Parameter Estimation of Nonlinear Biomedical Systems Using Extended Kalman Filter Algorithm

2018 ◽  
pp. 690-713
Author(s):  
Kamalanand Krishnamurthy

Parameter estimation is a central issue in mathematical modelling of biomedical systems and for the development of patient specific models. The technique of estimating parameters helps in obtaining diagnostic information from computational models of biological systems. However, in most of the biomedical systems, the estimation of model parameters is a challenging task due to the nonlinearity of mathematical models. In this chapter, the method of estimation of nonlinear model parameters from measurements of state variables, using the extended Kalman filter, is extensively explained using an example of the three-dimensional model of the HIV/AIDS system.

Author(s):  
Kamalanand Krishnamurthy

Parameter estimation is a central issue in mathematical modelling of biomedical systems and for the development of patient specific models. The technique of estimating parameters helps in obtaining diagnostic information from computational models of biological systems. However, in most of the biomedical systems, the estimation of model parameters is a challenging task due to the nonlinearity of mathematical models. In this chapter, the method of estimation of nonlinear model parameters from measurements of state variables, using the extended Kalman filter, is extensively explained using an example of the three-dimensional model of the HIV/AIDS system.


Author(s):  
Jan Vidar Grindheim ◽  
Inge Revhaug ◽  
Egil Pedersen

A finite difference method (FDM) solving the coupled partial differential equations governing three-dimensional (3D) motions of a towed underwater cable has been implemented in a combined ensemble Kalman filter (EnKF) and ensemble Kalman smoother (EnKS), as a new approach to combined state and parameter estimation for towed underwater cables. A simulation study of the method applied to a seismic streamer has been performed. Cable state variables as well as model parameters are estimated. Parameters estimated are crossline ocean current varying with time as well as cable tangential drag coefficient. The presented results indicate that the method is able to estimate state as well as parameters for seismic streamers.


Sensors ◽  
2019 ◽  
Vol 19 (19) ◽  
pp. 4174 ◽  
Author(s):  
Rodrigo Munguía ◽  
Sarquis Urzua ◽  
Antoni Grau

This work presents a method for estimating the model parameters of multi-rotor unmanned aerial vehicles by means of an extended Kalman filter. Different from test-bed based identification methods, the proposed approach estimates all the model parameters of a multi-rotor aerial vehicle, using a single online estimation process that integrates measurements that can be obtained directly from onboard sensors commonly available in this kind of UAV. In order to develop the proposed method, the observability property of the system is investigated by means of a nonlinear observability analysis. First, the dynamic models of three classes of multi-rotor aerial vehicles are presented. Then, in order to carry out the observability analysis, the state vector is augmented by considering the parameters to be identified as state variables with zero dynamics. From the analysis, the sets of measurements from which the model parameters can be estimated are derived. Furthermore, the necessary conditions that must be satisfied in order to obtain the observability results are given. An extensive set of computer simulations is carried out in order to validate the proposed method. According to the simulation results, it is feasible to estimate all the model parameters of a multi-rotor aerial vehicle in a single estimation process by means of an extended Kalman filter that is updated with measurements obtained directly from the onboard sensors. Furthermore, in order to better validate the proposed method, the model parameters of a custom-built quadrotor were estimated from actual flight log data. The experimental results show that the proposed method is suitable to be practically applied.


2017 ◽  
Vol 65 (4) ◽  
pp. 479-488 ◽  
Author(s):  
A. Boboń ◽  
A. Nocoń ◽  
S. Paszek ◽  
P. Pruski

AbstractThe paper presents a method for determining electromagnetic parameters of different synchronous generator models based on dynamic waveforms measured at power rejection. Such a test can be performed safely under normal operating conditions of a generator working in a power plant. A generator model was investigated, expressed by reactances and time constants of steady, transient, and subtransient state in the d and q axes, as well as the circuit models (type (3,3) and (2,2)) expressed by resistances and inductances of stator, excitation, and equivalent rotor damping circuits windings. All these models approximately take into account the influence of magnetic core saturation. The least squares method was used for parameter estimation. There was minimized the objective function defined as the mean square error between the measured waveforms and the waveforms calculated based on the mathematical models. A method of determining the initial values of those state variables which also depend on the searched parameters is presented. To minimize the objective function, a gradient optimization algorithm finding local minima for a selected starting point was used. To get closer to the global minimum, calculations were repeated many times, taking into account the inequality constraints for the searched parameters. The paper presents the parameter estimation results and a comparison of the waveforms measured and calculated based on the final parameters for 200 MW and 50 MW turbogenerators.


