Influence of Training with and without Reward on Visual Inspector’s Performance in 3 Dimension Model

2011 ◽  
Vol 110-116 ◽  
pp. 2911-2917
Author(s):  
Anucha Watanapa ◽  
S. Kaewkuekool ◽  
S. Suksakulchai
Keyword(s):  
3D Model ◽  
Statistical Significance ◽  
Feedback Training ◽  
Reward Group ◽  
Speed And Accuracy

This research was aimed to improve an inspector’s performance on the training through 3D model by motivation technique. The subjects were divided into 3 groups; the control, the feedback training, and feedback training with reward groups. The subjects participated in the last group would get rewards or punishments such as money given or deducted during the test with 3D model software with Thai characters and Roman characters representing defects and backgrounds. According to the experiment, the performance in terms of speed and accuracy in detecting defects in training with reward group increased. In other words, feedback with motivation training could make visual inspectors spend less time detecting defects to their minimum because motivation attracted them in the experiment. Therefore, the time spent seeking defects in this group decreased. The performance of training with reward group is higher than other groups which showed the statistical significance at the .01 level.

scholarly journals Integrated Ligand and Structure-Based Investigation of Structural Requirements for Silent Information Regulator 1 (SIRT1) Activation

2019 ◽  
Vol 18 (27) ◽  
pp. 2313-2324
Author(s):  
Amit K. Gupta ◽  
Sun Choi
Keyword(s):  
3D Model ◽  
Therapeutic Agent ◽  
Statistical Significance ◽  
3D Qsar ◽  
Qsar Model ◽  
Hydrogen Bond Acceptor ◽  
High Statistical Significance ◽  
Qsar Models ◽  
Silent Information Regulator 1 ◽  
2D And 3D

A series of imidazothiazole and oxazolopyridine derivatives as human Silent Information Regulator 1 (SIRT1) activators were subjected to the integrated 2D and 3D QSAR approaches. The derived 3D QSAR models yielded high cross-validated q2 values of 0.682 and 0.628 for CoMFA and CoMSIA, respectively. The non-cross validated values of r2 training = 0.89; predictive r2 test = 0.69 for CoMFA and r2=0.87; predictive r2 test =0.67 for CoMSIA reflected the statistical significance of the developed model. The steric, electrostatic, hydrophobic and hydrogen bond acceptor interactions have been found important in describing the variation in human SIRT1 activation. Further, 2D QSAR model for the same dataset yielded high statistical significance and derived 2D model’s parameters corroborated with the 3D model in terms of features. Derived model was also validated by the crystal structure of active conformation of SIRT1. Developed models may be useful for the identification of potential novel human SIRT1 activators as a therapeutic agent.

scholarly journals A Comparison of the Accuracy of WATCHMAN and WATCHMAN FLX Device Sizing between CT, TEE, and Patient Specific 3D Models

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Ivette Troitino ◽  
T. Eric White ◽  
John Lozo
Keyword(s):  
3D Model ◽  
Intraoperative Complications ◽  
Statistical Significance ◽  
3D Models ◽  
Ct Scans ◽  
Orifice Diameter ◽  
Patient Specific ◽  
Accuracy Of Measurements ◽  
Device Size ◽  
Actual Size

Background and Hypothesis: In patients with Atrial fibrillation (AF), the Left Atrial Appendage (LAA) is the most common site of thrombus formation. The LAA occlusion procedure using the WATCHMAN device implant is an alternative for stroke prevention in AF patients. Transesophageal echocardiogram (TEE) and Computed tomography (CT) scans aid in measuring the LAA to predict implant device sizes. However, due to varying LAA anatomy and limited spatial resolution, the current imaging techniques often predict one of two sized devices. The objective of this retrospective study is to compare the accuracy of measurements made preoperatively of the LAA with those on 3D models to determine if they can be used in preoperative planning. We hypothesize 3D models will be more accurate in predicting device size and any anatomical impediments than traditional TEE planning. Project Methods: There were 21 subjects selected who underwent the WATCHMAN FLX procedure at Parkview Heart Institute in 2021. 3D models of LAA were created from CT scans using a Form 2 3D printer. The device sizes predicted for the procedure were determined from Boston Scientific FLX guidelines based on the maximum LAA orifice diameter from TEE, CT, and 3D models. Results: Two-proportion z-test between the 3D model predicted sizes to the actual size deployed demonstrated no statistical significance (p=0.298) demonstrating no difference between 3D model predicted sizes and actual size deployed. Two-proportion z-test between TEE vs actual size and CT vs actual size demonstrated statistical significance, suggesting a difference between the group's predictions. 3D models predicted the accurate device size for 20/21(95%) subjects. TEE measurements of maximum orifice diameter were, on average, lower compared to CT and 3D model measurements. Conclusion and Potential Impact: 3D printed models provide the most accurate device size predictions and can be used to optimize presurgical planning while reducing intraoperative complications.

