scholarly journals Rising Incidence of Diabetes in Young Adults in South Korea: A National Cohort Study

2022 ◽  
Author(s):  
Hyun Ho Choi ◽  
Giwoong Choi ◽  
Hojun Yoon ◽  
Kyoung Hwa Ha ◽  
Dae Jung Kim
Keyword(s):  
Young Adults ◽  
Cohort Study ◽  
South Korea ◽  
National Cohort ◽  
Rising Incidence

Dental healthcare utilisation among young adults who were in societal out-of-home care as children: A Swedish National Cohort Study

2018 ◽  
Vol 27 (4) ◽  
pp. 325-336 ◽  
Author(s):  
Marie Berlin ◽  
Tita Mensah ◽  
Frida Lundgren ◽  
Gunilla Klingberg ◽  
Anders Hjern ◽  
...  
Keyword(s):  
Young Adults ◽  
Cohort Study ◽  
Home Care ◽  
Healthcare Utilisation ◽  
Out Of Home Care ◽  
National Cohort

scholarly journals Juvenile delinquency, social background and suicide--a Swedish national cohort study of 992 881 young adults

2011 ◽  
Vol 40 (6) ◽  
pp. 1585-1592 ◽  
Author(s):  
E. Bjorkenstam ◽  
C. Bjorkenstam ◽  
B. Vinnerljung ◽  
J. Hallqvist ◽  
R. Ljung
Keyword(s):  
Young Adults ◽  
Cohort Study ◽  
Juvenile Delinquency ◽  
Social Background ◽  
National Cohort

scholarly journals Age Does Matter in Adolescents and Young Adults versus Older Adults with Advanced Melanoma; A National Cohort Study Comparing Tumor Characteristics, Treatment Pattern, Toxicity and Response

Cancers ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2072 ◽  
Author(s):  
Monique K. van der Kooij ◽  
Marjolein J.A.L. Wetzels ◽  
Maureen J.B. Aarts ◽  
Franchette W.P.J. van den Berkmortel ◽  
Christian U. Blank ◽  
...  
Keyword(s):  
Older Adults ◽  
Young Adults ◽  
Cohort Study ◽  
Group Performance ◽  
Advanced Melanoma ◽  
Adolescents And Young Adults ◽  
First Line ◽  
National Cohort ◽  
Baseline Characteristics ◽  
Grade 3

Cutaneous melanoma is a common type of cancer in Adolescents and Young Adults (AYAs, 15–39 years of age). However, AYAs are underrepresented in clinical trials investigating new therapies and the outcomes from these therapies for AYAs are therefore unclear. Using prospectively collected nation-wide data from the Dutch Melanoma Treatment Registry (DMTR), we compared baseline characteristics, mutational profiles, treatment strategies, grade 3–4 adverse events (AEs), responses and outcomes in AYAs (n = 210) and older adults (n = 3775) who were diagnosed with advanced melanoma between July 2013 and July 2018. Compared to older adults, AYAs were more frequently female (51% versus 40%, p = 0.001), and had a better Eastern Cooperative Oncology Group performance status (ECOG 0 in 54% versus 45%, p = 0.004). BRAF and NRAS mutations were age dependent, with more BRAF V600 mutations in AYAs (68% versus 46%) and more NRAS mutations in older adults (13% versus 21%), p < 0.001. This finding translated in distinct first-line treatment patterns, where AYAs received more initial targeted therapy. Overall, grade 3–4 AE percentages following first-line systemic treatment were similar for AYAs and older adults; anti-PD-1 (7% versus 14%, p = 0.25), anti-CTLA-4 (16% versus 33%, p = 0.12), anti-PD-1 + anti-CTLA-4 (67% versus 56%, p = 0.34) and BRAF/MEK-inhibition (14% versus 23%, p = 0.06). Following anti-CTLA-4 treatment, no AYAs experienced a grade 3–4 colitis, while 17% of the older adults did (p = 0.046). There was no difference in response to treatment between AYAs and older adults. The longer overall survival observed in AYAs (hazard ratio (HR) 0.7; 95% CI 0.6–0.8) was explained by the increased cumulative incidence of non-melanoma related deaths in older adults (sub-distribution HR 2.8; 95% CI 1.5–4.9), calculated by competing risk analysis. The results of our national cohort study show that baseline characteristics and mutational profiles differ between AYAs and older adults with advanced melanoma, leading to different treatment choices made in daily practice. Once treatment is initiated, AYAs and older adults show similar tumor responses and melanoma-specific survival.

Preterm Infants as Young Adults: A Swedish National Cohort Study

PEDIATRICS ◽  
2007 ◽  
Vol 120 (1) ◽  
pp. 70-77 ◽  
Author(s):  
K. Lindstrom ◽  
B. Winbladh ◽  
B. Haglund ◽  
A. Hjern
Keyword(s):  
Young Adults ◽  
Cohort Study ◽  
Preterm Infants ◽  
National Cohort

Incidence and prevalence of uveitis in South Korea: a nationwide cohort study

2017 ◽  
Vol 102 (1) ◽  
pp. 79-83 ◽  
Author(s):  
Tyler Hyungtaek Rim ◽  
Sung Soo Kim ◽  
Don-Il Ham ◽  
Seung-Young Yu ◽  
Eun Jee Chung ◽  
...  
Keyword(s):  
Cohort Study ◽  
South Korea ◽  
Anterior Uveitis ◽  
Sociodemographic Factors ◽  
Uveitis Anterior ◽  
Disease Definition ◽  
Classification Of Diseases ◽  
National Cohort ◽  
The Usa ◽  
Associated Risk Factors

AimTo evaluate the incidence and prevalence of uveitis and associated risk factors in South Korea.MethodsFor this retrospective national cohort study, approximately 1 000 000 Korean residents were randomly selected from the Korean National Health Insurance Service database. Uveitis was defined according to the Korean Classification of Diseases. The uveitis incidence and prevalence were calculated. Sociodemographic factors and comorbidities associated with uveitis were evaluated via Cox proportional regression models.ResultsA total of 1 094 440 subjects were evaluated over 7 051 346 person-years (mean follow-up: 6.44 years). Overall, 7447 newly developed uveitis cases were identified during the period of 2007–2013; the average incidence of uveitis was 10.6 per 10 000 person-years (95% CI 10.3 to 10.8). The average incidences of anterior and non-anterior uveitis were 9.0 and 1.5 per 10 000 person-years, respectively. The prevalence rates of uveitis, anterior uveitis and non-anterior uveitis were 17.3, 15.0 and 2.3 per 10 000 persons, respectively, during the period of 2007–2013. Increasing age, male sex, residing in a relatively rural area and high income were associated with uveitis, along with Behçet’s disease, juvenile idiopathic arthritis, ankylosing spondylitis, systemic lupus erythematous, ulcerative colitis and tuberculosis.ConclusionsThe overall incidence of uveitis in Korea was similar to those reported in Taiwan and the USA. Despite a potentially inaccurate disease definition, claims data may be useful for monitoring the substantial uveitis burden in South Korea.

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