J. Eddins ◽  
Craig A. Leach ◽  
David E. Sterner ◽  
...  
Keyword(s):  
Drug Discovery ◽  
High Throughput Screening ◽  
E3 Ligase ◽  
Cost Effective ◽  
Ubiquitin Proteasome System ◽  
Dependent Manner ◽  
Ubiquitin Chain ◽  
E3 Ligases ◽  
Effective Manner ◽  
Wide Range

The ubiquitin-proteasome system is central to the regulation of numerous cellular events, and dysregulation may lead to disease pathogenesis. E3 ubiquitin ligases typically function in concert with E1 and E2 enzymes to recruit specific substrates, thereby coordinating their ubiquitylation and subsequent proteasomal degradation or cellular activity. E3 ligases have been implicated in a wide range of pathologies, and monitoring their activity in a rapid and cost-effective manner would be advantageous in drug discovery. The relative lack of high-throughput screening (HTS)–compliant E3 ligase assays has significantly hindered the discovery of E3 inhibitors. Herein, the authors describe a novel HTS-compliant E3 ligase assay platform that takes advantage of a ubiquitin binding domain’s inherent affinity for polyubiquitin chains, permitting the analysis of ubiquitin chain formation in an E3 ligase-dependent manner. This assay has been used successfully with members of both the RING and HECT families, demonstrating the platform’s broad utility for analyzing a wide range of E3 ligases. The utility of the assay platform is demonstrated by the identification of inhibitors of the E3 ligase CARP2. As the number of E3 ligases associated with various disease states increases, the ability to quantitate the activity of these enzymes in an expeditious manner becomes imperative in drug discovery.

Qualification of Procedures for Welding Onto In-Service Pipelines

2002 ◽  
Author(s):  
William A. Bruce
Keyword(s):  
Pipe Wall ◽  
Cost Effective ◽  
Environmental Benefits ◽  
Hydrogen Cracking ◽  
Welding Arc ◽  
Trade Offs ◽  
Effective Manner ◽  
Wide Range ◽  
Fast Cooling ◽  
Hydrogen Level

When welding onto an in-service pipeline, to facilitate a repair or to install a branch connection using the “hot tapping” technique, two risks need to be considered. The first is the risk of burnthrough, where the welding arc causes the pipe wall to be penetrated allowing the contents to escape. The second is the risk of hydrogen cracking that arises from the fast cooling rates that tend to be produced by the ability of the flowing contents to remove heat from the pipe wall. To prevent hydrogen cracking, at least one of the three conditions necessary for its occurrence must be eliminated. Beyond the use of low-hydrogen electrodes to minimize hydrogen levels, it is prudent to develop and use procedures that minimize the formation of crack susceptible microstructures. This paper reviews existing methods for selecting parameters and qualifying procedures for welding onto in-service pipelines. HAZ hardness is an indicator of the susceptibility of a microstructure to cracking. A widely-used value below which it is generally agreed that hydrogen cracking is not expected is 350 HV. Unfortunately, there is no one hardness level above which the risk of hydrogen cracking becomes unacceptable. This paper also describes the development of a hardness evaluation criterion that can be used to quantify the trade-offs that can be made between HAZ hardness, hydrogen level, and chemical composition. Finally, the results of a recently-completed group-sponsored project, where procedures for welding onto in-service pipelines were developed over a wide range of conditions, are also reviewed. The results can be used to select an appropriate procedure that is resistant to hydrogen cracking for a particular application. The use of these results allows in-service welding to be carried out in a safe, cost-effective manner, allowing both economic and environmental benefits to be realized by avoiding pipeline shutdown and interruption of service.

scholarly journals Pooled enrichment sequencing identifies diversity and evolutionary pressures at NLR resistance genes within a wild tomato population.

2016 ◽  
Author(s):  
Remco Stam ◽  
Daniela Scheikl ◽  
Aurelien Tellier
Keyword(s):  
Balancing Selection ◽  
Full Range ◽  
Copy Number Variants ◽  
Cost Effective ◽  
Pathogen Resistance ◽  
Frequency Spectra ◽  
Wild Tomato ◽  
Wild Tomato Species ◽  
Effective Manner ◽  
Wide Range

Nod-like Receptors (NLRs) are Nucleotide-binding domain and Leucine rich Repeats (NB-LRR)-containing proteins that are important in plant resistance signaling. Many of the known pathogen Resistance (R)-genes in plants are NLRs and they can recognise directly or indirectly pathogen molecules. As such, divergence and copy number variants at these genes is found to be high between species. Within populations, positive and balancing selection are to be expected if plants coevolve with their pathogens. In order to understand the complexity of R-gene coevolution in wild non-model species, it is necessary to identify the full range of NLRs and infer their evolutionary history. Here we investigate and reveal polymorphism occurring at 220 NLR genes within one population of the partially selfing wild tomato species S. pennellii. We use a combination of enrichment sequencing and pooling of ten individuals, to specifically sequence NLR genes in a resource and cost-effective manner. We focus on the effects which different of mapping and SNP calling software and settings have on calling polymorphisms in customized pooled samples. Our results are accurately verified using Sanger sequencing of polymorphic gene fragments. Our results indicate that some NLRs, namely 13 out of 220, have maintained polymorphism within our S. pennellii population. These genes show a wide range of πN/ πs ratios and differing site frequency spectra. We compare our observed rate of heterozygosity to expectations for this selfing and bottlenecked population. We conclude that our method enables us to pinpoint NLR genes which have experienced natural selection in their habitat.

