scholarly journals The management of non-melanocytic skin malignancies of the scalp and calvarium

2014 ◽  
Vol 47 (01) ◽  
pp. 36-42 ◽  
Author(s):  
Harun Çöloğlu ◽  
Burak Özkan ◽  
Mesut Şener ◽  
Ahmet Çağri Uysal ◽  
Hüseyin Borman
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Local Excision ◽  
Squamous Cell ◽  
Wide Local Excision ◽  
Locally Advanced ◽  
Histopathological Diagnosis ◽  
Full Thickness ◽  
Adjacent Structures

ABSTRACT Background: The management of advanced cutaneous malignancies has been controversial. Thirteen patients with nonmelanoma skin neoplasias that had invaded the bone of the calvarium and scalp were treated in our centre. Objective: The purpose of this study was to evaluate our experience in treating these malignancies with scalp resection and full or partial thickness cranium reconstruction. Patients and Methods: From June 2008 to March 2012, thirteen patients with locally advanced tumours of the scalp invading the calvarium were treated with wide local excision of the scalp combined with an underlying craniectomy and dural resection if needed. Results: Using histopathological diagnosis eleven patients were diagnosed with basal cell carcinoma and two patients with squamous cell carcinoma. A full thickness cranium resection was performed in seven patients and partial in six patients. Conclusion: These large cancers occasionally invade adjacent structures, as well as bone, presenting a challenging surgical problem. In general, giant rotational or island scalp flaps and free tissue transfers are needed to close the area. Finding clean margins are an important part of treating patients with bone involvement and can usually be attained using outer tabula curettage thus preventing unnecessary morbidity.

scholarly journals Squamous Cell Carcinoma of Nose: An Unusual Presentation

2011 ◽  
Vol 4 (3) ◽  
pp. 166-167
Author(s):  
Aseem Mishra ◽  
Smita K Nagle ◽  
Vikram Oberoi ◽  
Mohan Vasant Jagade ◽  
Vimal Kasbekar
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Human Papilloma Virus ◽  
Cell Carcinoma ◽  
Local Excision ◽  
Squamous Cell ◽  
Wide Local Excision ◽  
Histopathological Diagnosis ◽  
Papilloma Virus ◽  
Nasal Vestibule

ABSTRACT Most commonly, a carcinoma of nose is a basal cell carcinoma and a squamous cell carcinoma commonly arise from the dorsum of the nose. We present here a case of 35-year-old female with a squamous cell carcinoma of the nasal vestibule, which started as a wart and was very slowly progressive, until it was excised by a practitioner in a village. It then progressed rapidly and presented to us. The mass appeared a squamous cell carcinoma arising from nasal vestibule. The wart-like presentation also associates the etiology of squamous cell carcinoma to human papilloma virus and the disadvantages of excision of mass without proper histopathological diagnosis. The case was successfully managed with wide local excision with reconstruction by buccal and Estlander's flap.

scholarly journals Late malignancy after 26 years of evolution on an untreated perianal fistula

2021 ◽  
Vol 28 (1) ◽  
pp. 99-101
Author(s):  
Lucian Sorin ANDREI ◽  
◽  
Adriana Corina ANDREI ◽  
Alexandru MICU ◽  
Radu Sorin POPISTEANU ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Local Excision ◽  
Squamous Cell ◽  
Basal Cell ◽  
Perianal Fistula ◽  
Transsphincteric Fistula ◽  
History Of ◽  
Histopathological Result

Squamous cell carcinoma and basal cell carcinoma are two types of neoplasms that rarely affect the perianal region, and their etiology is still a matter for debate. We present the case of a 75 year old patient with a 26 year history of perianal fistula, who presents with purulent and fecal perianal discharge and swelling at this level. Physical examination and anoscopy detected low transsphincteric fistula. The biopsy revealed the diagnosis of squamous cell carcinoma, for which a local excision was performed followed by adjuvant radiotherapy. Two years after this event, the patient presented with another perianal lession, which according to the histopathological result was a basal cell carcinoma; local excision was the only treatment performed for this malignancy.

