scholarly journals Breast metastasis from multiple primary rhabdomyosarcoma in upper extremity

2012 ◽  
Vol 2 (1) ◽  
pp. 25 ◽  
Author(s):  
Ramesh Omranipour ◽  
Mohamad Reza Hadi
Keyword(s):  
Upper Extremity ◽  
Lung Metastasis ◽  
Clinical Course ◽  
Excisional Biopsy ◽  
Left Breast ◽  
Adolescent Females ◽  
Breast Metastasis ◽  
Multiple Primary ◽  
One Year ◽  
The Right

We report a 16-year-old girl with a multiple primary rhabdomyosarcoma of right upper extremity who developed contralateral breast metastasis in her clinical course. She was diagnosed to have multiple primary rhabdomyosarcoma of the right upper extremity with lung metastasis one year prior to finding a mass in her left breast. The excisional biopsy of the breast mass confirmed metastatic rhabdomyosarcoma. Despite aggressive chemotherapy and subcutaneous total mastectomy, she developed a widespread bone and lung metastasis in few months and expired. Metastatic rhabdomyosarcoma of the breast is very rare but it should be considered in adolescent females with primary alveolar rhabdomyosarcoma, specially located on an extremity.

scholarly journals Macrodystrophia Lipomatosa Extending Into the Abdominal Wall and Breast: A Case Report

2020 ◽  
Author(s):  
Jian Liu ◽  
Jiaming Sun ◽  
Liang Guo ◽  
Zhenxing Wang ◽  
Nengqiang Guo
Keyword(s):  
Computed Tomography ◽  
Abdominal Wall ◽  
Lower Limb ◽  
Rare Case ◽  
Left Breast ◽  
Fatty Tissue ◽  
X Ray ◽  
Macrodystrophia Lipomatosa ◽  
One Year ◽  
The Right

Abstract BackgroundMacrodystrophia lipomatosa is a rare nonhereditary congenital gigantism, characterized by overgrowth of mesenchymal and fibro-adipose tissue, affecting one or more digits of the extremities. Here, we report a rare case of macrodystrophia lipomatosa of the entire right lower limb with extension of hypertrophied fatty tissue into the abdominal wall and breast. Case presentationA 32 years old woman was born with abnormally elongated and thickened right leg, and the condition aggravated gradually. The disease was multiple, including the right leg, right abdominal wall, and the left breast were also involved. The patient mainly complained that she was unable to walk but with the knee flexed. Physical examination revealed that the elongation and thickening was proportional to the left leg, and the involved joints were malformed and dysfunction. X-ray and Computed tomography angiography (CTA) showed the bones and vessels were elongated and thickened, and the joints were hypertrophic and swollen. Amputation, volume reduction and liposuction was performed on the lesions. Histological examination could see abnormal fibro-fatty tissue hyperplasia, the adipocytes were invasive, and part of muscles presented fat degeneration. The lesions showed no recurrence for one year after surgery.ConclusionAfter reviewing the literature of the macrodystrophia lipomatosa, we believed that our case was rare because the hypertrophied fatty tissue extended into the abdominal wall and breast, which was different from former studies and had not been documented worldwide. This novel case will further deepens the understanding of this disease, and will be useful for clinicians in diagnosing it.

Lingual Schwannoma Involving The Posterior Lateral Border Of The Tongue In A Young Individual: Case Report

2008 ◽  
Vol 33 (1) ◽  
pp. 59-62 ◽  
Author(s):  
Luciano José Pereira ◽  
Patrícia Peres Iucif Pereira ◽  
João de Paula dos Santos ◽  
Viator Ferreira Reis Filho ◽  
Paulo Roberto Dominguete ◽  
...  
Keyword(s):  
Case Reports ◽  
Neck Region ◽  
Excisional Biopsy ◽  
Individual Case ◽  
Autonomic Nerves ◽  
Current Case ◽  
Lateral Border ◽  
Individual Case Report ◽  
One Year ◽  
The Right

A schwannoma, also called neurilemmoma, is a benign, encapsulated, slow growing tumor, arising from the neural sheath's Schwann cells of the peripheral, cranial or autonomic nerves. The etiology is unknown, there is no gender preference and the tumors occur most commonly between the ages of 20 and 50 years. Approximately 25–48 % of these tumors occur in the head and neck region, with only 1% occurring in the mouth. The current case reports a schwannoma of the tongue, found in a 12 year-old boy. The lesion was present for 6 months. The clinical examination revealed a 1.5x1.0 cm, sessile, rubbery, non-tender, non-ulcerated mass on the right posterior lateral border of the tongue. An excisional biopsy was performed under local anesthesia. The histological sections showed a circumscribed submucosal nodule composed of spindle cells with thin wavy nuclei arranged as typical Antoni A (with Verocay bodies) and Antoni B areas. Nuclear palisading distribution (typical of a schwannoma) was readily identifiable. The patient was recurrence free after one year.

scholarly journals Sebaceous Carcinoma of the Vulva: An Unexpected Diagnosis and Literature Review