scholarly journals Verb processing in children with developmental language disorder

Logopedija ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 78-83
Author(s):  
Katarina Pavičić Dokoza
Keyword(s):  
Word Processing ◽  
Language Disorder ◽  
Statistical Significance ◽  
Developmental Language Disorder ◽  
Language Therapy ◽  
Verb Processing ◽  
The Difference ◽  
Semantic Errors ◽  
Speed Accuracy ◽  
Speed And Accuracy

Speed, accuracy, and type of errors during word processing in children with developmental language disorder (DLD) have often been in the focus of various lexical studies. Results of these studies are uniform: children with DLD show slow and less accurate processing. Less is known about the speed and accuracy of verb processing. Therefore, the aim of this study is to explore whether there are differences in the speed and accuracy of verb processing between children with DLD and their typical developing chronological peers (TDC) and younger, language age-matched peers (TDC-y), with special attention to the type of errors produced. The participants in this pilot study were 30 children between the ages of 7;11 and 11 years. Average age of children with DLD was 10;2; TDC children 9;9; and TDC-y children were 8,1. Research procedure included stimulus word presented in auditory form, and children’s task was to choose which one of the three presented pictures on computer screen represent the verb they just heard. Results showed no statistically significant differences regarding speed and accuracy between groups of participants. The difference in proportion of errors in picture selection task did not reach statistical significance when it comes to phonological mistakes, nor when it comes to semantic errors. However, the proportion of phonological errors had a tendency of highest scores in group of children with DLD, while proportion of semantic errors was highest in TDC-y. According to findings from this study, it seems important to emphasize the importance of phonological exercises parallel with exercises focused on vocabulary span in work with children with DLD. Number of exposures to the new word in children with DLD can play a significant role in speed of processing but it can also lead to overlearning affecting research outcomes. Children with DLD who participated in this study had been enrolled in speech and language therapy for several years. Future studies should, among other, also control this variable.

scholarly journals Integrated ligand and structure-based investigation of structural requirements for silent information regulator [SIRT1] activation

2018 ◽  
Author(s):  
Amit K. Gupta ◽  
Sun Choi
Keyword(s):  
3D Model ◽  
Therapeutic Agent ◽  
Statistical Significance ◽  
3D Qsar ◽  
Qsar Model ◽  
Active Conformation ◽  
Hydrogen Bond Acceptor ◽  
High Statistical Significance ◽  
Qsar Models ◽  
2D And 3D

AbstractA series of imidazothiazole and oxazolopyridine derivatives as human silent information regulator (SIRT1) activators were subjected to the integrated 2D and 3D QSAR approaches. The derived 3D QSAR models yielded high cross validated q2 values of 0.682 and 0.628 for CoMFA and CoMSIA respectively. The non-cross validated correlation values of r2training = 0.89; predictive r2test = 0.69 for CoMFA and r2=0.87; predictive r2test =0.67 for CoMSIA reflected the statistical significance of the developed model. The steric, electrostatic, hydrophobic and hydrogen bond acceptor interactions have been found important in describing the variation in human SIRT1 activation. Further, 2D QSAR model for the same dataset yielded high statistical significance and derived 2D model’s parameters corroborated with 3D model in terms of features. The developed model was also validated through the available active conformation structure of SIRT1. Developed models may be useful for the identification of potential novel human SIRT1 activators as therapeutic agent.

Imaging molecules adsorbed onto electrodes under potential control by scanning probe microscopy

1991 ◽  
Vol 49 ◽  
pp. 376-377 ◽  
Author(s):  
N.J. Tao ◽  
J.A. DeRose ◽  
P.I. Oden ◽  
S.M. Lindsay
Keyword(s):  
Surface Charge ◽  
Environmental Effects ◽  
Scanning Probe Microscopy ◽  
Statistical Significance ◽  
Electrochemical Methods ◽  
Surface Structures ◽  
Scanning Probe ◽  
Potential Control ◽  
Afm Imaging ◽  
Special Circumstances

Clemmer and Beebe have pointed out that surface structures on graphite substrates can be misinterpreted as biopolymer images in STM experiments. We have been using electrochemical methods to react DNA fragments onto gold electrodes for STM and AFM imaging. The adsorbates produced in this way are only homogeneous in special circumstances. Searching an inhomogeneous substrate for ‘desired’ images limits the value of the data. Here, we report on a reversible method for imaging adsorbates. The molecules can be lifted onto and off the substrate during imaging. This leaves no doubt about the validity or statistical significance of the images. Furthermore, environmental effects (such as changes in electrolyte or surface charge) can be investigated easily.