scholarly journals In-house Reverse transcriptase polymerase chain reaction for detection of SARS-CoV2 with increased Sensitivity

2021 ◽  
Author(s):  
Manash Jyoti Kalita ◽  
Kalpajit Dutta ◽  
Gautam Hazarika ◽  
Ridip Dutta ◽  
Simanta Kalita ◽  
...  
Keyword(s):  
Multiplex Pcr ◽  
Real Time ◽  
Cost Effective ◽  
Sybr Green ◽  
Rdrp Gene ◽  
Green Approach ◽  
Resource Limited ◽  
Effective Manner ◽  
Wide Range ◽  
Primer Sets

Abstract Background:With the increasing COVID-19 infection worldwide, economization of the existing RT-PCR based detection assay becomes the need of the hour. Methods: An assessment of optimal PCR conditions for simultaneous amplification for E, S and RdRp gene of SARS-CoV-2 has been made using both fast traditional and multiplex real time PCR using same primer sets. All variables of practical value were studied by amplifying known target-sequences from ten-fold dilutions of archived positive samples of COVID-19. Results: The designed primers for amplification of E, S and RdRp gene of SARS-Cov-2 in single tube Multiplex PCR amplifications have shown efficient amplification of the target region in 37 minutes using thermal cyclers and 169 minutes with HRM based Real time detection using SYBR green master mix, over a wide range of template concentration, and the results were in good concordance with the commercially available detection kits. Conclusion: This fast HRM based Real time multiplex PCR with SYBR green approach offers rapid and sensitive detection of SARS-CoV-2 in a cost effective manner apart from the added advantage of primer pair’s compatibility for use in Traditional multiplex PCR, which offers extended applicability of the assay protocol in resource limited setting.

Enhancing the Economic Competitiveness of Concentrating Solar Power Plants Through an Innovative Integrated Solar-Combined Cycle With Thermal Energy Storage

2014 ◽  
Author(s):  
Rafael Guédez ◽  
James Spelling ◽  
Björn Laumert
Keyword(s):  
Power Plant ◽  
Gas Turbine ◽  
Power Plants ◽  
Solar Power ◽  
Cost Effective ◽  
Combined Cycle ◽  
Trade Offs ◽  
Effective Manner ◽  
Wide Range ◽  
Novel Concept

The present work deals with the thermoeconomic analysis of an innovative combined power cycle consisting of a molten-salt solar tower power plant with storage supported by additional heat provided from the exhaust of a topping gas-turbine unit. A detailed dynamic model has been elaborated using an in house simulation tool that simultaneously encompasses meteorological, demand and price data. A wide range of possible designs are evaluated in order to show the trade-offs between the objectives of achieving sustainable and economically competitive designs. Results show that optimal designs of the novel concept are a promising cost-effective hybrid option that can successfully fulfill both the roles of a gas peaker plant and a baseload solar power plant in a more effective manner. Moreover, designs are also compared against conventional combined cycle gas turbine power plants and it is shown that, under specific peaking operating strategies, the innovative concept can not only perform better from an environmental standpoint but also economically.

Enhancing the Economic Competitiveness of Concentrating Solar Power Plants Through an Innovative Integrated Solar-Combined Cycle With Thermal Energy Storage

2015 ◽  
Vol 137 (4) ◽  
Author(s):  
Rafael Guédez ◽  
James Spelling ◽  
Björn Laumert
Keyword(s):  
Power Plant ◽  
Gas Turbine ◽  
Power Plants ◽  
Solar Power ◽  
Cost Effective ◽  
Combined Cycle ◽  
Trade Offs ◽  
Effective Manner ◽  
Wide Range ◽  
Novel Concept

The present work deals with the thermo-economic analysis of an innovative combined power cycle consisting of a molten-salt solar tower power plant with storage supported by additional heat provided from the exhaust of a topping gas-turbine unit. A detailed dynamic model has been elaborated using an in house simulation tool that simultaneously encompasses meteorological, demand and price data. A wide range of possible designs are evaluated in order to show the trade-offs between the objectives of achieving sustainable and economically competitive designs. Results show that optimal designs of the novel concept are a promising cost-effective hybrid option that can successfully fulfill both the roles of a gas peaker plant and a baseload solar power plant in a more effective manner. Moreover, designs are also compared against conventional combined cycle gas turbine (CCGT) power plants and it is shown that, under specific peaking operating strategies (P-OSs), the innovative concept cannot only perform better from an environmental standpoint but also economically.

scholarly journals Design and Implementation of Secure and Efficient Cloud Centric Smart Health Care System

2021 ◽  
pp. 222-225
Author(s):  
Manikandan B ◽  
Aanisha A ◽  
Dinesh Kumar K ◽  
Sowdhamma S ◽  
VeeraKabilan R
Keyword(s):  
Data Security ◽  
Cost Effective ◽  
Data Access ◽  
Medical Data ◽  
Secret Key ◽  
Security Issues ◽  
Healthcare Environment ◽  
Effective Manner ◽  
Identity Based ◽  
User Friendly

In modern healthcare environment provide more user-friendly services at less time and in cost -effective manner. However, it causes data security issues on Electronic Health Record (EHR) transactions. The most challenging issue while handling the medical data is unauthorized accessing by unknown person. In this paper, a secure medical data access is carried out using Identity based proxy re-encryption system. Initially, patient has to register and upload the data in the cloud using the identity based proxy re-encryption system. Then the doctor will access the document using their respective identity and request for it, to get the secret key. This provides data confidentiality, integrity, and reduce the computation cost, while handling the documents in cloud.

Sign in / Sign up

Export Citation Format

Share Document