2022 ◽  
Vol 35 (1) ◽  
pp. 63
Author(s):  
Ana Carolina Rocha ◽  
Maria Inês Sá ◽  
Carlos Abrantes ◽  
Rita Sousa
Keyword(s):  
Topical Steroid ◽  
Excisional Biopsy ◽  
Sebaceous Carcinoma ◽  
Sebaceous Glands ◽  
Post Surgery ◽  
Previously Treated ◽  
First Recurrence ◽  
Rare Malignancy ◽  
One Year ◽  
The Right

Sebaceous carcinoma of the vulva is a rare malignancy of the sebaceous glands, with potentially aggressive behaviour, that is usually found in the peri-ocular area. Nonetheless, there are sebaceous glands in the vulva and this diagnosis is especially rare, with only ten cases described in the literature. We report a case of 78-year-old female patient who presented with vulvar pruritus, previously treated with topical steroid and antifungal treatments, without improvement. The vulvar examination showed a visible yellow papule, 12 x 10 mm on the right major labia, which was biopsied and the microscopic examination revealed an invasive sebaceous carcinoma of the vulva, with an in situ component. We performed an uneventful excisional biopsy, followed by a subsequent margin widening. Three months after the diagnosis, she presented with the first recurrence. Two and half years after the diagnosis, she recurred with a larger lesion (13 mm) in the upper half of small right lip, more than 10 mm away from the midline. In a multidisciplinary meeting it was decided that the patient should undergo partial right vulvectomy with homolateral inguino-femoral sentinel node biopsy (one negative node). There was no evidence of recurrence one-year post-surgery.

Unusual Presentation of Breast Metastasis Mimicking Skin Abscess

2020 ◽  
Author(s):  
Armaghan Kazeminejad ◽  
Mohammad Jafar Ghahari ◽  
Ali Mirabi ◽  
Lotfollah Davoodi ◽  
Mohammad Tabarestani
Keyword(s):  
Breast Cancer ◽  
Clinical Presentation ◽  
Left Breast ◽  
Breast Metastasis ◽  
Common Site ◽  
Cutaneous Metastases ◽  
Invasive Ductal Breast Carcinoma ◽  
Erythrocyte Sedimentation ◽  
History Of ◽  
One Year

The primary malignant tumor that most commonly metastasizes to the skin in women is breast cancer and manifest variety forms of clinical presentation. Breast cancer has the ability to metastasize to any site such as the ovaries, lung, liver, bone, brain, gastrointestinal tract and skin. The skin is not a common site for metastatic spread. We would like to report a case of a 56 years old female patient with an infectious mass in her left inframammary fold with discharge. The patients had a one-year history of left breast pruritus and with a mass which increased in size over two months. There was axillary lymphadenopathy, tenderness, and erythema of breast skin around the mass in the physical examination and just elevated erythrocyte sedimentation rate in laboratory tests. The patient did not benefit from antimicrobial therapy. The histological examination revealed a tumor with sheets of malignant cells and many necrotic areas. The diagnosis was invasive ductal breast carcinoma, cutaneous metastases, and lymphatic embolization.

Primary pediatric cardiac tumors: a 17 year experience

1999 ◽  
Vol 9 (2) ◽  
pp. 155-162 ◽  
Author(s):  
Denver Sallee ◽  
Michael L. Spector ◽  
Daniel W. van Heeckeren ◽  
Chandrakant R. Patel
Keyword(s):  
Clinical Course ◽  
Tumor Resection ◽  
Cardiac Tumors ◽  
Fetal Ultrasound ◽  
Electrophysiologic Study ◽  
Fetal Ultrasonography ◽  
Benign Histology ◽  
One Year ◽  
The Right

AbstractWe reviewed 22 cases of primary pediatric cardiac tumors followed at our institution from January 1981 through November 1997, analyzing them by subtype, age and manner of presentation, location, associated findings, interventions, and clinical course. Rhabdomyomas were the most common (11), followed by intrapericardial teratomas (2), myxomas (1), fibromas (1), hemangiomas (1), mesotheliomas (1), and rhabdomyosarcomas (1), with 4 undetermined tumors. The majority (77%) of tumors were diagnosed before the age of one year, including six prenatally. The most common presentations were murmurs (5), arrhythmias (5), and abnormal screening fetal ultrasound examinations (4). Tumors were located most frequently in the right ventricle (13) and left ventricle (7), with multiple tumors being present in 10 cases. Eight patients (36%) had associated arrhythmias or conduction abnormalities, and of the 11 patients with rhabdomyomas, tuberous sclerosis was diagnosed in 8. Eight patients underwent cardiac catheterization, including two for electrophysiologic study with radiofrequency ablation, and seven patients had complete or partial tumor resection. The follow-up period ranged from 2 months to 15 years, and there were 3 tumor-related deaths. Therefore, despite the benign histology of most primary pediatric cardiac tumors, there may be significant associated morbidity and occasional mortality. As echocardiographic techniques such as fetal ultrasonography have continued to improve, however, these cardiac tumors have increasingly been detected early before significant symptoms develop.

scholarly journals Demographic and Clinical Profile of Tuberculous Mastitis Patients at Tebet General Hospital, Jakarta

