Erectile function after repeat saturation prostate biopsy: Our experience in 100 patients

Introduction: Erectile dysfunction (ED) incidence following repeat saturation prostate biopsy (SPBx) was evaluated. Materials and methods: From January 2011 to June 2012 295 patients underwent repeat transperineal SPBx (median 28 cores) under sedation. The indications for biopsy were: abnormal DRE, PSA > 10 ng/mL or included between 4.1-10 with free/total PSA < 25%. All patients were prospectively evaluated with the 5-item version of the International Index of Erectile Function (IIEF-5) at baseline and 1, 3 and 6 months from SPBx. Results: 100/200 men with benign histology and normal sexual activity completed the study; median IIEF-5 score before and after SPBx was equal to 18.3 (baseline) vs 17.8 (1 month later) vs 18 (3 months later) vs 18.1 (6 months later) (p > 0.05); in detail, 1 month from biopsy 5 (5%) men referred a mild ED that disappeared at 3 and 6 months evaluation. Conclusions: Repeat transperineal SPBx under sedation did not significantly worsened erectile function; the minimal risk of temporary post-biopsy ED could be previously discussed (not emphasised) with potent patients.

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CHANGES IN ERECTILE FUNCTION BEFORE AND AFTER PROSTATE BIOPSY

Indonesian Journal of Urology ◽

10.32421/juri.v20i2.9 ◽

2013 ◽

Vol 20 (2) ◽

Author(s):

Wibisono Wibisono ◽

Doddy Musbadianto Soebadi ◽

Sabilal Alif ◽

Widodo Pudjirahardjo

Keyword(s):

Erectile Dysfunction ◽

Rectal Bleeding ◽

Prostate Biopsy ◽

Erectile Function ◽

Transrectal Ultrasound ◽

Minimal Invasive ◽

Pathological Examination ◽

Before And After ◽

Function Assessment

Objective: To evaluate erectile function before and after transrectal ultrasound (TRUS) guided prostate biopsy using International Index of Erectile Function-5 (IIEF-5) and Erection Hardness Score (EHS) instrument. Material & Method: We conducted a study on 17 BPH LUTS patients who underwent TRUS guided prostate biopsy from January to April 2011 in Urological Minimal Invasive Installation (IIU) Dr. Soetomo Hospital. Out of 17 patients, three patients had mild ED, while 14 other patients had normal erectile function before the procedure. After TRUS guided prostate biopsy, we performed erectile function assessment using the IIEF-5 and EHS at weeks I, II, and IV. Results: Pathological examination of all specimens from prostate biopsy results revealed BPH. There were 2 patients with hematuria and 1 patient with rectal bleeding shortly after the biopsy, which resolved spontaneously less than 24 hours. Based on the IIEF-5 there were 4 patients (23,5%) with decreased erectile function in the evaluation of first week after prostate biopsy, and it reduced to 2 patients (11,7%) whose erectile function was still decreasing in the evaluation week II, while in fourth week evaluation there was 1 patient (5,9%) with decreased erectile function. Based on EHS data obtained, there were 5 patients (29,4%) with decreased scores in evaluations week II, and in the evaluation of week IV there were no patients having erectile function problems compared with EHS data before prostate biopsy. Conclusion: TRUS guided prostate biopsy can have temporary effect on erectile function.Keywords: Erectile dysfunction, prostate biopsy, international index of erectile function-5, erection hardness score.

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When should the evaluation of erectile function be done before radical prostatectomy?

Urologia Journal ◽

10.1177/0391560319842956 ◽

2019 ◽

Vol 86 (3) ◽

pp. 148-151

Author(s):

Ali Yıldız ◽

Kaan Karamık ◽

Yasin Aktaş ◽

Hakan Anıl ◽

Ekrem İslamoğlu ◽

...

Keyword(s):

Erectile Dysfunction ◽

Surgical Treatment ◽

Radical Prostatectomy ◽

Prostate Biopsy ◽

Erectile Function ◽

Transrectal Ultrasound ◽

Before And After

The aim of this study is to assess the erectile function of patients before and after transrectal ultrasound prostate biopsy comparatively in order to determine the appropriate time to evaluate erectile function before radical prostatectomy. A total of 44 patients underwent transrectal ultrasound biopsy. We used the International Index of Erectile Function-5 questionnaire to assess all the patients. In total, 44 volunteered patients were included in this study. All patients were evaluated with the International Index of Erectile Function-5 questionnaire before the biopsy and at 4 weeks after the transrectal ultrasound biopsy. A total of 50% of patients were potent before the biopsy was done. A month after the biopsies, erectile dysfunction was reported by 29 of 44 patients (66%) as mild in 10 (22.7%), as mild-moderate in 14 (31.8%), as moderate in 4 (9.1%), and severe in 1 (2.3%). The differences were statistically significant in the first month of the biopsy ( p < 0.05). The effect of prostate biopsy upon the erectile function is non-negligible. However, this situation is temporary and transient. Therefore, it is recommended that the International Index of Erectile Function-5 questionnaire is to be administered prior to prostate biopsy rather than before surgical treatment.

