Implementing strategic response framework for the control of Zika virus infection: World Health Organization

2016 ◽  
Vol 9 (6) ◽  
pp. 408
Author(s):  
SaurabhR Shrivastava ◽  
PrateekS Shrivastava ◽  
Jegadeesh Ramasamy
2020 ◽  
Vol 11 (4) ◽  
pp. 257-265
Author(s):  
Manoel Alfredo Curvelo Sarno ◽  
Luciana Carla Belém dos Santos ◽  
Priscila Pinheiro Ribeiro Lyra ◽  
Carlos Mauricio Cardeal Mendes ◽  
Patrícia Ribeiro de Oliveira ◽  
...  

Introduction: The association between the increased incidence of microcephaly and the epidemic outbreak of Zika virus infection (ZIKV) in Brazil between 2015 and 2016 was observed by many authors. World Health Organization declared it as a public health emergency of international concern. Maternal infection with the Zika virus can be transmitted vertically and lead to Congenital Zika Syndrome (CZS) in infants. So that it is important to investigate the clinical-epidemiological profile of the mothers and their newborns. Aims: To characterize the clinical- epidemiological profile of pregnant women associated with presumed ZIKV in pregnancy and their newborns diagnosed with microcephaly at birth and associated with CZS. Methods: A sectional study, using medical record data, between September 2015 and June 2016. Results: 82 cases of microcephaly were reported in maternity during this period. Of these, 32 cases were excluded because they did not fit the new microcephaly criteria according to the World Health Organization (WHO) and the Ministry of Health of Brazil. The mean maternal age was 25 years, varying from 13 and 43 years old; exanthema was the only symptom related to Zika virus infection and it was observed in 60% (27/45) of the pregnancies, which occurred predominantly during the first or the second trimester of pregnancy. Other mothers were asymptomatic. Related to the newborns, 62% (31/50) were female; 32% (16/50) were low weight; 2% (1/50) were premature. Neonatal brain ultrasound showed 70,4% (31/44) of the neonates with abnormal findings, mainly calcifications that occurred in 87% (27/31). 29 newborns were submitted to fundoscopy examinations and 38% (11/29) were abnormal. Conclusion: Despite the majority of pregnant women did not have classic symptoms of arboviruses and because of this the suspicion and confirmation of Zika viruses infection through serologies are difficult in clinical practice, it is important to understand clinical and epidemiological characteristics related to Zika viruses infection and the CZS to allow mapping where preventive measures should be directed and better investigated as well as to offer an adequate follow-up to the infected neonates according to their outcomes.


2016 ◽  
Vol 10 (5) ◽  
pp. 707-712 ◽  
Author(s):  
Kelly G. Vest

AbstractSince February 2015, Zika virus has spread throughout the Western Hemisphere, starting in Brazil. As of March 2016, autochthonous transmission has been reported in at least 31 countries or territories. For countries in the Americas, the spread of Zika virus, a previously unfamiliar disease, follows similar emerging infection introductions of West Nile virus and Chikungunya virus and their spread throughout the American continents and the Caribbean nations. The Pan American Health Organization and the World Health Organization have issued alerts and a Public Health Emergency of International Concern announcement related to the recent cluster of microcephaly cases and other neurological disorders in Brazil that are temporally associated with Zika virus, which highlights the possible adverse impact of viral infection. This article provides an overview of the Zika virus infection and presents the historical background of the virus, a description of the pathogen, the epidemiology and clinical spectrum of Zika virus infection, diagnosis and treatment approaches, and prevention and control measures. Understanding what is known about the virus and its clinical presentation will assist in prevention, detection, and response measures to reduce and control the spread of the virus throughout the Western Hemisphere. (Disaster Med Public Health Preparedness. 2016;page 1 of 6)


2021 ◽  
Vol 11 (2-S) ◽  
pp. 1-3
Author(s):  
A Otljanski ◽  
K Kipevska

In 2019 year the world was attacked with corona virus (SARS-CoV-2) and in march 2020, the World Health Organization (WHO) declared the COVID-19 outbreak a pandemic.The symptoms and clinical state in this COVID-19 infection was different, from asymptomatic to mild and severe symptoms, which presented different form of disease: mild, moderate or severe, with or without complications. We presented case with COVID 19 pneumonia as one of the form of COVID infection, with diagnosis, treatment and all investigations we done in our hospital. With complex treatment of this virus infection we successful improved the clinical state of patients with COVID 19 pneumonia. Keywords: coronavirus, SARS-CoV-2, COVID-19, COVID 19 pneumonia


2018 ◽  
Vol 99 (3) ◽  
pp. 780-782 ◽  
Author(s):  
Matthew J. Ward ◽  
Jackeline Alger ◽  
Mabel Berrueta ◽  
Harry Bock ◽  
Pierre Buekens ◽  
...  

2019 ◽  
Vol 4 (2) ◽  
pp. 68 ◽  
Author(s):  
Matthew H. Collins

Zika virus is an emerging mosquito-borne flavivirus that recently caused a large epidemic in Latin America characterized by novel disease phenotypes, including Guillain-Barré syndrome, sexual transmission, and congenital anomalies, such as microcephaly. This epidemic, which was declared an international public health emergency by the World Health Organization, has highlighted shortcomings in our current understanding of, and preparation for, emerging infectious diseases in general, as well as challenges that are specific to Zika virus infection. Vaccine development for Zika virus has been a high priority of the public health response, and several candidates have shown promise in pre-clinical and early phase clinical trials. The optimal selection and implementation of imperfect serologic assays are among the crucial issues that must be addressed in order to advance Zika vaccine development. Here, I review key considerations for how best to incorporate into Zika vaccine trials the existing serologic tools, as well as those on the horizon. Beyond that, this discussion is relevant to other intervention strategies to combat Zika and likely other emerging infectious diseases.


Author(s):  
KANAAN AL-TAMEEMI ◽  
RAIAAN KABAKLI

This review highlights the Zika virus which is considered a global concern due to its rapid pandemic potential and effect on humans, and according to its pandemic status, the World Health Organization declared on February 2016 it as a “Public Health Emergency of International Concern.” Therefore, we define the epidemiology of Zika virus in addition to its pathogenesis, diagnostic techniques, and treatment.


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