LinDOS: A Linear Distraction Osteogenesis Simulation System for Maxillofacial Surgery Based on FEM

2012 ◽  
Vol 195-196 ◽  
pp. 795-800
Author(s):  
Jun Feng ◽  
Xiao Dong Wang ◽  
Hong Wei Feng ◽  
Hong Tao Shang
Keyword(s):  
Distraction Osteogenesis ◽  
Preoperative Planning ◽  
Maxillofacial Surgery ◽  
Simulation System ◽  
Language Ability ◽  
Distribution Analysis ◽  
Serious Infection ◽  
System Reconstruction ◽  
Function Modules ◽  
Bone Transportation

Developmental craniofacial deformity often has serious infection on the patient's chewing, language ability, swallowing, breathing and other related functions. Currently, internal and linear Distraction Osteogenesis (DO) are main surgery solutions of bone transportation and recovery in clinic. In this paper, we present a computer system called LinDOS for maxillofacial system reconstruction and visualization, maxillofacial tissues stress distribution analysis, as well as linear distraction osteogenesis simulation. Both design architecture and the function modules of the system are described in detail. The system can be employed as an assistant tool of maxillofacial preoperative planning and postoperative prediction for maxillofacial surgeons.

A Simulation System of Radio Propagation Effect Evaluation Based on GIS

2014 ◽  
Vol 687-691 ◽  
pp. 3053-3057
Author(s):  
Hong Ming Wang ◽  
Jun Dong
Keyword(s):  
Wave Propagation ◽  
Radio Wave ◽  
Simulation System ◽  
Radio Wave Propagation ◽  
System Structure ◽  
Effect Evaluation ◽  
Propagation Effects ◽  
Function Modules ◽  
Gis System ◽  
Effects Assessment

Construction of wave propagation effects assessment simulation system based on GIS, for enhancing the capabilities of our military radio environment awareness, forecasting, warning and assessment of the effect is significant.In this paper, the original geographic data and radio wave propagation data will be unified as vector and raster data into GIS system structure based on ArcObjects components, combined with the development of visual language Visual C++ 6.0, designed and constructed to assess the effect of radio wave propagation simulation system. designed and built a radio wave propagation effects assessment simulation system. The system has data management, scene visualization, effects assessment, graphics output function modules, Achieved wave propagation effects assessment simulation and visualization presentation.

scholarly journals Virtual Reality Simulation and Augmented Reality-Guided Surgery for Total Maxillectomy: A Case Report

2020 ◽  
Vol 10 (18) ◽  
pp. 6288
Author(s):  
Hee-Jin Kim ◽  
Ye-Joon Jo ◽  
Jun-Seok Choi ◽  
Hyo-Joon Kim ◽  
In-Seok Park ◽  
...  
Keyword(s):  
Virtual Reality ◽  
Augmented Reality ◽  
Preoperative Planning ◽  
Fibrous Histiocytoma ◽  
Maxillofacial Surgery ◽  
Surgical Techniques ◽  
Virtual Reality Simulation ◽  
Guided Surgery ◽  
Total Maxillectomy ◽  
Orbital Floor Reconstruction

With the improvement in computer graphics and sensors, technologies like virtual reality (VR) and augmented reality (AR) have created new possibilities for developing diagnostic and surgical techniques in the field of surgery. VR and AR are the latest technological modalities that have been integrated into clinical practice and medical education, and are rapidly emerging as powerful tools in the field of maxillofacial surgery. In this report, we describe a case of total maxillectomy and orbital floor reconstruction in a patient with malignant fibrous histiocytoma of the maxilla, with preoperative planning via VR simulation and AR-guided surgery. Future developments in VR and AR technologies will increase their utility and effectiveness in the field of surgery.

scholarly journals Clinical efficacy and effectiveness of 3D printing: a systematic review

BMJ Open ◽  
2017 ◽  
Vol 7 (12) ◽  
pp. e016891 ◽  
Author(s):  
Laura E Diment ◽  
Mark S Thompson ◽  
Jeroen H M Bergmann
Keyword(s):  
Systematic Review ◽  
3D Printing ◽  
Clinical Efficacy ◽  
Musculoskeletal System ◽  
Preoperative Planning ◽  
Maxillofacial Surgery ◽  
Oral And Maxillofacial Surgery ◽  
Level Of Evidence ◽  
Standard Clinical Practice ◽  
3D Printed

ObjectiveTo evaluate the clinical efficacy and effectiveness of using 3D printing to develop medical devices across all medical fields.DesignSystematic review compliant with Preferred Reporting Items for Systematic Reviews and Meta-Analyses.Data sourcesPubMed, Web of Science, OVID, IEEE Xplore and Google Scholar.MethodsA double-blinded review method was used to select all abstracts up to January 2017 that reported on clinical trials of a three-dimensional (3D)-printed medical device. The studies were ranked according to their level of evidence, divided into medical fields based on the International Classification of Diseases chapter divisions and categorised into whether they were used for preoperative planning, aiding surgery or therapy. The Downs and Black Quality Index critical appraisal tool was used to assess the quality of reporting, external validity, risk of bias, risk of confounding and power of each study.ResultsOf the 3084 abstracts screened, 350 studies met the inclusion criteria. Oral and maxillofacial surgery contained 58.3% of studies, and 23.7% covered the musculoskeletal system. Only 21 studies were randomised controlled trials (RCTs), and all fitted within these two fields. The majority of RCTs were 3D-printed anatomical models for preoperative planning and guides for aiding surgery. The main benefits of these devices were decreased surgical operation times and increased surgical accuracy.ConclusionsAll medical fields that assessed 3D-printed devices concluded that they were clinically effective. The fields that most rigorously assessed 3D-printed devices were oral and maxillofacial surgery and the musculoskeletal system, both of which concluded that the 3D-printed devices outperformed their conventional comparators. However, the efficacy and effectiveness of 3D-printed devices remain undetermined for the majority of medical fields. 3D-printed devices can play an important role in healthcare, but more rigorous and long-term assessments are needed to determine if 3D-printed devices are clinically relevant before they become part of standard clinical practice.

