Factors associated with cognitive recovery after cardiopulmonary resuscitation

1996 ◽  
Vol 5 (2) ◽  
pp. 127-139 ◽  
Author(s):  
MJ Sauve ◽  
N Doolittle ◽  
JA Walker ◽  
SM Paul ◽  
MM Scheinman

BACKGROUND: A range of neuro-cognitive sequelae, from mild intellectual impairments to brain death, have been reported in survivors of aborted sudden cardiac death. PURPOSE: To determine to what extent, if any, factors associated with cardiopulmonary resuscitation, left ventricular function, and mood state are related to outcomes in five cognitive areas, namely orientation, attention, memory, reasoning, and motor performance. METHODS: Repeated measures were used to assess cognitive outcomes in 45 sudden cardiac arrest survivors over the 6 months following cardiopulmonary resuscitation. A battery of neuro-psychological tests was used to assess cognitive outcomes and psychological status over time. The relationship of the cardiopulmonary resuscitation, left ventricular function, and psychological variables to cognitive outcomes were assessed at each data point. The independent variables included time to cardiopulmonary resuscitation, time to defibrillation, duration of cardiopulmonary resuscitation, time to awakening, ejection fraction, New York Heart Association Class I to IV, tension, anger, and depression. RESULTS: During hospitalization 38 of the 45 survivors (84%) had mild to severe deficits in one or more cognitive areas; 19 of 38 survivors (50%) continued to be impaired in one or more cognitive areas at 6 months. Of these, all had mild to severe deficits in at least one aspect of memory, with delayed recall the most frequent impairment. Time to awakening accounted for a unique portion of the variance in orientation and memory outcomes over time. The left ventricular function variables accounted for a significant portion of the variance in motor speed. CONCLUSIONS: Our results suggest that half of the long-term survivors of aborted sudden cardiac death are cognitively intact 6 months after resuscitation but that 25% have moderate to severe impairment in memory, which could hamper and/or preclude the resumption of prearrest roles.

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Henrike Andresen ◽  
B. Sasko ◽  
D. Patschan ◽  
N. Pagonas ◽  
O. Ritter

Abstract Background The implantation of cardioverter defibrillators (ICDs) is an established therapy in the prevention of sudden cardiac death in patients with systolic dysfunction after myocardial infarction. To avoid immediate implantation of an ICD, wearable cardioverter defibrillator vests (WCD) can be used to protect patients against malignant rhythm disorders, while at the same time drug-based heart failure therapy has to be initiated. This drug therapy can improve left ventricular ejection fraction and primary prophylactic cardioverter defibrillator implantation may not be necessary. However, the recent Vest Prevention of Early Sudden Death Trial (VEST) questioned the regular use of the WCD in this setting. Case presentation A 47-year-old Caucasian man with severely impaired left ventricular function early after myocardial infarction was prescribed a WCD as primary prophylaxis to prevent sudden cardiac death. Seven days after the patient was supplied with a WCD, the patient suffered from an electrical storm with recurrent ventricular tachycardia (VT), which was successfully terminated 17 times by the WCD. On coronary angiography, the formerly infarct-related right coronary artery had TIMI (Thrombolysis in Myocardial Ischemia Trial) III flow, and a remaining stenosis in the left anterior descending artery (LAD) was stented, which did not stop recurrent VT. In the electrophysiology (EP) study, a focus was mapped in the left inferior ventricle, which was ablated. This stopped the VT. A second radio-frequency (RF) ablation in the same area was necessary after 14 days. Finally, a permanent cardioverter defibrillator was implanted. Conclusion We report the case of a patient who survived recurrent episodes of VT early after myocardial infarction by effective defibrillation with a WCD. The WCD is a useful device to bridge time until a final decision for implantation of a defibrillator.


Heart Rhythm ◽  
2005 ◽  
Vol 2 (5) ◽  
pp. S33 ◽  
Author(s):  
Amy J. Mangrum ◽  
David Lin ◽  
John P. Dimarco ◽  
W. Kline Bolton ◽  
J. Michael Mangrum

2005 ◽  
Vol 0 (0) ◽  
pp. 051123074027004-??? ◽  
Author(s):  
EDUARDO BACK STERNICK ◽  
MARTINO MARTINELLI ◽  
ROGERIO CORREIA SAMPAIO ◽  
LUIZ MARCIO GERKEN ◽  
RICARDO ALKMIM TEIXEIRA ◽  
...  

PLoS ONE ◽  
2018 ◽  
Vol 13 (9) ◽  
pp. e0203363 ◽  
Author(s):  
E. Samuli Lepojärvi ◽  
Heikki V. Huikuri ◽  
Olli-Pekka Piira ◽  
Antti M. Kiviniemi ◽  
Johanna A. Miettinen ◽  
...  

1996 ◽  
Vol 32 (1) ◽  
pp. 57-62 ◽  
Author(s):  
CA Calvert ◽  
GJ Jacobs ◽  
CW Pickus

Exacerbation of heart rhythm disturbances or deterioration of left-ventricular function occurred in six Doberman pinschers with occult cardiomyopathy following anesthesia and surgery. These abnormalities improved over time in surviving dogs, supporting a causal relationship between anesthesia/surgery and exacerbation. Moderate myocardial failure and ventricular tachyarrhythmias of variable severity existed prior to anesthesia and surgery in each dog. The incidence of these adverse effects is uncertain but probably significant. Exacerbation of arrhythmias may be life-threatening or lethal. Embarrassment of left-ventricular function may be inapparent or, if function already is marginal, may precipitate congestive heart failure.


Sign in / Sign up

Export Citation Format

Share Document