New Research on the Pharmaceutical Chemistry of Plant Polysaccharides

2013 ◽  
Vol 411-414 ◽  
pp. 3237-3241
Author(s):  
Qi Chang Dai ◽  
Cui Ting Chen ◽  
Miao Yu ◽  
Yu Bin Ji
Keyword(s):  
Medicinal Chemistry ◽  
Chemical Technology ◽  
Pharmaceutical Chemistry ◽  
Separation And Purification ◽  
Plant Polysaccharides ◽  
Advantages And Disadvantages ◽  
Extraction Separation ◽  
New Research

The researches on plant polysaccharides develop rapidly in recent years. In this paper, the studies of pharmaceutical chemistry of polysaccharides from plants are reviewed. We introduce researches’ new progresses and results of the extraction, separation and purification in the field of pharmaceutical chemistry and expound the advantages and disadvantages of the applications of physical techniques, chemical technology and biotechnology. The applications of statistic principles in the field of medicinal chemistry are also discussed in this article.

scholarly journals Technologies for the Extraction, Separation and Purification of polyphenols – A Review

2019 ◽  
Vol 6 (1) ◽  
pp. 74-91 ◽  
Author(s):  
Shyam Suwal ◽  
Alice Marciniak
Keyword(s):  
Organic Molecules ◽  
Extraction Efficiency ◽  
Positive Impact ◽  
Cost Effective ◽  
Separation And Purification ◽  
Advantages And Disadvantages ◽  
Assisted Extraction ◽  
Extraction Separation ◽  
Current Context ◽  
Conventional Extraction

Polyphenols are high molecular weight, organic molecules mainly found in plant kingdom. They are mostly known for their positive impact on health, specifically for their antioxidant activity. Indeed, they are widely studied for the prevention of multiple diseases such as cancer, inflammatory, cardiovascular and neurodegenerative diseases. Nevertheless, extractions of these growing interest molecules remain challenging using conventional methods such as solvent extraction. That is why recent researches have focused on improving the extraction of polyphenol by using different technologies such as ultrasound, microwave, pressurized liquid, pulsed electric field, supercritical fluid and high hydrostatic pressure. In the current context, the assisted-extraction should demonstrate their potential to improve the extraction efficiency while being cost-effective and with a low environmental impact. To this end, technologies ought to, for instance, increase the solubility of polyphenol and the permeability of the cell wall. Consequently, this review is focused on the use and potential of these technologies to improve polyphenol extractions from plants as well as their purification using various methods. It discusses of the advantages and disadvantages with some examples of all these technologies assisted-extraction in comparison with conventional extraction method as well as purification technology.

Beyond DNA-targeting in Cancer Chemotherapy. Emerging Frontiers- A Review

2020 ◽  
Vol 20 ◽  
Author(s):  
S.N Mbugua ◽  
L.W Njenga ◽  
R.A Odhiambo ◽  
S.O Wandiga ◽  
M.O Onani
Keyword(s):  
Superparamagnetic Iron Oxide ◽  
Active Centre ◽  
Dna Targeting ◽  
Advantages And Disadvantages ◽  
Cancer Pathogenesis ◽  
Ongoing Work ◽  
Target Dna ◽  
Anti Cancer ◽  
New Research ◽  
Innovative Drugs

: Modern anticancer drugs target DNA specifically on rapid division of malignant cells. One downside of this approach is that they also target other rapidly dividing healthy cells such as those involved in hair growth leading to serious toxic side effects and hair loss. Therefore, it would be better to develop novel agents that address cellular signalling mechanisms unique to cancerous cells, and new research is now focussing on such approaches. Although the classical chemotherapy area involving DNA as the set target continues to produce important findings, nevertheless, a distinctly discernible emerging trend is the divergence from the cisplatin operation model that uses the metal as the primary active centre of the drug. Many successful anti-cancer drugs present are associated with elevated toxicity levels. Cancers also develop immunity against most therapies and the area of cancer research can therefore be seen as an area with a high unaddressed need. Hence, ongoing work into cancer pathogenesis is important to create accurate preclinical tests which can contribute to the development of innovative drugs to manage and treat cancer. Some of the emergent frontiers utilizing different approaches include nanoparticles delivery, use of quantum dots, metal complexes, tumour ablation, magnetic hypothermia and hyperthermia by use of Superparamagnetic Iron oxide Nanostructures, pathomics and radiomics, laser surgery and exosomes. This review summarizes these new approaches in good detail giving critical views with necessary comparisons. It also delves into what they carry for the future including their advantages and disadvantages.