Comparison of Auditory, Language, Memory, and Attention Abilities in Children With and Without Listening Difficulties

2020 ◽  
Vol 29 (4) ◽  
pp. 710-727
Author(s):  
Beula M. Magimairaj ◽  
Naveen K. Nagaraj ◽  
Alexander V. Sergeev ◽  
Natalie J. Benafield
Keyword(s):  
Auditory Processing ◽  
Short Term Memory ◽  
Group Differences ◽  
Long Term Memory ◽  
Short Term ◽  
Significant Group ◽  
Term Memory ◽  
Memory And Attention ◽  
Speed And Accuracy

Objectives School-age children with and without parent-reported listening difficulties (LiD) were compared on auditory processing, language, memory, and attention abilities. The objective was to extend what is known so far in the literature about children with LiD by using multiple measures and selective novel measures across the above areas. Design Twenty-six children who were reported by their parents as having LiD and 26 age-matched typically developing children completed clinical tests of auditory processing and multiple measures of language, attention, and memory. All children had normal-range pure-tone hearing thresholds bilaterally. Group differences were examined. Results In addition to significantly poorer speech-perception-in-noise scores, children with LiD had reduced speed and accuracy of word retrieval from long-term memory, poorer short-term memory, sentence recall, and inferencing ability. Statistically significant group differences were of moderate effect size; however, standard test scores of children with LiD were not clinically poor. No statistically significant group differences were observed in attention, working memory capacity, vocabulary, and nonverbal IQ. Conclusions Mild signal-to-noise ratio loss, as reflected by the group mean of children with LiD, supported the children's functional listening problems. In addition, children's relative weakness in select areas of language performance, short-term memory, and long-term memory lexical retrieval speed and accuracy added to previous research on evidence-based areas that need to be evaluated in children with LiD who almost always have heterogenous profiles. Importantly, the functional difficulties faced by children with LiD in relation to their test results indicated, to some extent, that commonly used assessments may not be adequately capturing the children's listening challenges. Supplemental Material https://doi.org/10.23641/asha.12808607

Clinical Success Using the Audio-Visual Feedback Training for Cluttering

2019 ◽  
Vol 4 (6) ◽  
pp. 1589-1594
Author(s):  
Yvonne van Zaalen ◽  
Isabella Reichel
Keyword(s):  
Visual Feedback ◽  
Clinical Success ◽  
Pause Duration ◽  
Digital Audio ◽  
Male Adolescents ◽  
Feedback Training ◽  
Positive Effects ◽  
Speech Monitoring ◽  
Adolescents And Adults

Purpose Among the best strategies to address inadequate speech monitoring skills and other parameters of communication in people with cluttering (PWC) is the relatively new but very promising auditory–visual feedback (AVF) training ( van Zaalen & Reichel, 2015 ). This study examines the effects of AVF training on articulatory accuracy, pause duration, frequency, and type of disfluencies of PWC, as well as on the emotional and cognitive aspects that may be present in clients with this communication disorder ( Reichel, 2010 ; van Zaalen & Reichel, 2015 ). Methods In this study, 12 male adolescents and adults—6 with phonological and 6 with syntactic cluttering—were provided with weekly AVF training for 12 weeks, with a 3-month follow-up. Data was gathered on baseline (T0), Week 6 (T1), Week 12 (T2), and after follow-up (T3). Spontaneous speech was recorded and analyzed by using digital audio-recording and speech analysis software known as Praat ( Boersma & Weenink, 2017 ). Results The results of this study indicated that PWC demonstrated significant improvements in articulatory rate measurements and in pause duration following the AVF training. In addition, the PWC in the study reported positive effects on their ability to retell a story and to speak in more complete sentences. PWC felt better about formulating their ideas and were more satisfied with their interactions with people around them. Conclusions The AVF training was found to be an effective approach for improving monitoring skills of PWC with both quantitative and qualitative benefits in the behavioral, cognitive, emotional, and social domains of communication.

