Nonadherence and factors affecting adherence of diabetic patients to anti-diabetic medication in Assela General Hospital, Oromia Region, Ethiopia

Abstract Objectives Hypoglycemia is the most common adverse effect of sulfonylureas (SUs) and a major concern when using these drugs. Transcription factor 7-like 2 (TCF7L2) rs7903146 C>T polymorphism is an established and well characterized genetic marker of type 2 diabetes (T2DM) risk. The aim of the present study was to analyze the potential association of TCF7L2 rs7903146 C>T polymorphism with SU-induced hypoglycemia in a well characterized cohort of SU-treated patients previously genotyped for cytochrome P450 2C9 (CYP2C9) and P450 oxidoreductase (POR). Methods The study group consisted of 176 SU-treated T2DM patients of whom 92 had experienced at least one drug-associated hypoglycemic event. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used for TCF7L2 rs7903146 genotyping. Results TCF7L2 rs7903146 C>T genotype and allele frequency did not differ between cases and controls (p=0.745 and 0.671, respectively). In logistic regression analysis adjusted for other factors affecting hypoglycemia, including CYP2C9 and POR genotypes, TCF7L2 rs7903146 C>T polymorphism did not increase the risk of hypoglycemia (OR=1.238, 95% C.I.=0.750–2.044, p=0.405). Conclusions TCF7L2 rs7903146 C>T polymorphism is not associated with SU-induced hypoglycemia. Identifying additional gene polymorphisms associated with SU-induced hypoglycemia is crucial for improving T2DM patient therapy with SUs.

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Factors affecting complementary and alternative medicine (CAM) use in adult diabetic patients: A systematic review using the theoretical domains framework

Research in Social and Administrative Pharmacy ◽

10.1016/j.sapharm.2022.01.001 ◽

2022 ◽

Author(s):

Abdulaziz Saud Alzahrani ◽

Sheila M. Greenfield ◽

Vibhu Paudyal

Keyword(s):

Systematic Review ◽

Alternative Medicine ◽

Complementary And Alternative Medicine ◽

Theoretical Domains Framework ◽

Diabetic Patients ◽

Factors Affecting ◽

Cam Use ◽

Complementary And Alternative

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Job motivation and some factors affecting job motivation of office and support staffs at Dong Thap General hospital in 2017

Journal of Health and Development Studies ◽

10.38148/jhds.0403skpt20-028 ◽

2020 ◽

Vol 04 (03) ◽

pp. 9-17

Author(s):

Quynh Pham ◽

◽

Minh Tuan Le ◽

Thanh Phung ◽

Thi Huyen Chang Pham

Keyword(s):

Job Satisfaction ◽

General Hospital ◽

Working Environment ◽

Average Score ◽

Cross Sectional ◽

Factors Affecting ◽

Research Results ◽

Job Motivation ◽

The Board Of Directors ◽

Intrinsic Job Satisfaction

The study was conducted with 02 objectives to describe and analyze some factors affecting the motivation of office and support staffs working at Dong Thap General Hospital in 2017. The research design is cross-sectional, combining quantitative and qualitative methods. Research results show that, the motivation average score of office and support staffs with the general motivation; burnout; job satisfaction; intrinsic job satisfaction; organizational commitment; conscientiousness; timeliness and attendance oscillate from 2.91 to 3.5. The motivation average score of office and support staffs with burnout is lowest and the motivation average score of office and support staffs with conscientiousness is highest. Some factors affecting the motivation of office and support staffs are income policies; training opportunities; satisfaction of colleagues and managers; working environment; equipment and facilities. The research results provide evidence to help the Board of Directors to develop solutions to improve the motivation of office and support staffs in the future. Keywords: job motivation, office and support staffs, hospital.

