Confocal Raman Spectroscopic Analysis of Phase Transformation and Residual Stresses in Ce-TZP/Al2O3 Nanocomposite for Biomedical Applications

Author(s):  
Kiyotaka Yamada ◽  
Masahiro Nawa ◽  
Giuseppe Pezzotti
Author(s):  
Giuseppe Pezzotti ◽  
Ian C. Clarke ◽  
C. Jobe ◽  
T. Donaldson ◽  
K. Yamamoto ◽  
...  

2007 ◽  
Vol 330-332 ◽  
pp. 373-376 ◽  
Author(s):  
Kiyotaka Yamada ◽  
Masahiro Nawa ◽  
Giuseppe Pezzotti

Zirconia ceramics have been widely used for new generation of bearing materials in biomedical applications. In this context, a zirconia-matrix, stabilized with cerium oxide and dispersed with fine alumina particles (Ce-TZP/Al2O3 nanocomposite) was recently developed and this material experienced significant improvements in both fracture toughness and strength above the standard mechanical performance of monolithic zirconia. In this paper, we used confocal Raman spectroscopy to provide quantitative assessments with high spatial resolution of phase structure and residual stress fields developed in the Ce-TZP/Al2O3 nanocomposite. According to confocal Raman spectroscopy, we have directly visualized patterns of phase transformation and residual stress fields stored on the very surface of the material around an indentation print. These spectroscopic assessments may open a perspective in understanding the micromechanical behavior of the Ce-TZP/Al2O3 nanocomposite when subjected to local surface impingement and shocks.


2006 ◽  
Vol 309-311 ◽  
pp. 1211-1214 ◽  
Author(s):  
Giuseppe Pezzotti ◽  
Ian C. Clarke ◽  
C. Jobe ◽  
T. Donaldson ◽  
Kengo Yamamoto ◽  
...  

A survey of confocal Raman/fluorescence microprobe spectroscopic techniques is presented with emphasis placed on surface analysis of artificial hip joints. Suitable instrumental configurations are first explained in some details in order to describe the versatility of the spectroscopic microprobes to biomedical materials analyses. Then, these notions, which represent the foundation for structural and mechanical analyses of joint surfaces, are applied to selected cases of paramount importance in hip arthroplasty.


Author(s):  
Shuo Zhang ◽  
Frederieke A. M. van der Mee ◽  
Roel J. Erckens ◽  
Carroll A. B. Webers ◽  
Tos T. J. M. Berendschot

AbstractIn this report we present a confocal Raman system to identify the unique spectral features of two proteins, Interleukin-10 and Angiotensin Converting Enzyme. Characteristic Raman spectra were successfully acquired and identified for the first time to our knowledge, showing the potential of Raman spectroscopy as a non-invasive investigation tool for biomedical applications.


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