2019 ◽  
Vol 3 (2) ◽  
pp. 32
Author(s):  
Desak Ketut Nari Swari Pramegia ◽  
Rio Putratama Achmad Faried ◽  
Kelvin Setiawan ◽  
Bramastha Aires Rosadi ◽  
Terry Renata Lawanto
Keyword(s):  
General Hospital ◽  
Left Breast ◽  
The Body ◽  
Clinical Profile ◽  
Hiv Test ◽  
Unilateral Involvement ◽  
The Mean ◽  
One Year ◽  
The Right ◽  
Possible Cause

Aim: Objective of the study is to find out the demographic and clinical profile of tuberculous mastitis (TM) patients. Methods: The study was carried out for a period of one year from August 2017 to August 2018 at Tebet General Hospital. Histopathologically diagnosed cases of TM were retrospectively studied. Results: All eight patients diagnosed as suffering from TM were females with the mean age of 37.25 years. Of these, two patients were lactating, six others were not, and 75% were multiparous. Unilateral involvement was observed in all cases. The right breast was affected in 62.5% and left breast in 37.5% cases. Patients presented with a solitary lump on one breast (87.5%), swelling of the breast (37.5%), and breast pain (100%). In the present study, two of the patients had previous positive tuberculosis (TB) contact and more than half found to be below an average economic level. All the patients were negative on the HIV test; also, there was no focus of TB elsewhere in the body. Conclusion: Tuberculosis should be considered as one possible cause of either mastitis or breast abscess. Histopathology examination played an important role in the diagnosis of TM. Standardized sequence for the diagnosis of TM is needed to increase awareness of the disease.

Starting off on the right foot: One year of behavior analysis in practice and relative cost.

2008 ◽  
Vol 4 (2) ◽  
pp. 212-226 ◽  
Author(s):  
Jeremy H. Greenberg ◽  
Rosa C. Martinez
Keyword(s):  
Behavior Analysis ◽  
Relative Cost ◽  
One Year ◽  
The Right

Giant right coronary artery aneurysm

2020 ◽  
Vol 28 ◽  
pp. 1-3
Author(s):  
Alexandre Bonfim ◽  
Ronald Souza ◽  
Sérgio Beraldo ◽  
Frederico Nunes ◽  
Daniel Beraldo
Keyword(s):  
Coronary Artery ◽  
Right Coronary Artery ◽  
Coronary Artery Aneurysm ◽  
Clinical Course ◽  
Artery Aneurysm ◽  
Giant Aneurysm ◽  
Coronary Artery Aneurysms ◽  
History Of ◽  
Artery Disease ◽  
The Right

Right coronary artery aneurysms are rare and may result from severe coronary disease, with few cases described in the literature. Mortality is high, and therapy is still controversial. We report the case of a 72-year-old woman with arterial hypertension, and a family history of coronary artery disease, who evolved for 2 months with episodes of palpitations and dyspnea on moderate exertion. During the evaluation, a giant aneurysm was found in the proximal third of the right coronary artery. The patient underwent surgical treatment with grafting of the radial artery to the right coronary artery and ligation of the aneurysmal sac, with good clinical course.

scholarly journals Bilateral Phyllodes Giant Tumor. A Case Report Analyzed by Array-CGH

Diagnostics ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 825
Author(s):  
Francesco Fortarezza ◽  
Federica Pezzuto ◽  
Gerardo Cazzato ◽  
Clelia Punzo ◽  
Antonio d’Amati ◽  
...  
Keyword(s):  
Array Cgh ◽  
Phyllodes Tumor ◽  
Molecular Classification ◽  
Left Breast ◽  
Comparative Genomic ◽  
Fish Analysis ◽  
Molecular Tests ◽  
Giant Tumor ◽  
Metastatic Risk ◽  
The Right

The breast phyllodes tumor is a biphasic tumor that accounts for less than of 1% of all breast neoplasms. It is classified as benign, borderline, or malignant, and can mimic benign masses. Some recurrent alterations have been identified. However, a precise molecular classification of these tumors has not yet been established. Herein, we describe a case of a 43-year-old woman that was admitted to the emergency room for a significant bleeding from the breast skin. A voluminous ulcerative mass of the left breast and multiple nodules with micro-calcifications on the right side were detected at a physical examination. A left total mastectomy and a nodulectomy of the right breast was performed. The histological diagnosis of the surgical specimens reported a bilateral giant phyllodes tumor, showing malignant features on the left and borderline characteristics associated with a fibroadenoma on the right. A further molecular analysis was carried out by an array-Comparative Genomic Hybridization (CGH) to characterize copy-number alterations. Many losses were detected in the malignant mass, involving several tumor suppressor genes. These findings could explain the malignant growth and the metastatic risk. In our study, genomic profiling by an array-CGH revealed a greater chromosomal instability in the borderline mass (40 total defects) than in the malignant (19 total defects) giant phyllodes tumor, reflecting the tumor heterogeneity. Should our results be confirmed with more sensitive and specific molecular tests (DNA sequencing and FISH analysis), they could allow a better selection of patients with adverse pathological features, thus optimizing and improving patient’s management.

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