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The Comparison of Penile Doppler Ultrasonography Findings with Serum Lipid Parameters in Hyperlipidemic Patients with Erectile Dysfunction

Grand Journal of Urology ◽

10.5222/gju.2021.65376 ◽

2021 ◽

Author(s):

Mustafa Taşdemir ◽

Ünal Öztekin ◽

Mehmet Canikoğlu ◽

Hafize Aktaş

Keyword(s):

Erectile Dysfunction ◽

Erectile Function ◽

Doppler Ultrasonography ◽

Oral Treatment ◽

Post Treatment ◽

Cholesterol Levels ◽

Before And After ◽

Function Domain ◽

Lipid Parameters ◽

High Triglyceride

Objective: The aim of this study is to investigate the effect of hyperlipidemia on the development of erectile dysfunction (ED) in hyperlipidemic patients with ED. Materials and Methods: Twenty-five patients who applied to the radiology clinic were included in the study. All patients have only hyperlipidemia as a risk factor of ED. The patients were evaluated in terms of ED by using International Index of Erectile Function (IIEF) form. Before and after oral treatment with daily doses of 10 mg atorvastatin, all parameters were measured. Paired t-test was used to compare vascular velocities between lipid profiles and Erectile Function Domain Scores (EFDS) and IIEFs, before and after treatment separately. Results: Cholesterol levels of 96% of patients were higher than 200 mg/dl and 52% of them had abnormal penile Doppler ultrasonography (PDU) findings. Patients with abnormal PDU findings had lower cholesterol levels than those with normal PDU findings. Significant differences existed between patients with normal and abnormal PDU in the high triglyceride group as for pre-, and post-treatment values . Pre-, and post-treatment EFD and IIEF scores were comparable. Conclusion: It can be said that a relationship exists between hyperlipidemia and erectile dysfunction. Therefore, lipid profile of a patient admitted with ED may be analyzed routinely

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S&T-63 EFFECT OF PROSTATE BIOPSY ON ERECTILE FUNCTION IN NON ERECTILE DYSFUNCTION MEN A PROSPECTIVE STUDY.

The Journal of Urology ◽

10.1016/j.juro.2016.02.2892 ◽

2016 ◽

Vol 195 (4S) ◽

Author(s):

Edgar Linden-Castro ◽

Marcela Pelayo-Nieto ◽

Daniel Espinosa-perezgrovas ◽

Adolfo Gonzalez-Serrano ◽

Gabriel Catalan-Quinto ◽

...

Keyword(s):

Erectile Dysfunction ◽

Prospective Study ◽

Prostate Biopsy ◽

Erectile Function ◽

A Prospective Study

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Angiotensin Receptor Blockers for Erectile Dysfunction in Hypertensive Men: A Brief Meta-Analysis of Randomized Control Trials

American Journal of Men s Health ◽

10.1177/1557988319892735 ◽

2019 ◽

Vol 13 (6) ◽

pp. 155798831989273

Author(s):

Shaiful Bahari Ismail ◽

Norhayati Mohd Noor ◽

Nik Hazlina Nik Hussain ◽

Zaharah Sulaiman ◽

Muhammad Asyraf Shamsudin ◽

...

Keyword(s):

Erectile Dysfunction ◽

Sexual Activity ◽

Erectile Function ◽

Antihypertensive Drugs ◽

Angiotensin Receptor Blockers ◽

Random Sequence ◽

Meta Analysis ◽

Selective Reporting ◽

Angiotensin Receptor ◽

Receptor Blockers

Erectile dysfunction is common in adult men, particularly those with hypertension and diabetes. The present study determines the effectiveness of angiotensin receptor blocker (ARB) drugs on erectile function in hypertensive male adults. For this purpose, CENTRAL and MEDLINE and reference lists of the articles were searched. The randomized controlled trials (RCTs) were selected that compared ARBs with conventional therapy or no treatment in men of any ethnicity who were presented with hypertension and/or diabetes. A total four trials that had 2,809 men were included. Three trials reported adequate random sequence allocation, two reported adequate blinding. Attrition bias is low in one of the included studies. All three studies are of low risk of selective reporting bias. There was an improvement in sexual activity with ARBs (valsartan) (mean difference (MD): 0.71, 95% Confidence Interval (CI) 0.66 to 0.76, I2 statistic = 0%). However, the erectile functions did not increase significantly in ARBs (losartan or telmisartan) treated men as compared to control or placebo ( n = 203 vs n = 232; MD: 1.36; 95% CI: −0.97 to −3.69; I2 statistic = 80%). These results suggested that ARBs significantly improved sexual activity among hypertensive men. However, the erectile function was not significantly improved in ARBs treated men as compared to the control or placebo-treated. There were limited studies available. Hence, additional studies are needed to support findings from this review. ARBs should be considered when prescribing antihypertensive drugs to men.