Cutaneous Angiosarcoma of the Scalp Masquerading as a Squamous Cell Carcinoma: Case Report and Literature Review

2012 ◽  
Vol 16 (3) ◽  
pp. 187-190 ◽  
Author(s):  
Padmanabhan Dhanasekar ◽  
Vilvapathy Senguttuvan Karthikeyan ◽  
Nagarajan Rajkumar ◽  
Sarath Chandra Sistla ◽  
S. Manwar Ali ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Local Excision ◽  
Squamous Cell ◽  
Wide Local Excision ◽  
Kaposi Sarcoma ◽  
Neck Region ◽  
The Elderly ◽  
Elderly Male

Background: Cutaneous angiosarcoma is a rare tumor of the elderly male, most commonly affecting the head and neck region. It is difficult to differentiate this tumor from hemangiomas, hemangioblastomas, Kaposi sarcoma, squamous cell carcinoma and anaplastic melanomas. Methods: Case report and review of pertinent English medical literature. Case summary: We report a case of a 60-year-old male presenting with multiple nodules over the scalp where a preoperative histopathologic diagnosis of squamous cell carcinoma was made by wedge biopsy from the tumor. Postoperative histopathology and immuno histochemistry of the wide local excision specimen proved the tumor to be cutaneous angiosarcoma and the patient completed adjuvant radiotherapy. He is now on regular follow-up for 1 year without recurrence. Conclusions: Cutaneous angiosarcoma must be kept in mind in view of its rarity especially in extensive involvement of the scalp by malignancy. The primary treatment is wide local excision with adequate skin cover and adjuvant chemotherapy and radiotherapy in positive margins and lymph node metastasis.

scholarly journals Clinico-Histological presentation of Head and Neck Lesions in a Tertiary Care Hospital

2021 ◽  
Vol 25 (1) ◽  
pp. 21-25
Author(s):  
Mohammad Sajjad Kattak ◽  
Abdul Ghafoor ◽  
Rafi Ullah ◽  
Asif Mehmmod ◽  
Mohammad Iqbal ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Basal Cell ◽  
Histopathological Diagnosis ◽  
Care Hospital ◽  
Malignant Lesions

Objective: This study aimed to see the clinical presentation and histological pattern of various head and neck lesions.Materials and Methods: This descriptive study was conducted in the Department of Pathology, Bannu Medical College in association with the Department of Surgery and ENT, Khalifa Gul Nawaz Teaching Hospital, Bannu. A total of 184 cases of head and neck lesions biopsy were subjected to histopathological diagnosis. Patients' age, gender, anatomical location, and other relevant necessary clinical findings were recorded on an already designed proforma. All biopsies were received in 10% buffered formalin, fixed overnight, and processed for histopathological examination and diagnosis. Inclusion criteria were patients with head and neck lesions including skin, salivary gland, lymph node, and oral cavity of any age and gender. Exclusion criteria were thyroid, nasal cavity lesions, autolysed, and insufficient biopsy specimen. Results: In this study, the mean age was 28.58 ± 17.34 years, and the age range was from 10 to 80 years. The male-to-female ratio was 1.3:1. The most common age group was 36-45 years followed by 46-55 years and 26-35 years etc. The most common inflammatory lesion was granulomatous lymphadenitis 14.67% followed by reactive lymphoid hyperplasia 9.23%. Common benign lesions were pleomorphic adenoma 5.97% followed by lipoma and hemangioma 3.80% and 3.26% respectively. Amongst malignant lesions basal cell carcinoma 23.91% of the face was the commonest lesion followed by squamous cell carcinoma 22.28% of the oral cavity. Conclusion: This study show spectrum of lesions from inflammatory to benign and malignant, occurring in the head and neck region. Malignant lesions are more common as compared to benign and inflammatory lesions, basal cell carcinoma of the skin is the commonest malignant lesion followed by squamous cell carcinoma of the skin and oral cavity.

A RARE CASE OF PRIMARY SQUAMOUS CELL CARCINOMA AT ILEOSTOMY SITE: CASE REPORT

2021 ◽  
pp. 58-59
Author(s):  
Hitesh Soni ◽  
Saurabh Kalia ◽  
J M Mehta ◽  
Manisha Agarwal
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Local Excision ◽  
Squamous Cell ◽  
Wide Local Excision ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
Primary Squamous Cell Carcinoma ◽  
En Bloc

Primary squamous cell carcinoma at ileostomy site is extremely rare and there are only eight reported cases prior to our report. The present case report describes a patient of ileostomy formation 12 years prior to evaluation after total colectomy who now presented with mass at stomal and parastomal site and underwent biopsy and Positron emission tomography (PET) scan. Tumor was suspected and hence wide local excision with en bloc resection of the ileostomy and ileo-rectal anastomosis was done and histopathology showed differentiated Squamous cell carcinoma (SCC), Grade 1. This case underlines the need of regular follow-up of patients with stomas to allow the timely detection of stomal problems and the early diagnosis and management of the rare complication of parastomal squamous-cell carcinoma. Also, persistent peristomal ulcerations and proliferative lesions must undergo biopsies to rule out malignancy. Wide local excision of the carcinoma with en bloc resection of ileostomy and formation of new ileostomy at a different site is usually done to manage such cases.