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Factors affecting poor attendance for outpatient physiotherapy by patients discharged from Mthatha General Hospital with a stroke

South African Journal of Physiotherapy ◽

10.4102/sajp.v69i3.29 ◽

2013 ◽

Vol 69 (3) ◽

Cited By ~ 6

Author(s):

N.P. Ntamo ◽

D. Buso ◽

B. Longo-Mbenza

Keyword(s):

Health Care ◽

General Hospital ◽

Specific Reference ◽

Clinical Impression ◽

Long Term Effects ◽

Structured Interviews ◽

Stroke Patients ◽

Long Distance ◽

Factors Affecting ◽

Physiotherapy Department

Background: Stroke is a major cause of disability inthe world and its long term effects require adherence to physiotherapyprotocols for optimal rehabilitation. Clinical impression of data fromMthatha General Hospital (MGH) Physiotherapy Department revealedthat there was poor attendance of outpatient physiotherapy by strokepatients discharged from MGH and this had negative effects on outcomesand health care costs.Objective: To determine the extent and the socio-demographic reasonsfor poor attendance for outpatient physiotherapy by stroke patients.Methods: An observational descriptive study was conducted using arandomly selected sample of 103 stroke patients from a population of 139who attended physiotherapy in MGH in 2007. Structured interviews wereconducted and SPSS was used for data analysis.Results: The majority (86%) of patients did not attend physiotherapy until discharge from the Physiotherapy Department. Themajor reasons for poor attendance were lack of finances (95%), migration to other areas (36%), and living a long distance fromMGH (38%).Conclusion: Almost 9 out of 10 stroke patients fail to attend for outpatient physiotherapy because of lack of finances.Recommendation: Development of a Provincial Rehabilitation Policy with specific reference to decentralization of rehabilitationservices to address unavailability of physiotherapy services at clinics and health care centers which are proximal to the patients’residential areas is recommended.

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FACTORS AFFECTING PROGNOSIS OF TUBERCULOUS MENINGITIS IN SAIFUL ANWAR GENERAL HOSPITAL MALANG

MNJ (Malang Neurology Journal) ◽

10.21776/ub.mnj.2020.006.01.1 ◽

2020 ◽

Vol 6 (1) ◽

pp. 1-4

Author(s):

Badrul Munir ◽

Firman Prayudi ◽

Catur Ari Setianto ◽

Siswanto S

Keyword(s):

General Hospital ◽

Tuberculous Meningitis ◽

Factors Affecting

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Evaluating Knowledge and Stages of Nutritional Behavior Change in Diabetic Patients Covered by Comprehensive Health Service Centers in Ghayenat City in 2020

Modern Care Journal ◽

10.5812/modernc.117692 ◽

2021 ◽

Vol 18 (3) ◽

Author(s):

Abbas Khazaeinejad ◽

Fatemeh Salmani ◽

Mitra Moodi

Keyword(s):

Logistic Regression ◽

Health Service ◽

Behavior Change ◽

Metabolic Diseases ◽

Ordinal Logistic Regression ◽

Diabetic Patients ◽

Factors Affecting ◽

Training Course ◽

Nutritional Behavior ◽

Comprehensive Health

Background: Diabetes is one of the most common chronic and non-communicable metabolic diseases and one of the major public health problems. Lifestyle and diet are remarkable factors in controlling diabetes. Objectives: This study aimed to determine the level of knowledge and stages of nutritional behavior change in diabetic patients. Methods: In this descriptive-analytical study, a simple random sampling method was used to select 330 diabetic patients covered by comprehensive health service centers in Ghayenat city, South Khorasan Province, Iran. The research instrument addressed the participants’ demographic information, knowledge, and stages of nutritional behavior change in diabetic patients. The ordinal logistic regression was used to examine factors affecting behavior change. In this regard, the significance level was set to be P < 0.05. Results: The participants’ mean age was 57.86 ± 11.72 years, and 63.7% of the patients were female. The mean score of knowledge was 15.73 ± 2.61, and 52.8, 16.9, 8.9, 11.3, and 10.1 percent of the participants were in the maintenance, action, preparation, contemplation, and pre-contemplation stages. The ordinal Logistic regression model revealed that the main factors affecting behavior change were knowledge, level of income, and a family member with diabetes (P < 0.05). Conclusions: Given that about two-thirds of diabetic patients take no training course on diabetes, that above forty percent of these individuals have no proper knowledge about the disease, and that half of the patients are in the pre-maintenance stages of behavior change, holding a training course is of paramount importance for patients.

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