Modelling of a Piezoelectric Polymer Film System for Biosensing Applications

2010 ◽  
Vol 636-637 ◽  
pp. 1206-1211
Author(s):  
Paulo Inácio ◽  
J.N. Marat-Mendes ◽  
Eugen R. Neagu ◽  
C.J. Dias

Most piezoelectric gravimetric biosensors are based on quartz crystal microbalances or surface acoustic wave devices. In this paper we describe a polymer film system, made of piezoelectric polyvinylidene difluoride (PVDF) and the Immobilon-P membrane (porous PVDF), for biosensing applications. In operation a film is accommodated in a flow cell and connected to an electronic circuit, constituting an oscillatory resonant device; the output signal is its resonance frequency. This device successfully detected the binding between bovine IgG and bovine anti-IgG. Work on the modelling of this film system is presented. Two different approaches are being considered: the finite element method (FEM) and the ABCD matrices. Results comparing theoretical and experimental data are presented.

2006 ◽  
Vol 514-516 ◽  
pp. 910-914
Author(s):  
Paulo Inácio ◽  
José N. Marat-Mendes ◽  
C.J. Dias

Most piezoelectric biosensors normally use crystals, as in the quartz crystal microbalances or surface acoustic wave devices. A new system is described in which piezoelectric polymer films (made of polyvinylidene fluoride, PVDF, and Immobilon, a porous type of PVDF) are used to produce a mass sensitive oscillatory resonant device. Recent results demonstrated that this system successfully detects the binding between bovine IgG (immunoglobulin G) and anti bovine IgG. In order to improve the performance of the biosensor the electromechanical behaviour of such film-membrane is being studied. Miniaturization is also a desirable trend which will be pursued. Thus reports on the dependence on the electrical, mechanical and biological properties with the size of the film will be presented.


2020 ◽  
Vol 3 (6) ◽  
pp. 5687-5697 ◽  
Author(s):  
Roto Roto ◽  
Aditya Rianjanu ◽  
Annisa Rahmawati ◽  
Innas Amaliya Fatyadi ◽  
Nursidik Yulianto ◽  
...  

1993 ◽  
Vol 32 (Part 1, No. 5B) ◽  
pp. 2288-2290 ◽  
Author(s):  
Yasuhiro Nakamura ◽  
Takeshi Kawabata ◽  
Takahiko Otani

Author(s):  
Diego Scaccabarozzi ◽  
Bortolino Saggin ◽  
Marianna Magni ◽  
Pietro Valnegri ◽  
Marco Giovanni Corti ◽  
...  

1993 ◽  
pp. 371-378
Author(s):  
G. R. Li ◽  
K. Omote ◽  
K. S. Park ◽  
S. Takahashi ◽  
H. Ohigashi ◽  
...  

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