Introduction to the Forum on Cluttering: Rays of Hope Shine Around the World

2019 ◽  
Vol 4 (6) ◽  
pp. 1566-1567
Author(s):  
Isabella Reichel
Keyword(s):  
Professional Preparation ◽  
Joint Effort ◽  
Feedback Training ◽  
Successful Communication ◽  
Self Help ◽  
The World ◽  
Common Thread ◽  
Evidence Based Treatments ◽  
Attention Performance ◽  
Self Help Groups

Purpose In the 10 years since the International Cluttering Association (ICA) was created, this organization has been growing in the scope of its initiatives, and in the variety of resources it makes available for people with cluttering (PWC). However, the awareness of this disorder and of the methods for its intervention remain limited in countries around the world. A celebration of the multinational and multicultural engagements of the ICA's Committee of the International Representatives is a common thread running through all the articles in this forum. The first article is a joint effort among international representatives from five continents and 15 countries, exploring various themes related to cluttering, such as awareness, research, professional preparation, intervention, and self-help groups. The second article, by Elizabeth Gosselin and David Ward, investigates attention performance in PWC. In the third article, Yvonne van Zaalen and Isabella Reichel explain how audiovisual feedback training can improve the monitoring skills of PWC, with both quantitative and qualitative benefits in cognitive, emotional, and social domains of communication. In the final article, Hilda Sønsterud examines whether the working alliance between the client and clinician may predict a successful cluttering therapy outcome. Conclusions Authors of this forum exchanged their expertise, creativity, and passion with the goal of solving the mystery of the disconcerting cluttering disorder with the hope that all PWC around the globe will have access to the most effective evidence-based treatments leading to blissful and successful communication.

Influence of Maternal Education on Food Consumption and Energy and Nutrient Intake in a Group of Pre-School Children from Madrid

2003 ◽  
Vol 73 (6) ◽  
pp. 439-445 ◽  
Author(s):  
Navia ◽  
Ortega ◽  
Requejo ◽  
Perea ◽  
López-Sobaler ◽  
...  
Keyword(s):  
Food Consumption ◽  
School Children ◽  
Food Habits ◽  
Nutrient Intake ◽  
Maternal Education ◽  
Statistical Significance ◽  
Dietary Adequacy ◽  
Consumption Energy ◽  
Maternal Educational Level ◽  
Energy And Nutrient Intake

A study was conducted on the influence of maternal education level on food consumption, energy and nutrient intake, and dietary adequacy in 110 pre-school children from Madrid, Spain. With increasing maternal education, children consumed more sugar (p < 0.05), fruit (p < 0.05), and fish (p < 0.05). Snacking was more frequent with decreasing maternal education (p < 0.05). Though statistical significance was not reached, the consumption of pre-cooked foods was greater among children of mothers educated to a higher level, a phenomenon probably related to the work situation of these women. With respect to dietary composition, no significant differences were found between groups for macronutrient, fiber and energy intakes, except for energy supplied by polyunsaturated fatty acids (PUFA), which was greater in the children of less educated women (p < 0.01). This is probably due to their greater consumption of sunflower seed oil. The diets of children belonging to well-educated mothers came closer to meeting the recommended intakes for folate, vitamin C, and iodine. It would seem that maternal educational level influences the food habits of children. Mothers with less education may require special advice in this area.

Use of vascular closure devices for endovascular interventions requiring a direct puncture of PETE grafts

VASA ◽  
2018 ◽  
Vol 47 (2) ◽  
pp. 119-124 ◽  
Author(s):  
Artur I. Milnerowicz ◽  
Aleksandra A. Milnerowicz ◽  
Marcin Protasiewicz ◽  
Wiktor Kuliczkowski
Keyword(s):  
Statistical Significance ◽  
Vascular Complications ◽  
Vascular Complication ◽  
Inguinal Region ◽  
Closure Device ◽  
Manual Compression ◽  
Direct Puncture ◽  
Endovascular Interventions ◽  
Vascular Closure Devices ◽  
Closure Group

Abstract. Background: Effectiveness of vascular closure devices during endovascular procedures requiring a direct puncture of a vascular prosthesis placed in the inguinal region is unknown. Patients and methods: The retrospective analysis included 134 patients with a history of polyethylene terephthalate (PETE) graft implantation in the inguinal region. In 20 (15 %) patients, haemostasis was achieved with manual compression, in 21 (16 %) with the StarClose™, and in 93 (69 %) with the AngioSeal™ device. Results: The incidence of vascular complications in the manual compression group was higher (at a threshold of statistical significance) than in the device closure group (45.0 vs. 24.5 %, p = 0.059). The difference was considered statistically significant when manual compression was compared with the AngioSeal™ closure group (45.0 vs. 13.9 %, p < 0.01). The vascular complication rate in the StarClose™ group was significantly higher than in the AngioSeal™ group (71.4 vs. 13.9 %, p < 0.000001). While haematomas were the only vascular complications observed after application of AngioSeal™, both haematomas and pseudoaneurysms were found in the StarClose™ group. Conclusions: The AngioSeal™ vascular closure device provides better local haemostasis than the StarClose™ device or manual compression during endovascular interventions requiring a direct puncture of PETE grafts

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