A Three-Dimensional Porous Scaffold of Biodegradable Synthetic Polymers and Porous Hydroxyapatite Beads for Bone Tissue Engineering

2000 ◽  
Vol 192-195 ◽  
pp. 733-736 ◽  
Author(s):  
Takashi Ushida ◽  
Tamotsu Tamaki ◽  
Guo Ping Chen ◽  
Yoshikazu Umezu ◽  
Tetsuya Tateishi
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Porous Scaffold ◽  
Three Dimensional ◽  
Synthetic Polymers ◽  
Porous Hydroxyapatite

Fabrication of a chitosan/bioglass three-dimensional porous scaffold for bone tissue engineering applications

2014 ◽  
Vol 2 (38) ◽  
pp. 6611-6618 ◽  
Author(s):  
Jun Yang ◽  
Teng Long ◽  
Nan-Fei He ◽  
Ya-Ping Guo ◽  
Zhen-An Zhu ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Porous Scaffold ◽  
Three Dimensional ◽  
Bone Defects ◽  
Engineering Applications

A chitosan/bioglass three-dimensional porous scaffold with excellent biocompatibility and mechanical properties has been developed for the treatment of bone defects.

Bioinspired nanostructured hydroxyapatite/collagen three-dimensional porous scaffolds for bone tissue engineering

RSC Advances ◽  
2015 ◽  
Vol 5 (46) ◽  
pp. 36175-36184 ◽  
Author(s):  
Junjie Guan ◽  
Jun Yang ◽  
Junqi Dai ◽  
Yunhao Qin ◽  
Yang Wang ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Porous Scaffold ◽  
Three Dimensional ◽  
Porous Scaffolds ◽  
Needle Punching

A needle punching and bioinspired mineralization strategy has been developed to fabricate a collagen/hydroxyapatite porous scaffold for bone tissue engineering.

One pot method to synthesize three-dimensional porous hydroxyapatite nanocomposite for bone tissue engineering

2019 ◽  
Vol 27 (1) ◽  
pp. 225-235 ◽  
Author(s):  
Chandrani Sarkar ◽  
Kumar Anuvrat ◽  
Subhadra Garai ◽  
Sumanta Kumar Sahu ◽  
Jui Chakraborty
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Three Dimensional ◽  
One Pot ◽  
Porous Hydroxyapatite

Preparation of Nano-Hydroxyapatite/Polyamide6 Composite Porous Scaffold for Bone Tissue Engineering

2007 ◽  
Vol 544-545 ◽  
pp. 793-796
Author(s):  
Lin Cheng ◽  
Yu Bao Li ◽  
Yi Zuo ◽  
Gang Zhou ◽  
Hua Nan Wang ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Phase Separation ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Bone Growth ◽  
Porous Scaffold ◽  
Three Dimensional ◽  
Bone Tissue Regeneration ◽  
Structural Support ◽  
Human Cancellous Bone

Scaffold in bone tissue engineering must have a three-dimensional (3-D) interconnected porous structure acting as a template for bone tissue regeneration, and material fabricating the scaffold must be biocompatible and can provide structural support during bone growth and remodeling at the same time. In this paper, a method of phase separation and particle leaching combined (PS/PL) was used to prepare porous scaffold of nano-hydroxyapatite and polyamide6 (n-HA/PA6) composite. The results show that the scaffold prepared by PS/PL has not only interconnected macropores of 100~300 μm, but also micropores on the walls of macropores, and PS/PL scaffold is more interconnective in compare with phase separation (PS) scaffold. When the porosity of the scaffold is about 79%, its compressive strongth is about 3.27 MPa, that is similar to the human cancellous bone(2~10MPa). Ethanol has some effect on hydrogen bonds, but fabricating method will not change the chemical component of the composite. The porous scaffold is prospect for bone tissue engineering.

HYDROXYAPATITE, ALGINATE, AND CHITOSAN FOR BONE SCAFFOLDS: SPECTROSCOPY STUDY

2016 ◽  
Vol 19 (2) ◽  
pp. 93-100
Author(s):  
Lalita El Milla
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Functional Groups ◽  
Bone Growth ◽  
Three Dimensional ◽  
Dimensional Structure ◽  
Tissue Engineering Scaffolds ◽  
Hydroxyapatite Powder ◽  
Materials Used

Scaffolds is three dimensional structure that serves as a framework for bone growth. Natural materials are often used in synthesis of bone tissue engineering scaffolds with respect to compliance with the content of the human body. Among the materials used to make scafffold was hydroxyapatite, alginate and chitosan. Hydroxyapatite powder obtained by mixing phosphoric acid and calcium hydroxide, alginate powders extracted from brown algae and chitosan powder acetylated from crab. The purpose of this study was to examine the functional groups of hydroxyapatite, alginate and chitosan. The method used in this study was laboratory experimental using Fourier Transform Infrared (FTIR) spectroscopy for hydroxyapatite, alginate and chitosan powders. The results indicated the presence of functional groups PO43-, O-H and CO32- in hydroxyapatite. In alginate there were O-H, C=O, COOH and C-O-C functional groups, whereas in chitosan there were O-H, N-H, C=O, C-N, and C-O-C. It was concluded that the third material containing functional groups as found in humans that correspond to the scaffolds material in bone tissue engineering.

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