scholarly journals The RNA Methyltransferase METTL3 Promotes Endothelial Progenitor Cell Angiogenesis in Mandibular Distraction Osteogenesis via the PI3K/AKT Pathway

2021 ◽  
Vol 9 ◽  
Author(s):  
Weidong Jiang ◽  
Peiqi Zhu ◽  
Fangfang Huang ◽  
Zhenchen Zhao ◽  
Tao Zhang ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Distraction Osteogenesis ◽  
Ex Vivo ◽  
Maxillofacial Surgery ◽  
Akt Pathway ◽  
Oral And Maxillofacial Surgery ◽  
Endothelial Progenitor ◽  
Mandibular Distraction Osteogenesis

Distraction osteogenesis (DO) is used to treat large bone defects in the field of oral and maxillofacial surgery. Successful DO-mediated bone regeneration is dependent upon angiogenesis, and endothelial progenitor cells (EPCs) are key mediators of angiogenic processes. The N6-methyladenosine (m6A) methyltransferase has been identified as an important regulator of diverse biological processes, but its role in EPC-mediated angiogenesis during DO remains to be clarified. In the present study, we found that the level of m6A modification was significantly elevated during the process of DO and that it was also increased in the context of EPC angiogenesis under hypoxic conditions, which was characterized by increased METTL3 levels. After knocking down METTL3 in EPCs, m6A RNA methylation, proliferation, tube formation, migration, and chicken embryo chorioallantoic membrane (CAM) angiogenic activity were inhibited, whereas the opposite was observed upon the overexpression of METTL3. Mechanistically, METTL3 silencing reduced the levels of VEGF and PI3Kp110 as well as the phosphorylation of AKT, whereas METTL3 overexpression reduced these levels. SC79-mediated AKT phosphorylation was also able to restore the angiogenic capabilities of METTL3-deficient EPCs in vitro and ex vivo. In vivo, METTL3-overexpressing EPCs were additionally transplanted into the DO callus, significantly enhancing bone regeneration as evidenced by improved radiological and histological manifestations in a canine mandibular DO model after consolidation over a 4-week period. Overall, these results indicate that METTL3 accelerates bone regeneration during DO by enhancing EPC angiogenesis via the PI3K/AKT pathway.

scholarly journals Study on the Effect of Bilateral Mandible Distraction Osteogenesis About the Nutrition Status of Infants With Pierre-Robin Sequence

2021 ◽  
Vol 9 ◽  
Author(s):  
Liu Jiayu ◽  
Sun Jing ◽  
Chen Yiyang ◽  
Li Fan
Keyword(s):  
Food Intake ◽  
Distraction Osteogenesis ◽  
Maxillofacial Surgery ◽  
Albumin Level ◽  
The Body ◽  
Nutrition Status ◽  
Pierre Robin Sequence ◽  
Robin Sequence ◽  
Blood Albumin ◽  
Pierre Robin

Objective: By comparing and studying the changes of food intake, weight, body length, BMI, blood albumin level and other indicators of infants with Pierre-Robin Sequence (PRS) before and after Bilateral Mandible Distraction Osteogenesis operation, to explore the effect of distraction osteogenesis on PRS patients about the improvement of nutrition status.Methods: The children with PRS who admitted to the Oral and Maxillofacial Surgery Department of Guangzhou Women and Children's Medical Center from July 2015 to December 2020 were selected. All patients accepted bilateral mandible distraction osteogenesis surgery, and the pre- and post-operative indicators were recorded, such as food intake, weight, length, blood albumin level and others. BMI was calculated based on the indicators mentioned above, and comparative statistical analysis was performed.Results: 1. All patients were fed with whole milk before the first surgery, and the average calorie per kg was 91.8 kcal/kg, significantly lower than the standard (100–150 kcal/kg), suggesting the overall nutritional intake of PRS patients is low; 2. t tests for independent samples were used to analyze the pre-operative and post-operative indicators. The WFA percentile increased from 14.16 ± 2.17 to 15.01 ± 1.85% (P = 0.0048), WFA z score increased from −2.40 ± 0.18 to −1.90 ± 0.14 after the surgery (P = 0.0010), LFA percentile increased from 20.04 ± 3.48 to 33.67 ± 4.29% (P = 0.0098), LFA z score increased from −2.09 ± 0.19 to −1.42 ± 0.23 (P = 0.0009), BMI z score increased from −1.95 ± 0.22 to −1.39 ± 0.16 (P = 0.0408), ALB raised from 37.06 ± 0.51 to 42.85 ± 0.30 g/L (P < 0.001), which indicating that the physique of patients improved after the distraction osteogenesis surgery, mainly was reflected by the lifting of weight and length growth curves; the body shape also improved, indicating that the patients' nutrition status after the surgery is also improved.Conclusion: Bilateral mandible distraction osteogenesis surgery has a positive effect on the nutrition status of children with PRS. This effect is mainly reflected by the improvements of the body physical indicators after surgery.

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