scholarly journals Human parvovirus B19-induced anaemia in pre-school children in Ilorin, Nigeria

Author(s):  
Oluwaseyi S. Ashaka ◽  
Olajide O. Agbede ◽  
Adesuyi A. Omoare ◽  
Samuel K. Ernest

Sera collected from 57 anaemic and 115 non-anaemic age-matched pre-school children in Ilorin, Nigeria, between November 2014 and December 2015 were assayed for human parvovirus B19-specific IgM antibodies by using the enzyme linked immunosorbent assay technique. A total of 17 (29.8%) anaemic children and 18 (15.7%) non-anaemic children were positive for parvovirus B19 infection. Infection with parvovirus B19 is common in this population, and screening for the virus during differential diagnosis is recommended.

1986 ◽  
Vol 24 (4) ◽  
pp. 522-526 ◽  
Author(s):  
L J Anderson ◽  
C Tsou ◽  
R A Parker ◽  
T L Chorba ◽  
H Wulff ◽  
...  

1992 ◽  
Vol 66 (4) ◽  
pp. 434-440 ◽  
Author(s):  
Yasuko MATSUNAGA ◽  
Shudo YAMAZAKI ◽  
Yasuo MORITSUGU ◽  
Yasushi KUWABARA ◽  
Masanori NISHIGAKI

1996 ◽  
Vol 38 (5) ◽  
pp. 323-328 ◽  
Author(s):  
Solange A. Oliveira ◽  
Antonio B. Brandão ◽  
Daniele G. Fernandes ◽  
Lilian R. Bettini ◽  
Anamaria B. Carvalho ◽  
...  

From March 1994 to November 1995 24 cases of human parvovirus B19 infection were seen at the Infectious Diseases Department of the Hospital Universitário Antônio Pedro, Niterói - RJ. Serum samples for IgM detection (capture enzyme immunoassay) were positive from the 1st to the 27th day after the onset of the exathema. The classical features of erythema infectiosum (slapped cheecked syndrome) were observed in 8 (33.3%) cases all of them children. Eight patients (6 adults and 2 children) presented a symmetrical polyartropathy, seen more frequently in women. These results show that B19 infection diagnosis is difficult when the disease does not present the classical features and because of the frequent involvement of the joints this infection should be considered in the differential diagnosis of early rheumatoid arthritis.


2021 ◽  
Vol 15 (2) ◽  
pp. 10-15
Author(s):  
Richard Yomi Akele ◽  
Jennifer Tamuno Abelekum ◽  
Bernard Oluwapelum Oluboyo ◽  
Janet Funmilayo Akinseye ◽  
Seyi Samson Enitan ◽  
...  

Background: Human Parvovirus B19 (B19V) is a DNA virus, transmitted through respiratory secretions, hand-to-mouth-contact, blood transfusion and trans-placental transfer. It causes high mortality and morbidity in pregnant women, thus contributing to poor maternal and child health. B19V has been neglected due to dearth of epidemiological data. The aim of this study was to determine the sero-prevalence of Human Parvovirus B19 antibodies among pregnant women attending antenatal clinic at Federal Teaching Hospital Ido-Ekiti, Nigeria. Materials and Methods: This cross-sectional study enrolled pregnant women attending Federal Teaching Hospital Ido-Ekiti from January to May 2019 to obtain sero-epidemiological data. One hundred and twenty-two (122) consenting pregnant women were enrolled following institutional ethical approval. They were administered structured questionnaire and venous blood was collected in plain tubes for serum extraction. Sera samples were analyzed for IgG and IgM antibodies using the enzyme linked immunosorbent assay method. Percentages, median, chi-square and multivariate analysis were carried out using SPSS version 17. Results: The prevalence of IgG was 44.3% (54/122), IgM 41.8% (51/122), and IgG/IgM 28.7% (35/122) leaving 55.7% (68/122) of the population uninfected. The median age of participants was 22 (Interquartile range 18-25) years among which 36-45years had the highest prevalence which was not statistically significant (p=0.09 4.75). There was association between miscarriage, still birth, history of blood transfusion and prevalence of Human Parvovirus B19 (p<0.05). Conclusion: There is a high Prevalence of B19V among pregnant women attending antenatal clinic in this study. This underscores the need for testing and immunization of pregnant women against B19V.


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