scholarly journals Paroxysmal Atrial Fibrillation: An Independent Risk Factor for Prothrombotic Conditions

2020 ◽  
Vol 13 (2) ◽  
Author(s):  
Dhanunjaya Lakkireddy
Keyword(s):  
Atrial Fibrillation ◽  
Risk Factor ◽  
Paroxysmal Atrial Fibrillation ◽  
Independent Risk Factor

scholarly journals Association between functional mitral regurgitation and recurrence of paroxysmal atrial fibrillation following catheter ablation: a prospective cohort study

2021 ◽  
Vol 49 (5) ◽  
pp. 030006052110143
Author(s):  
Fusheng Ke ◽  
Yinhui Huang ◽  
Zhexiu Jin ◽  
Lei Huang ◽  
Qiang Xiong ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Risk Factor ◽  
Cohort Study ◽  
Catheter Ablation ◽  
Mitral Regurgitation ◽  
Confidence Interval ◽  
Paroxysmal Atrial Fibrillation ◽  
Prospective Cohort ◽  
Radiofrequency Catheter Ablation ◽  
Functional Mitral Regurgitation

Objective The present study aimed to investigate the effect of functional mitral regurgitation (FMR) on recurrence of paroxysmal atrial fibrillation (PAF) in patients undergoing radiofrequency catheter ablation. Methods This prospective cohort study comprised 107 patients with PAF. The patients were divided into the FMR and non-FMR groups. FMR was assessed by Doppler echocardiography before index ablation. All patients initially underwent circumferential pulmonary vein isolation (CPVI) and were followed up for 12 months after ablation. PAF, atrial tachycardia, or atrial flutter served as the endpoint indicator. Results The median duration of PAF was 24 (3–60) months. Binary logistic univariate and multivariate analyses showed that FMR was not a risk factor for recurrence of catheter ablation for PAF (hazard ratio=0.758, 95% confidence interval: 0.191–3.004; hazard ratio=0.665, 95% confidence interval: 0.134–3.300, respectively). Kaplan–Meier analysis showed no significant difference in the recurrence rate between the groups. Fifteen (15/107, 14%) cases of PAF were triggered by the pulmonary vein. Three (3/107, 2.8%) cases of PAF were triggered by the superior vena cava. Conclusions FMR is not an independent risk factor for predicting recurrence of catheter ablation for PAF. FMR does not affect patients undergoing radiofrequency catheter ablation for PAF.

Should the Presence or Extent of Coronary Artery Disease be Quantified in the CHA2DS2-VASc Score in Atrial Fibrillation? A Report from the Western Denmark Heart Registry

2018 ◽  
Vol 118 (12) ◽  
pp. 2162-2170 ◽  
Author(s):  
Kamilla Steensig ◽  
Kevin Olesen ◽  
Troels Thim ◽  
Jens Nielsen ◽  
Svend Jensen ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Coronary Artery Disease ◽  
Risk Factor ◽  
Coronary Artery ◽  
Coronary Angiography ◽  
Ischaemic Stroke ◽  
Independent Risk Factor ◽  
Oral Anticoagulants ◽  
Increased Risk ◽  
Artery Disease

Background Patients with atrial fibrillation (AF) have an increased risk of ischaemic stroke. The risk can be predicted by the CHA2DS2-VASc score, in which the vascular component refers to previous myocardial infarction, peripheral artery disease and aortic plaque, whereas coronary artery disease (CAD) is not included. Objectives This article explores whether CAD per se or extent provides independent prognostic information of future stroke among patients with AF. Materials and Methods Consecutive patients with AF and coronary angiography performed between 2004 and 2012 were included. The endpoint was a composite of ischaemic stroke, transient ischaemic attack and systemic embolism. The risk of ischaemic events was estimated according to the presence and extent of CAD. Incidence rate ratios (IRR) were calculated in reference to patients without CAD and adjusted for parameters included in the CHA2DS2-VASc score and treatment with anti-platelet agents and/or oral anticoagulants. Results Of 96,430 patients undergoing coronary angiography, 12,690 had AF. Among patients with AF, 7,533 (59.4%) had CAD. Mean follow-up was 3 years. While presence of CAD was an independent risk factor for the composite endpoint (adjusted IRR, 1.25; 1.06–1.47), extent of CAD defined as 1-, 2-, 3- or diffuse vessel disease did not add additional independent risk information. Conclusion Presence, but not extent, of CAD was an independent risk factor of the composite thromboembolic endpoint beyond the components already included in the CHA2DS2-VASc score. Consequently, we suggest that significant angiographically proven CAD should be included in the vascular disease criterion in the CHA2DS2-VASc score.

scholarly journals Atrial fibrillation as an independent risk factor for stroke: the Framingham Study.

Stroke ◽  
1991 ◽  
Vol 22 (8) ◽  
pp. 983-988 ◽  
Author(s):  
P A Wolf ◽  
R D Abbott ◽  
W B Kannel
Keyword(s):  
Atrial Fibrillation ◽  
Risk Factor ◽  
Independent Risk Factor ◽  
Framingham Study

scholarly journals CAD Is an Independent Risk Factor for Stroke Among Patients With Atrial Fibrillation

2018 ◽  
Vol 72 (20) ◽  
pp. 2540-2542 ◽  
Author(s):  
Kamilla Steensig ◽  
Kevin K.W. Olesen ◽  
Troels Thim ◽  
Jens C. Nielsen ◽  
Svend E. Jensen ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Risk Factor ◽  
Independent Risk Factor

scholarly journals Impairment of Pulmonary Function is an Independent Risk Factor for Atrial Fibrillation: The Takahata Study

2011 ◽  
Vol 8 (7) ◽  
pp. 514-522 ◽  
Author(s):  
Yoko Shibata ◽  
Tetsu Watanabe ◽  
Daisuke Osaka ◽  
Shuichi Abe ◽  
Sumito Inoue ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Risk Factor ◽  
Pulmonary Function ◽  
Independent Risk Factor
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