SQUAMOUS CELL CARCINOMA OF THE TEMPORAL REGION MANAGED WITH WIDE LOCAL EXCISION AND FREE LATERAL THIGH FLAP COVER

2021 ◽  
pp. 72-73
Author(s):  
Surya Rao Rao Venkata Mahipathy ◽  
Narayanamurthy Sundaramurthy ◽  
Alagar Raja Durairaj ◽  
Anand Prasath Jayachandiran ◽  
Suresh Rajendran
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Local Excision ◽  
Squamous Cell ◽  
Wide Local Excision ◽  
Chemical Exposure ◽  
Temporal Region ◽  
The Face ◽  
Lateral Thigh ◽  
Flap Cover

Squamous cell carcinoma is the second most common form of cutaneous malignancy and is usually due to exposure of ultraviolet radiation (UV-B), inammation (from trauma or burns), chemical exposure and immunosuppression. Squamous cell carcinoma is a malignant proliferation of the epidermal keratinocyte. It is most common in elderly Caucasian population. Lesions occur most commonly on the face, neck, ears, hands and arms but metastases are rare. Here, we present a case of an elderly gentleman who came with an ulceroproliferative lesion of the left temporal scalp for 6 months. Biopsy proved to be a well differentiated squamous cell carcinoma. Wide local excision was done and the defect was closed using a free thin lateral thigh ap.

scholarly journals American Joint Committee on Cancer Staging and Clinicopathological High-Risk Predictors of Ocular Surface Squamous Neoplasia: A Study From a Tertiary Eye Center in India

2014 ◽  
Vol 138 (11) ◽  
pp. 1488-1494 ◽  
Author(s):  
Sheetal Chauhan ◽  
Seema Sen ◽  
Anjana Sharma ◽  
Radhika Tandon ◽  
Seema Kashyap ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Intraepithelial Neoplasia ◽  
Tnm Staging ◽  
Clinicopathological Features ◽  
Histopathological Diagnosis ◽  
Ocular Surface Squamous Neoplasia ◽  
Adjacent Structures ◽  
Orbital Invasion

Context Ocular surface squamous neoplasia (OSSN) is the most common tumor of conjunctival epithelium associated with risk of permanent visual impairment. It includes conjunctival intraepithelial neoplasia and squamous cell carcinoma. Although American Joint Committee on Cancer–TNM (AJCC-TNM) staging is commonly used in various tumors, it has only recently been described for OSSN. Objectives To evaluate the prognostic relevance of AJCC-TNM staging and the clinicopathological features in OSSN. Design Sixty-four histopathologically proven cases of OSSN (20 conjunctival intraepithelial neoplasia and 44 squamous cell carcinoma) were included in the study. The AJCC-TNM staging and clinicopathological features of OSSN cases were recorded. Patients were followed up for 17 to 40 months (median, 32 months). Univariate and multivariate analyses were performed to determine the prognostic value of various clinicopathological features. Results Longer sunlight exposure (P = .01), diffuse growth pattern (P = .02), larger tumor size (≥2 cm) (P = .03), histopathological diagnosis of squamous cell carcinoma (P = .02), and orbital invasion or invasion of adjacent structures (T3 or T4) (P < .001) emerged as significant predictors of reduced recurrence-free survival. Using multivariate analysis, a higher T category (T3 or T4) was the most important prognostic indicator of a poor outcome. Conclusions A higher T category (T3 or T4) is an important predictor of clinical outcome, and the use of the AJCC-TNM staging system is recommended in the management of all patients with OSSN. Longer sunlight exposure, larger tumor size (≥2 cm), orbital invasion or invasion of adjacent structures (T3 or T4), and a histopathological diagnosis of squamous cell carcinoma are other clinicopathological features of prognostic relevance in patients with OSSN.

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