scholarly journals Invasive aspergillosis in an immunocompetent patient with fever and a cardiac mass

2011 ◽  
Vol 3 (2) ◽  
pp. 12 ◽  
Author(s):  
Matthew LaBarbera ◽  
Lester B. Jacobson

Invasive aspergillosis is an often fatal disease that usually occurs in immunocompromised patients. We report a case of invasive aspergillosis presenting as a febrile respiratory infection with a cardiac mass in an immunocompetent patient. Invasive aspergillosis should be considered in the differential diagnosis of an otherwise undiagnosed febrile respiratory illness, even in immunocompetent patients. Echocardiography should be peformed to evaluate for endocarditis in such cases. Prompt initiation of appropriate antifungal therapy is warranted, even before the diagnosis of invasive aspergillosis is confirmed.

2008 ◽  
Vol 126 (4) ◽  
pp. 227-228 ◽  
Author(s):  
Daniel Sáenz-Abad ◽  
Santiago Letona-Carbajo ◽  
José Luis de Benito-Arévalo ◽  
Isabel Sanioaquín-Conde ◽  
Francisco José Ruiz-Ruiz

CONTEXT: Tuberculosis of the prostate has mainly been described in immunocompromised patients. However, it can exceptionally be found as an isolated lesion in immunocompetent patients. CASE REPORT: We report a case of prostatic tuberculosis in a young, healthy and immunocompetent patient with unremarkable findings from intravenous urographic examination. Computed tomography showed an abscess in the prostate and Mycobacterium tuberculosis was isolated in a urine culture. Treatment with isoniazid, rifampin and pyrazinamide was successful.


2016 ◽  
Vol 7 (1) ◽  
pp. 30-34 ◽  
Author(s):  
Christine Hessler ◽  
Carol A. Kauffman ◽  
Felicia C. Chow

Chronic meningitis of unknown etiology is a vexing illness for patients and clinicians. Identification of the correct pathogen can be challenging and time consuming, leading to delays in appropriate treatment. Although Sporothrix schenckii is a recognized and treatable cause of chronic meningitis, neurologists and infectious diseases physicians may not regularly evaluate for Sporothrix infection. We describe an immunocompetent patient with chronic meningitis who partially responded to empiric fluconazole. Prompted by a recent culture-confirmed case of meningeal sporotrichosis, we tested for S schenckii antibodies from the cerebrospinal fluid, which were positive. His clinical and functional status improved, and the S schenckii antibody titer decreased with itraconazole therapy. Clinicians should consider S schenckii in the differential diagnosis for chronic meningitis, even in immunocompetent patients, particularly when the clinical picture does not respond to standard empiric therapy.


2020 ◽  
Vol 12 (1) ◽  
pp. 58-62
Author(s):  
Johanna Cecilia Enríquez Cruz ◽  
Adriana Elizabeth Araujo Yánez ◽  
Sayonara del Rocío Zaputt Cabrera

BACKGROUND: Disseminated cutaneous Herpes Zoster is defined as the presence of more than 20 vesicles outside the area and adjacencies of the primarily affected dermatome, the involvement of more than 2 contiguous dermatomes or the presence of systemic disease. Its prevalence among immunodepressed patients is 10- 40%, but between immunocompetent patients only isolated cases are reported. We present a case of an elderly immunocompetent patient, with no pathological history, that developed HZCD. CASE REPORT: An 89 year old woman, with no medical background, presented with 10 day evolution itchy, painful blistering lesions on the inner right thigh and the proximal third of the ipsilateral leg. Days after the lesions disseminated and the patient received topical treatment, she couldn’t specify the treatment; after 3 days her general condition worsened, and she was brought to the Emergency Room. EVOlUTION: Patient was diagnosed with Disseminated Herpes Zoster. She had a good outcome, after completing the intravenous antiviral treatment and she was discharged with no complications, after 10 days of being hospitalized. CONClUSION: Diagnosis of disseminated herpes zoster should be considered in both immunocompetent and immunocompromised patients. The outcome strongly depends on the promptness of the specific therapy instauration. KEYWORDS: HERPES ZOSTER, SKIN DISEASES, VESICULOBULLOUS, ANTIVIRAL AGENTS


2019 ◽  
Vol 12 (5) ◽  
pp. e228961
Author(s):  
Nitin Agarwal ◽  
Ashish Sharma ◽  
Gaurav Garg

Splenic abscess is a rare life-threatening clinical entity. There are only a handful of reported cases of spontaneous splenic abscess rupture with pneumoperitoneum. Rupture of splenic abscess associated with gas-producing pathogens may lead to pneumoperitoneum. We hereby report the case of a ruptured splenic abscess with pneumoperitoneum in a young immunocompetent woman masquerading as hollow viscus perforation peritonitis. Ruptured splenic abscess should be kept in mind for treating surgeons as a differential diagnosis of pneumoperitoneum or peritonitis, particularly for immunocompromised patients.