scholarly journals Swarm Robotic Interactions in an Open and Cluttered Environment: A Survey

Designs ◽  
2021 ◽  
Vol 5 (2) ◽  
pp. 37
Author(s):  
Maxime Vaidis ◽  
Martin J.-D. Otis
Keyword(s):  
Literature Review ◽  
Research Trends ◽  
Cluttered Environment ◽  
Advantages And Disadvantages ◽  
Population Migrations ◽  
New Research ◽  
Interaction Strategy ◽  
Crowded Environment

Recent population migrations have led to numerous accidents and deaths. Little research has been done to help migrants in their journey. For this reason, a literature review of the latest research conducted in previous years is required to identify new research trends in human-swarm interaction. This article presents a review of techniques that can be used in a robots swarm to find, locate, protect and help migrants in hazardous environment such as militarized zone. The paper presents a swarm interaction taxonomy including a detailed study on the control of swarm with and without interaction. As the interaction mainly occurs in cluttered or crowded environment (with obstacles) the paper discussed the algorithms related to navigation that can be included with an interaction strategy. It focused on comparing algorithms and their advantages and disadvantages.

Frontiers in Medicinal Chemistry 2015: Meet the Experts of MedChem near the Cradle of Medicinal and Pharmaceutical Chemistry

ChemMedChem ◽  
2015 ◽  
Vol 10 (7) ◽  
pp. 1267-1271
Author(s):  
Christof Wegscheid-Gerlach ◽  
Hans-Dieter Gerber ◽  
Wibke E. Diederich
Keyword(s):  
Medicinal Chemistry ◽  
Pharmaceutical Chemistry

scholarly journals Liquid Biphasic System: A Recent Bioseparation Technology

Processes ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 149 ◽  
Author(s):  
Kuan Shiong Khoo ◽  
Hui Yi Leong ◽  
Kit Wayne Chew ◽  
Jun-Wei Lim ◽  
Tau Chuan Ling ◽  
...  
Keyword(s):  
Future Development ◽  
Future Prospect ◽  
Fundamental Principle ◽  
Present Review ◽  
Biphasic System ◽  
Separation And Purification ◽  
Separation Techniques ◽  
System A ◽  
Extraction Separation ◽  
Further Development

A well-known bioseparation technique namely liquid biphasic system (LBS) has attracted many researchers’ interest for being an alternative bioseparation technology for various kinds of biomolecules. The present review begins with an in-depth discussion on the fundamental principle of LBS and this is followed by the discussion on further development of various phase-forming components in LBS. Additionally, the implementation of various advance technologies to the LBS that is beneficial towards the efficiency of LBS for the extraction, separation, and purification of biomolecules was discussed. The key parameters affecting the LBS were presented and evaluated. Moreover, future prospect and challenges were highlighted to be a useful guide for future development of LBS. The efforts presented in this review will provide an insight for future researches in liquid-liquid separation techniques.

Studying the process of information selection in manuals

1999 ◽  
Vol 1 (2) ◽  
pp. 119-130 ◽  
Author(s):  
Nicole Ummelen
Keyword(s):  
Time Data ◽  
Thinking Aloud ◽  
Information Selection ◽  
Advantages And Disadvantages ◽  
Sentence Reading ◽  
Selection Processes ◽  
Data Collection And Analysis ◽  
Research Questions ◽  
New Research ◽  
Further Development