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The impact of sexual activity on serum hormone levels after penile prosthesis implantation

Archivio Italiano di Urologia e Andrologia ◽

10.4081/aiua.2014.3.193 ◽

2014 ◽

Vol 86 (3) ◽

pp. 193

Author(s):

Onder Canguven ◽

Raidh A. Talib ◽

Ahmed Shamsodini ◽

Abdulla Al Ansari

Keyword(s):

Erectile Dysfunction ◽

Luteinizing Hormone ◽

Sexual Activity ◽

Penile Prosthesis ◽

Sex Hormone ◽

Prosthesis Implantation ◽

Hormone Levels ◽

Testosterone Levels ◽

Before And After ◽

The Impact

Objectives: Penile prosthesis implantation is the final treatment option for patients who have erectile dysfunction. Most of the patients use their penile prosthesis successfully and frequently for penile-vaginal intercourse. Previous literature showed that decrease in sexual activity resulted in decreased serum testosterone levels and vice versa. The aim of this study was to examine the impact of sexual activity on serum sex hormone levels after penile prosthesis usage. Material and methods: In this study, we examined sixtyseven patients for their sex hormone changes who had penile prosthesis surgery 2.7 ± 1.5 years ago. Results: Patients were using their penile prosthesis for sexual activity with a mean of 9.9 ± 5.7 times per month. Dehydroepiandrosterone sulfate was significantly higher compared to pre-surgery results (5.3 ± 2.6 vs 4.5 ± 2.9; p = 0.031). Mean serum total testosterone levels of patients before and after penile prosthesis usage were clinically significant 15.78 ± 4.8 nmol/L and 16.5 ± 6.1 nmol/L, respectively. Mean serum luteinizing hormone levels of patients before and after penile prosthesis usage were 3.98 ± 2.16 IU/L and 5.47 ± 4.76 IU/L, respectively. No statistical significance difference was observed in the mean total and free testosterone, estradiol and luteinizing hormone levels between pre- and post-surgery. Conclusion: This study results demonstrated that sexual activity changed sex hormone levels positively among those men who were implanted penile prosthesis because of erectile dysfunction.

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Erectile Function and Sexual Satisfaction Before and After Penile Prosthesis Implantation in Radical Prostatectomy Patients: A Comparison with Patients with Vasculogenic Erectile Dysfunction

Journal of Sexual Medicine ◽

10.1111/j.1743-6109.2011.02466.x ◽

2011 ◽

Vol 8 (12) ◽

pp. 3479-3486 ◽

Cited By ~ 29

Author(s):

Johann Menard ◽

Jack-Charles Tremeaux ◽

Antoine Faix ◽

Jean Pierrevelcin ◽

Frédéric Staerman

Keyword(s):

Erectile Dysfunction ◽

Radical Prostatectomy ◽

Sexual Satisfaction ◽

Erectile Function ◽

Penile Prosthesis ◽

Prosthesis Implantation ◽

Before And After ◽

Vasculogenic Erectile Dysfunction

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Effects of sexual arousal on vibrotactile detection thresholds in aged men with and without erectile dysfunction

Sexual Health ◽

10.1071/sh07096 ◽

2008 ◽

Vol 5 (4) ◽

pp. 347 ◽

Cited By ~ 2

Author(s):

Chuanshu Jiao ◽

Peter K. Knight ◽

Patricia Weerakoon ◽

Brett D. McCann ◽

A. Bulent Turman

Keyword(s):

Erectile Dysfunction ◽

Sexual Arousal ◽

Repeated Measures ◽

Erectile Function ◽

Staircase Method ◽

Detection Thresholds ◽

Before And After ◽

The Right ◽

And Control ◽

The Erotic

Background: Erectile dysfunction (ED) is a common problem in ageing men. Abnormalities in sexual arousal may contribute to its development, and to the failure of pharmacological therapies. However, there are few objective ways of assessing arousal. Sexual arousal has been shown to affect vibrotactile detection thresholds (VDT) in young, healthy men. The present study assessed the effects of sexual arousal on VDT in middle-aged men with and without ED in order to determine whether differences exist between the groups and if such differences may be useful in the evaluation of ED. Methods: VDT in the right index finger of 15 heterosexual men (mean age 74.3 ± 6.0 years) who had been formally diagnosed with ED (ED group) and 16 men (mean age 68.0 ± 6.6 years) who reported no sexual dysfunction in the past 6 months (erectile function (EF) group) were measured before and after watching erotic and control videos using a forced-choice, staircase method at frequencies of 30, 60 and 100 Hz. A mechanical stimulator was used to produce the vibratory stimulus. Results were analysed using repeated-measures analysis of variance. Results: There was no significant effect of watching the erotic video on VDT in subjects in the ED group. In the EF group, VDT was significantly lower at 60 and 100 Hz after watching the erotic video. There was no change in VDT after watching the control video in either group. Conclusion: In response to sexual arousal, VDT in ageing men with normal erectile function decrease, whereas VDT in ageing men with ED remain unchanged.

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