Author(s):  
Ridwaan Albeiruti ◽  
Fahad Chaudhary ◽  
Hiren Vallabh ◽  
Troy Krupica ◽  
Justin Kupec

The lifetime prevalence of peptic ulcer disease (PUD) is 5–10%. While PUD in immunocompetent patients is most commonly associated with Helicobacter pylori infection or the use of non-steroidal anti-inflammatory drugs (NSAIDs), other common causes of PUD must also be considered in the differential diagnosis. We describe a case of endoscopic and histological resolution of PUD related to Candida infection in a healthy, immunocompetent woman.


2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Ulku Ergene ◽  
Zeynep Akcali ◽  
Demircan Ozbalci ◽  
Nalan Nese ◽  
Sebnem Senol

Invasive aspergillosis is a major cause of morbidity and mortality in immunocompromised patients. Many cases of pulmonary, cutaneous, cerebral, and paranasal sinus aspergillosis in immunocompetent patient were defined in literature but disseminated aspergillosis is very rare. Here we present an immunocompetent case with extrapulmonary disseminated aspergillosis due toAspergillus niger, totally recovered after effective antifungal treatment with voriconazole.


2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
S. Guglielmetti ◽  
C. M. Jaccard ◽  
K. Mühlethaler ◽  
A. Bigler ◽  
D. Springe ◽  
...  

Invasive aspergillosis represents a clinical picture frequently associated with host’s immunosuppression which usually involves a high morbidity and mortality. In general, the most frequent fungal entry is the lungs with secondary hematogenous dissemination, but there are other hypotheses like a gastrointestinal portal of entry. There are some rare publications of cases with invasive aspergillosis in immunocompetent patients. We present the case of an immunocompetent patient without any risk factors except for age, ICU stay, and surgical intervention, who developed a septic shock by invasive gastrointestinal aspergillosis as primary infection. Due to the unusualness of the case, despite all the measures taken, the results were obtained postmortem. We want to emphasize the need not to underestimate the possibility for an invasive aspergillosis in an immunocompetent patient. Not only pulmonary but also gastrointestinal aspergillosis should be taken into account in the differential diagnosis to avoid a delay of treatment.


2021 ◽  
Vol 20 (3) ◽  
Author(s):  
Atikah Rozhan ◽  
Kahairi Abdullah ◽  
Zamzil Amin Asha'ari

Mycobacteria fortuitum and chelonae are a group of Rapidly Growing Mycobacteria (RGM) that can cause skin infections, most commonly in immunocompromised patients. RGM can also infect immunocompetent patients, but the disease is usually localized. Immunocompetent patients infected by RGM usually had a predisposing condition leading to the skin infection. We present a case of an immunocompetent patient with no predisposing factors, who presented with a chronic lesion on his neck that disseminated to his axilla. Culture and species identification from the skin biopsy revealed Mycobacterium fortuitum-chelonae complex. The patient was treated with a combination of surgery and multi-drug therapy. This case report highlights the rarity of cutaneous RGM infections encountered in ENT setting and the diagnostic dilemma due to the non-typical characteristics of skin lesion in RGM infections.


2016 ◽  
Vol 1 (2) ◽  
pp. 33
Author(s):  
Nurul Yaqeen Mohd Esa ◽  
Mohammad Hanafiah ◽  
Marymol Koshy ◽  
Hilmi Abdullah ◽  
Ahmad Izuanuddin Ismail ◽  
...  

Tuberculous prostatitis is an uncommon form of tuberculosis infection. It is commonly seen in immunocompromised patients and in those of middle or advanced age. The diagnosis is often not straight forward due to the nature of its presentation. We report a case of tuberculous prostatitis in a young, healthy and immunocompetent patient, who initially presented with respiratory features, followed by episodes of seizures and testicular swelling. He was finally diagnosed with tuberculous prostatitis after prostatic biopsy. This case illustrates that in a high TB prevalence environment, when symptoms warrant, there should be a high clinical suspicion coupled with a thorough approach in order to arrive at a correct diagnosis of TB prostatitis.


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