Research instruments for studying information selection in manuals should meet several goals at the same time. First of all, they should accurately register relevant data, such as selected information, selection moments, and reading times. They should also enable the reader to use both the manual and the accompanying product in a natural way. And finally, both data collection and analysis should not be too time-consuming or expensive. In this paper, four research instruments that may be used for studying selection processes in manuals are described and evaluated with respect to these three requirements. Three of them are well-known from other research domains: recording sentence reading times by button presses, methods of eye movement registration and the thinking aloud technique. The fourth, called the click & read method, was recently developed for studying the use of procedural and declarative information in software manuals. This instrument presents the manual in a paper layout on a large screen. The text is presented in blocks of comparable length and is initially blurred. Non-blurred headings above the blocks enable readers to select a block and sharpen it by clicking on it. These clicks are recorded and thus provide selection and time data. The evaluation shows that none of the four instruments is suitable for all research questions about manual use: instruments should be carefully chosen for specific research questions. Then again, all techniques have their advantages and disadvantages, some of which we are not yet certain about. Therefore, the paper concludes by arguing that a thorough analysis, comparison and further development of available and new research instruments is necessary to further facilitate and improve studies of information selection and processing

scholarly journals II International Symposium of Medicinal Chemistry and Regenerative Medicine

2018 ◽  
Vol 1 (1) ◽  
pp. 48
Author(s):  
Several Authors
Keyword(s):  
Graduate Students ◽  
Regenerative Medicine ◽  
International Symposium ◽  
Medicinal Chemistry ◽  
Innovation Management ◽  
Scientific Session ◽  
Scientific Committee ◽  
Research Projects ◽  
New Research ◽  
Pharmaceutical Biotechnology

The II International Symposium on Medicinal Chemistry and Regenerative Medicine, held from November 22nd to 24th at, this event was directed to undergraduate and graduate students, professionals from the medical, pharmaceutical, biotechnology innovation management and entrepreneurs, as well as researchers involved in the areas of Medicinal Chemistry, Regenerative Medicine and Biotechnology.The event aimed to promote the dissemination of new research and innovations that are at the frontier of knowledge in the area of Regenerative Medicine and Medicinal Chemistry and also to promote interaction with companies interested in these researches. Thus, as a result of the event, it is hoped to encourage discussion, sharing of knowledge, articulation of partnerships for new research projects and also generate a spark of ideas that can be led by future entrepreneurs.In this second edition, a scientific session was held with the presentation of posters. The abstracts submitted and approved by the scientific committee are below.Central themes● Biopolymers● Medicinal Chemistry● Regenerative Medicine● Innovation Management on Biotechnology

scholarly journals Recent Advances of the Constitutive Models of Smart Materials — Hydrogels and Shape Memory Polymers

2020 ◽  
Vol 12 (02) ◽  
pp. 2050014 ◽  
Author(s):  
Rong Huang ◽  
Shoujing Zheng ◽  
Zishun Liu ◽  
Teng Yong Ng
Keyword(s):  
Phase Transition ◽  
Shape Memory ◽  
Smart Materials ◽  
Constitutive Models ◽  
Shape Memory Polymers ◽  
Soft Materials ◽  
Advantages And Disadvantages ◽  
Recent Advances ◽  
The One ◽  
New Research

Hydrogels and shape memory polymers (SMPs) possess excellent and interesting properties that may be harnessed for future applications. However, this is not achievable if their mechanical behaviors are not well understood. This paper aims to discuss recent advances of the constitutive models of hydrogels and SMPs, in particular the theories associated with their deformations. On the one hand, constitutive models of six main types of hydrogels are introduced, the categorization of which is defined by the type of stimulus. On the other hand, constitutive models of thermal-induced SMPs are discussed and classified into three main categories, namely, rheological models; phase transition models; and models combining viscoelasticity and phase transition, respectively. Another feature in this paper is a summary of the common hyperelastic models, which can be potentially developed into the constitutive models of hydrogels and SMPs. In addition, the main advantages and disadvantages of these constitutive modes are discussed. In order to provide a compass for researchers involved in the study of mechanics of soft materials, some research gaps and new research directions for hydrogels and SMPs constitutive modes are presented. We hope that this paper can serve as a reference for future hydrogel and SMP studies.

Sign in / Sign up

Export Citation Format

Share Document