Two-Dimensional Cell Trapping Using Single Axicon Fiber without Physical Contact

2012 ◽  
Vol 523-524 ◽  
pp. 1070-1075 ◽  
Author(s):  
Kozo Taguchi

Chemically etched axicon fiber was proposed for two-dimensional cell trapping. We fabricated axicon micro lenses on a single-mode bare optical fiber by selective chemical etching technique. The laser beam from fiber axicon microlens was strongly focused and optical forces were sufficient to move a microorganisms and biological cells without physical contact. The apex angle of the chemically etched fiber axicon microlens was very important parameter for laser trapping. From these experimental results, it was found that our proposed method was a promising tool for the isolation of microorganisms.

2012 ◽  
Vol 516 ◽  
pp. 580-584 ◽  
Author(s):  
Kozo Taguchi ◽  
Shinya Imanaka

In this paper, chemically etched axicon fibre was proposed for laser trapping of micro-objects dispersed in liquid. We fabricated axicon microlenses on a single-mode bare optical fibre using a selective chemical etching technique. The laser beam from a fibre axicon microlens was strongly focused and optical forces were sufficient to move microorganisms and biological cells without physical contact. From the experimental results, it was found that our proposed fibre axicon microlens is a promising tool for cell trapping and the apex angle of the chemically etched fibre axicon microlens is a very important parameter for laser trapping.


2014 ◽  
Vol 625 ◽  
pp. 695-699
Author(s):  
Kozo Taguchi ◽  
Takuya Hayashi

In this paper, chemically etched axicon fiber was investigated for laser trapping of micro-object dispersed in liquid. We fabricated axicon micro lenses on a single-mode bare optical fiber by selective chemical etching technique. The laser beam from fiber axicon microlens was strongly focused and optical forces were sufficient to move a microorganisms and biological cells without physical contact. In our experiments, several different lasers with various wavelengths were used as light sources. From these experimental results, it was found that laser wavelength was very important parameter for cell trapping and laser wavelength should be selected to avoid absorption by cells in order to prevent thermal degradation and damage to the cells.


Sensors ◽  
2018 ◽  
Vol 18 (9) ◽  
pp. 2746 ◽  
Author(s):  
Sandra Rodrigues ◽  
Joana Paiva ◽  
Rita Ribeiro ◽  
Olivier Soppera ◽  
João Cunha ◽  
...  

Optical fiber tweezers have been gaining prominence in several applications in Biology and Medicine. Due to their outstanding focusing abilities, they are able to trap and manipulate microparticles, including cells, needing any physical contact and with a low degree of invasiveness to the trapped cell. Recently, we proposed a fiber tweezer configuration based on a polymeric micro-lens on the top of a single mode fiber, obtained by a self-guided photopolymerization process. This configuration is able to both trap and identify the target through the analysis of short-term portions of the back-scattered signal. In this paper, we propose a variant of this fabrication method, capable of producing more robust fiber tips, which produce stronger trapping effects on targets by as much as two to ten fold. These novel lenses maintain the capability of distinguish the different classes of trapped particles based on the back-scattered signal. This novel fabrication method consists in the introduction of a multi mode fiber section on the tip of a single mode (SM) fiber. A detailed description of how relevant fabrication parameters such as the length of the multi mode section and the photopolymerization laser power can be tuned for different purposes (e.g., microparticles trapping only, simultaneous trapping and sensing) is also provided, based on both experimental and theoretical evidences.


1997 ◽  
Vol 82 (11) ◽  
pp. 5811-5815 ◽  
Author(s):  
Suneeta S. Neogi ◽  
David Venables ◽  
Zhiyong Ma ◽  
Dennis M. Maher ◽  
Mitchell Taylor ◽  
...  

Author(s):  
Jungwoo Lee ◽  
Changyang Lee ◽  
Hyung Ham Kim ◽  
Anette Jakob ◽  
Robert Lemor ◽  
...  

2002 ◽  
Vol 16 (08) ◽  
pp. 1217-1223 ◽  
Author(s):  
K. V. MCCLOUD ◽  
M. L. KURNAZ

The roughness exponent of surfaces obtained by dispersing silica spheres into a quasi-two-dimensional cell is examined. The cell consists of two glass plates separated by a gap, which is comparable in size to the diameter of the beads. Previous work has shown that the quasi-one-dimensional surfaces formed have two roughness exponents in two length scales, which have a crossover length about 1 cm. We have studied the effect of changing the gap between the plates to a limit of about twice the diameter of the beads. If the conventional scaling analysis is performed, the roughness exponent is found to be robust against changes in the gap between the plates; however, the possibility that scaling does not hold should be taken seriously.


2009 ◽  
Vol 16 (5) ◽  
pp. 540-547 ◽  
Author(s):  
Takehiro Fukushima ◽  
Yoshiyuki Handa ◽  
Kunihiro Miyahara

2009 ◽  
Author(s):  
Iraís Solís ◽  
M. Torres-Cisneros ◽  
J. G. Aviña-Cervantes ◽  
O. G. Ibarra-Manzano ◽  
O. Debeir ◽  
...  

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