scholarly journals Nutritional composition of Jatropha tanjorensis leaves and effects of its aqueous extract on carbon tetrachloride induced oxidative stress in male Wistar albino rats

2018 ◽  
Vol 29 (19) ◽  
Author(s):  
Ochulor Okechukwu Chigozie ◽  
Njoku Obioma Uzoma ◽  
Uroko Robert Ikechukwu ◽  
Egba Simeon Ikechukwu
Keyword(s):  
Oxidative Stress ◽  
Carbon Tetrachloride ◽  
Aqueous Extract ◽  
Nutritional Composition ◽  
Albino Rats ◽  
Wistar Albino Rats

scholarly journals Hepatoprotective effects of Tagetes lucida root extract in carbon tetrachloride-induced hepatotoxicity in Wistar albino rats through amelioration of oxidative stress

2021 ◽  
Vol 59 (1) ◽  
pp. 986-997
Author(s):  
Samah Ali El-Newary ◽  
Rasha Fouad Ismail ◽  
Nermeen Mohammed Shaffie ◽  
Saber Fayez Hendawy ◽  
Elsayed Omer ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Carbon Tetrachloride ◽  
Albino Rats ◽  
Root Extract ◽  
Hepatoprotective Effects ◽  
Wistar Albino Rats

Effects of erdosteine on cyclosporin-A-induced nephrotoxicity

2011 ◽  
Vol 31 (6) ◽  
pp. 565-573 ◽  
Author(s):  
M Tutanc ◽  
V Arica ◽  
N Yılmaz ◽  
A Nacar ◽  
I Zararsiz ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cyclosporin A ◽  
Protective Role ◽  
Control Group ◽  
Albino Rats ◽  
Protective Mechanism ◽  
Antioxidant Parameters ◽  
Group 2 ◽  
Wistar Albino Rats

Aim: In cyclosporin-A (CsA)-induced toxicity, oxidative stress has been implicated as a potential responsible mechanism. Therefore, we aimed to investigate the protective role of erdosteine against CsA-induced nephrotoxicity in terms of tissue oxidant/antioxidant parameters and light microscopy in rats. Materials and methods: Wistar albino rats were randomly separated into four groups. Group 1 rats treated with sodium chloride served as the control, group 2 rats were treated with CsA, group 3 with CsA plus erdosteine, and group 4 with erdosteine alone. Animals were killed and blood samples were analyzed for blood urea nitrogen (BUN), serum creatinine (Cr), uric acid (UA), total protein (TP), and albumin (ALB) levels. Kidney sections were analyzed for malondialdehyde (MDA) and nitric oxide (NO) levels and superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities, as well as for histopathological changes. Results: In the CsA group, MDA, GSH-Px, BUN, and Cr levels were increased. The TP and ALB levels were decreased. These changes had been improved by erdosteine administration. Other biochemical parameters did not show any significant change. Conclusion: These results indicate that erdosteine produces a protective mechanism against CsA-induced nephrotoxicity and suggest a role of oxidative stress in pathogenesis.

Role of Diosmin in protection against the oxidative stress induced damage by gamma-radiation in Wistar albino rats

2020 ◽  
Vol 113 ◽  
pp. 104622 ◽  
Author(s):  
Shahenda Mahgoub ◽  
Anas O. Sallam ◽  
Hazem K.A. Sarhan ◽  
Amal A.A. Ammar ◽  
Sameh H. Soror
Keyword(s):  
Oxidative Stress ◽  
Gamma Radiation ◽  
Albino Rats ◽  
Wistar Albino Rats

Antioxidant properties of ethanol and fractions of ocimum gratissimum leave in paracetamol-induced oxidative stress in Wistar albino rats.

2016 ◽  
Vol 6 (2) ◽  
pp. 66
Author(s):  
ukpabiugo ukpabiugo ◽  
Jacinta Chigozie ◽  
Patrick Iwuanyanwu ◽  
kingsley Chukwuemeka ◽  
Monanu Okechukwu
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Properties ◽  
Albino Rats ◽  
Ocimum Gratissimum ◽  
Wistar Albino Rats
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