Author(s):  
Christopher J. Arthurs ◽  
Nan Xiao ◽  
Philippe Moireau ◽  
Tobias Schaeffter ◽  
C. Alberto Figueroa

AbstractA major challenge in constructing three dimensional patient specific hemodynamic models is the calibration of model parameters to match patient data on flow, pressure, wall motion, etc. acquired in the clinic. Current workflows are manual and time-consuming. This work presents a flexible computational framework for model parameter estimation in cardiovascular flows that relies on the following fundamental contributions. (i) A Reduced-Order Unscented Kalman Filter (ROUKF) model for data assimilation for wall material and simple lumped parameter network (LPN) boundary condition model parameters. (ii) A constrained least squares augmentation (ROUKF-CLS) for more complex LPNs. (iii) A “Netlist” implementation, supporting easy filtering of parameters in such complex LPNs. The ROUKF algorithm is demonstrated using non-invasive patient-specific data on anatomy, flow and pressure from a healthy volunteer. The ROUKF-CLS algorithm is demonstrated using synthetic data on a coronary LPN. The methods described in this paper have been implemented as part of the CRIMSON hemodynamics software package.


2018 ◽  
Vol 8 (11) ◽  
pp. 2028 ◽  
Author(s):  
Xin Lai ◽  
Dongdong Qiao ◽  
Yuejiu Zheng ◽  
Long Zhou

The popular and widely reported lithium-ion battery model is the equivalent circuit model (ECM). The suitable ECM structure and matched model parameters are equally important for the state-of-charge (SOC) estimation algorithm. This paper focuses on high-accuracy models and the estimation algorithm with high robustness and accuracy in practical application. Firstly, five ECMs and five parameter identification approaches are compared under the New European Driving Cycle (NEDC) working condition in the whole SOC area, and the most appropriate model structure and its parameters are determined to improve model accuracy. Based on this, a multi-model and multi-algorithm (MM-MA) method, considering the SOC distribution area, is proposed. The experimental results show that this method can effectively improve the model accuracy. Secondly, a fuzzy fusion SOC estimation algorithm, based on the extended Kalman filter (EKF) and ampere-hour counting (AH) method, is proposed. The fuzzy fusion algorithm takes advantage of the advantages of EKF, and AH avoids the weaknesses. Six case studies show that the SOC estimation result can hold the satisfactory accuracy even when large sensor and model errors exist.


Electronics ◽  
2018 ◽  
Vol 7 (11) ◽  
pp. 321 ◽  
Author(s):  
Xin Lai ◽  
Wei Yi ◽  
Yuejiu Zheng ◽  
Long Zhou

In this paper, a novel model parameter identification method and a state-of-charge (SOC) estimator for lithium-ion batteries (LIBs) are proposed to improve the global accuracy of SOC estimation in the all SOC range (0–100%). Firstly, a subregion optimization method based on particle swarm optimization is developed to find the optimal model parameters of LIBs in each subregion, and the optimal number of subregions is investigated from the perspective of accuracy and computation time. Then, to solve the problem of a low accuracy of SOC estimation caused by large model error in the low SOC range, an improved extended Kalman filter (IEKF) algorithm with variable noise covariance is proposed. Finally, the effectiveness of the proposed methods are verified by experiments on two kinds of batteries under three working cycles, and case studies show that the proposed IEKF has better accuracy and robustness than the traditional extended Kalman filter (EKF) in the all SOC range.


2002 ◽  
Vol 12 (05) ◽  
pp. 411-424
Author(s):  
SHOULING HE

In this paper multilayer neural networks (MNNs) are used to control the balancing of a class of inverted pendulums. Unlike normal inverted pendulums, the pendulum discussed here has two degrees of rotational freedom and the base-point moves randomly in three-dimensional space. The goal is to apply control torques to keep the pendulum in a prescribed position in spite of the random movement at the base-point. Since the inclusion of the base-point motion leads to a non-autonomous dynamic system with time-varying parametric excitation, the design of the control system is a challenging task. A feedback control algorithm is proposed that utilizes a set of neural networks to compensate for the effect of the system's nonlinearities. The weight parameters of neural networks updated on-line, according to a learning algorithm that guarantees the Lyapunov stability of the control system. Furthermore, since the base-point movement is considered unmeasurable, a neural inverse model is employed to estimate it from only measured state variables. The estimate is then utilized within the main control algorithm to produce compensating control signals. The examination of the proposed control system, through simulations, demonstrates the promise of the methodology and exhibits positive aspects, which cannot be achieved by the previously developed techniques on the same problem. These aspects include fast, yet well-maintained damped responses with reasonable control torques and no requirement for knowledge of the model or the model parameters. The work presented here can benefit practical problems such as the study of stable locomotion of human upper body and bipedal robots.


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